Click here to switch to the map view.

The map label for this gene is pdhS [H]

Identifier: 159900990

GI number: 159900990

Start: 5728801

End: 5730546

Strand: Direct

Name: pdhS [H]

Synonym: Haur_4477

Alternate gene names: 159900990

Gene position: 5728801-5730546 (Clockwise)

Preceding gene: 159900989

Following gene: 159900991

Centisome position: 90.27

GC content: 49.77

Gene sequence:

>1746_bases
ATGAGCGACCAACCCGCAGCTTCAGATTCAGCCGCATCAACCAATCTTCAGACAGCCCTCAACGCTGAGGTGGCGTTTGG
TCTTCGCCCAACCGTAACAGGATTGGGTTTTTTATATTTGTTATTTAGTATTGCCCATGCGTTGGTTTTGCCCAGCCCAA
TTAAACTACCAATGGTCATCGTAGCGCTCAGTAGTGTCATTTTTTTTGGATTTTGGTGGTGGCGCTTGCAAAGCTGGCGG
CCAGCCCCCGAGCTGACCCATCCGCTGGCCACGCTCTTTATTGTGGTTGGCGGCTTCAATAGCGTTTTGCATATCTGGCT
GAGCGGCGAGATTCACCAAAGCACCAATATTGCCTTTATTTTAATTGGCACTGGCTGTTTGTTGCTTTCTTGGAATTGGT
TCATCGTAGCGAGTGGGGCTATTTTGCTGGCGTGGATTGCGGCGATCATTTCATTGCCAACCTCACCGTTGACCATGCAT
TTTATTTTTATGGTGGTTAGTGCCACGATTGCCGCTGCCACAATTCAAGGCATTCGTTTGCGCACGGTCAAGGGCTTGAT
CAAATTGCGCTTGCAAGAAAGCACCTACAAACAAGAGCTACAAGAGGCCTTAATCCAAATCAAAATGAGTGAAGAGCGTT
TTCGCGCCTTGGCCGAAGCAACCTCCGAAGGGGTGGTATTGCAAGATGAAGGCGTGGTGATGGATGCCAACGAACGCTTT
GGCGAGATGTTTGGCTATCATCGTGATGAAATTCTCGGCCACTCGTTACGCGAATTTGTCGAGCCACAATCGCTGCAACG
GGCAATGCAAAAATATAAAGATGGTGCGCCCTACGAAGTTACCGCACTGCGCAAAGATGGCAGCACCTTTATCGCCTTGG
TGTTGGGCACCAATTTGCCCTATAGCAATCGGGTGGTGCGGGTTGCGGCGGTGCGCGATATTACTGAGCAGCGCCATTTT
GAAAATTTATTGCTGACTGCCAAAGATGATGCTGAGGCCGCCAACCGCGCCAAAAGCACTTTCCTTTCAACTGTCAGCCA
CGAATTACGCACGCCACTGAATGCGATTGTTGGCTATAGCGAAATGATCTACGAGGATTTGATCGATCGCAGCATGCCTG
AGTTGGCCATGGATATGACCCGCATTCGTAGCGCTAGCGACCGCTTGTTGAGCTTGATCGATGGCGTTCTGACGATTACC
GATCTTGATGCGGAAGTTGTGCGTTTGGAGTATGAAACGATCGATTTGGCGCTGGCGATTGGCAGCATCAGCGACCAATT
GCAAGCCAAAGCCCAAGATAACAAAAATACTGTGCAATTATTGGGTAGCCAAAACTGGGGTTCGATTATCAGCGATGATC
ATAAATTGCGCATGATTATTTACCATCTGCTGGATAATGCAATTAAATTCACCCACGCAGGCTTAATTAGCATCTCGGTG
CAACGCTTGCAACACGCTGCTGGCGGTTGGCTCGAAATTGCAATTCGCGATACGGGGATTGGCATTGCCCATGAGCAATT
TGAACGGATTTTTGAGCCATTTGTTCAAGCCGATTCCTCGGCCACTCGCCAATATGAAGGTACCGGTTTGGGCTTGGCCG
TGAGCATGCGGCTGGCTCGTGCTTTGGGTGGCACGATCGAGCTTGATAGCCGCTTAGGGATTGGCTCAACGTTTACTCTG
CATATGCCCGAACATCCCACCAAACCCAATGTGCCTTCACCTCAAATGTCACACGCGAACGTATAG

Upstream 100 bases:

>100_bases
ATGCCGTGAAGCGTAAGGATGCTCGTAAGGTTCAAGCTTTAGGCTGCTTGTTAATGGGCAATTCAGATTAAAGCCCATTC
AGCAATTTTAGAGAATAGCT

Downstream 100 bases:

