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The map label for this gene is metH [H]

Identifier: 160874127

GI number: 160874127

Start: 1198732

End: 1202466

Strand: Reverse

Name: metH [H]

Synonym: Sbal195_1007

Alternate gene names: 160874127

Gene position: 1202466-1198732 (Counterclockwise)

Preceding gene: 160874138

Following gene: 160874123

Centisome position: 22.49

GC content: 51.94

Gene sequence:

>3735_bases
ATGACGATACCCTCTACCAAAGCCGGCCAGATATTGGCAGACATTCGTAAACAGCTTGCTGAGCGCATTCTAATCTTAGA
CGGTGCCATGGGCACTATGATCCAAGACCACAAGCTCGAAGAAGAGGATTATCGCGGCGAACGCTTTAAAGATTGGCACA
CTGACGTCAAAGGCAACAACGATTTATTGGTGTTATCGCAACCCCACATCATCAAACAGATTCACACCGACTACTTAAAC
GCCGGTGCCGACATCATTGAAACCAACACCTTTAATGCTACTACTATCGCCATGGCCGACTACGACATGCAGTCGCTGTC
CGCCGAAATTAACTTAGCCGGCGCCCGTCTTGCCCGTGAAGCCTGTGATGAAGTGTTTGCTGCCACAGGCATTCCGCGCT
ACGTCGCTGGTGTGTTAGGCCCCACTAACCGTACGTGTTCGATTAGCCCAGATGTGAACGACCCTGGCTATCGCAACGTC
AGCTTCGATGAGTTAGTCAGCGCTTACCGAGAATCCACTAAGGCGCTGATTGAAGGCGGCGCGGATATCATTATGGTCGA
GACCATATTCGATACCTTAAATGCCAAAGCCGCACTGTTTGCGATTGAATCGGTATTTGATGACTTATTTGGTCAGCATT
CTAAAGACAGATTGCCAATCATGATTTCGGGCACTATTACCGATGCCTCAGGCCGTACCCTTACGGGTCAAACCACCGAA
GCCTTTTATAATTCCCTGCGCCATATCAAGCCCTTATCTATCGGCCTTAACTGTGCGCTTGGGCCAAAAGAGCTGCGCCC
GTATGTGGAAGAATTATCGCGCATCAGTGAGTGTTATGTGTCGGCGCATCCGAACGCGGGCCTGCCGAACGAATTTGGCG
GCTACGATGAAACCCCAGAAGACATGGCGAATGTGATCGAAGATTGGGCGCGCGAAGGCATGCTCAATATTATCGGTGGT
TGCTGTGGTAGTACGCCTGAACATATCCGCGTTATTCGCGAAGCGGTCGACAGACATAACCCGCGCGTTTTACCCGATAT
CCCCGTCGCTTGCCGCTTAGCCGGTTTGGAACCGCTGACTATCGATGCACAATCCCTGTTCGTTAACGTGGGTGAGCGCA
CCAACGTCACAGGTTCGGCCAAGTTTTTAAAGCTGATCAAAGACGGTAAGTTTGAGCAAGCGCTCGATGTAGCCCGCGAG
CAGGTTGAAAGCGGCGCGCAGATCATCGACATCAACATGGACGAAGGCATGCTCGATGGCGCCGAGATCATGCACAAGTT
TTTAAACTTGATAGCCTCTGAGCCCGACATCAGCCGCGTGCCGATTATGATCGACTCCTCTAAGTGGGAAGTGATCGAAG
CTGGCCTCAAATGCATTCAAGGCAAGGGCATAGTTAACTCGATTTCCCTTAAAGAAGGCGAAGCCAAGTTTATTGAGCAA
GCCACCTTAGTAAAACGCTACGGCGCGGCGGCCATTATCATGGCGTTCGACGAACAAGGTCAGGCCGATACTAAGGCACG
TAAAATCGAAATCTGTACCCGCGCCTATCGGGTTCTGGTCGATAAGGTCGGCTTTCCGCCAGAAGACATCATCTTCGACC
CGAACATTTTTGCCATCGCCACGGGTATCGATGAACACGACAACTATGCCGTCGATTTTATTGATGCCATTAAAGCGATT
