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The map label for this gene is ygcA [C]

Identifier: 159897144

GI number: 159897144

Start: 708205

End: 709476

Strand: Direct

Name: ygcA [C]

Synonym: Haur_0615

Alternate gene names: 159897144

Gene position: 708205-709476 (Clockwise)

Preceding gene: 159897143

Following gene: 159897145

Centisome position: 11.16

GC content: 54.4

Gene sequence:

>1272_bases
ATGAGCGATTTCGAATGGCCGCCAGAGCTTGACACCACGATTGATGGTTTGGCCCAAGGCGGCGATGGAGTTGGCCGCTA
TGCTGGCCGACCGGTGTTTGTGGCGGCGGCTTTGCCTGGCGAACAGGTGAGGGTGCGCCTCACCGAGCGCCGTAATGGCT
GGGCACGCGGGGTTTTACTGGAGCCACCAAGCAATCCGGCAGCTGAACGGGTTACTCCGGCGTGTCCGGTTTATCAACGC
TGTGGTGGCTGCGATTGGCAATATCAGATGATTGAAAGCCAGCGCCAAGCCAAACAAACGATTTTGGCTGAGCAATTGCG
CTTTGTGGCCCAAACCGATCACGCCGAAGTTGCGGCCACGGCGGCAGGCGAACCATGGCATTATCGTTCGGTTGCGCGGG
TGCATGTCGATGGTCAACGAGTGGGGTTTTATGCCGCTGGTGGTCGCCAGATTGTCGAATTTGATCAGTGCTTGATCATT
GATCCGCGCTTGAATGCGACGATTGAACGATTAAAACCACTGTTGCCTTTGATAGGCTTGCGCGAAATTAGCCTGCGCCT
GAGCACCACCGATGGCACAATCCACGGTCATTTGATTGGGCAAGGCCAAAGTGCTTGGCGTAGTTGGGCACGGCGTTGGA
TGTCAGCAGATGCCACGATTGCTGGAGTTTCTTCGGCGACCCGCGAGGGCTGGATGGCCTTGGCGGGAGCCGAATACTTG
TATGAGCAATTGGGCGATGTACGTTTGCGAATTGCCCCAACCAGCTTTTTTCAAGCTAATGTTGAGCGAGCGCGGGCAGT
GTTGCAGCAAATCGAGTGCTTCTTGCCGTTGAATAACACCACCCGTTTACTTGATGGCTTTTGTGGCGTTGGTACGTTTT
TGTTGCCTTTGGCACATAACATTGGCCATGGCTGGGGCATTGAGGAACATCCGGCGGCAATTCGCGATGCTCAGGCGAGT
GCTAAAGCCAATCAACTTAGTAATGTGACCCTGAAAACCGGCAAGGTTGAGGCGATTTTGCCGCAGCTCAAGCAACAATT
TGATTTAGCGATTGTTGATCCGCCACGGCGTGGAGTCGAGCCAGCTGCCCTCAATGCCCTGATTGCTGCCCAACCAACTA
TGATTGCCTATGTGTCCTGTCATCCTGGCACCTTGGCTCGCGATATTAAGCTTTTGCAGGCTGGCGGTTATACCATTCAG
CATGCTCAGCCCCACGATTTCTTTCCGCAAACCAGCCATGTTGAGAGTTTGGTTTTGCTCAGTAAGGCTTGA

Upstream 100 bases:

>100_bases
CAGGTATCATCGCCATCGCAATCAAACCGCATAACCAGCACATGGCTTCGATTGATGAAGATGGAAACTTATTAATTTGG
GACATCATGAAAGTAGTACA

Downstream 100 bases:

>100_bases
TGAGCCTTCGCCCGATCCCTACCAAACGCCCCTCGCCCGCCGCAGTGGGAGAGGGGTTGGGGTGAGGGAGCCTAAAACCG
ACCCTTGTATGCTCCTAAAC

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MSDFEWPPELDTTIDGLAQGGDGVGRYAGRPVFVAAALPGEQVRVRLTERRNGWARGVLLEPPSNPAAERVTPACPVYQR
CGGCDWQYQMIESQRQAKQTILAEQLRFVAQTDHAEVAATAAGEPWHYRSVARVHVDGQRVGFYAAGGRQIVEFDQCLII
DPRLNATIERLKPLLPLIGLREISLRLSTTDGTIHGHLIGQGQSAWRSWARRWMSADATIAGVSSATREGWMALAGAEYL
YEQLGDVRLRIAPTSFFQANVERARAVLQQIECFLPLNNTTRLLDGFCGVGTFLLPLAHNIGHGWGIEEHPAAIRDAQAS
AKANQLSNVTLKTGKVEAILPQLKQQFDLAIVDPPRRGVEPAALNALIAAQPTMIAYVSCHPGTLARDIKLLQAGGYTIQ
HAQPHDFFPQTSHVESLVLLSKA

Sequences:

>Translated_423_residues
MSDFEWPPELDTTIDGLAQGGDGVGRYAGRPVFVAAALPGEQVRVRLTERRNGWARGVLLEPPSNPAAERVTPACPVYQR
CGGCDWQYQMIESQRQAKQTILAEQLRFVAQTDHAEVAATAAGEPWHYRSVARVHVDGQRVGFYAAGGRQIVEFDQCLII
DPRLNATIERLKPLLPLIGLREISLRLSTTDGTIHGHLIGQGQSAWRSWARRWMSADATIAGVSSATREGWMALAGAEYL
YEQLGDVRLRIAPTSFFQANVERARAVLQQIECFLPLNNTTRLLDGFCGVGTFLLPLAHNIGHGWGIEEHPAAIRDAQAS
AKANQLSNVTLKTGKVEAILPQLKQQFDLAIVDPPRRGVEPAALNALIAAQPTMIAYVSCHPGTLARDIKLLQAGGYTIQ
HAQPHDFFPQTSHVESLVLLSKA
>Mature_422_residues
SDFEWPPELDTTIDGLAQGGDGVGRYAGRPVFVAAALPGEQVRVRLTERRNGWARGVLLEPPSNPAAERVTPACPVYQRC
GGCDWQYQMIESQRQAKQTILAEQLRFVAQTDHAEVAATAAGEPWHYRSVARVHVDGQRVGFYAAGGRQIVEFDQCLIID
PRLNATIERLKPLLPLIGLREISLRLSTTDGTIHGHLIGQGQSAWRSWARRWMSADATIAGVSSATREGWMALAGAEYLY
EQLGDVRLRIAPTSFFQANVERARAVLQQIECFLPLNNTTRLLDGFCGVGTFLLPLAHNIGHGWGIEEHPAAIRDAQASA
KANQLSNVTLKTGKVEAILPQLKQQFDLAIVDPPRRGVEPAALNALIAAQPTMIAYVSCHPGTLARDIKLLQAGGYTIQH
AQPHDFFPQTSHVESLVLLSKA

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=202, Percent_Identity=32.6732673267327, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI51173878, Length=202, Percent_Identity=32.6732673267327, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI269784678, Length=210, Percent_Identity=31.4285714285714, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI269784680, Length=210, Percent_Identity=31.4285714285714, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI269784676, Length=210, Percent_Identity=31.4285714285714, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI20149688, Length=210, Percent_Identity=31.4285714285714, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1789148, Length=428, Percent_Identity=30.8411214953271, Blast_Score=188, Evalue=5e-49,
Organism=Escherichia coli, GI1787083, Length=378, Percent_Identity=27.5132275132275, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1790403, Length=207, Percent_Identity=28.5024154589372, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24666579, Length=210, Percent_Identity=29.0476190476191, Blast_Score=96, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280 [H]

Pfam domain/function: PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 46308; Mature: 46177

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS50926 TRAM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFEWPPELDTTIDGLAQGGDGVGRYAGRPVFVAAALPGEQVRVRLTERRNGWARGVLL
CCCCCCCCCCCHHHHHHHCCCCCCHHCCCCCEEEEEECCCCEEEEEEECCCCCCCCCEEE
EPPSNPAAERVTPACPVYQRCGGCDWQYQMIESQRQAKQTILAEQLRFVAQTDHAEVAAT
CCCCCCHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
AAGEPWHYRSVARVHVDGQRVGFYAAGGRQIVEFDQCLIIDPRLNATIERLKPLLPLIGL
CCCCCCCCCCEEEEEECCCEEEEEECCCCEEEEECCEEEECCCCCHHHHHHHHHHHHCCC
REISLRLSTTDGTIHGHLIGQGQSAWRSWARRWMSADATIAGVSSATREGWMALAGAEYL
EEEEEEEECCCCEEEEEEEECCHHHHHHHHHHHHCCCCEEECCCHHHHCCCEEHHHHHHH
YEQLGDVRLRIAPTSFFQANVERARAVLQQIECFLPLNNTTRLLDGFCGVGTFLLPLAHN
HHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHH
IGHGWGIEEHPAAIRDAQASAKANQLSNVTLKTGKVEAILPQLKQQFDLAIVDPPRRGVE
CCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHCCEEEECCCCCCCC
PAALNALIAAQPTMIAYVSCHPGTLARDIKLLQAGGYTIQHAQPHDFFPQTSHVESLVLL
HHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHEEEE
SKA
ECC
>Mature Secondary Structure 
SDFEWPPELDTTIDGLAQGGDGVGRYAGRPVFVAAALPGEQVRVRLTERRNGWARGVLL
CCCCCCCCCCHHHHHHHCCCCCCHHCCCCCEEEEEECCCCEEEEEEECCCCCCCCCEEE
EPPSNPAAERVTPACPVYQRCGGCDWQYQMIESQRQAKQTILAEQLRFVAQTDHAEVAAT
CCCCCCHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
AAGEPWHYRSVARVHVDGQRVGFYAAGGRQIVEFDQCLIIDPRLNATIERLKPLLPLIGL
CCCCCCCCCCEEEEEECCCEEEEEECCCCEEEEECCEEEECCCCCHHHHHHHHHHHHCCC
REISLRLSTTDGTIHGHLIGQGQSAWRSWARRWMSADATIAGVSSATREGWMALAGAEYL
EEEEEEEECCCCEEEEEEEECCHHHHHHHHHHHHCCCCEEECCCHHHHCCCEEHHHHHHH
YEQLGDVRLRIAPTSFFQANVERARAVLQQIECFLPLNNTTRLLDGFCGVGTFLLPLAHN
HHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHH
IGHGWGIEEHPAAIRDAQASAKANQLSNVTLKTGKVEAILPQLKQQFDLAIVDPPRRGVE
CCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHCCEEEECCCCCCCC
PAALNALIAAQPTMIAYVSCHPGTLARDIKLLQAGGYTIQHAQPHDFFPQTSHVESLVLL
HHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHEEEE
SKA
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]