>100_bases
GGTTGGGATATATAGTGCGCACAATCCTCGTTTAATTAAACCTTCAAGCTATGGGCTAAATCAACATACGTTGAGTTTTC
ACTATACCAATATTTCCTAA

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 581; Mature: 580

Protein sequence:

>581_residues
MSDQPAASDSAASTNLQTALNAEVAFGLRPTVTGLGFLYLLFSIAHALVLPSPIKLPMVIVALSSVIFFGFWWWRLQSWR
PAPELTHPLATLFIVVGGFNSVLHIWLSGEIHQSTNIAFILIGTGCLLLSWNWFIVASGAILLAWIAAIISLPTSPLTMH
FIFMVVSATIAAATIQGIRLRTVKGLIKLRLQESTYKQELQEALIQIKMSEERFRALAEATSEGVVLQDEGVVMDANERF
GEMFGYHRDEILGHSLREFVEPQSLQRAMQKYKDGAPYEVTALRKDGSTFIALVLGTNLPYSNRVVRVAAVRDITEQRHF
ENLLLTAKDDAEAANRAKSTFLSTVSHELRTPLNAIVGYSEMIYEDLIDRSMPELAMDMTRIRSASDRLLSLIDGVLTIT
DLDAEVVRLEYETIDLALAIGSISDQLQAKAQDNKNTVQLLGSQNWGSIISDDHKLRMIIYHLLDNAIKFTHAGLISISV
QRLQHAAGGWLEIAIRDTGIGIAHEQFERIFEPFVQADSSATRQYEGTGLGLAVSMRLARALGGTIELDSRLGIGSTFTL
HMPEHPTKPNVPSPQMSHANV

Sequences:

>Translated_581_residues
MSDQPAASDSAASTNLQTALNAEVAFGLRPTVTGLGFLYLLFSIAHALVLPSPIKLPMVIVALSSVIFFGFWWWRLQSWR
PAPELTHPLATLFIVVGGFNSVLHIWLSGEIHQSTNIAFILIGTGCLLLSWNWFIVASGAILLAWIAAIISLPTSPLTMH
FIFMVVSATIAAATIQGIRLRTVKGLIKLRLQESTYKQELQEALIQIKMSEERFRALAEATSEGVVLQDEGVVMDANERF
GEMFGYHRDEILGHSLREFVEPQSLQRAMQKYKDGAPYEVTALRKDGSTFIALVLGTNLPYSNRVVRVAAVRDITEQRHF
ENLLLTAKDDAEAANRAKSTFLSTVSHELRTPLNAIVGYSEMIYEDLIDRSMPELAMDMTRIRSASDRLLSLIDGVLTIT
DLDAEVVRLEYETIDLALAIGSISDQLQAKAQDNKNTVQLLGSQNWGSIISDDHKLRMIIYHLLDNAIKFTHAGLISISV
QRLQHAAGGWLEIAIRDTGIGIAHEQFERIFEPFVQADSSATRQYEGTGLGLAVSMRLARALGGTIELDSRLGIGSTFTL
HMPEHPTKPNVPSPQMSHANV
>Mature_580_residues
SDQPAASDSAASTNLQTALNAEVAFGLRPTVTGLGFLYLLFSIAHALVLPSPIKLPMVIVALSSVIFFGFWWWRLQSWRP
APELTHPLATLFIVVGGFNSVLHIWLSGEIHQSTNIAFILIGTGCLLLSWNWFIVASGAILLAWIAAIISLPTSPLTMHF
IFMVVSATIAAATIQGIRLRTVKGLIKLRLQESTYKQELQEALIQIKMSEERFRALAEATSEGVVLQDEGVVMDANERFG
EMFGYHRDEILGHSLREFVEPQSLQRAMQKYKDGAPYEVTALRKDGSTFIALVLGTNLPYSNRVVRVAAVRDITEQRHFE
NLLLTAKDDAEAANRAKSTFLSTVSHELRTPLNAIVGYSEMIYEDLIDRSMPELAMDMTRIRSASDRLLSLIDGVLTITD
LDAEVVRLEYETIDLALAIGSISDQLQAKAQDNKNTVQLLGSQNWGSIISDDHKLRMIIYHLLDNAIKFTHAGLISISVQ
RLQHAAGGWLEIAIRDTGIGIAHEQFERIFEPFVQADSSATRQYEGTGLGLAVSMRLARALGGTIELDSRLGIGSTFTLH
MPEHPTKPNVPSPQMSHANV

