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The map label for this gene is ytcB [H]

Identifier: 159900946

GI number: 159900946

Start: 5673137

End: 5674093

Strand: Direct

Name: ytcB [H]

Synonym: Haur_4433

Alternate gene names: 159900946

Gene position: 5673137-5674093 (Clockwise)

Preceding gene: 159900945

Following gene: 159900947

Centisome position: 89.39

GC content: 52.56

Gene sequence:

>957_bases
ATGCGCGTGTTGATCACGGGAGCAGCAGGGTTTTTAGGCTCGCACTTGTGTGAGCGGTTTCTGTCCGAAGGTCACTCGGT
TGTTGGGATGGATAATTTCATCACTGGCAACCCCGAAAATATTGCCCATTTAGTTGGCCGCGAAGGCTTTCAATTCATTC
GCCACGATGTGACCAACTATATTTTCTTGCCTGGCCCGCTCGATGCAGTCTTGCACTTTGCCTCGCCAGCCTCGCCAATC
GATTATCTTGAACTGCCGATTCAAACGCTCAAGGTTGGGGCTTTGGGAACCCACAATGCCCTCGGTTTGGCCAAAGCCAA
AGGTGCCCGCTTCTTGATCGCCTCAACCTCAGAGGTTTATGGCGATCCGCAAGTTCACCCTCAACCCGAAACCTATTGGG
GCCACGTCAACCCAATCGGGCCACGCGGGGTTTACGATGAAGCCAAACGCTTTGCCGAAGCCATGACCATGGCCTACCAC
ACCTACCACGGCGTGCAAACGCGGATTGTGCGGATTTTCAACACCTATGGTCCACGTATGCGCTTGGCTGATGGTCGGGT
TGTGCCTAACTTTATTCAACAAGCGCTGCGCGGCGAGGCATTAACGCTCTACGGCGATGGCTTGCAAACCCGCTCGTTCC
AATTCGTTGGCGATTTGGTCGAAGGCGTGTATCGTTTGTTGCTCTCCGATGAGGTTGAGCCGGTTAATATTGGCAATCCC
CACGAGTTCACGATGCGTGAGTTTGCCGAAATCGTCAATGCCATGACTGGCAATCCCGCTGGTACGGTGATTAAGCCCGA
ACTACGCATCAAAGACGACCCCCAAAATCGCCAGCCTGATATTAGCAAAGCCAAACGGGTATTGAATTGGGAGCCACAAG
TCACTTTGCAAGCAGGCTTGGAACAAACGATTCCATGGTTTGCTGAGCAATTGCGCCAACGTGGCGAAATTAAATAA

Upstream 100 bases:

>100_bases
TCGTCGAAGCAACGCTTAGCGATAATTAATTTTCAGCCAAGCAATCTGCGTTTAGAATAGGGCGACTTCTGCGCCGATAT
TCTGTTTGAAGGAGTTCACG

Downstream 100 bases:

>100_bases
GTCCAACGTAGGCTATTCCAAGCTCCTGAGCATCGGCGTGGATGGCTCGGGCTTTTGGTATGCGATCGATTTGCCGCATT
TGCAACGAAGAAGCCGAGGA

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MRVLITGAAGFLGSHLCERFLSEGHSVVGMDNFITGNPENIAHLVGREGFQFIRHDVTNYIFLPGPLDAVLHFASPASPI
DYLELPIQTLKVGALGTHNALGLAKAKGARFLIASTSEVYGDPQVHPQPETYWGHVNPIGPRGVYDEAKRFAEAMTMAYH
TYHGVQTRIVRIFNTYGPRMRLADGRVVPNFIQQALRGEALTLYGDGLQTRSFQFVGDLVEGVYRLLLSDEVEPVNIGNP
HEFTMREFAEIVNAMTGNPAGTVIKPELRIKDDPQNRQPDISKAKRVLNWEPQVTLQAGLEQTIPWFAEQLRQRGEIK

Sequences:

>Translated_318_residues
MRVLITGAAGFLGSHLCERFLSEGHSVVGMDNFITGNPENIAHLVGREGFQFIRHDVTNYIFLPGPLDAVLHFASPASPI
DYLELPIQTLKVGALGTHNALGLAKAKGARFLIASTSEVYGDPQVHPQPETYWGHVNPIGPRGVYDEAKRFAEAMTMAYH
TYHGVQTRIVRIFNTYGPRMRLADGRVVPNFIQQALRGEALTLYGDGLQTRSFQFVGDLVEGVYRLLLSDEVEPVNIGNP
HEFTMREFAEIVNAMTGNPAGTVIKPELRIKDDPQNRQPDISKAKRVLNWEPQVTLQAGLEQTIPWFAEQLRQRGEIK
>Mature_318_residues
MRVLITGAAGFLGSHLCERFLSEGHSVVGMDNFITGNPENIAHLVGREGFQFIRHDVTNYIFLPGPLDAVLHFASPASPI
DYLELPIQTLKVGALGTHNALGLAKAKGARFLIASTSEVYGDPQVHPQPETYWGHVNPIGPRGVYDEAKRFAEAMTMAYH
TYHGVQTRIVRIFNTYGPRMRLADGRVVPNFIQQALRGEALTLYGDGLQTRSFQFVGDLVEGVYRLLLSDEVEPVNIGNP
HEFTMREFAEIVNAMTGNPAGTVIKPELRIKDDPQNRQPDISKAKRVLNWEPQVTLQAGLEQTIPWFAEQLRQRGEIK

