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The map label for this gene is yrkH [H]

Identifier: 159899802

GI number: 159899802

Start: 4150327

End: 4151436

Strand: Direct

Name: yrkH [H]

Synonym: Haur_3284

Alternate gene names: 159899802

Gene position: 4150327-4151436 (Clockwise)

Preceding gene: 159899801

Following gene: 159899803

Centisome position: 65.39

GC content: 52.43

Gene sequence:

>1110_bases
ATGATTCAAACAATTGATGTTACAACCTTGCAAACTTGGCTGAGCCAAGGCCAATCGGTAAGCGTGCTCGATGTTCGGCC
TGAGGCCGATTGGCAGGAATGGTCAATTCCGCAAAGTGTCCATGCTGAGGCTTATCACGATTTAAAGGCTGGTCAACTGG
CTCCAGCCCTGCAAAACCTCAATCTGCCCCAAAACCAGCCAATTGTGACGGTTTGTGGAATGGGCAAGATGAGCCTGGTT
GCCGCCGAACAACTCCAAGCGCGAGGCTATCAGGTCTATTCGTTGGCTGGCGGGATGCAAGCATGGAGCCTAGCTTGGAA
TAGTGCGCAACTACCGACGTTAGCAAATGGCACTGAAATTATCCAAATTCGGCGGACAGGCAAAGGTTGTCTTTCATACC
TAATTGGTTCGCAAGGCCAAGCGTTGGTAATCGATGCCAGCCTTGATCCAGCGGTTTATCTGCAACTAGCGCAAGCGCGT
GGCTGGCAGCTTCAGGCCGTTTTGGATACGCATATTCACGCCGATCATCTTTCACGTTCACGTCAATTGGCCGAATTGAG
TGGTGCAACCTTTTACCTGCCCGCCAATCAACGCAACAGTGGCGTATACCAGCCAATCAGCGCCAATATGCAAATTCAAC
TTGGAGCTGCCACAATTCAGGCCTTAGCTACGCCTGGCCATACTTGGGAAAGCATGAGCTATTTGCTCGATGGTAGTCAT
CTTTTTAGTGGCGACACGCTGTTTTTGGCGGCGGTTGGGCGGCCCGACCTCGAAGCCCAAGCCGCTGAAGCGCAACAACG
AGCCAGTGCCCTATACCAAAGCTTGCAAACAATTTTGGCGCTTGATCCTGCAAGCATTATTTTGCCAGGCCACACCAGCA
AACCAGTTGCCTTTGATGGTGTGCCAATTATGGCGAGTTTGGCTGAGGTGCAGACAGCAACACCTCGTTTAGCCCAAACT
GAAGCTGAATTTGTGGCGGGATTAACCGCTGTGCGCCCAGCAACGCCGCCGAATCATCAAACGATTGTCCAGTTGAATCA
GGCTGGAGCCGCGCTACCCGACGATCTCATCACCCTCGAAGCTGGAGCCAACCGCTGTGCTATCGCCTAA

Upstream 100 bases:

>100_bases
TGGCAACGCTGAGCCAACGTGGTTTTGAAGTCTATCGGCTCGATGGTGGAATTGTCGAATGGCAAGCTCATGGTTTTGCC
TTAGCTCAGGAAACAGCCAA

Downstream 100 bases:

>100_bases
AGCTCATCCTGCGATCAACCAAACTGGCTTACGCGCCAATCTTGGTCAATTTAGCCTGCTGATGCTGATCAACGCTATGG
TCGGCGGCATGATTGGTCTA

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MIQTIDVTTLQTWLSQGQSVSVLDVRPEADWQEWSIPQSVHAEAYHDLKAGQLAPALQNLNLPQNQPIVTVCGMGKMSLV
AAEQLQARGYQVYSLAGGMQAWSLAWNSAQLPTLANGTEIIQIRRTGKGCLSYLIGSQGQALVIDASLDPAVYLQLAQAR
GWQLQAVLDTHIHADHLSRSRQLAELSGATFYLPANQRNSGVYQPISANMQIQLGAATIQALATPGHTWESMSYLLDGSH
LFSGDTLFLAAVGRPDLEAQAAEAQQRASALYQSLQTILALDPASIILPGHTSKPVAFDGVPIMASLAEVQTATPRLAQT
EAEFVAGLTAVRPATPPNHQTIVQLNQAGAALPDDLITLEAGANRCAIA

Sequences:

>Translated_369_residues
MIQTIDVTTLQTWLSQGQSVSVLDVRPEADWQEWSIPQSVHAEAYHDLKAGQLAPALQNLNLPQNQPIVTVCGMGKMSLV
AAEQLQARGYQVYSLAGGMQAWSLAWNSAQLPTLANGTEIIQIRRTGKGCLSYLIGSQGQALVIDASLDPAVYLQLAQAR
GWQLQAVLDTHIHADHLSRSRQLAELSGATFYLPANQRNSGVYQPISANMQIQLGAATIQALATPGHTWESMSYLLDGSH
LFSGDTLFLAAVGRPDLEAQAAEAQQRASALYQSLQTILALDPASIILPGHTSKPVAFDGVPIMASLAEVQTATPRLAQT
EAEFVAGLTAVRPATPPNHQTIVQLNQAGAALPDDLITLEAGANRCAIA
>Mature_369_residues
MIQTIDVTTLQTWLSQGQSVSVLDVRPEADWQEWSIPQSVHAEAYHDLKAGQLAPALQNLNLPQNQPIVTVCGMGKMSLV
AAEQLQARGYQVYSLAGGMQAWSLAWNSAQLPTLANGTEIIQIRRTGKGCLSYLIGSQGQALVIDASLDPAVYLQLAQAR
GWQLQAVLDTHIHADHLSRSRQLAELSGATFYLPANQRNSGVYQPISANMQIQLGAATIQALATPGHTWESMSYLLDGSH
LFSGDTLFLAAVGRPDLEAQAAEAQQRASALYQSLQTILALDPASIILPGHTSKPVAFDGVPIMASLAEVQTATPRLAQT
EAEFVAGLTAVRPATPPNHQTIVQLNQAGAALPDDLITLEAGANRCAIA

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI116642887, Length=271, Percent_Identity=29.1512915129151, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI21703352, Length=223, Percent_Identity=31.390134529148, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI46361987, Length=158, Percent_Identity=32.9113924050633, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI14150041, Length=158, Percent_Identity=32.9113924050633, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI221330176, Length=199, Percent_Identity=31.1557788944724, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR001763 [H]

Pfam domain/function: PF00753 Lactamase_B; PF00581 Rhodanese [H]

EC number: NA

Molecular weight: Translated: 39379; Mature: 39379

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQTIDVTTLQTWLSQGQSVSVLDVRPEADWQEWSIPQSVHAEAYHDLKAGQLAPALQNL
CCEEEEHHHHHHHHHCCCEEEEEEECCCCCCHHCCCCHHHHHHHHHHCCCCHHHHHHHHC
NLPQNQPIVTVCGMGKMSLVAAEQLQARGYQVYSLAGGMQAWSLAWNSAQLPTLANGTEI
CCCCCCCEEEEECCCCHHHHHHHHHHHCCEEEEEECCCCEEEEEEECCCCCCEECCCCEE
IQIRRTGKGCLSYLIGSQGQALVIDASLDPAVYLQLAQARGWQLQAVLDTHIHADHLSRS
EEEEECCHHHHHHHHCCCCCEEEEECCCCHHHHHEEHHCCCCEEEEEHHHHHHHHHHHHH
RQLAELSGATFYLPANQRNSGVYQPISANMQIQLGAATIQALATPGHTWESMSYLLDGSH
HHHHHHCCCEEEEECCCCCCCCCCCCCCCEEEEECHHHHHHHCCCCCCHHHHHHHCCCCE
LFSGDTLFLAAVGRPDLEAQAAEAQQRASALYQSLQTILALDPASIILPGHTSKPVAFDG
EECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEECC
VPIMASLAEVQTATPRLAQTEAEFVAGLTAVRPATPPNHQTIVQLNQAGAALPDDLITLE
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCEEEEE
AGANRCAIA
CCCCCCCCC
>Mature Secondary Structure
MIQTIDVTTLQTWLSQGQSVSVLDVRPEADWQEWSIPQSVHAEAYHDLKAGQLAPALQNL
CCEEEEHHHHHHHHHCCCEEEEEEECCCCCCHHCCCCHHHHHHHHHHCCCCHHHHHHHHC
NLPQNQPIVTVCGMGKMSLVAAEQLQARGYQVYSLAGGMQAWSLAWNSAQLPTLANGTEI
CCCCCCCEEEEECCCCHHHHHHHHHHHCCEEEEEECCCCEEEEEEECCCCCCEECCCCEE
IQIRRTGKGCLSYLIGSQGQALVIDASLDPAVYLQLAQARGWQLQAVLDTHIHADHLSRS
EEEEECCHHHHHHHHCCCCCEEEEECCCCHHHHHEEHHCCCCEEEEEHHHHHHHHHHHHH
RQLAELSGATFYLPANQRNSGVYQPISANMQIQLGAATIQALATPGHTWESMSYLLDGSH
HHHHHHCCCEEEEECCCCCCCCCCCCCCCEEEEECHHHHHHHCCCCCCHHHHHHHCCCCE
LFSGDTLFLAAVGRPDLEAQAAEAQQRASALYQSLQTILALDPASIILPGHTSKPVAFDG
EECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEECC
VPIMASLAEVQTATPRLAQTEAEFVAGLTAVRPATPPNHQTIVQLNQAGAALPDDLITLE
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCEEEEE
AGANRCAIA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]