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The map label for this gene is prmA

Identifier: 159899628

GI number: 159899628

Start: 3922884

End: 3923849

Strand: Direct

Name: prmA

Synonym: Haur_3109

Alternate gene names: 159899628

Gene position: 3922884-3923849 (Clockwise)

Preceding gene: 159899627

Following gene: 159899629

Centisome position: 61.81

GC content: 53.0

Gene sequence:

>966_bases
ATGCAGTGGCTCGAACTGAGCGTGACCGTCGATACCGAAGCGGTCGAAAGTGTGTCGGAATTATTTGCCCAATATGGCTA
TAACGGTGGTGTGGCCGTCGAAGAGGCGATCATTCCATCACTCGACTCACCTGAATATCAAATTGATACCAATAAACCAG
TGATTGTGCGCACTTACCTGCTGGCCAACGAGCAAGCCGCCGATGCCCAAACCCAGATCGAGCGCGGTTTGTGGGTGCTG
GGAATGATGCGTCCAGTCGGCGATTTGCAGGTTAAAACCATCGCTGAGGAAGATTGGGCCAATGCTTGGAAGGAGCATTA
TCGCACCCGTCGCATCGGCCAACGCTTCGTGATTGTGCCCTCGTGGCTGGAATACGAGCCAGCCGAAAACGATGTTGTGC
TCAATCTCGACCCAGGTATGGCCTTTGGCACTGGCTTGCACCCCACCACCCAGCTCTGCCTTGAGTTGATGGAATTGATC
GAATTTAACAACACAACGGTGCTTGACCTTGGCTGTGGCTCAGGGATTTTGGCGGTTGGCGCTGCTAAACTTGGCTCACA
ACGTGTTTTGGCTTTAGATACCGACCCAATCGCGGTTGAAGCGACTGCTGAAAATGCTCGTATCAATCATGCCGAAACCT
TGGTAACTGCCTTGGAAGGTAGCTTGGGCGATGCACCCTTGGAGCATTGGCTCGGCTGGGAAGGCGCACAACTCGGCACG
CCGCAAAGTTATCGCCACCACAACGAGTTCGATGTGATTTTGGCCAATATTTTGGCCAAAGTGCATGTGGTGTTGGGCAA
TGATTACCTTGCGGCGCTCAAACCAGGCGGCGTACTGATTACTTCAGGCATTATCAACGAGCGCGAAGCTGATGTAGTAG
CCGCGTTTGACGCAGTTGGCTTAGAGCAAGTTGAACGGCGTACCCAAGGCGATTGGGTCGCTTTTACCCATCGCAAACCT
GTCTAA

Upstream 100 bases:

>100_bases
AGAGCATACTCTGAACTTTCAACTTCTGCCTTTTGACTTTTGATTTCTGACTTTTGACAAAGGTTTTGCCTTTTGACCTT
TGCCTTGAATAGGGGTTTTT

Downstream 100 bases:

>100_bases
TGAAAAATACCTATCGTTTTTTTGTGCCCGCCGAGGCGATTCAGGGCGAAACGTTGGCAGTGGCCGAGCGCGAATTGCTG
CACCAATGGAACAACGTGCT

Product: 50S ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MQWLELSVTVDTEAVESVSELFAQYGYNGGVAVEEAIIPSLDSPEYQIDTNKPVIVRTYLLANEQAADAQTQIERGLWVL
GMMRPVGDLQVKTIAEEDWANAWKEHYRTRRIGQRFVIVPSWLEYEPAENDVVLNLDPGMAFGTGLHPTTQLCLELMELI
EFNNTTVLDLGCGSGILAVGAAKLGSQRVLALDTDPIAVEATAENARINHAETLVTALEGSLGDAPLEHWLGWEGAQLGT
PQSYRHHNEFDVILANILAKVHVVLGNDYLAALKPGGVLITSGIINEREADVVAAFDAVGLEQVERRTQGDWVAFTHRKP
V

Sequences:

