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The map label for this gene is manA [H]

Identifier: 159897414

GI number: 159897414

Start: 1010793

End: 1011773

Strand: Reverse

Name: manA [H]

Synonym: Haur_0885

Alternate gene names: 159897414

Gene position: 1011773-1010793 (Counterclockwise)

Preceding gene: 159897415

Following gene: 159897413

Centisome position: 15.94

GC content: 54.13

Gene sequence:

>981_bases
ATGAGCGTGATCGAGCTCTATCCGTTGCTGACCCAAGCACGCTATGTCGAGCCAATTTGGGGTGGTCCCCAATTGGCTCG
CTGGCTGCACTTGCCTGAAGCCGAGCAAAGCAAGCTAGGCGAAATTTGGCAAGTCTACGATCAAAATCTGATCGTCAATG
GCGCGTTGGCTGGCCAAAGTTTAGCCCAAGTTACCAGCCAATTTGGGGCCGCCTTGGTTGGCACAACCACCAGCGAACGC
TATGGCAACGATTTTCCGTTGTTGTTGAAATTCATCGCCGCCGCCCAACCGCTCTCGGTGCAGGTGCATCCCGACGATGA
GTACGCCCACAGCCGCGAGGCCGCGTCGGGTTTTCACGGCAAAACCGAGGCTTGGTACATTCTCGAAGCTGAAAACGGAG
CCGAGGTTGTGCATGGCTTCCGCGAGGCAACCAATCGCCAAGCCTGCGAAGCGGCCTTAGCCACCAATACACTGCCTGAA
TTATTACGTCAAGTCGCGGTGCAAGCAGGCGATTTGGTATTTGTGCCAGCCAAAACGATTCATGCGATCAATCCTGGGGT
GGTGCTGTTCGAAATTCAGCAAAAATCCGATCTGACCTATCGGGTCTACGATTACGATCGGCGTGATGCTGCCACAGGCT
TGCCGCGCCAACTGCATCTTGAGCAAGCGTTCGAGGTGTTGGATTTTGCGGCAACTGCGCCGGCTTTAGTAACACCGACC
AAGTTGAATGCTGATGTCAGTTTGCTGGTACGCTGTCCATTTTTCAGCTTAGAGCACTGGCAACTCAATCGCATCCAAGC
ACTGAGCACCTCGGTAACCAGTTTCGATTGTTGGACGGTGATCAATGGCGCTTGTAGTTTGGTTTGGGGCGCAGGCAGCC
TTGATCTTAGCCATGGCATGTCGGTGATCGTGCCTGCGCAATTAGGCCAATATCAACTCTACCCTGAACCAAGCGCCGAA
TTGCTTCGGGCGTATGTGTAG

Upstream 100 bases:

>100_bases
CGGTTTGGCAATTCAACCGCCATGAAGGCGGCGAAAACTTCCAAACCTTGGAAAAACTGAAATTCCTCACCAAACTGTGG
GGCAACGAGGAACGCACTGC

Downstream 100 bases:

>100_bases
GACTGGGGGTCGGCGGTTGGTGGTCGGGGATCAGATAAAAGGCTAGCAACTAAATGAAATGGGTCATTGGGTTAACGTGC
CCTCACCCCCAGCCCCTCTC

Product: mannose-6-phosphate isomerase

Products: NA

Alternate protein names: Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSVIELYPLLTQARYVEPIWGGPQLARWLHLPEAEQSKLGEIWQVYDQNLIVNGALAGQSLAQVTSQFGAALVGTTTSER
YGNDFPLLLKFIAAAQPLSVQVHPDDEYAHSREAASGFHGKTEAWYILEAENGAEVVHGFREATNRQACEAALATNTLPE
LLRQVAVQAGDLVFVPAKTIHAINPGVVLFEIQQKSDLTYRVYDYDRRDAATGLPRQLHLEQAFEVLDFAATAPALVTPT
KLNADVSLLVRCPFFSLEHWQLNRIQALSTSVTSFDCWTVINGACSLVWGAGSLDLSHGMSVIVPAQLGQYQLYPEPSAE
LLRAYV

Sequences:

>Translated_326_residues
MSVIELYPLLTQARYVEPIWGGPQLARWLHLPEAEQSKLGEIWQVYDQNLIVNGALAGQSLAQVTSQFGAALVGTTTSER
YGNDFPLLLKFIAAAQPLSVQVHPDDEYAHSREAASGFHGKTEAWYILEAENGAEVVHGFREATNRQACEAALATNTLPE
LLRQVAVQAGDLVFVPAKTIHAINPGVVLFEIQQKSDLTYRVYDYDRRDAATGLPRQLHLEQAFEVLDFAATAPALVTPT
KLNADVSLLVRCPFFSLEHWQLNRIQALSTSVTSFDCWTVINGACSLVWGAGSLDLSHGMSVIVPAQLGQYQLYPEPSAE
LLRAYV
>Mature_325_residues
SVIELYPLLTQARYVEPIWGGPQLARWLHLPEAEQSKLGEIWQVYDQNLIVNGALAGQSLAQVTSQFGAALVGTTTSERY
GNDFPLLLKFIAAAQPLSVQVHPDDEYAHSREAASGFHGKTEAWYILEAENGAEVVHGFREATNRQACEAALATNTLPEL
LRQVAVQAGDLVFVPAKTIHAINPGVVLFEIQQKSDLTYRVYDYDRRDAATGLPRQLHLEQAFEVLDFAATAPALVTPTK
LNADVSLLVRCPFFSLEHWQLNRIQALSTSVTSFDCWTVINGACSLVWGAGSLDLSHGMSVIVPAQLGQYQLYPEPSAEL
LRAYV

Specific function: Involved In The Conversion Of Glucose To Gdp-L-Fucose, Which Can Be Converted To L-Fucose, A Capsular Polysaccharide. [C]

COG id: COG1482

COG function: function code G; Phosphomannose isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR001250
- InterPro:   IPR014628
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01238 PMI_typeI [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 35862; Mature: 35731

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVIELYPLLTQARYVEPIWGGPQLARWLHLPEAEQSKLGEIWQVYDQNLIVNGALAGQS
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCHHH
LAQVTSQFGAALVGTTTSERYGNDFPLLLKFIAAAQPLSVQVHPDDEYAHSREAASGFHG
HHHHHHHHCCEEEECCCHHHCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCC
KTEAWYILEAENGAEVVHGFREATNRQACEAALATNTLPELLRQVAVQAGDLVFVPAKTI
CCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHE
HAINPGVVLFEIQQKSDLTYRVYDYDRRDAATGLPRQLHLEQAFEVLDFAATAPALVTPT
EECCCCEEEEEEECCCCCEEEEEECCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCEECCC
KLNADVSLLVRCPFFSLEHWQLNRIQALSTSVTSFDCWTVINGACSLVWGAGSLDLSHGM
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCEEEEECCCCCCHHCCC
SVIVPAQLGQYQLYPEPSAELLRAYV
EEEEECCCCCEEECCCCHHHHHHHCC
>Mature Secondary Structure 
SVIELYPLLTQARYVEPIWGGPQLARWLHLPEAEQSKLGEIWQVYDQNLIVNGALAGQS
CHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCHHH
LAQVTSQFGAALVGTTTSERYGNDFPLLLKFIAAAQPLSVQVHPDDEYAHSREAASGFHG
HHHHHHHHCCEEEECCCHHHCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCC
KTEAWYILEAENGAEVVHGFREATNRQACEAALATNTLPELLRQVAVQAGDLVFVPAKTI
CCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHE
HAINPGVVLFEIQQKSDLTYRVYDYDRRDAATGLPRQLHLEQAFEVLDFAATAPALVTPT
EECCCCEEEEEEECCCCCEEEEEECCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCEECCC
KLNADVSLLVRCPFFSLEHWQLNRIQALSTSVTSFDCWTVINGACSLVWGAGSLDLSHGM
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCEEEEECCCCCCHHCCC
SVIVPAQLGQYQLYPEPSAELLRAYV
EEEEECCCCCEEECCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]