AAAGCCACCCTGCCCCACGCAATGATTTCGGGCGGCGTATCAAACGTGTCGTTCTCGTTTCGCGGTAACAACCCAGTGCG
CGAAGCGATTCACGCGGTATTCCTGTACCATGCCATCAAAGTCGGCATGGACATGGGCATTGTCAACGCGGGCCAGTTAG
CCATTTACGACGATATCGATCCTGAGCTTAAAGTACGAGTCGAAAACGTGGTGCTTAACTTGCCCTGCCCAGTCGAAGGC
TCAAGCAATACCGAGCAGTTACTTGAAATCGCGGAGAAATTCCGCGGTGATGGCGCGCAGGTGGGTAAGAAAGAAGATTT
AGAATGGCGCAGCTGGCCGGTTAGCCAACGCTTATCCCATGCGCTCGTCAAAGGCATTACCGAATTTATCGATGAAGATA
CCGAAGCCGCTCGCCAAGAAGCGAAACGTCCGCTGGATGTGATTGAAGGCGCCTTGATGGACGGCATGAACGTGGTCGGT
GACTTGTTCGGCTCGGGTAAGATGTTCCTGCCACAGGTGGTGAAATCGGCGCGAGTGATGAAAAAAGCCGTGGCTTACTT
AAACCCCTATATCGAGCTGGAAAAGGTCGAAGGCCAATCTAACGGCAAGATTTTGATGGTGACAGTAAAAGGAGACGTGC
ACGATATCGGCAAAAATATCGTCGGCGTGGTGCTCGCCTGTAACGGTTTTGAGGTATTCGATTTAGGTGTGATGGTGTCG
GTGGAGCGAATTCTCGACGCTGTGAAAGAACACAATATCGATATCATCGGCATGTCGGGCCTCATCACGCCGAGTCTGGA
CGAGATGGTGCATAACGTGAAAACCTTCCACCGTGAAGGCTTAACCATTCCGGCGATCATCGGCGGCGCGACTTGCTCTA
AAATCCACACAGCGGTGAAGATTGCGCCCCATTATCCCCATGGCGCCATTTATATCGCCGATGCGTCCCGCGCCGTGCCT
ATGGTGAGTAAGCTCATCAACAACGAGACCCGCCAAGCGACCATAGACGAAACCTATGCCGAATACGACGACATGCGCAC
TAAGCGTTTATCTCAAGCCAAGCGCAAAGAAATAGTGTCACTCGAAGCGGCGCGTGATAACCGCTGCCAACACGATTGGG
CCAACTACACCCCGTTCACGCCAAACGTGCTCGGGCGCCAAGTCTTTGATAATTATCCATTAGAAGATTTAGTTGAGCGT
ATCGACTGGACACCGTTTTTCCGCTCGTGGGAATTGCATGGCCATTACCCTGAAATCCTCACCGATAAAGTGGTCGGCGT
CGAGGCGCAAAAGCTATTCGCCGATGGTCAGGCCATGCTCAAACAAATCATCGAAGAAAAGTGGCTCACGGCGAAAGCGG
TTATTGGCTTATTCCCTGCCAATACCGTCAATTACGACGACATTGAGCTGTATACTGACGAGTCGCGCACCACAGTTGAA
ATGACCACACATCACCTGCGGATGCAGCTTGAGCGTGTCGGTAATGACAACTTCTGCCTATCTGACTTTGTTGCGCCAAA
AGACTCTGGCGTCGCCGATTACATGGGCGGCTTTGCGGTGACCACGGGCCACGGCATAGACGAACATGTGGCGCGTTTTG
AAGCCAACCACGACGACTACAACGCCATCATGCTCAAGTGCTTAGCCGACCGTTTGGCCGAAGCCTTTGCCGAGCGGATG
CACGAACGGGTGCGTAAAGAGTTTTGGGGTTATGCGGCCGACGAGCAGTTAAGCAACGAAGCCTTAATCCGCGAGAAATA
CAAAGGTATACGCCCCGCACCGGGTTACCCAGCATGCCCAGATCATACAGAAAAAGGCTTGTTATGGGACTTGCTCAAGC
CCGATGAAACTATCGACTTGAACATCACCGAAAGCTACGCCATGTTCCCCACAGCGGCAGTATCGGGCTGGTATTTCGCC
CACCCGAAATCGCGCTACTTTGGCGTGAGTAACATAGGCCGCGATCAAGTGGAAGATTATGCCAAGCGTAAAGGGATGAG
CATTGCGGAAACGGAGAAGTGGCTGGCGCCAGTGTTGGATTATGATCCCGAGTGA

Upstream 100 bases:

>100_bases
GAGAGCCGATATCTGGACTGCACAACACGCTTTACCCTGCACTTAGCATAACAAGGGTCGATGCTTGGACTTAACTTAGC
TGTATTTAAGGTAATTATTT

Downstream 100 bases:

>100_bases
TTGGGATCTGCAATCACCCGCAGGGCTTAAACTTTCAAACTTCGTTTGAATTAAGCGTTAAAGTCGTGGGGCTTCACCCC
ACACCCGATGTTGCTGGTTC

Product: B12-dependent methionine synthase

Products: NA

Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12 dependent; MS [H]

Number of amino acids: Translated: 1244; Mature: 1243

Protein sequence:

>1244_residues
MTIPSTKAGQILADIRKQLAERILILDGAMGTMIQDHKLEEEDYRGERFKDWHTDVKGNNDLLVLSQPHIIKQIHTDYLN
AGADIIETNTFNATTIAMADYDMQSLSAEINLAGARLAREACDEVFAATGIPRYVAGVLGPTNRTCSISPDVNDPGYRNV
SFDELVSAYRESTKALIEGGADIIMVETIFDTLNAKAALFAIESVFDDLFGQHSKDRLPIMISGTITDASGRTLTGQTTE
AFYNSLRHIKPLSIGLNCALGPKELRPYVEELSRISECYVSAHPNAGLPNEFGGYDETPEDMANVIEDWAREGMLNIIGG
CCGSTPEHIRVIREAVDRHNPRVLPDIPVACRLAGLEPLTIDAQSLFVNVGERTNVTGSAKFLKLIKDGKFEQALDVARE
QVESGAQIIDINMDEGMLDGAEIMHKFLNLIASEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISLKEGEAKFIEQ
ATLVKRYGAAAIIMAFDEQGQADTKARKIEICTRAYRVLVDKVGFPPEDIIFDPNIFAIATGIDEHDNYAVDFIDAIKAI
KATLPHAMISGGVSNVSFSFRGNNPVREAIHAVFLYHAIKVGMDMGIVNAGQLAIYDDIDPELKVRVENVVLNLPCPVEG
SSNTEQLLEIAEKFRGDGAQVGKKEDLEWRSWPVSQRLSHALVKGITEFIDEDTEAARQEAKRPLDVIEGALMDGMNVVG
DLFGSGKMFLPQVVKSARVMKKAVAYLNPYIELEKVEGQSNGKILMVTVKGDVHDIGKNIVGVVLACNGFEVFDLGVMVS
VERILDAVKEHNIDIIGMSGLITPSLDEMVHNVKTFHREGLTIPAIIGGATCSKIHTAVKIAPHYPHGAIYIADASRAVP
MVSKLINNETRQATIDETYAEYDDMRTKRLSQAKRKEIVSLEAARDNRCQHDWANYTPFTPNVLGRQVFDNYPLEDLVER
IDWTPFFRSWELHGHYPEILTDKVVGVEAQKLFADGQAMLKQIIEEKWLTAKAVIGLFPANTVNYDDIELYTDESRTTVE
MTTHHLRMQLERVGNDNFCLSDFVAPKDSGVADYMGGFAVTTGHGIDEHVARFEANHDDYNAIMLKCLADRLAEAFAERM
HERVRKEFWGYAADEQLSNEALIREKYKGIRPAPGYPACPDHTEKGLLWDLLKPDETIDLNITESYAMFPTAAVSGWYFA
HPKSRYFGVSNIGRDQVEDYAKRKGMSIAETEKWLAPVLDYDPE

Sequences:

