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The map label for this gene is prpC [H]

Identifier: 159897427

GI number: 159897427

Start: 1028693

End: 1030024

Strand: Direct

Name: prpC [H]

Synonym: Haur_0898

Alternate gene names: 159897427

Gene position: 1028693-1030024 (Clockwise)

Preceding gene: 159897422

Following gene: 159897428

Centisome position: 16.21

GC content: 54.13

Gene sequence:

>1332_bases
ATGAGCCTTGCAACGCCTACTGGCGCTCCATGCCCTCGCTGTCAGCGCCTTGTTGATGAAACGGCCCGTTTTTGCCGTTA
TTGTGGCTTTCCGCTGCGTTCAGTCGCAACGCAGCCAGTATCAACAACGCCCGAGCCAGCTACGGCAGCCGAGCCGATCG
ACTATGAAGAAGTTGTTTTACCCGCACCGCGTCGCATTCAGCTTGAAGGCGAGAAGATCAGCCTGCGAGCCTTGGAACAG
ATGGTGCATGCTGGCGTTGAATGGTGGCAGATGCGCTTGCAAACTGGTGAAGCAACCCGTGAAGAGGCAATCAGTAGTAT
TGAAGAGTTGCGGAAAGCCCTTGGAAGCGTTAGTCATCAGTTGGCTCAAGGCCGTGAAACTATTCGCATTACCACCACGT
TAACGCCCGCCCGCCGCTTTCCGCTGGGCTGCTCGCGCTGCGGCAAGGGCAATCGGGTGAATGCACGTTATTGCATTGCC
TGTGGTAATCCATTGGTGGCTAATGCAGAAAAGGTCCAGCCTATGTCCCAAACACTTCGCTATACTGTTGGTCTGCTTTC
CGATGTTGGTACTCGCCGTTCAGTCAACCAAGATTCTGCCTTGGTCGAGCAGTTTCGCTTGCGTGATGGCACGCCTGTGA
TCTGTTGTTTGGTGGCTGATGGCATGGGTGGTGCTCAAGGCGGCGAACGAGCCAGCGCCTTGGCTAGTCAAACAATTGTG
AATCATCTGCGCGATTATAGCCGCAATGTTGATCGCAGCTTTGATGGCTGGCGCGATGTTGTGCGAGCTGCAATCGCTGC
GGCCAATAGCACGATCTTTCGCGAAGCTGAAGTTAAATCAACCTTACGTGGTATGGGCACGACGGTGGTCGTGGCCTTGG
TGATTGGTGAAAAAGCTTGGATTGGCAGCGTTGGTGATTCGCGAGTCTACCTATTTAATCGTAAAGGGGTCAGTGAACAC
ACTCAACAAATCGCCCAAATCACAGTAGATCACACCATGGTGGCCCGCTTAGTTGACATTGGCGAGCTAACGTCTGAACA
AGCCCGTACTCACCCGCGTCGCCATGTGCTTTATCGCTCGGTCGGCGTAGAAGCCACGGTCGAATCGGACATGACTGAGC
AGCCGCTTGAGGCTGGCGATTGGCTGTTGCTCTGCTCCGATGGCTTGATCAACGAGCTTTCGGATGAAGAATTGCGTGAT
GCAGTCTTTGAAGCCTCATCGCCACAAGCATGCTGTGGCAGCCTGATTGCTATTGCCAATAGTCGTGGAGCACGCGATAA
TGTGACCGTGGTGTTATTGTCGGCAGAAGAACGCACCGACCAGCAGCACTAG

Upstream 100 bases:

>100_bases
GGCTGTGCTATAATCGCAGCATGTGAGCAGACTCAAACACGCGCATTATAGCATACTGCTCCAGACCACAACCGTTCCTG
CCGAATGGGAGGTTGCTCGA

Downstream 100 bases:

>100_bases
TGGCCTGTGGCTGAAACTAATTAAAGATTGTCTGCGTCTTATGCTGTGACGGCCTTACGCCAGCGATCACATCCTGATCG
TTTTGTCACGATTCTGGGCG

Product: protein serine/threonine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MSLATPTGAPCPRCQRLVDETARFCRYCGFPLRSVATQPVSTTPEPATAAEPIDYEEVVLPAPRRIQLEGEKISLRALEQ
MVHAGVEWWQMRLQTGEATREEAISSIEELRKALGSVSHQLAQGRETIRITTTLTPARRFPLGCSRCGKGNRVNARYCIA
CGNPLVANAEKVQPMSQTLRYTVGLLSDVGTRRSVNQDSALVEQFRLRDGTPVICCLVADGMGGAQGGERASALASQTIV
NHLRDYSRNVDRSFDGWRDVVRAAIAAANSTIFREAEVKSTLRGMGTTVVVALVIGEKAWIGSVGDSRVYLFNRKGVSEH
TQQIAQITVDHTMVARLVDIGELTSEQARTHPRRHVLYRSVGVEATVESDMTEQPLEAGDWLLLCSDGLINELSDEELRD
AVFEASSPQACCGSLIAIANSRGARDNVTVVLLSAEERTDQQH