Specific function: Unknown

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=310, Percent_Identity=54.5161290322581, Blast_Score=354, Evalue=6e-98,
Organism=Homo sapiens, GI7657641, Length=331, Percent_Identity=25.9818731117825, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI56237023, Length=342, Percent_Identity=27.1929824561404, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI56118217, Length=342, Percent_Identity=27.1929824561404, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI189083684, Length=342, Percent_Identity=27.1929824561404, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4507709, Length=327, Percent_Identity=24.1590214067278, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1788589, Length=337, Percent_Identity=27.893175074184, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI48994969, Length=334, Percent_Identity=27.5449101796407, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788353, Length=350, Percent_Identity=25.4285714285714, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=27.0833333333333, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1788366, Length=361, Percent_Identity=26.3157894736842, Blast_Score=78, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17539532, Length=310, Percent_Identity=50.3225806451613, Blast_Score=336, Evalue=8e-93,
Organism=Caenorhabditis elegans, GI115532424, Length=340, Percent_Identity=27.6470588235294, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17568069, Length=331, Percent_Identity=26.8882175226586, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17507723, Length=330, Percent_Identity=26.0606060606061, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI133901788, Length=330, Percent_Identity=26.3636363636364, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17539422, Length=330, Percent_Identity=26.3636363636364, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI133901786, Length=330, Percent_Identity=26.3636363636364, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI133901790, Length=330, Percent_Identity=26.3636363636364, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17539424, Length=330, Percent_Identity=26.3636363636364, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=348, Percent_Identity=23.8505747126437, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71982038, Length=350, Percent_Identity=23.7142857142857, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=361, Percent_Identity=24.6537396121884, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356223, Length=310, Percent_Identity=55.1612903225806, Blast_Score=368, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: NA

Molecular weight: Translated: 35412; Mature: 35412

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLITGAAGFLGSHLCERFLSEGHSVVGMDNFITGNPENIAHLVGREGFQFIRHDVTNY
CEEEEECCHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCE
IFLPGPLDAVLHFASPASPIDYLELPIQTLKVGALGTHNALGLAKAKGARFLIASTSEVY
EEECCHHHHHHHHCCCCCCHHHHHCCHHHHEECCCCCCCCCCHHHCCCCEEEEEECHHHC
GDPQVHPQPETYWGHVNPIGPRGVYDEAKRFAEAMTMAYHTYHGVQTRIVRIFNTYGPRM
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
RLADGRVVPNFIQQALRGEALTLYGDGLQTRSFQFVGDLVEGVYRLLLSDEVEPVNIGNP
EECCCCCCHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
HEFTMREFAEIVNAMTGNPAGTVIKPELRIKDDPQNRQPDISKAKRVLNWEPQVTLQAGL
CHHHHHHHHHHHHHHCCCCCCCEECCCEEECCCCCCCCCCHHHHHHHHCCCCCCHHHHCH
EQTIPWFAEQLRQRGEIK
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRVLITGAAGFLGSHLCERFLSEGHSVVGMDNFITGNPENIAHLVGREGFQFIRHDVTNY
CEEEEECCHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCE
IFLPGPLDAVLHFASPASPIDYLELPIQTLKVGALGTHNALGLAKAKGARFLIASTSEVY
EEECCHHHHHHHHCCCCCCHHHHHCCHHHHEECCCCCCCCCCHHHCCCCEEEEEECHHHC
GDPQVHPQPETYWGHVNPIGPRGVYDEAKRFAEAMTMAYHTYHGVQTRIVRIFNTYGPRM
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
RLADGRVVPNFIQQALRGEALTLYGDGLQTRSFQFVGDLVEGVYRLLLSDEVEPVNIGNP
EECCCCCCHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
HEFTMREFAEIVNAMTGNPAGTVIKPELRIKDDPQNRQPDISKAKRVLNWEPQVTLQAGL
CHHHHHHHHHHHHHHCCCCCCCEECCCEEECCCCCCCCCCHHHHHHHHCCCCCCHHHHCH
EQTIPWFAEQLRQRGEIK
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]