>Translated_321_residues
MQWLELSVTVDTEAVESVSELFAQYGYNGGVAVEEAIIPSLDSPEYQIDTNKPVIVRTYLLANEQAADAQTQIERGLWVL
GMMRPVGDLQVKTIAEEDWANAWKEHYRTRRIGQRFVIVPSWLEYEPAENDVVLNLDPGMAFGTGLHPTTQLCLELMELI
EFNNTTVLDLGCGSGILAVGAAKLGSQRVLALDTDPIAVEATAENARINHAETLVTALEGSLGDAPLEHWLGWEGAQLGT
PQSYRHHNEFDVILANILAKVHVVLGNDYLAALKPGGVLITSGIINEREADVVAAFDAVGLEQVERRTQGDWVAFTHRKP
V
>Mature_321_residues
MQWLELSVTVDTEAVESVSELFAQYGYNGGVAVEEAIIPSLDSPEYQIDTNKPVIVRTYLLANEQAADAQTQIERGLWVL
GMMRPVGDLQVKTIAEEDWANAWKEHYRTRRIGQRFVIVPSWLEYEPAENDVVLNLDPGMAFGTGLHPTTQLCLELMELI
EFNNTTVLDLGCGSGILAVGAAKLGSQRVLALDTDPIAVEATAENARINHAETLVTALEGSLGDAPLEHWLGWEGAQLGT
PQSYRHHNEFDVILANILAKVHVVLGNDYLAALKPGGVLITSGIINEREADVVAAFDAVGLEQVERRTQGDWVAFTHRKP
V

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=265, Percent_Identity=30.188679245283, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_HERA2 (A9B5V4)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001545875.1
- ProteinModelPortal:   A9B5V4
- SMR:   A9B5V4
- GeneID:   5734981
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_3109
- HOGENOM:   HBG584653
- OMA:   IELNPGM
- ProtClustDB:   CLSK974529
- BioCyc:   HAUR316274:HAUR_3109-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 35192; Mature: 35192

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQWLELSVTVDTEAVESVSELFAQYGYNGGVAVEEAIIPSLDSPEYQIDTNKPVIVRTYL
CCEEEEEEEECHHHHHHHHHHHHHHCCCCCCEEHHHHCCCCCCCCEEECCCCCEEEEEEE
LANEQAADAQTQIERGLWVLGMMRPVGDLQVKTIAEEDWANAWKEHYRTRRIGQRFVIVP
ECCCCCCCHHHHHHCCEEEEEHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCEEEEEE
SWLEYEPAENDVVLNLDPGMAFGTGLHPTTQLCLELMELIEFNNTTVLDLGCGSGILAVG
CCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHH
AAKLGSQRVLALDTDPIAVEATAENARINHAETLVTALEGSLGDAPLEHWLGWEGAQLGT
HHHCCCCEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCC
PQSYRHHNEFDVILANILAKVHVVLGNDYLAALKPGGVLITSGIINEREADVVAAFDAVG
CHHHCCCCHHHHHHHHHHHHEEEEECCCEEEEECCCCEEEEECCCCCCCCHHEEHHHHCC
LEQVERRTQGDWVAFTHRKPV
HHHHHHHCCCCEEEEECCCCC
>Mature Secondary Structure
MQWLELSVTVDTEAVESVSELFAQYGYNGGVAVEEAIIPSLDSPEYQIDTNKPVIVRTYL
CCEEEEEEEECHHHHHHHHHHHHHHCCCCCCEEHHHHCCCCCCCCEEECCCCCEEEEEEE
LANEQAADAQTQIERGLWVLGMMRPVGDLQVKTIAEEDWANAWKEHYRTRRIGQRFVIVP
ECCCCCCCHHHHHHCCEEEEEHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCEEEEEE
SWLEYEPAENDVVLNLDPGMAFGTGLHPTTQLCLELMELIEFNNTTVLDLGCGSGILAVG
CCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHH
AAKLGSQRVLALDTDPIAVEATAENARINHAETLVTALEGSLGDAPLEHWLGWEGAQLGT
HHHCCCCEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCC
PQSYRHHNEFDVILANILAKVHVVLGNDYLAALKPGGVLITSGIINEREADVVAAFDAVG
CHHHCCCCHHHHHHHHHHHHEEEEECCCEEEEECCCCEEEEECCCCCCCCHHEEHHHHCC
LEQVERRTQGDWVAFTHRKPV
HHHHHHHCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA