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The map label for this gene is mas [H]

Identifier: 159899763

GI number: 159899763

Start: 4107329

End: 4108309

Strand: Direct

Name: mas [H]

Synonym: Haur_3245

Alternate gene names: 159899763

Gene position: 4107329-4108309 (Clockwise)

Preceding gene: 159899762

Following gene: 159899764

Centisome position: 64.72

GC content: 54.03

Gene sequence:

>981_bases
ATGCAAGCAATTATATTTGAGCAGGCTGGTGATGCTGATGTGTTGCAATTGGCCGAAATCGCCGATTTGCAGCCGCAAGC
TGGCGAATTGTTGATTCGGGTGTATGCGACTGCCGTCAATCGGGCCGATATTTTGCAGCGTCGTGGTATGTATCCAGCGC
CAGCGGGAGCTTCAGAGATTTTGGGGCTAGAAATTGCCGGCGAGGTGATTGGCCATGGCGTGGGTGTTACAGCTCCAGCG
CTTGGGACGCGCGTTTGTGCCTTGTTGCCAGGCGGCGGTTATGCGCAGCAAGTGGTGATTCCGGCTGAACTAGCCATGCC
AATTCCGGCAAATTTGAGCTACGAACAAGCTGCGGCGATTCCCGAAGTGTGGATGACCGCCTACGATAATTTGTTTAATT
GGGGCCGTTTGAGTGCTGGCGAACGCTTGTTGGTGCATGGCGGCAGTTCAGGCATCGGTACAGCGGCGATTCAACTAGCG
CGTTGGCGTGGCGCTGAAGTACTGATCACTGCTGGCTCCGAGGCCAAAATTGCCCGTTGCCGCGAATTAGGGGCGTTTGC
CGGCATCAACTATCGAACTGAACACTGGCCTGAACGGGTGCAAGCACTGACTGAGCAGCAAGGTGTTGACGTGGTTTTGG
ATATGCTAGGAGCCAGTTATTTCAACGATAATTTAGCCAGTTTGCGGGTTGGCGGGCGCTTGGTGATTATTGCAACGATG
GGTGGAGCACAAACTGAGCTTGATCTACGCACATTGATGCTCAAACGCTTGACGGTTTGTGGCACAACCTTACGTGCCCG
CCCGATTGCCGCCAAAGCAGCCCTAACTCAACAAATGCTGGCCGATGTGTTGCCACGCTTTGCCGATGGTACATTTCAGC
CAGTCATTGAAGCGGTGTTTGATTTGGCTGAAGCCAGTGCTGCCCATCGCTTGCTGGAATCAAGCCAGCATGTCGGAAAA
ATTGTGCTGCGCGTAGCCTAG

Upstream 100 bases:

>100_bases
GCATATCAATTGATGATGAATCCATTCAATCATTGTTAAACATTGAAAGACCCCTCTCCCACAGCGGGCGAGGGTATTTT
TAGCATTTGATGAGGTAATT

Downstream 100 bases:

>100_bases
AAGAACATAGAGCATAGAACATAGAACATATTTTGATCCACAAAGAGCACGCAGAGCACGAAGGGCTGAAACCACGAAGA
ACACGAAGACCGCTAAGGAC

Product: quinone oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MQAIIFEQAGDADVLQLAEIADLQPQAGELLIRVYATAVNRADILQRRGMYPAPAGASEILGLEIAGEVIGHGVGVTAPA
LGTRVCALLPGGGYAQQVVIPAELAMPIPANLSYEQAAAIPEVWMTAYDNLFNWGRLSAGERLLVHGGSSGIGTAAIQLA
RWRGAEVLITAGSEAKIARCRELGAFAGINYRTEHWPERVQALTEQQGVDVVLDMLGASYFNDNLASLRVGGRLVIIATM
GGAQTELDLRTLMLKRLTVCGTTLRARPIAAKAALTQQMLADVLPRFADGTFQPVIEAVFDLAEASAAHRLLESSQHVGK
IVLRVA

Sequences:

>Translated_326_residues
MQAIIFEQAGDADVLQLAEIADLQPQAGELLIRVYATAVNRADILQRRGMYPAPAGASEILGLEIAGEVIGHGVGVTAPA
LGTRVCALLPGGGYAQQVVIPAELAMPIPANLSYEQAAAIPEVWMTAYDNLFNWGRLSAGERLLVHGGSSGIGTAAIQLA
RWRGAEVLITAGSEAKIARCRELGAFAGINYRTEHWPERVQALTEQQGVDVVLDMLGASYFNDNLASLRVGGRLVIIATM
GGAQTELDLRTLMLKRLTVCGTTLRARPIAAKAALTQQMLADVLPRFADGTFQPVIEAVFDLAEASAAHRLLESSQHVGK
IVLRVA
>Mature_326_residues
MQAIIFEQAGDADVLQLAEIADLQPQAGELLIRVYATAVNRADILQRRGMYPAPAGASEILGLEIAGEVIGHGVGVTAPA
LGTRVCALLPGGGYAQQVVIPAELAMPIPANLSYEQAAAIPEVWMTAYDNLFNWGRLSAGERLLVHGGSSGIGTAAIQLA
RWRGAEVLITAGSEAKIARCRELGAFAGINYRTEHWPERVQALTEQQGVDVVLDMLGASYFNDNLASLRVGGRLVIIATM
GGAQTELDLRTLMLKRLTVCGTTLRARPIAAKAALTQQMLADVLPRFADGTFQPVIEAVFDLAEASAAHRLLESSQHVGK
IVLRVA

Specific function: Catalyzes the elongation of N-fatty acyl-CoA with methylamalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=41.5151515151515, Blast_Score=245, Evalue=4e-65,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=41.5151515151515, Blast_Score=245, Evalue=4e-65,
Organism=Homo sapiens, GI194239674, Length=326, Percent_Identity=29.4478527607362, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI13236495, Length=326, Percent_Identity=29.4478527607362, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI41872631, Length=313, Percent_Identity=30.6709265175719, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=27.6527331189711, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI24308257, Length=342, Percent_Identity=25.1461988304094, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI28557745, Length=234, Percent_Identity=31.6239316239316, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI194239676, Length=326, Percent_Identity=27.6073619631902, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI197927207, Length=195, Percent_Identity=29.2307692307692, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI47519420, Length=358, Percent_Identity=25.1396648044693, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1790485, Length=328, Percent_Identity=31.0975609756098, Blast_Score=108, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17507255, Length=328, Percent_Identity=27.1341463414634, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI212642053, Length=317, Percent_Identity=25.8675078864353, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71987554, Length=346, Percent_Identity=26.3005780346821, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6319520, Length=332, Percent_Identity=26.2048192771084, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI221330659, Length=302, Percent_Identity=27.4834437086093, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI19920632, Length=302, Percent_Identity=27.4834437086093, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24581345, Length=271, Percent_Identity=28.4132841328413, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24581339, Length=247, Percent_Identity=34.0080971659919, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24581341, Length=247, Percent_Identity=34.0080971659919, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR013968
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00107 ADH_zinc_N; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.111 [H]

Molecular weight: Translated: 34625; Mature: 34625

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAIIFEQAGDADVLQLAEIADLQPQAGELLIRVYATAVNRADILQRRGMYPAPAGASEI
CCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
LGLEIAGEVIGHGVGVTAPALGTRVCALLPGGGYAQQVVIPAELAMPIPANLSYEQAAAI
HHHHHHHHHHHCCCCCCCCHHHHEEEEEECCCCCCEEEEEEHHHCCCCCCCCCHHHHHHH
PEVWMTAYDNLFNWGRLSAGERLLVHGGSSGIGTAAIQLARWRGAEVLITAGSEAKIARC
HHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHH
RELGAFAGINYRTEHWPERVQALTEQQGVDVVLDMLGASYFNDNLASLRVGGRLVIIATM
HHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHEEEECCEEEEEEEC
GGAQTELDLRTLMLKRLTVCGTTLRARPIAAKAALTQQMLADVLPRFADGTFQPVIEAVF
CCCCCHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
DLAEASAAHRLLESSQHVGKIVLRVA
HHHHHHHHHHHHHCCHHHHHEEEEEC
>Mature Secondary Structure
MQAIIFEQAGDADVLQLAEIADLQPQAGELLIRVYATAVNRADILQRRGMYPAPAGASEI
CCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
LGLEIAGEVIGHGVGVTAPALGTRVCALLPGGGYAQQVVIPAELAMPIPANLSYEQAAAI
HHHHHHHHHHHCCCCCCCCHHHHEEEEEECCCCCCEEEEEEHHHCCCCCCCCCHHHHHHH
PEVWMTAYDNLFNWGRLSAGERLLVHGGSSGIGTAAIQLARWRGAEVLITAGSEAKIARC
HHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHH
RELGAFAGINYRTEHWPERVQALTEQQGVDVVLDMLGASYFNDNLASLRVGGRLVIIATM
HHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHEEEECCEEEEEEEC
GGAQTELDLRTLMLKRLTVCGTTLRARPIAAKAALTQQMLADVLPRFADGTFQPVIEAVF
CCCCCHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
DLAEASAAHRLLESSQHVGKIVLRVA
HHHHHHHHHHHHHCCHHHHHEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1527058; 12788972 [H]