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The map label for this gene is tgl

Identifier: 16080179

GI number: 16080179

Start: 3212591

End: 3213328

Strand: Direct

Name: tgl

Synonym: BSU31270

Alternate gene names: 16080179

Gene position: 3212591-3213328 (Clockwise)

Preceding gene: 16080169

Following gene: 255767711

Centisome position: 76.21

GC content: 41.87

Gene sequence:

>738_bases
ATGATTATTGTATCAGGACAATTGCTCCGTCCCCAGGATATTGAAAATTGGCAGATTGATCAAGATCTGAATCCGCTCTT
AAAAGAGATGATTGAGACGCCTGTTCAGTTTGATTATCATTCAATTGCTGAACTGATGTTTGAGCTTAAACTGCGGATGA
ATATTGTAGCAGCGGCAAAGACGCTGCACAAAAGCGGGGCGAAGTTTGCCACTTTTTTAAAAACATACGGGAATACAACG
TATTGGAGGGTTTCACCGGAGGGCGCCTTGGAGCTGAAATACAGAATGCCGCCTTCAAAAGCGATTCGGGACATTGCAGA
GAACGGCCCGTTTTATGCGTTTGAATGCGCAACCGCAATCGTTATCATTTATTACTTGGCCTTAATCGATACAATCGGAG
AAGATAAATTCAATGCCAGCTTTGACAGAATTATTTTATATGACTGGCATTATGAGAAATTGCCGATATATACGGAAACA
GGACACCACTTTTTCCTTGGAGATTGTTTGTATTTTAAGAATCCTGAATTTGATCCGCAAAAGGCGCAATGGAGAGGCGA
AAATGTGATACTACTGGGGGAAGATAAATATTTTGCCCATGGTCTTGGAATCTTAAACGGAAAGCAAATTATTGATAAGC
TGAATTCTTTTAGGAAAAAAGGAGCCTTACAGTCAGCCTACCTTCTGTCTCAGGCGACCAGACTGGATGTTCCGTCTCTT
TTCCGCATCGTCCGCTAA

Upstream 100 bases:

>100_bases
AATAAAAAATGGAAGAAGTTCTTTTTGGCTGTCTTCTGCCTTTTTAACTTTCATTGCCCAAGCTCTTTGCATATCTTATA
AAAAACAAGGGGGGCTAAAC

Downstream 100 bases:

>100_bases
AAAGCCCCATCGCCTATTTTCCGGACGATGGGGTTTCAAATGCCTTTCGTTTTCGATAGAAGGGGGCTGTGCCAAAATAT
TGGTTCGCAGCCCACTCCAT

Product: transglutaminase

Products: NA

Alternate protein names: Transglutaminase; TGase

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MIIVSGQLLRPQDIENWQIDQDLNPLLKEMIETPVQFDYHSIAELMFELKLRMNIVAAAKTLHKSGAKFATFLKTYGNTT
YWRVSPEGALELKYRMPPSKAIRDIAENGPFYAFECATAIVIIYYLALIDTIGEDKFNASFDRIILYDWHYEKLPIYTET
GHHFFLGDCLYFKNPEFDPQKAQWRGENVILLGEDKYFAHGLGILNGKQIIDKLNSFRKKGALQSAYLLSQATRLDVPSL
FRIVR

Sequences:

>Translated_245_residues
MIIVSGQLLRPQDIENWQIDQDLNPLLKEMIETPVQFDYHSIAELMFELKLRMNIVAAAKTLHKSGAKFATFLKTYGNTT
YWRVSPEGALELKYRMPPSKAIRDIAENGPFYAFECATAIVIIYYLALIDTIGEDKFNASFDRIILYDWHYEKLPIYTET
GHHFFLGDCLYFKNPEFDPQKAQWRGENVILLGEDKYFAHGLGILNGKQIIDKLNSFRKKGALQSAYLLSQATRLDVPSL
FRIVR
>Mature_245_residues
MIIVSGQLLRPQDIENWQIDQDLNPLLKEMIETPVQFDYHSIAELMFELKLRMNIVAAAKTLHKSGAKFATFLKTYGNTT
YWRVSPEGALELKYRMPPSKAIRDIAENGPFYAFECATAIVIIYYLALIDTIGEDKFNASFDRIILYDWHYEKLPIYTET
GHHFFLGDCLYFKNPEFDPQKAQWRGENVILLGEDKYFAHGLGILNGKQIIDKLNSFRKKGALQSAYLLSQATRLDVPSL
FRIVR

Specific function: Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links. In wild-type spores at 37 degrees Celsius, tgl mediates the cross- linking of gerQ in higher molecular mass forms, probably in coope

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacillus TGase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TGL_BACSU (P40746)

Other databases:

- EMBL:   Z93935
- EMBL:   AL009126
- EMBL:   L29189
- PIR:   JE0179
- RefSeq:   NP_391005.1
- ProteinModelPortal:   P40746
- EnsemblBacteria:   EBBACT00000001223
- GeneID:   937158
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU31270
- NMPDR:   fig|224308.1.peg.3130
- GenoList:   BSU31270
- GeneTree:   EBGT00050000001129
- HOGENOM:   HBG339895
- OMA:   FECATAI
- ProtClustDB:   PRK03187
- BioCyc:   BSUB:BSU31270-MONOMER
- BRENDA:   2.3.2.13
- HAMAP:   MF_00727
- InterPro:   IPR020916

Pfam domain/function: NA

EC number: =2.3.2.13

Molecular weight: Translated: 28296; Mature: 28296

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIVSGQLLRPQDIENWQIDQDLNPLLKEMIETPVQFDYHSIAELMFELKLRMNIVAAAK
CEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TLHKSGAKFATFLKTYGNTTYWRVSPEGALELKYRMPPSKAIRDIAENGPFYAFECATAI
HHHHCCCHHHHHHHHHCCCEEEEECCCCCEEEEEECCHHHHHHHHHHCCCEEEHHHHHHH
VIIYYLALIDTIGEDKFNASFDRIILYDWHYEKLPIYTETGHHFFLGDCLYFKNPEFDPQ
HHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCEEEECCCEEEEEEEEEECCCCCCCC
KAQWRGENVILLGEDKYFAHGLGILNGKQIIDKLNSFRKKGALQSAYLLSQATRLDVPSL
HHHCCCCEEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHH
FRIVR
HHHCC
>Mature Secondary Structure
MIIVSGQLLRPQDIENWQIDQDLNPLLKEMIETPVQFDYHSIAELMFELKLRMNIVAAAK
CEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TLHKSGAKFATFLKTYGNTTYWRVSPEGALELKYRMPPSKAIRDIAENGPFYAFECATAI
HHHHCCCHHHHHHHHHCCCEEEEECCCCCEEEEEECCHHHHHHHHHHCCCEEEHHHHHHH
VIIYYLALIDTIGEDKFNASFDRIILYDWHYEKLPIYTETGHHFFLGDCLYFKNPEFDPQ
HHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCEEEECCCEEEEEEEEEECCCCCCCC
KAQWRGENVILLGEDKYFAHGLGILNGKQIIDKLNSFRKKGALQSAYLLSQATRLDVPSL
HHHCCCCEEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHH
FRIVR
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377; 8188684; 9692191