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The map label for this gene is aroE [H]

Identifier: 159900981

GI number: 159900981

Start: 5714360

End: 5715181

Strand: Direct

Name: aroE [H]

Synonym: Haur_4468

Alternate gene names: 159900981

Gene position: 5714360-5715181 (Clockwise)

Preceding gene: 159900980

Following gene: 159900982

Centisome position: 90.04

GC content: 55.6

Gene sequence:

>822_bases
GTGTCCCAAATAGCTGCGCTTGGTATCATTGGCGATCCAGTCGCCCATAGTCTTTCGCCTGCAATGCACAATGCTGCTTT
GCAGGCGCTTGGCATTAATCAGCAGTATGATCGCTGGCATACTCCCGCCGCTGATCTGCCAGCCCGCGTTCAAAGTTTAC
GCTCCAAGGGTATGTTGGGAGCCAATGTAACCTTGCCGCATAAAGTGGCGATTGCTGGTTTGCTTGATCGCACGGTGGCA
ATCGCCCAAGAACTTGGTGCGGTTAACACGGTTGTGCGTGAAGCTGATGGAAGTTTGACTGGCCACAACACCGATGCTCC
TGCTCTGCAAGCCTCACTGCAAGCCTACGGAGCAGATTTAGCCAAGCAACGGGCAGTGATTCTCGGCGCAGGTGGGGCGG
CTCGGGCGGCACTTTGGGCTTTACGCAATGCAGGTTGCCAACAGATTAGCCTGATCAACCGCACGCTCAGCAGTGCTCAA
GCCTTAGTTTTGCCACATGAATTGGCCTTAGCCGCTGATGATCCGCGAGTGGCCGCACACCTTGCCGCTGCAACCTTGTT
GATCAACGTCACGTCGTTGGGCTGGAAAGATACTGATCCTGCGCCGCTGGATTTGGCTCTGTTGCATGCAGGCTTGATGG
TATACGATACGGTTTATCGCCGAACGCCATTGCTGCGAGCGGCGGCGGCTTGTGGGGCGGCCCACTACGATGGCCTTGAT
ATGTTGGTGCGTCAGGCCGGTTTGGCGTTTAGTTTGTGGTTTAAGCAGCCTGCACCGCTTGAAATAATGCGAGCAGCAGC
CCTAGCGGCTCTACAAGGATAA

Upstream 100 bases:

>100_bases
CCTATTTTGTGACCAAGTGTGTGGCTGCTGGCGAACGCCCAACCCACAACTTTACCAACGACTATAGCGAATTTTTGCAA
TTTCAAGAAGAGTTTTTGGC

Downstream 100 bases:

>100_bases
TCAGCCTATGTTGCCAGCAATTCTGCTTGTGGTTGGAATCGCAATTGGTTTTGGCCTCAACCCATGGATCACCCAGCTCG
CCACTGATCCCAAAGCGGCT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MSQIAALGIIGDPVAHSLSPAMHNAALQALGINQQYDRWHTPAADLPARVQSLRSKGMLGANVTLPHKVAIAGLLDRTVA
IAQELGAVNTVVREADGSLTGHNTDAPALQASLQAYGADLAKQRAVILGAGGAARAALWALRNAGCQQISLINRTLSSAQ
ALVLPHELALAADDPRVAAHLAAATLLINVTSLGWKDTDPAPLDLALLHAGLMVYDTVYRRTPLLRAAAACGAAHYDGLD
MLVRQAGLAFSLWFKQPAPLEIMRAAALAALQG

Sequences:

>Translated_273_residues
MSQIAALGIIGDPVAHSLSPAMHNAALQALGINQQYDRWHTPAADLPARVQSLRSKGMLGANVTLPHKVAIAGLLDRTVA
IAQELGAVNTVVREADGSLTGHNTDAPALQASLQAYGADLAKQRAVILGAGGAARAALWALRNAGCQQISLINRTLSSAQ
ALVLPHELALAADDPRVAAHLAAATLLINVTSLGWKDTDPAPLDLALLHAGLMVYDTVYRRTPLLRAAAACGAAHYDGLD
MLVRQAGLAFSLWFKQPAPLEIMRAAALAALQG
>Mature_272_residues
SQIAALGIIGDPVAHSLSPAMHNAALQALGINQQYDRWHTPAADLPARVQSLRSKGMLGANVTLPHKVAIAGLLDRTVAI
AQELGAVNTVVREADGSLTGHNTDAPALQASLQAYGADLAKQRAVILGAGGAARAALWALRNAGCQQISLINRTLSSAQA
LVLPHELALAADDPRVAAHLAAATLLINVTSLGWKDTDPAPLDLALLHAGLMVYDTVYRRTPLLRAAAACGAAHYDGLDM
LVRQAGLAFSLWFKQPAPLEIMRAAALAALQG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=273, Percent_Identity=32.6007326007326, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789675, Length=253, Percent_Identity=36.3636363636364, Blast_Score=122, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6320332, Length=166, Percent_Identity=35.5421686746988, Blast_Score=105, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 28431; Mature: 28300

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQIAALGIIGDPVAHSLSPAMHNAALQALGINQQYDRWHTPAADLPARVQSLRSKGMLG
CCCCEEECCCCCHHHHHCCHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHCCCCC
ANVTLPHKVAIAGLLDRTVAIAQELGAVNTVVREADGSLTGHNTDAPALQASLQAYGADL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
AKQRAVILGAGGAARAALWALRNAGCQQISLINRTLSSAQALVLPHELALAADDPRVAAH
HHCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEECHHHEEECCCCHHHHH
LAAATLLINVTSLGWKDTDPAPLDLALLHAGLMVYDTVYRRTPLLRAAAACGAAHYDGLD
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHCCHHH
MLVRQAGLAFSLWFKQPAPLEIMRAAALAALQG
HHHHHHCCEEEEECCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQIAALGIIGDPVAHSLSPAMHNAALQALGINQQYDRWHTPAADLPARVQSLRSKGMLG
CCCEEECCCCCHHHHHCCHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHCCCCC
ANVTLPHKVAIAGLLDRTVAIAQELGAVNTVVREADGSLTGHNTDAPALQASLQAYGADL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
AKQRAVILGAGGAARAALWALRNAGCQQISLINRTLSSAQALVLPHELALAADDPRVAAH
HHCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEECHHHEEECCCCHHHHH
LAAATLLINVTSLGWKDTDPAPLDLALLHAGLMVYDTVYRRTPLLRAAAACGAAHYDGLD
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHCCHHH
MLVRQAGLAFSLWFKQPAPLEIMRAAALAALQG
HHHHHHCCEEEEECCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]