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The map label for this gene is nudL [H]

Identifier: 159897305

GI number: 159897305

Start: 877487

End: 878146

Strand: Reverse

Name: nudL [H]

Synonym: Haur_0776

Alternate gene names: 159897305

Gene position: 878146-877487 (Counterclockwise)

Preceding gene: 159897306

Following gene: 159897304

Centisome position: 13.84

GC content: 52.58

Gene sequence:

>660_bases
ATGAGATGTATGCCAAATCTAGCGTTCGTGGCGGCTCTCCAAGCGCAACTTGTCAACTTGCAACACGATAATGAGGCTCG
TTCACGGCTTTTACCAATCCTCGGCAACGGCAATCCCAGTCGCGATTTATTACCCCCAGCCCATATTACGCCACGCCATA
GCGCAGTGTTGGCTTTGCTCTATCCGCAAGCTGAGCAGTTGTTTGTGCTATTAACCGTGCGCAGCGGCAATTTGCGCAGC
CATACTGGCGAAATTTCGCTGCCTGGCGGCTCGATCGACCCAACTGATGCCAGCCCTGAGGCCGCCGCGCTGCGCGAAGC
CCACGAAGAGGTTGGCTTGCAAACCCATCAACCCACAATCATCGGGCGCTTGAGCGAATTGTATGTTCCGGTCAGCAATT
TTTTAATCACGCCAATTGTCGCTTGGCTTGATCATGCGCCTGATTTAGCGCCAAACCCGAATGAAGTTGCCGATGTGGTA
CATTTACCTTTGCAGCAGCTTTGGGCCGCCGATGCCGTACAAACTGAAGAACGGATTATTCGTGGCATGACTCTGCAAGT
GCCGCATTATCCTTATGGTGAGCATAAAATTTGGGGCGCAACCTCAATTATTCTGACCCAGCTAGCCTTACGGGTTCAAG
CGGCGCTCCAGCAAATCTAA

Upstream 100 bases:

>100_bases
CTTCGACATCGCCACCGAAAAAGCTTTGATCTAACTCGATCAACTCACGGTATAATAACAAAGACGTAGGAGCAACCTAC
GTCTTTGTTCGTTTAGTGGA

Downstream 100 bases:

>100_bases
AGTATAATGGCGGCTGATTGCTTAACCCTGAGAGCCAATGAAACGGATTCTTGTTTGTACAGCCCAAGTGCCTTTTGCCC
GTGGTGGAGCCGAGTTGTTA

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MRCMPNLAFVAALQAQLVNLQHDNEARSRLLPILGNGNPSRDLLPPAHITPRHSAVLALLYPQAEQLFVLLTVRSGNLRS
HTGEISLPGGSIDPTDASPEAAALREAHEEVGLQTHQPTIIGRLSELYVPVSNFLITPIVAWLDHAPDLAPNPNEVADVV
HLPLQQLWAADAVQTEERIIRGMTLQVPHYPYGEHKIWGATSIILTQLALRVQAALQQI

Sequences:

>Translated_219_residues
MRCMPNLAFVAALQAQLVNLQHDNEARSRLLPILGNGNPSRDLLPPAHITPRHSAVLALLYPQAEQLFVLLTVRSGNLRS
HTGEISLPGGSIDPTDASPEAAALREAHEEVGLQTHQPTIIGRLSELYVPVSNFLITPIVAWLDHAPDLAPNPNEVADVV
HLPLQQLWAADAVQTEERIIRGMTLQVPHYPYGEHKIWGATSIILTQLALRVQAALQQI
>Mature_219_residues
MRCMPNLAFVAALQAQLVNLQHDNEARSRLLPILGNGNPSRDLLPPAHITPRHSAVLALLYPQAEQLFVLLTVRSGNLRS
HTGEISLPGGSIDPTDASPEAAALREAHEEVGLQTHQPTIIGRLSELYVPVSNFLITPIVAWLDHAPDLAPNPNEVADVV
HLPLQQLWAADAVQTEERIIRGMTLQVPHYPYGEHKIWGATSIILTQLALRVQAALQQI

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=146, Percent_Identity=39.7260273972603, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17536993, Length=155, Percent_Identity=31.6129032258064, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI18859683, Length=172, Percent_Identity=33.7209302325581, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 23973; Mature: 23973

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCMPNLAFVAALQAQLVNLQHDNEARSRLLPILGNGNPSRDLLPPAHITPRHSAVLALL
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHEEEEECCCCCCCCCCCCCCCCCCHHEEEEEE
YPQAEQLFVLLTVRSGNLRSHTGEISLPGGSIDPTDASPEAAALREAHEEVGLQTHQPTI
CCCCCEEEEEEEEECCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHH
IGRLSELYVPVSNFLITPIVAWLDHAPDLAPNPNEVADVVHLPLQQLWAADAVQTEERII
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGMTLQVPHYPYGEHKIWGATSIILTQLALRVQAALQQI
CCCEEECCCCCCCCCEECHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRCMPNLAFVAALQAQLVNLQHDNEARSRLLPILGNGNPSRDLLPPAHITPRHSAVLALL
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHEEEEECCCCCCCCCCCCCCCCCCHHEEEEEE
YPQAEQLFVLLTVRSGNLRSHTGEISLPGGSIDPTDASPEAAALREAHEEVGLQTHQPTI
CCCCCEEEEEEEEECCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHH
IGRLSELYVPVSNFLITPIVAWLDHAPDLAPNPNEVADVVHLPLQQLWAADAVQTEERII
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGMTLQVPHYPYGEHKIWGATSIILTQLALRVQAALQQI
CCCEEECCCCCCCCCEECHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]