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The map label for this gene is yccK [H]

Identifier: 159897701

GI number: 159897701

Start: 1345674

End: 1346669

Strand: Reverse

Name: yccK [H]

Synonym: Haur_1172

Alternate gene names: 159897701

Gene position: 1346669-1345674 (Counterclockwise)

Preceding gene: 159897702

Following gene: 159897699

Centisome position: 21.22

GC content: 52.01

Gene sequence:

>996_bases
ATGCAACAACGAACGCTTGGCACGACTGGCTTGGTTGTCTCGGAAATTGGCTTGGGCTGTATGGGCATGAGCCAAAGCTA
TGGCCCTGGCGGCGATAAACAATCAGCAATTAACTTAATCCATACAGCGGTTGAACGCGGCGTAACCTTCTTCGATACCG
CCGAAGTCTATGGCCCCTATATCAACGAGGAATTGGTTGGCGAGGCGCTTGAGCCATTTCGCAACCACGTCGTGATTGCT
ACCAAGTTTGGTTTTAACTTACACCCCGATGGCAAACCAGGCTGGTCGGGAGTCAACAGCCATCCTGATCAGATTAAACG
GGTGGCGGAAGCATCGCTCAAACGCCTACGGATCGAAGCGATCGATTTGTTCTATCAACATCGCGTCGATCCGAATGTGC
CAATTGAAGAAGTTGCGGGTGCAGTCAAGGATCTCATTCAGCAAGGCAAAGTTAAGCATTTTGGGCTTTCTGAGGCAGGC
GCACAAACGATTCGCCGTGCCCACGCGGTTCAGCCTGTCGCCGCCTTGCAAAGCGAATATTCCTTGTGGACCCGCGAACC
AGAAGCTGAAATTATGCCGACGCTGGCAGAATTGGGGATTGGCTTTGTGCCATTCAGCCCACTAGGCAAGGGCTTTTTGA
CTGGTAAAATCGACCAAAGCACCGTCTTTGCCCAAGGCGATATTCGTAATCGAATTCCACGATTTTCGCCTGAAGCCCTG
CAAGCCAACCAAGCCTTGATCGATTTGCTCGAAGCGATTGCCGCGCAAAAACAGGCCACTACTGCGCAAATTGCCTTGGC
ATGGTTACTAGCGCAAAAACCATGGATCGTGCCGATTCCAGGCACGCGCCGCGTAGAACGCTTGGAAGAAAATCTGGGCG
CGGCAGCAATTCGCCTAAACGAGGCTGATTTACAAGCAATCGAGCAAGCCGCCGCTTCAGTGAACATCCAAGGCGCACGC
TACCCCGAAGATTTAGAAAAAATGACTGGTTTGTAG

Upstream 100 bases:

>100_bases
CTTTAGAGCATTGGGCAATAAGCTAAGAGAAATAGGCAAGCGATTGCAGCCTCAAGATCTATACTGTTGTAGCACAAATT
TCAACTGCAAGGAGTTTGCA

Downstream 100 bases:

>100_bases
GAAATATACTGAGGCGTTGGACGTTACCAGCGCCTCTTTTTACTTATCAGGCGGGTTTGGCCCAGGAATTGGCTCAGGCT
CAATTACTGGTTCAAGCCCA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MQQRTLGTTGLVVSEIGLGCMGMSQSYGPGGDKQSAINLIHTAVERGVTFFDTAEVYGPYINEELVGEALEPFRNHVVIA
TKFGFNLHPDGKPGWSGVNSHPDQIKRVAEASLKRLRIEAIDLFYQHRVDPNVPIEEVAGAVKDLIQQGKVKHFGLSEAG
AQTIRRAHAVQPVAALQSEYSLWTREPEAEIMPTLAELGIGFVPFSPLGKGFLTGKIDQSTVFAQGDIRNRIPRFSPEAL
QANQALIDLLEAIAAQKQATTAQIALAWLLAQKPWIVPIPGTRRVERLEENLGAAAIRLNEADLQAIEQAAASVNIQGAR
YPEDLEKMTGL

Sequences:

>Translated_331_residues
MQQRTLGTTGLVVSEIGLGCMGMSQSYGPGGDKQSAINLIHTAVERGVTFFDTAEVYGPYINEELVGEALEPFRNHVVIA
TKFGFNLHPDGKPGWSGVNSHPDQIKRVAEASLKRLRIEAIDLFYQHRVDPNVPIEEVAGAVKDLIQQGKVKHFGLSEAG
AQTIRRAHAVQPVAALQSEYSLWTREPEAEIMPTLAELGIGFVPFSPLGKGFLTGKIDQSTVFAQGDIRNRIPRFSPEAL
QANQALIDLLEAIAAQKQATTAQIALAWLLAQKPWIVPIPGTRRVERLEENLGAAAIRLNEADLQAIEQAAASVNIQGAR
YPEDLEKMTGL
>Mature_331_residues
MQQRTLGTTGLVVSEIGLGCMGMSQSYGPGGDKQSAINLIHTAVERGVTFFDTAEVYGPYINEELVGEALEPFRNHVVIA
TKFGFNLHPDGKPGWSGVNSHPDQIKRVAEASLKRLRIEAIDLFYQHRVDPNVPIEEVAGAVKDLIQQGKVKHFGLSEAG
AQTIRRAHAVQPVAALQSEYSLWTREPEAEIMPTLAELGIGFVPFSPLGKGFLTGKIDQSTVFAQGDIRNRIPRFSPEAL
QANQALIDLLEAIAAQKQATTAQIALAWLLAQKPWIVPIPGTRRVERLEENLGAAAIRLNEADLQAIEQAAASVNIQGAR
YPEDLEKMTGL

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436971, Length=311, Percent_Identity=30.5466237942122, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI27436969, Length=322, Percent_Identity=29.5031055900621, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI4504825, Length=319, Percent_Identity=29.4670846394984, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI27436964, Length=314, Percent_Identity=30.8917197452229, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI27436966, Length=314, Percent_Identity=30.8917197452229, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI27436962, Length=314, Percent_Identity=30.8917197452229, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI223718702, Length=227, Percent_Identity=31.7180616740088, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI41327764, Length=275, Percent_Identity=29.0909090909091, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI41152114, Length=205, Percent_Identity=31.219512195122, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI87081735, Length=320, Percent_Identity=33.75, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1789375, Length=331, Percent_Identity=30.2114803625378, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1787674, Length=315, Percent_Identity=31.1111111111111, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1788070, Length=329, Percent_Identity=31.306990881459, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788081, Length=314, Percent_Identity=24.203821656051, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI48994888, Length=296, Percent_Identity=26.6891891891892, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789199, Length=353, Percent_Identity=25.4957507082153, Blast_Score=72, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=345, Percent_Identity=28.4057971014493, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6325384, Length=347, Percent_Identity=27.9538904899135, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6323998, Length=318, Percent_Identity=27.3584905660377, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319958, Length=291, Percent_Identity=25.4295532646048, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319951, Length=321, Percent_Identity=26.791277258567, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6322615, Length=254, Percent_Identity=24.8031496062992, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24640980, Length=355, Percent_Identity=23.0985915492958, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI45549126, Length=355, Percent_Identity=23.6619718309859, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24646159, Length=230, Percent_Identity=26.9565217391304, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646155, Length=163, Percent_Identity=31.2883435582822, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36031; Mature: 36031

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQRTLGTTGLVVSEIGLGCMGMSQSYGPGGDKQSAINLIHTAVERGVTFFDTAEVYGPY
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHCCC
INEELVGEALEPFRNHVVIATKFGFNLHPDGKPGWSGVNSHPDQIKRVAEASLKRLRIEA
CCHHHHHHHHHHHHCCEEEEEECCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IDLFYQHRVDPNVPIEEVAGAVKDLIQQGKVKHFGLSEAGAQTIRRAHAVQPVAALQSEY
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SLWTREPEAEIMPTLAELGIGFVPFSPLGKGFLTGKIDQSTVFAQGDIRNRIPRFSPEAL
HHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCEEEECCCHHHCCCCCCHHHH
QANQALIDLLEAIAAQKQATTAQIALAWLLAQKPWIVPIPGTRRVERLEENLGAAAIRLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCEEEEEC
EADLQAIEQAAASVNIQGARYPEDLEKMTGL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MQQRTLGTTGLVVSEIGLGCMGMSQSYGPGGDKQSAINLIHTAVERGVTFFDTAEVYGPY
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHCCC
INEELVGEALEPFRNHVVIATKFGFNLHPDGKPGWSGVNSHPDQIKRVAEASLKRLRIEA
CCHHHHHHHHHHHHCCEEEEEECCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IDLFYQHRVDPNVPIEEVAGAVKDLIQQGKVKHFGLSEAGAQTIRRAHAVQPVAALQSEY
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SLWTREPEAEIMPTLAELGIGFVPFSPLGKGFLTGKIDQSTVFAQGDIRNRIPRFSPEAL
HHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCEEEECCCHHHCCCCCCHHHH
QANQALIDLLEAIAAQKQATTAQIALAWLLAQKPWIVPIPGTRRVERLEENLGAAAIRLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCEEEEEC
EADLQAIEQAAASVNIQGARYPEDLEKMTGL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]