>Translated_1244_residues
MTIPSTKAGQILADIRKQLAERILILDGAMGTMIQDHKLEEEDYRGERFKDWHTDVKGNNDLLVLSQPHIIKQIHTDYLN
AGADIIETNTFNATTIAMADYDMQSLSAEINLAGARLAREACDEVFAATGIPRYVAGVLGPTNRTCSISPDVNDPGYRNV
SFDELVSAYRESTKALIEGGADIIMVETIFDTLNAKAALFAIESVFDDLFGQHSKDRLPIMISGTITDASGRTLTGQTTE
AFYNSLRHIKPLSIGLNCALGPKELRPYVEELSRISECYVSAHPNAGLPNEFGGYDETPEDMANVIEDWAREGMLNIIGG
CCGSTPEHIRVIREAVDRHNPRVLPDIPVACRLAGLEPLTIDAQSLFVNVGERTNVTGSAKFLKLIKDGKFEQALDVARE
QVESGAQIIDINMDEGMLDGAEIMHKFLNLIASEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISLKEGEAKFIEQ
ATLVKRYGAAAIIMAFDEQGQADTKARKIEICTRAYRVLVDKVGFPPEDIIFDPNIFAIATGIDEHDNYAVDFIDAIKAI
KATLPHAMISGGVSNVSFSFRGNNPVREAIHAVFLYHAIKVGMDMGIVNAGQLAIYDDIDPELKVRVENVVLNLPCPVEG
SSNTEQLLEIAEKFRGDGAQVGKKEDLEWRSWPVSQRLSHALVKGITEFIDEDTEAARQEAKRPLDVIEGALMDGMNVVG
DLFGSGKMFLPQVVKSARVMKKAVAYLNPYIELEKVEGQSNGKILMVTVKGDVHDIGKNIVGVVLACNGFEVFDLGVMVS
VERILDAVKEHNIDIIGMSGLITPSLDEMVHNVKTFHREGLTIPAIIGGATCSKIHTAVKIAPHYPHGAIYIADASRAVP
MVSKLINNETRQATIDETYAEYDDMRTKRLSQAKRKEIVSLEAARDNRCQHDWANYTPFTPNVLGRQVFDNYPLEDLVER
IDWTPFFRSWELHGHYPEILTDKVVGVEAQKLFADGQAMLKQIIEEKWLTAKAVIGLFPANTVNYDDIELYTDESRTTVE
MTTHHLRMQLERVGNDNFCLSDFVAPKDSGVADYMGGFAVTTGHGIDEHVARFEANHDDYNAIMLKCLADRLAEAFAERM
HERVRKEFWGYAADEQLSNEALIREKYKGIRPAPGYPACPDHTEKGLLWDLLKPDETIDLNITESYAMFPTAAVSGWYFA
HPKSRYFGVSNIGRDQVEDYAKRKGMSIAETEKWLAPVLDYDPE
>Mature_1243_residues
TIPSTKAGQILADIRKQLAERILILDGAMGTMIQDHKLEEEDYRGERFKDWHTDVKGNNDLLVLSQPHIIKQIHTDYLNA
GADIIETNTFNATTIAMADYDMQSLSAEINLAGARLAREACDEVFAATGIPRYVAGVLGPTNRTCSISPDVNDPGYRNVS
FDELVSAYRESTKALIEGGADIIMVETIFDTLNAKAALFAIESVFDDLFGQHSKDRLPIMISGTITDASGRTLTGQTTEA
FYNSLRHIKPLSIGLNCALGPKELRPYVEELSRISECYVSAHPNAGLPNEFGGYDETPEDMANVIEDWAREGMLNIIGGC
CGSTPEHIRVIREAVDRHNPRVLPDIPVACRLAGLEPLTIDAQSLFVNVGERTNVTGSAKFLKLIKDGKFEQALDVAREQ
VESGAQIIDINMDEGMLDGAEIMHKFLNLIASEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISLKEGEAKFIEQA
TLVKRYGAAAIIMAFDEQGQADTKARKIEICTRAYRVLVDKVGFPPEDIIFDPNIFAIATGIDEHDNYAVDFIDAIKAIK
ATLPHAMISGGVSNVSFSFRGNNPVREAIHAVFLYHAIKVGMDMGIVNAGQLAIYDDIDPELKVRVENVVLNLPCPVEGS
SNTEQLLEIAEKFRGDGAQVGKKEDLEWRSWPVSQRLSHALVKGITEFIDEDTEAARQEAKRPLDVIEGALMDGMNVVGD
LFGSGKMFLPQVVKSARVMKKAVAYLNPYIELEKVEGQSNGKILMVTVKGDVHDIGKNIVGVVLACNGFEVFDLGVMVSV
ERILDAVKEHNIDIIGMSGLITPSLDEMVHNVKTFHREGLTIPAIIGGATCSKIHTAVKIAPHYPHGAIYIADASRAVPM
VSKLINNETRQATIDETYAEYDDMRTKRLSQAKRKEIVSLEAARDNRCQHDWANYTPFTPNVLGRQVFDNYPLEDLVERI
DWTPFFRSWELHGHYPEILTDKVVGVEAQKLFADGQAMLKQIIEEKWLTAKAVIGLFPANTVNYDDIELYTDESRTTVEM
TTHHLRMQLERVGNDNFCLSDFVAPKDSGVADYMGGFAVTTGHGIDEHVARFEANHDDYNAIMLKCLADRLAEAFAERMH
ERVRKEFWGYAADEQLSNEALIREKYKGIRPAPGYPACPDHTEKGLLWDLLKPDETIDLNITESYAMFPTAAVSGWYFAH
PKSRYFGVSNIGRDQVEDYAKRKGMSIAETEKWLAPVLDYDPE

Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate [H]

COG id: COG1410

COG function: function code E; Methionine synthase I, cobalamin-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

Organism=Homo sapiens, GI169790923, Length=1257, Percent_Identity=53.6197295147176, Blast_Score=1325, Evalue=0.0,
Organism=Escherichia coli, GI1790450, Length=1230, Percent_Identity=65.6910569105691, Blast_Score=1645, Evalue=0.0,
Organism=Escherichia coli, GI1786456, Length=327, Percent_Identity=22.9357798165138, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17535405, Length=1254, Percent_Identity=52.3923444976077, Blast_Score=1294, Evalue=0.0,

Paralogues:

None

Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR011005
- InterPro:   IPR003759
- InterPro:   IPR011822
- InterPro:   IPR000489
- InterPro:   IPR003726
- InterPro:   IPR004223 [H]

Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans [H]

EC number: =2.1.1.13 [H]

Molecular weight: Translated: 137998; Mature: 137866

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50974 ADOMET_ACTIVATION ; PS50970 HCY ; PS50972 PTERIN_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIPSTKAGQILADIRKQLAERILILDGAMGTMIQDHKLEEEDYRGERFKDWHTDVKGNN
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHCCCCCHHHHCCCCCCCC
DLLVLSQPHIIKQIHTDYLNAGADIIETNTFNATTIAMADYDMQSLSAEINLAGARLARE
CEEEEECCHHHHHHHHHHHHCCCCEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHH
ACDEVFAATGIPRYVAGVLGPTNRTCSISPDVNDPGYRNVSFDELVSAYRESTKALIEGG
HHHHHHHHCCCHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
ADIIMVETIFDTLNAKAALFAIESVFDDLFGQHSKDRLPIMISGTITDASGRTLTGQTTE
CCEEEHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEECCCHHH
AFYNSLRHIKPLSIGLNCALGPKELRPYVEELSRISECYVSAHPNAGLPNEFGGYDETPE
HHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
DMANVIEDWAREGMLNIIGGCCGSTPEHIRVIREAVDRHNPRVLPDIPVACRLAGLEPLT
HHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCEECCCCCHHHHCCCCCCEE
IDAQSLFVNVGERTNVTGSAKFLKLIKDGKFEQALDVAREQVESGAQIIDINMDEGMLDG
EEHHHHEEECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCH
AEIMHKFLNLIASEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISLKEGEAKFIEQ
HHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
ATLVKRYGAAAIIMAFDEQGQADTKARKIEICTRAYRVLVDKVGFPPEDIIFDPNIFAIA
HHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCEEEEE
TGIDEHDNYAVDFIDAIKAIKATLPHAMISGGVSNVSFSFRGNNPVREAIHAVFLYHAIK
ECCCCCCCHHHHHHHHHHHHHHHHCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
VGMDMGIVNAGQLAIYDDIDPELKVRVENVVLNLPCPVEGSSNTEQLLEIAEKFRGDGAQ
HCCCCCEECCCCEEEECCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCC
VGKKEDLEWRSWPVSQRLSHALVKGITEFIDEDTEAARQEAKRPLDVIEGALMDGMNVVG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
DLFGSGKMFLPQVVKSARVMKKAVAYLNPYIELEKVEGQSNGKILMVTVKGDVHDIGKNI
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHH
VGVVLACNGFEVFDLGVMVSVERILDAVKEHNIDIIGMSGLITPSLDEMVHNVKTFHREG
EEEEEEECCCEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCC
LTIPAIIGGATCSKIHTAVKIAPHYPHGAIYIADASRAVPMVSKLINNETRQATIDETYA
CEEEEEECCCHHHHHHHHEEECCCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHH
EYDDMRTKRLSQAKRKEIVSLEAARDNRCQHDWANYTPFTPNVLGRQVFDNYPLEDLVER
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHH
IDWTPFFRSWELHGHYPEILTDKVVGVEAQKLFADGQAMLKQIIEEKWLTAKAVIGLFPA
CCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHEECCC
NTVNYDDIELYTDESRTTVEMTTHHLRMQLERVGNDNFCLSDFVAPKDSGVADYMGGFAV
CCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCHHHHHCCEEE
TTGHGIDEHVARFEANHDDYNAIMLKCLADRLAEAFAERMHERVRKEFWGYAADEQLSNE
ECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCHH
ALIREKYKGIRPAPGYPACPDHTEKGLLWDLLKPDETIDLNITESYAMFPTAAVSGWYFA
HHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEECCCHHHCCHHHHCCEEEE
HPKSRYFGVSNIGRDQVEDYAKRKGMSIAETEKWLAPVLDYDPE
CCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TIPSTKAGQILADIRKQLAERILILDGAMGTMIQDHKLEEEDYRGERFKDWHTDVKGNN
CCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHCCCCCHHHHCCCCCCCC
DLLVLSQPHIIKQIHTDYLNAGADIIETNTFNATTIAMADYDMQSLSAEINLAGARLARE
CEEEEECCHHHHHHHHHHHHCCCCEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHH
ACDEVFAATGIPRYVAGVLGPTNRTCSISPDVNDPGYRNVSFDELVSAYRESTKALIEGG
HHHHHHHHCCCHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
ADIIMVETIFDTLNAKAALFAIESVFDDLFGQHSKDRLPIMISGTITDASGRTLTGQTTE
CCEEEHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEECCCHHH
AFYNSLRHIKPLSIGLNCALGPKELRPYVEELSRISECYVSAHPNAGLPNEFGGYDETPE
HHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
DMANVIEDWAREGMLNIIGGCCGSTPEHIRVIREAVDRHNPRVLPDIPVACRLAGLEPLT
HHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCEECCCCCHHHHCCCCCCEE
IDAQSLFVNVGERTNVTGSAKFLKLIKDGKFEQALDVAREQVESGAQIIDINMDEGMLDG
EEHHHHEEECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCH
AEIMHKFLNLIASEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISLKEGEAKFIEQ
HHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
ATLVKRYGAAAIIMAFDEQGQADTKARKIEICTRAYRVLVDKVGFPPEDIIFDPNIFAIA
HHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCEEEEE
TGIDEHDNYAVDFIDAIKAIKATLPHAMISGGVSNVSFSFRGNNPVREAIHAVFLYHAIK
ECCCCCCCHHHHHHHHHHHHHHHHCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
VGMDMGIVNAGQLAIYDDIDPELKVRVENVVLNLPCPVEGSSNTEQLLEIAEKFRGDGAQ
HCCCCCEECCCCEEEECCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCC
VGKKEDLEWRSWPVSQRLSHALVKGITEFIDEDTEAARQEAKRPLDVIEGALMDGMNVVG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
DLFGSGKMFLPQVVKSARVMKKAVAYLNPYIELEKVEGQSNGKILMVTVKGDVHDIGKNI
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHH
VGVVLACNGFEVFDLGVMVSVERILDAVKEHNIDIIGMSGLITPSLDEMVHNVKTFHREG
EEEEEEECCCEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCC
LTIPAIIGGATCSKIHTAVKIAPHYPHGAIYIADASRAVPMVSKLINNETRQATIDETYA
CEEEEEECCCHHHHHHHHEEECCCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHH
EYDDMRTKRLSQAKRKEIVSLEAARDNRCQHDWANYTPFTPNVLGRQVFDNYPLEDLVER
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHH
IDWTPFFRSWELHGHYPEILTDKVVGVEAQKLFADGQAMLKQIIEEKWLTAKAVIGLFPA
CCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHEECCC
NTVNYDDIELYTDESRTTVEMTTHHLRMQLERVGNDNFCLSDFVAPKDSGVADYMGGFAV
CCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCHHHHHCCEEE
TTGHGIDEHVARFEANHDDYNAIMLKCLADRLAEAFAERMHERVRKEFWGYAADEQLSNE
ECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCHH
ALIREKYKGIRPAPGYPACPDHTEKGLLWDLLKPDETIDLNITESYAMFPTAAVSGWYFA
HHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEECCCHHHCCHHHHCCEEEE
HPKSRYFGVSNIGRDQVEDYAKRKGMSIAETEKWLAPVLDYDPE
CCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]