Sequences:

>Translated_443_residues
MSLATPTGAPCPRCQRLVDETARFCRYCGFPLRSVATQPVSTTPEPATAAEPIDYEEVVLPAPRRIQLEGEKISLRALEQ
MVHAGVEWWQMRLQTGEATREEAISSIEELRKALGSVSHQLAQGRETIRITTTLTPARRFPLGCSRCGKGNRVNARYCIA
CGNPLVANAEKVQPMSQTLRYTVGLLSDVGTRRSVNQDSALVEQFRLRDGTPVICCLVADGMGGAQGGERASALASQTIV
NHLRDYSRNVDRSFDGWRDVVRAAIAAANSTIFREAEVKSTLRGMGTTVVVALVIGEKAWIGSVGDSRVYLFNRKGVSEH
TQQIAQITVDHTMVARLVDIGELTSEQARTHPRRHVLYRSVGVEATVESDMTEQPLEAGDWLLLCSDGLINELSDEELRD
AVFEASSPQACCGSLIAIANSRGARDNVTVVLLSAEERTDQQH
>Mature_442_residues
SLATPTGAPCPRCQRLVDETARFCRYCGFPLRSVATQPVSTTPEPATAAEPIDYEEVVLPAPRRIQLEGEKISLRALEQM
VHAGVEWWQMRLQTGEATREEAISSIEELRKALGSVSHQLAQGRETIRITTTLTPARRFPLGCSRCGKGNRVNARYCIAC
GNPLVANAEKVQPMSQTLRYTVGLLSDVGTRRSVNQDSALVEQFRLRDGTPVICCLVADGMGGAQGGERASALASQTIVN
HLRDYSRNVDRSFDGWRDVVRAAIAAANSTIFREAEVKSTLRGMGTTVVVALVIGEKAWIGSVGDSRVYLFNRKGVSEHT
QQIAQITVDHTMVARLVDIGELTSEQARTHPRRHVLYRSVGVEATVESDMTEQPLEAGDWLLLCSDGLINELSDEELRDA
VFEASSPQACCGSLIAIANSRGARDNVTVVLLSAEERTDQQH

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 48416; Mature: 48285

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLATPTGAPCPRCQRLVDETARFCRYCGFPLRSVATQPVSTTPEPATAAEPIDYEEVVL
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHEEC
PAPRRIQLEGEKISLRALEQMVHAGVEWWQMRLQTGEATREEAISSIEELRKALGSVSHQ
CCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LAQGRETIRITTTLTPARRFPLGCSRCGKGNRVNARYCIACGNPLVANAEKVQPMSQTLR
HHCCCCEEEEEEEECCHHHCCCCHHHCCCCCCCCCEEEEEECCCCCCCHHHHCHHHHHHH
YTVGLLSDVGTRRSVNQDSALVEQFRLRDGTPVICCLVADGMGGAQGGERASALASQTIV
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHH
NHLRDYSRNVDRSFDGWRDVVRAAIAAANSTIFREAEVKSTLRGMGTTVVVALVIGEKAW
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHH
IGSVGDSRVYLFNRKGVSEHTQQIAQITVDHTMVARLVDIGELTSEQARTHPRRHVLYRS
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VGVEATVESDMTEQPLEAGDWLLLCSDGLINELSDEELRDAVFEASSPQACCGSLIAIAN
CCCCEEECCCCCCCCCCCCCEEEEECCCHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHC
SRGARDNVTVVLLSAEERTDQQH
CCCCCCCEEEEEEECHHCCCCCC
>Mature Secondary Structure 
SLATPTGAPCPRCQRLVDETARFCRYCGFPLRSVATQPVSTTPEPATAAEPIDYEEVVL
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHEEC
PAPRRIQLEGEKISLRALEQMVHAGVEWWQMRLQTGEATREEAISSIEELRKALGSVSHQ
CCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LAQGRETIRITTTLTPARRFPLGCSRCGKGNRVNARYCIACGNPLVANAEKVQPMSQTLR
HHCCCCEEEEEEEECCHHHCCCCHHHCCCCCCCCCEEEEEECCCCCCCHHHHCHHHHHHH
YTVGLLSDVGTRRSVNQDSALVEQFRLRDGTPVICCLVADGMGGAQGGERASALASQTIV
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHH
NHLRDYSRNVDRSFDGWRDVVRAAIAAANSTIFREAEVKSTLRGMGTTVVVALVIGEKAW
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHH
IGSVGDSRVYLFNRKGVSEHTQQIAQITVDHTMVARLVDIGELTSEQARTHPRRHVLYRS
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VGVEATVESDMTEQPLEAGDWLLLCSDGLINELSDEELRDAVFEASSPQACCGSLIAIAN
CCCCEEECCCCCCCCCCCCCEEEEECCCHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHC
SRGARDNVTVVLLSAEERTDQQH
CCCCCCCEEEEEEECHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]