| Definition | Herpetosiphon aurantiacus ATCC 23779 chromosome, complete genome. |
|---|---|
| Accession | NC_009972 |
| Length | 6,346,587 |
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The map label for this gene is fadH [H]
Identifier: 159897500
GI number: 159897500
Start: 1113703
End: 1114557
Strand: Direct
Name: fadH [H]
Synonym: Haur_0971
Alternate gene names: 159897500
Gene position: 1113703-1114557 (Clockwise)
Preceding gene: 159897499
Following gene: 159897501
Centisome position: 17.55
GC content: 53.92
Gene sequence:
>855_bases ATGTTTCGTTCAGATCTGCTCAAAGACAAAGTGATCATCATCACTGGTGGGGGTTCGGGCTTGGGGCGTTCAATGGGTGA GCGCTTCCTGGAGTTGGGGGCAAAGTTGGCAATTACCAGCCGCAATGCCGAAAAATTAAGCACTGTGGCCAACGAAATGA TGGCAGCCAAAGGCGGCGAGGTCTTTACCGTGCCCTGCGATGTGCGCGACCCCGAAGCAGTTGACCAGATGATCGAGGCC GTTTGGAACCATTTCGGGACAGTCGATATTTTGGTCAACAATGCTGCTGGCAACTTTATCAGCCCAACCGAGAAGCTTTC ACATCGCGCAGTTGATGCTGTTTTGGGGATTGTGCTGCATGGCACGTTCTACTGCACCTTGGCTTTAGGCAAAAAGTGGA TCGAAGCTGGACGTGGTGGTCAATGTTTGAACATCGTTACAACCTATGCTTGGTCGGGTAGTGGCTTTGTTGTGCCATCG GCGGCAGCCAAAGCTGGGGTTTTGGCCCTGACCCGCTCGTTGGCGGTCGAATGGGCACGCTATGGTATTCGCATGAATGC AATCGCACCTGGCCCCTTCCCCACTCAAGGCGCGTGGGAACGACTTGCCCCAACCCCCGAATTGGCCGAACAAGCACTCA ATCGCGTGCCTTTACGCCGTGTTGGCGAACATATTGAGCTGGCCAATTTGGCCGCCTATATGTTGGCCGACGAAGCAGGC TATATCAACGGCGAATGCATCACGATTGATGGCGGCGAGTGGCTGTATGGCGCTGGCCAATTCTCAGGGCTTGATCGTTT GCCCAACGAAATGTGGGATATGCTCTCCAAAATGACCAAGAAAAGCGGCAGCTAA
Upstream 100 bases:
>100_bases GAAGCTGAAGCCGTGACCGTCTCGTACCCAACATTCTGGCAGCATTACGCGCAGATCAAAGAAGCCTGATCGCGCCGATA GCCCAACAAGGAGGTTGTGC
Downstream 100 bases:
>100_bases GTGATAGATCATCGGGCATAAAAGTCAGGCTATCGACTATATGTAATGGTTTATTGCCGGAACAACGGCCATCATGCCCT CACCCCTCCCTTTCCCGCAC
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 284; Mature: 284
Protein sequence:
>284_residues MFRSDLLKDKVIIITGGGSGLGRSMGERFLELGAKLAITSRNAEKLSTVANEMMAAKGGEVFTVPCDVRDPEAVDQMIEA VWNHFGTVDILVNNAAGNFISPTEKLSHRAVDAVLGIVLHGTFYCTLALGKKWIEAGRGGQCLNIVTTYAWSGSGFVVPS AAAKAGVLALTRSLAVEWARYGIRMNAIAPGPFPTQGAWERLAPTPELAEQALNRVPLRRVGEHIELANLAAYMLADEAG YINGECITIDGGEWLYGAGQFSGLDRLPNEMWDMLSKMTKKSGS
Sequences:
>Translated_284_residues MFRSDLLKDKVIIITGGGSGLGRSMGERFLELGAKLAITSRNAEKLSTVANEMMAAKGGEVFTVPCDVRDPEAVDQMIEA VWNHFGTVDILVNNAAGNFISPTEKLSHRAVDAVLGIVLHGTFYCTLALGKKWIEAGRGGQCLNIVTTYAWSGSGFVVPS AAAKAGVLALTRSLAVEWARYGIRMNAIAPGPFPTQGAWERLAPTPELAEQALNRVPLRRVGEHIELANLAAYMLADEAG YINGECITIDGGEWLYGAGQFSGLDRLPNEMWDMLSKMTKKSGS >Mature_284_residues MFRSDLLKDKVIIITGGGSGLGRSMGERFLELGAKLAITSRNAEKLSTVANEMMAAKGGEVFTVPCDVRDPEAVDQMIEA VWNHFGTVDILVNNAAGNFISPTEKLSHRAVDAVLGIVLHGTFYCTLALGKKWIEAGRGGQCLNIVTTYAWSGSGFVVPS AAAKAGVLALTRSLAVEWARYGIRMNAIAPGPFPTQGAWERLAPTPELAEQALNRVPLRRVGEHIELANLAAYMLADEAG YINGECITIDGGEWLYGAGQFSGLDRLPNEMWDMLSKMTKKSGS
Specific function: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily [H]
Homologues:
Organism=Homo sapiens, GI4503301, Length=251, Percent_Identity=45.4183266932271, Blast_Score=233, Evalue=1e-61, Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=36.328125, Blast_Score=173, Evalue=2e-43, Organism=Homo sapiens, GI10190704, Length=265, Percent_Identity=37.7358490566038, Blast_Score=168, Evalue=6e-42, Organism=Homo sapiens, GI40254992, Length=253, Percent_Identity=31.2252964426877, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=27.9527559055118, Blast_Score=98, Evalue=9e-21, Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=26.5873015873016, Blast_Score=88, Evalue=9e-18, Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=27.6923076923077, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI5031737, Length=252, Percent_Identity=26.984126984127, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI59889578, Length=236, Percent_Identity=30.9322033898305, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI31542939, Length=193, Percent_Identity=31.6062176165803, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI4758504, Length=259, Percent_Identity=32.046332046332, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI157739938, Length=246, Percent_Identity=26.8292682926829, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI66933014, Length=251, Percent_Identity=28.6852589641434, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI20149619, Length=201, Percent_Identity=28.3582089552239, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI209862901, Length=218, Percent_Identity=25.2293577981651, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI19923983, Length=218, Percent_Identity=25.2293577981651, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI126723750, Length=261, Percent_Identity=24.1379310344828, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI224922801, Length=175, Percent_Identity=30.2857142857143, Blast_Score=65, Evalue=9e-11, Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=30.8, Blast_Score=117, Evalue=9e-28, Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=33.2046332046332, Blast_Score=106, Evalue=2e-24, Organism=Escherichia coli, GI1787905, Length=258, Percent_Identity=30.2325581395349, Blast_Score=105, Evalue=3e-24, Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=28.0487804878049, Blast_Score=104, Evalue=6e-24, Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=29.6747967479675, Blast_Score=104, Evalue=6e-24, Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=28.4552845528455, Blast_Score=101, Evalue=5e-23, Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=29.0322580645161, Blast_Score=94, Evalue=9e-21, Organism=Escherichia coli, GI1788459, Length=255, Percent_Identity=25.0980392156863, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=25.5813953488372, Blast_Score=87, Evalue=2e-18, Organism=Escherichia coli, GI1789378, Length=260, Percent_Identity=26.1538461538462, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=27.3092369477912, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=27.3224043715847, Blast_Score=65, Evalue=5e-12, Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=24.609375, Blast_Score=61, Evalue=7e-11, Organism=Caenorhabditis elegans, GI17536025, Length=266, Percent_Identity=42.8571428571429, Blast_Score=212, Evalue=2e-55, Organism=Caenorhabditis elegans, GI17536651, Length=266, Percent_Identity=40.9774436090226, Blast_Score=204, Evalue=3e-53, Organism=Caenorhabditis elegans, GI17561272, Length=256, Percent_Identity=43.359375, Blast_Score=196, Evalue=1e-50, Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=32.1969696969697, Blast_Score=113, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=28.6852589641434, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=28.4644194756554, Blast_Score=99, Evalue=4e-21, Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=29.6, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=27.4809160305344, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17563726, Length=268, Percent_Identity=29.4776119402985, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=30.5660377358491, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=28.6259541984733, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562990, Length=276, Percent_Identity=28.6231884057971, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=28.1954887218045, Blast_Score=88, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=27.1653543307087, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17560332, Length=275, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=27.4436090225564, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=28.6290322580645, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=27.8625954198473, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=27.2388059701493, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=23.6734693877551, Blast_Score=79, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17565030, Length=263, Percent_Identity=26.615969581749, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17538182, Length=257, Percent_Identity=28.4046692607004, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=26.9662921348315, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=27.0992366412214, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=26.7175572519084, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=27.4809160305344, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=24.2063492063492, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=23.5059760956175, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17567345, Length=177, Percent_Identity=29.3785310734463, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI71997099, Length=233, Percent_Identity=25.7510729613734, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI71982365, Length=198, Percent_Identity=25.7575757575758, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=280, Percent_Identity=32.8571428571429, Blast_Score=136, Evalue=4e-33, Organism=Saccharomyces cerevisiae, GI6322861, Length=193, Percent_Identity=27.979274611399, Blast_Score=70, Evalue=4e-13, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=30.1587301587302, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=29.2, Blast_Score=100, Evalue=2e-21, Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=28, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=28.1746031746032, Blast_Score=95, Evalue=6e-20, Organism=Drosophila melanogaster, GI17737361, Length=259, Percent_Identity=31.2741312741313, Blast_Score=92, Evalue=5e-19, Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=28.7937743190661, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=27.8225806451613, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=26.0162601626016, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI21358495, Length=206, Percent_Identity=28.1553398058252, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24644337, Length=254, Percent_Identity=27.5590551181102, Blast_Score=68, Evalue=9e-12, Organism=Drosophila melanogaster, GI24665243, Length=188, Percent_Identity=28.7234042553192, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI21357673, Length=246, Percent_Identity=24.390243902439, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24580925, Length=199, Percent_Identity=26.6331658291457, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI221331218, Length=188, Percent_Identity=28.7234042553192, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.3.1.34 [H]
Molecular weight: Translated: 30504; Mature: 30504
Theoretical pI: Translated: 6.14; Mature: 6.14
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 3.5 %Met (Translated Protein) 4.9 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 3.5 %Met (Mature Protein) 4.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFRSDLLKDKVIIITGGGSGLGRSMGERFLELGAKLAITSRNAEKLSTVANEMMAAKGGE CCCCHHCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCC VFTVPCDVRDPEAVDQMIEAVWNHFGTVDILVNNAAGNFISPTEKLSHRAVDAVLGIVLH EEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH GTFYCTLALGKKWIEAGRGGQCLNIVTTYAWSGSGFVVPSAAAKAGVLALTRSLAVEWAR HHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHH YGIRMNAIAPGPFPTQGAWERLAPTPELAEQALNRVPLRRVGEHIELANLAAYMLADEAG HCEEEEEECCCCCCCCCCHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC YINGECITIDGGEWLYGAGQFSGLDRLPNEMWDMLSKMTKKSGS CCCCEEEEEECCCEEEECCCCCCHHCCHHHHHHHHHHHHHCCCC >Mature Secondary Structure MFRSDLLKDKVIIITGGGSGLGRSMGERFLELGAKLAITSRNAEKLSTVANEMMAAKGGE CCCCHHCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCC VFTVPCDVRDPEAVDQMIEAVWNHFGTVDILVNNAAGNFISPTEKLSHRAVDAVLGIVLH EEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH GTFYCTLALGKKWIEAGRGGQCLNIVTTYAWSGSGFVVPSAAAKAGVLALTRSLAVEWAR HHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHH YGIRMNAIAPGPFPTQGAWERLAPTPELAEQALNRVPLRRVGEHIELANLAAYMLADEAG HCEEEEEECCCCCCCCCCHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC YINGECITIDGGEWLYGAGQFSGLDRLPNEMWDMLSKMTKKSGS CCCCEEEEEECCCEEEECCCCCCHHCCHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]