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The map label for this gene is fabH [H]

Identifier: 159897273

GI number: 159897273

Start: 848934

End: 849920

Strand: Direct

Name: fabH [H]

Synonym: Haur_0744

Alternate gene names: 159897273

Gene position: 848934-849920 (Clockwise)

Preceding gene: 159897272

Following gene: 159897274

Centisome position: 13.38

GC content: 52.28

Gene sequence:

>987_bases
ATGAATGCAGCTATTACTGGTTGGGGGCGCTACGCTCCCGATCGTGTGCTTACAAACCAAGAACTTGAACAAATTGTCGA
TACCAATGATGAATGGATTCAATCGCGGACTGGCATTCAGCGCCGCCATATTGTTGCTGAAGGTCAAGCCACCTCGGATA
TGTCGGCTCGTGCCGCGCGGATTGCCCTCGATAAGGCGGGAGTAAAACCCGAAGAGCTTGATTTAATTGTCGTAGCGACT
ACTTCGCCCGATTTGCTGTTGCCCTCAACTGCCGCCTTAGTTCAAACCAAACTCGGCGCGATCAACGCTGGCGTGATGGA
TATGAATGCTGCTTGCTGTGGCTTTTTATATGCGCTAAGCGCCGTTACAGCCATGATTCGTGGCGGTGGTGTGGGTAAAG
TACTACTCTGCGGAGCAGAAACCATCTCGCCATTTTTAAATTGGCAAGATCGCAACACCTGCGTGATTTTTGGCGATGCT
GCTGGTGCTGTCATTCTTGAAGCGACCGAGCAAGAGCGTGGTTTGCAATCCTACAAACTTGGGGCGATCCCCGATACCGC
CGAATTATTGTGGATCAAAGCTGGCGCGACGCTCTACCCTGCAACTCACGAGCGACTTGATCAGTCTGAACAGTATATTC
AGATGAATGGCTCGGAAGTGTTTAAGCATGCGGTGCGCTCGATGGTCGATAGTTCGTTACATGTGTTGAACCAAGTTGGT
AAAACGCCCGCCGATGTGCAACTGGTTGTTCCGCATCAAGCCAATTTACGCATTATCGAAGCCGTCGCCAAACGCCTGAA
TGTGTCGATGGATCAGGTTTTTGTCAATATTCAAGAATATGGCAATACCTCAGCCGCCACTTTGCCCGTAGCGATCGCTG
AAGCCGCCGATGCTGGCCGCATGCAGCCTGGCGATACGATCTTGCTGACCGCGTTTGGTGGCGGCCTGACCTGGGCTTCG
GGTGTGTTGGTGTGGGGCGGGAAGTAG

Upstream 100 bases:

>100_bases
AGCGAAAGGGTCGAGACCTATGGTTCTCGTCCCTTTCGCATTTTAGGCGCGTTATTGTGCAGTGCAGCATGAAACGGCTT
CACCACGGGAGTGTTTTGCA

Downstream 100 bases:

>100_bases
AACATAGATGTAATGGTTTATAGTTTAACAACGGCCAGCATGCCCTCACCCCCTCTCCCGCACGCGAGGCGAGGGGGAAC
CGCTCTCGGAGTGCTCCCCT

Product: 3-oxoacyl-(acyl-carrier-protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MNAAITGWGRYAPDRVLTNQELEQIVDTNDEWIQSRTGIQRRHIVAEGQATSDMSARAARIALDKAGVKPEELDLIVVAT
TSPDLLLPSTAALVQTKLGAINAGVMDMNAACCGFLYALSAVTAMIRGGGVGKVLLCGAETISPFLNWQDRNTCVIFGDA
AGAVILEATEQERGLQSYKLGAIPDTAELLWIKAGATLYPATHERLDQSEQYIQMNGSEVFKHAVRSMVDSSLHVLNQVG
KTPADVQLVVPHQANLRIIEAVAKRLNVSMDQVFVNIQEYGNTSAATLPVAIAEAADAGRMQPGDTILLTAFGGGLTWAS
GVLVWGGK

Sequences:

>Translated_328_residues
MNAAITGWGRYAPDRVLTNQELEQIVDTNDEWIQSRTGIQRRHIVAEGQATSDMSARAARIALDKAGVKPEELDLIVVAT
TSPDLLLPSTAALVQTKLGAINAGVMDMNAACCGFLYALSAVTAMIRGGGVGKVLLCGAETISPFLNWQDRNTCVIFGDA
AGAVILEATEQERGLQSYKLGAIPDTAELLWIKAGATLYPATHERLDQSEQYIQMNGSEVFKHAVRSMVDSSLHVLNQVG
KTPADVQLVVPHQANLRIIEAVAKRLNVSMDQVFVNIQEYGNTSAATLPVAIAEAADAGRMQPGDTILLTAFGGGLTWAS
GVLVWGGK
>Mature_328_residues
MNAAITGWGRYAPDRVLTNQELEQIVDTNDEWIQSRTGIQRRHIVAEGQATSDMSARAARIALDKAGVKPEELDLIVVAT
TSPDLLLPSTAALVQTKLGAINAGVMDMNAACCGFLYALSAVTAMIRGGGVGKVLLCGAETISPFLNWQDRNTCVIFGDA
AGAVILEATEQERGLQSYKLGAIPDTAELLWIKAGATLYPATHERLDQSEQYIQMNGSEVFKHAVRSMVDSSLHVLNQVG
KTPADVQLVVPHQANLRIIEAVAKRLNVSMDQVFVNIQEYGNTSAATLPVAIAEAADAGRMQPGDTILLTAFGGGLTWAS
GVLVWGGK

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=326, Percent_Identity=42.638036809816, Blast_Score=240, Evalue=7e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34970; Mature: 34970

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAAITGWGRYAPDRVLTNQELEQIVDTNDEWIQSRTGIQRRHIVAEGQATSDMSARAAR
CCCCCCCCCCCCCCHHCCHHHHHHHHCCCHHHHHHHCCCCHHEEEECCCCCCCHHHHHHH
IALDKAGVKPEELDLIVVATTSPDLLLPSTAALVQTKLGAINAGVMDMNAACCGFLYALS
HHHHHCCCCCCCEEEEEEEECCCCEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
AVTAMIRGGGVGKVLLCGAETISPFLNWQDRNTCVIFGDAAGAVILEATEQERGLQSYKL
HHHHHHHCCCCCEEEEECCHHHHHHCCCCCCCEEEEEECCCCEEEEEECHHHCCHHHEEC
GAIPDTAELLWIKAGATLYPATHERLDQSEQYIQMNGSEVFKHAVRSMVDSSLHVLNQVG
CCCCCCCEEEEEECCCEECCCHHHHHCCCHHHEECCHHHHHHHHHHHHHHHHHHHHHHHC
KTPADVQLVVPHQANLRIIEAVAKRLNVSMDQVFVNIQEYGNTSAATLPVAIAEAADAGR
CCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHEEEHHHCCCCCCCEEEEEEEHHCCCCC
MQPGDTILLTAFGGGLTWASGVLVWGGK
CCCCCEEEEEECCCCCHHHCCEEEECCC
>Mature Secondary Structure
MNAAITGWGRYAPDRVLTNQELEQIVDTNDEWIQSRTGIQRRHIVAEGQATSDMSARAAR
CCCCCCCCCCCCCCHHCCHHHHHHHHCCCHHHHHHHCCCCHHEEEECCCCCCCHHHHHHH
IALDKAGVKPEELDLIVVATTSPDLLLPSTAALVQTKLGAINAGVMDMNAACCGFLYALS
HHHHHCCCCCCCEEEEEEEECCCCEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
AVTAMIRGGGVGKVLLCGAETISPFLNWQDRNTCVIFGDAAGAVILEATEQERGLQSYKL
HHHHHHHCCCCCEEEEECCHHHHHHCCCCCCCEEEEEECCCCEEEEEECHHHCCHHHEEC
GAIPDTAELLWIKAGATLYPATHERLDQSEQYIQMNGSEVFKHAVRSMVDSSLHVLNQVG
CCCCCCCEEEEEECCCEECCCHHHHHCCCHHHEECCHHHHHHHHHHHHHHHHHHHHHHHC
KTPADVQLVVPHQANLRIIEAVAKRLNVSMDQVFVNIQEYGNTSAATLPVAIAEAADAGR
CCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHEEEHHHCCCCCCCEEEEEEEHHCCCCC
MQPGDTILLTAFGGGLTWASGVLVWGGK
CCCCCEEEEEECCCCCHHHCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA