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The map label for this gene is murB [H]

Identifier: 160873309

GI number: 160873309

Start: 227190

End: 228287

Strand: Direct

Name: murB [H]

Synonym: Sbal195_0183

Alternate gene names: 160873309

Gene position: 227190-228287 (Clockwise)

Preceding gene: 160873307

Following gene: 160873310

Centisome position: 4.25

GC content: 47.18

Gene sequence:

>1098_bases
ATGTCCTCCGCGTTAGCTGCAATCCTCGCTTTTAGCAGTTACAATGTGTTTTTGTCGTCATTGATCAAACACATGTCTCT
AGCTCATAGCCTTAAATCGTTTAATTCCTTTGGTTTAGCCCAGTCTTGCGCCGATCTTGTTGAGGCGCACTCAAAAGAAG
CTGTTCAGGCGATGTGTTTGCCACTATGGCAACAGCAATTGCCTATGTTGGTGCTTGGTGGCGGTAGCAATCTGGTCTTC
ACTGAGGACTTTAACGGTACAGTTGTCAGGGTTTTATCGAAGGGGATAAAAGTATCTGAAGACGCAGAAGCATTTTATCT
CGAGGTTGAGGCGGGTGAGAATTGGCACGAGTTAATTCAGTTTACGCTCGAGCATGGCATGTTTGGGCTGGAAAATATGG
CGTTAATTCCTGGAACGGTTGGGGCAGCACCTATCCAGAATATTGGCGCTTATGGTGTTGAACTCTGTGATGTATGTGAT
TGGGTTGAGTATCTTGATTTACCCTCAGGTGAGTTTGTGCGTATAAGCACTGCTGAGTGTCAATTTGCTTACCGTGAATC
CATTTTCAAAGACAAATTACGTAATCTTGCCGTAGTCACTGCTGTCGGACTGCGCTTAGTTAAAAGGTGGCAACCGCGTT
TGGCCTATGGCCCATTGCAATCGTTTGATCCCGCAACCGTTACAGCCCGTGAGATCTTTGAGCGTGTATGCCAAGTGCGC
AGTGAAAAGCTCCCTGATCCTGCTGTGCTCGGCAATGCAGGCAGTTTCTTTAAAAATCCTATTGTTAGCGCGGCCTGTTA
TCTAGATTTAGCACAGCGTTTTCCGACGATAGTGGGTTACGCGCAAGCGGATGCGACGGTGAAATTGGCGGCAGGTTGGT
TGATTGAACAAGCGGGATTGAAAGGTTTTGTGCTTGGTAATGCTGCTGTGCATGACAAACAAGCTTTGGTATTAGTGAAT
CGAGGCGGGGCAACGGGGCGCGATATTTGTCGCTTAGCGCTGCATGTTATTGCGCAAGTACAGGATAAATTTGGTGTTGT
GCTAGAAGCGGAACCTAGAATCATGGGCGCTAACGGTGAAGGAGATTTGTATGTCTGA

Upstream 100 bases:

>100_bases
GCCAGCTGAATAAGCTGGCTTTTTTGCGTCTGCAATTTGTTAAGTTTAGCGTGATTTTTTCGCCTAAATGCCTACTCCAC
GATGACTATTTCATCAATAC

Downstream 100 bases:

>100_bases
TAATTGGGGAAGAAAGCGCCAGATATTAGCGTTATTGTCTAGCGGTCAATTTGTTTCAGGCGAGCAGTTAGCCACTGAAC
TTGGGATTTCGCGCGCCGCT

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MSSALAAILAFSSYNVFLSSLIKHMSLAHSLKSFNSFGLAQSCADLVEAHSKEAVQAMCLPLWQQQLPMLVLGGGSNLVF
TEDFNGTVVRVLSKGIKVSEDAEAFYLEVEAGENWHELIQFTLEHGMFGLENMALIPGTVGAAPIQNIGAYGVELCDVCD
WVEYLDLPSGEFVRISTAECQFAYRESIFKDKLRNLAVVTAVGLRLVKRWQPRLAYGPLQSFDPATVTAREIFERVCQVR
SEKLPDPAVLGNAGSFFKNPIVSAACYLDLAQRFPTIVGYAQADATVKLAAGWLIEQAGLKGFVLGNAAVHDKQALVLVN
RGGATGRDICRLALHVIAQVQDKFGVVLEAEPRIMGANGEGDLYV

Sequences:

>Translated_365_residues
MSSALAAILAFSSYNVFLSSLIKHMSLAHSLKSFNSFGLAQSCADLVEAHSKEAVQAMCLPLWQQQLPMLVLGGGSNLVF
TEDFNGTVVRVLSKGIKVSEDAEAFYLEVEAGENWHELIQFTLEHGMFGLENMALIPGTVGAAPIQNIGAYGVELCDVCD
WVEYLDLPSGEFVRISTAECQFAYRESIFKDKLRNLAVVTAVGLRLVKRWQPRLAYGPLQSFDPATVTAREIFERVCQVR
SEKLPDPAVLGNAGSFFKNPIVSAACYLDLAQRFPTIVGYAQADATVKLAAGWLIEQAGLKGFVLGNAAVHDKQALVLVN
RGGATGRDICRLALHVIAQVQDKFGVVLEAEPRIMGANGEGDLYV
>Mature_364_residues
SSALAAILAFSSYNVFLSSLIKHMSLAHSLKSFNSFGLAQSCADLVEAHSKEAVQAMCLPLWQQQLPMLVLGGGSNLVFT
EDFNGTVVRVLSKGIKVSEDAEAFYLEVEAGENWHELIQFTLEHGMFGLENMALIPGTVGAAPIQNIGAYGVELCDVCDW
VEYLDLPSGEFVRISTAECQFAYRESIFKDKLRNLAVVTAVGLRLVKRWQPRLAYGPLQSFDPATVTAREIFERVCQVRS
EKLPDPAVLGNAGSFFKNPIVSAACYLDLAQRFPTIVGYAQADATVKLAAGWLIEQAGLKGFVLGNAAVHDKQALVLVNR
GGATGRDICRLALHVIAQVQDKFGVVLEAEPRIMGANGEGDLYV

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=338, Percent_Identity=51.4792899408284, Blast_Score=352, Evalue=3e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 39617; Mature: 39486

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSALAAILAFSSYNVFLSSLIKHMSLAHSLKSFNSFGLAQSCADLVEAHSKEAVQAMCL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
PLWQQQLPMLVLGGGSNLVFTEDFNGTVVRVLSKGIKVSEDAEAFYLEVEAGENWHELIQ
HHHHHCCCEEEEECCCCEEEEECCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHH
FTLEHGMFGLENMALIPGTVGAAPIQNIGAYGVELCDVCDWVEYLDLPSGEFVRISTAEC
HHHHHCCCCCCCCEECCCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHH
QFAYRESIFKDKLRNLAVVTAVGLRLVKRWQPRLAYGPLQSFDPATVTAREIFERVCQVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
SEKLPDPAVLGNAGSFFKNPIVSAACYLDLAQRFPTIVGYAQADATVKLAAGWLIEQAGL
HHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCEEEEHHHHHHHHCCC
KGFVLGNAAVHDKQALVLVNRGGATGRDICRLALHVIAQVQDKFGVVLEAEPRIMGANGE
CEEEECCCEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCEECCCCC
GDLYV
CCCCC
>Mature Secondary Structure 
SSALAAILAFSSYNVFLSSLIKHMSLAHSLKSFNSFGLAQSCADLVEAHSKEAVQAMCL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
PLWQQQLPMLVLGGGSNLVFTEDFNGTVVRVLSKGIKVSEDAEAFYLEVEAGENWHELIQ
HHHHHCCCEEEEECCCCEEEEECCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHH
FTLEHGMFGLENMALIPGTVGAAPIQNIGAYGVELCDVCDWVEYLDLPSGEFVRISTAEC
HHHHHCCCCCCCCEECCCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHH
QFAYRESIFKDKLRNLAVVTAVGLRLVKRWQPRLAYGPLQSFDPATVTAREIFERVCQVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
SEKLPDPAVLGNAGSFFKNPIVSAACYLDLAQRFPTIVGYAQADATVKLAAGWLIEQAGL
HHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCEEEEHHHHHHHHCCC
KGFVLGNAAVHDKQALVLVNRGGATGRDICRLALHVIAQVQDKFGVVLEAEPRIMGANGE
CEEEECCCEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCEECCCCC
GDLYV
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA