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The map label for this gene is lgrE [H]

Identifier: 159898409

GI number: 159898409

Start: 2273486

End: 2274238

Strand: Reverse

Name: lgrE [H]

Synonym: Haur_1885

Alternate gene names: 159898409

Gene position: 2274238-2273486 (Counterclockwise)

Preceding gene: 159898410

Following gene: 159898408

Centisome position: 35.83

GC content: 50.6

Gene sequence:

>753_bases
ATGTCAAGCCCATGGTTTATCTCGGTAAAACGTCAAACTCAGCCAGCAATTCGTCTCTTTTGTTTGCCTTTTGCAGGTGG
CACTGCTGCGACCTATCGATCATGGGCCAACTATCTTCCCGCAAGCATTGAACTCGTGCCAGTTGAACTGCCAGGCCGAG
GAATGCGTTTCAGCGAGCCATTGTTTGTGGCAAGTCAGCCACTGATCGCGGCCCTCGCCGAGGCCATGCAGCCGTATTTA
GCTCAACCGTATCTATTTTTTGGCCATAGCATGGGTGCGTTGCTCAGTTTTGAGCTAACCCGTTGGCTAGCGACCCATTA
TCAAAGCCAGCCTCAACAGCTCTTTGTTTCTGGGCATCGTGCTCCGCACCTTGCTGCCGCCGATACCACAACGCATCAAC
TTTCCGACCCTGATTTGCTGCAAAAAGTGCGGACAATTGATGGCACACCCAAGGAAGTACTTGAGCAACACGAATTAATG
CAACTCATGCTGCCAATTTTACGCGCCGATTTCACCATCTGTGATACCTACCAATTTCAACCAGCCCAACCGCTGAATGT
GGCAATTTCGGCCTTTGGTGGGTTTCAAGACCCAATGGTCAAACGCCACGATATTGCCGCATGGCGGGAACACACCACAG
CGGAGTTTCAGATGCACATGTTTCCAGGCGGCCATTTCTTTTTACAAACAGCCCAAGCGGCGTTTTTCAAAACCTTAAGC
CACGAACTCAACCAAATTCTCGTGCGGCTTTAA

Upstream 100 bases:

>100_bases
GAGCTTGAGTCTGCGGTTGCGCTGTTAACCAAGCTTGCGGCGGAAAAACAACCCCAACGTGCACACTAACGTGATCAATC
AACAAGGAGCATAATTACCC

Downstream 100 bases:

>100_bases
CTGCCTGGAGGCTTTATGAACATTGCTCAGCATCTCGAACGAGCATGCCTGTGCTTCCCCGATAAACCTGCCTTGATTTT
TGAACAAACGACGTATAGCT

Product: oleoyl-(acyl-carrier-protein) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSSPWFISVKRQTQPAIRLFCLPFAGGTAATYRSWANYLPASIELVPVELPGRGMRFSEPLFVASQPLIAALAEAMQPYL
AQPYLFFGHSMGALLSFELTRWLATHYQSQPQQLFVSGHRAPHLAAADTTTHQLSDPDLLQKVRTIDGTPKEVLEQHELM
QLMLPILRADFTICDTYQFQPAQPLNVAISAFGGFQDPMVKRHDIAAWREHTTAEFQMHMFPGGHFFLQTAQAAFFKTLS
HELNQILVRL

Sequences:

>Translated_250_residues
MSSPWFISVKRQTQPAIRLFCLPFAGGTAATYRSWANYLPASIELVPVELPGRGMRFSEPLFVASQPLIAALAEAMQPYL
AQPYLFFGHSMGALLSFELTRWLATHYQSQPQQLFVSGHRAPHLAAADTTTHQLSDPDLLQKVRTIDGTPKEVLEQHELM
QLMLPILRADFTICDTYQFQPAQPLNVAISAFGGFQDPMVKRHDIAAWREHTTAEFQMHMFPGGHFFLQTAQAAFFKTLS
HELNQILVRL
>Mature_249_residues
SSPWFISVKRQTQPAIRLFCLPFAGGTAATYRSWANYLPASIELVPVELPGRGMRFSEPLFVASQPLIAALAEAMQPYLA
QPYLFFGHSMGALLSFELTRWLATHYQSQPQQLFVSGHRAPHLAAADTTTHQLSDPDLLQKVRTIDGTPKEVLEQHELMQ
LMLPILRADFTICDTYQFQPAQPLNVAISAFGGFQDPMVKRHDIAAWREHTTAEFQMHMFPGGHFFLQTAQAAFFKTLSH
ELNQILVRL

Specific function: In the final step of gramicidin biosynthesis, reduces the pentadecapeptide-aldehyde intermediate, that is released from the terminal module of the non-ribosomal peptide synthetase LgrD, to the final product ethanolamine-containing gramicidin [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase family [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=229, Percent_Identity=29.2576419213974, Blast_Score=107, Evalue=7e-24,
Organism=Homo sapiens, GI8922871, Length=186, Percent_Identity=31.7204301075269, Blast_Score=91, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 28198; Mature: 28067

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPWFISVKRQTQPAIRLFCLPFAGGTAATYRSWANYLPASIELVPVELPGRGMRFSEP
CCCCEEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCC
LFVASQPLIAALAEAMQPYLAQPYLFFGHSMGALLSFELTRWLATHYQSQPQQLFVSGHR
CCCCCCHHHHHHHHHHHHHHCCCHHEECCCHHHHHHHHHHHHHHHHHCCCCHHEEECCCC
APHLAAADTTTHQLSDPDLLQKVRTIDGTPKEVLEQHELMQLMLPILRADFTICDTYQFQ
CCCEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
PAQPLNVAISAFGGFQDPMVKRHDIAAWREHTTAEFQMHMFPGGHFFLQTAQAAFFKTLS
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
HELNQILVRL
HHHHHHHHCC
>Mature Secondary Structure 
SSPWFISVKRQTQPAIRLFCLPFAGGTAATYRSWANYLPASIELVPVELPGRGMRFSEP
CCCEEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCC
LFVASQPLIAALAEAMQPYLAQPYLFFGHSMGALLSFELTRWLATHYQSQPQQLFVSGHR
CCCCCCHHHHHHHHHHHHHHCCCHHEECCCHHHHHHHHHHHHHHHHHCCCCHHEEECCCC
APHLAAADTTTHQLSDPDLLQKVRTIDGTPKEVLEQHELMQLMLPILRADFTICDTYQFQ
CCCEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
PAQPLNVAISAFGGFQDPMVKRHDIAAWREHTTAEFQMHMFPGGHFFLQTAQAAFFKTLS
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
HELNQILVRL
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA