BacMap

Definition	Herpetosiphon aurantiacus ATCC 23779 chromosome, complete genome.
Accession	NC_009972
Length	6,346,587

Click here to switch to the map view.

The map label for this gene is fabG [H]

Identifier: 159898182

GI number: 159898182

Start: 1925948

End: 1926691

Strand: Reverse

Name: fabG [H]

Synonym: Haur_1658

Alternate gene names: 159898182

Gene position: 1926691-1925948 (Counterclockwise)

Preceding gene: 159898184

Following gene: 159898181

Centisome position: 30.36

GC content: 51.34

Gene sequence:

>744_bases
ATGCTTAACGGGAAAGTCGCAATTGTGACAGGCGGAGCGATTGGAATTGGGGCGGCGACGGCGCAACTCTTAGCCAAACA
AGGCGCAATAGTGGTTATCGGCGATATTAATGAGCAAACTGGCTTAGCAACGGTTGAGCAGATTCGCGGCAACGCAGGCC
AAGCCTATTTTCGCCATTGCGATGTTAGCCACGAAGCCGATATCCAAGCCTTAGTGCAGTTCGCTCTCGACCAGGGCGGC
TTGGATATTATGATTAATAATGCTGGAATTGGCGGCAAGCCTGCACCTTTGCACTTAACCGAGAATCACAATTGGCAACG
GGTGTTAGACATCGACTTAACTGGCGTATTTTGGGGTCAAAAATATGCTAGCCAAGCCATGCTGGCAGGTGGCAAAGGCG
GCGCGATTGTCAATGTTGCCTCGATTGCGGGAGTGGCTGGCTCTCCCAACCTTGGGCCATATGGCGTGGCCAAAGCTGGA
GTCATTCAAATGAGCAAAACTGGCGCAATTGAACTGGCCTCTGCTGGCATTCGGATCAATGCAGTTTGCCCAGGCTGGAC
GGAAACCGCTATTTTAGATACATTCGAGCCAAGCGTTCAAGAACGGCTGATTCGCTCGATTCCGCTCAAGCGTATGGGCA
CGCCCCACGAAATCGCCGAATTAATCGTCTTTTTGGCCTCGCCAGCAGCTAGTTTTATCACTGGAGCTGAGTATATTATT
GATGGTGGGATTACCAGCATGTAG

Upstream 100 bases:

>100_bases
CCCAATGAACCATTCCATCTATGTTCTATGTTCATCCCTTTGACTTTTGCCTGCTGATTTTTGATAATAGCGCTACACCT
AGCATGTCAAGGAGGACAGG

Downstream 100 bases:

>100_bases
CTTAATTTGCGAAGAAAGAGGCCTGTGTGACTGCCTATACAATTGAACATCAGCTGGATAATGGCATCGAACGGATTATC
TATACGCCTCAAGAACAACG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MLNGKVAIVTGGAIGIGAATAQLLAKQGAIVVIGDINEQTGLATVEQIRGNAGQAYFRHCDVSHEADIQALVQFALDQGG
LDIMINNAGIGGKPAPLHLTENHNWQRVLDIDLTGVFWGQKYASQAMLAGGKGGAIVNVASIAGVAGSPNLGPYGVAKAG
VIQMSKTGAIELASAGIRINAVCPGWTETAILDTFEPSVQERLIRSIPLKRMGTPHEIAELIVFLASPAASFITGAEYII
DGGITSM

Sequences:

>Translated_247_residues
MLNGKVAIVTGGAIGIGAATAQLLAKQGAIVVIGDINEQTGLATVEQIRGNAGQAYFRHCDVSHEADIQALVQFALDQGG
LDIMINNAGIGGKPAPLHLTENHNWQRVLDIDLTGVFWGQKYASQAMLAGGKGGAIVNVASIAGVAGSPNLGPYGVAKAG
VIQMSKTGAIELASAGIRINAVCPGWTETAILDTFEPSVQERLIRSIPLKRMGTPHEIAELIVFLASPAASFITGAEYII
DGGITSM
>Mature_247_residues
MLNGKVAIVTGGAIGIGAATAQLLAKQGAIVVIGDINEQTGLATVEQIRGNAGQAYFRHCDVSHEADIQALVQFALDQGG
LDIMINNAGIGGKPAPLHLTENHNWQRVLDIDLTGVFWGQKYASQAMLAGGKGGAIVNVASIAGVAGSPNLGPYGVAKAG
VIQMSKTGAIELASAGIRINAVCPGWTETAILDTFEPSVQERLIRSIPLKRMGTPHEIAELIVFLASPAASFITGAEYII
DGGITSM

Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=36.3636363636364, Blast_Score=134, Evalue=8e-32,
Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=32.6612903225806, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI15277342, Length=255, Percent_Identity=32.156862745098, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI31542939, Length=208, Percent_Identity=34.6153846153846, Blast_Score=111, Evalue=6e-25,
Organism=Homo sapiens, GI4758504, Length=260, Percent_Identity=33.0769230769231, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=33.8842975206612, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI59889578, Length=228, Percent_Identity=32.0175438596491, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=35.9375, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=31.4741035856574, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=29.5719844357977, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI10190704, Length=253, Percent_Identity=32.8063241106719, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI4503301, Length=247, Percent_Identity=33.6032388663968, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI83715985, Length=260, Percent_Identity=31.5384615384615, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI126723191, Length=199, Percent_Identity=32.6633165829146, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI224922801, Length=177, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI210032110, Length=202, Percent_Identity=30.1980198019802, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=30.9644670050761, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI209862901, Length=228, Percent_Identity=28.5087719298246, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI19923983, Length=228, Percent_Identity=28.5087719298246, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI142976729, Length=252, Percent_Identity=26.984126984127, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI109715829, Length=237, Percent_Identity=29.1139240506329, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=25.8964143426295, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI4504505, Length=235, Percent_Identity=27.2340425531915, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI40807363, Length=260, Percent_Identity=25.3846153846154, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4504503, Length=219, Percent_Identity=28.310502283105, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI302344755, Length=122, Percent_Identity=32.7868852459016, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=33.1967213114754, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=32.5490196078431, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=33.1967213114754, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=35.0806451612903, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=30.0813008130081, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=32.2448979591837, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788459, Length=242, Percent_Identity=32.2314049586777, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=30.6122448979592, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1786812, Length=262, Percent_Identity=33.969465648855, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=33.0677290836653, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=27.4509803921569, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI2367365, Length=245, Percent_Identity=30.2040816326531, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1787526, Length=242, Percent_Identity=25.6198347107438, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=36.1788617886179, Blast_Score=147, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=34.6938775510204, Blast_Score=146, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=31.1740890688259, Blast_Score=117, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=32.8063241106719, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17531453, Length=260, Percent_Identity=33.0769230769231, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=31.6793893129771, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17562910, Length=274, Percent_Identity=32.1167883211679, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=32.0610687022901, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=32.7137546468402, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=30.7692307692308, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=32.5490196078431, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17538182, Length=232, Percent_Identity=29.7413793103448, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17560332, Length=260, Percent_Identity=32.3076923076923, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=30.1526717557252, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=30.3846153846154, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=30.1526717557252, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=31.8518518518519, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17563726, Length=258, Percent_Identity=31.0077519379845, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=271, Percent_Identity=30.2583025830258, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=30.9803921568627, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=30.2238805970149, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17536651, Length=259, Percent_Identity=30.5019305019305, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=31.1224489795918, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=271, Percent_Identity=30.6273062730627, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=28.5140562248996, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17561272, Length=252, Percent_Identity=32.1428571428571, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=35.3159851301115, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=27.2, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=30.188679245283, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17555612, Length=212, Percent_Identity=31.1320754716981, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=196, Percent_Identity=30.6122448979592, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=221, Percent_Identity=32.1266968325792, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=244, Percent_Identity=26.6393442622951, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=243, Percent_Identity=26.7489711934156, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI193207185, Length=121, Percent_Identity=37.1900826446281, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=26.8774703557312, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=203, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=203, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=251, Percent_Identity=31.0756972111554, Blast_Score=89, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6322861, Length=231, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320089, Length=202, Percent_Identity=28.2178217821782, Blast_Score=66, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=36.9477911646586, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=39.7590361445783, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI17737361, Length=260, Percent_Identity=33.0769230769231, Blast_Score=118, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=31.8548387096774, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=33.9920948616601, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=33.852140077821, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28571526, Length=255, Percent_Identity=33.7254901960784, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24644337, Length=256, Percent_Identity=33.203125, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24640492, Length=161, Percent_Identity=34.1614906832298, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281364892, Length=196, Percent_Identity=31.1224489795918, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281364494, Length=200, Percent_Identity=29, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=30.8, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI221331218, Length=253, Percent_Identity=28.4584980237154, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24665243, Length=253, Percent_Identity=28.4584980237154, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28571387, Length=210, Percent_Identity=30.4761904761905, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI221331216, Length=254, Percent_Identity=29.1338582677165, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24665247, Length=254, Percent_Identity=29.1338582677165, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24665268, Length=240, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI18859837, Length=216, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24665264, Length=196, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221510726, Length=229, Percent_Identity=27.5109170305677, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI161076371, Length=257, Percent_Identity=27.6264591439689, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24663911, Length=204, Percent_Identity=28.4313725490196, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI116007234, Length=203, Percent_Identity=31.5270935960591, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25510; Mature: 25510

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNGKVAIVTGGAIGIGAATAQLLAKQGAIVVIGDINEQTGLATVEQIRGNAGQAYFRHC
CCCCEEEEEECCCEEHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHCCCCCCEEHEEC
DVSHEADIQALVQFALDQGGLDIMINNAGIGGKPAPLHLTENHNWQRVLDIDLTGVFWGQ
CCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEECCCCEEEEEEEEEEEEECCH
KYASQAMLAGGKGGAIVNVASIAGVAGSPNLGPYGVAKAGVIQMSKTGAIELASAGIRIN
HHHHHHHCCCCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCEEEE
AVCPGWTETAILDTFEPSVQERLIRSIPLKRMGTPHEIAELIVFLASPAASFITGAEYII
EECCCCCCHHEEECCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCHHHHHCCCCEEE
DGGITSM
CCCCCCC
>Mature Secondary Structure
MLNGKVAIVTGGAIGIGAATAQLLAKQGAIVVIGDINEQTGLATVEQIRGNAGQAYFRHC
CCCCEEEEEECCCEEHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHCCCCCCEEHEEC
DVSHEADIQALVQFALDQGGLDIMINNAGIGGKPAPLHLTENHNWQRVLDIDLTGVFWGQ
CCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEECCCCEEEEEEEEEEEEECCH
KYASQAMLAGGKGGAIVNVASIAGVAGSPNLGPYGVAKAGVIQMSKTGAIELASAGIRIN
HHHHHHHCCCCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCEEEE
AVCPGWTETAILDTFEPSVQERLIRSIPLKRMGTPHEIAELIVFLASPAASFITGAEYII
EECCCCCCHHEEECCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCHHHHHCCCCEEE
DGGITSM
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]