Specific function: Functions as a polar differentiation marker. Essential protein that, by localizing in the old pole of dividing cells, controls cell division and maturation, probably through control of DivK phosphorylation status and cellular distribution, which in turn r

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm. Note=Localizes at the old pole of dividing cells. Colocalizes with divK (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=276, Percent_Identity=31.5217391304348, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI48994928, Length=275, Percent_Identity=33.0909090909091, Blast_Score=139, Evalue=7e-34,
Organism=Escherichia coli, GI1789149, Length=255, Percent_Identity=35.2941176470588, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1786600, Length=464, Percent_Identity=25.8620689655172, Blast_Score=126, Evalue=5e-30,
Organism=Escherichia coli, GI1788713, Length=359, Percent_Identity=27.5766016713092, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI87081816, Length=265, Percent_Identity=29.811320754717, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1787894, Length=236, Percent_Identity=30.0847457627119, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790436, Length=231, Percent_Identity=31.6017316017316, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786783, Length=229, Percent_Identity=26.2008733624454, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1786912, Length=308, Percent_Identity=25.3246753246753, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87082128, Length=228, Percent_Identity=25.4385964912281, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788393, Length=222, Percent_Identity=24.7747747747748, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790346, Length=199, Percent_Identity=25.1256281407035, Blast_Score=63, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=78, Percent_Identity=46.1538461538462, Blast_Score=81, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64155; Mature: 64024

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQPAASDSAASTNLQTALNAEVAFGLRPTVTGLGFLYLLFSIAHALVLPSPIKLPMVI
CCCCCCCCCCCCCCCHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
VALSSVIFFGFWWWRLQSWRPAPELTHPLATLFIVVGGFNSVLHIWLSGEIHQSTNIAFI
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCEEECCCCEEEE
LIGTGCLLLSWNWFIVASGAILLAWIAAIISLPTSPLTMHFIFMVVSATIAAATIQGIRL
EEECCEEEEECCHHEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHH
RTVKGLIKLRLQESTYKQELQEALIQIKMSEERFRALAEATSEGVVLQDEGVVMDANERF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEECCCEEEECHHHH
GEMFGYHRDEILGHSLREFVEPQSLQRAMQKYKDGAPYEVTALRKDGSTFIALVLGTNLP
HHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEEECCCC
YSNRVVRVAAVRDITEQRHFENLLLTAKDDAEAANRAKSTFLSTVSHELRTPLNAIVGYS
CCCCEEEEHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
EMIYEDLIDRSMPELAMDMTRIRSASDRLLSLIDGVLTITDLDAEVVRLEYETIDLALAI
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEHHEEEEEEE
GSISDQLQAKAQDNKNTVQLLGSQNWGSIISDDHKLRMIIYHLLDNAIKFTHAGLISISV
CCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLQHAAGGWLEIAIRDTGIGIAHEQFERIFEPFVQADSSATRQYEGTGLGLAVSMRLAR
HHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHH
ALGGTIELDSRLGIGSTFTLHMPEHPTKPNVPSPQMSHANV
HCCCCEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDQPAASDSAASTNLQTALNAEVAFGLRPTVTGLGFLYLLFSIAHALVLPSPIKLPMVI
CCCCCCCCCCCCCCHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
VALSSVIFFGFWWWRLQSWRPAPELTHPLATLFIVVGGFNSVLHIWLSGEIHQSTNIAFI
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCEEECCCCEEEE
LIGTGCLLLSWNWFIVASGAILLAWIAAIISLPTSPLTMHFIFMVVSATIAAATIQGIRL
EEECCEEEEECCHHEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHH
RTVKGLIKLRLQESTYKQELQEALIQIKMSEERFRALAEATSEGVVLQDEGVVMDANERF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEECCCEEEECHHHH
GEMFGYHRDEILGHSLREFVEPQSLQRAMQKYKDGAPYEVTALRKDGSTFIALVLGTNLP
HHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEEECCCC
YSNRVVRVAAVRDITEQRHFENLLLTAKDDAEAANRAKSTFLSTVSHELRTPLNAIVGYS
CCCCEEEEHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
EMIYEDLIDRSMPELAMDMTRIRSASDRLLSLIDGVLTITDLDAEVVRLEYETIDLALAI
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEHHEEEEEEE
GSISDQLQAKAQDNKNTVQLLGSQNWGSIISDDHKLRMIIYHLLDNAIKFTHAGLISISV
CCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLQHAAGGWLEIAIRDTGIGIAHEQFERIFEPFVQADSSATRQYEGTGLGLAVSMRLAR
HHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHH
ALGGTIELDSRLGIGSTFTLHMPEHPTKPNVPSPQMSHANV
HCCCCEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA