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The map label for this gene is luxQ [H]

Identifier: 159897135

GI number: 159897135

Start: 696810

End: 699167

Strand: Direct

Name: luxQ [H]

Synonym: Haur_0606

Alternate gene names: 159897135

Gene position: 696810-699167 (Clockwise)

Preceding gene: 159897134

Following gene: 159897137

Centisome position: 10.98

GC content: 47.29

Gene sequence:

>2358_bases
ATGCACTGGCAAATTCCATCGTATACCTTTCCCACCTTGATTGCGAGCAGCGTTTCGTTTGCAATCGCAATTATTGTCTC
ACGTCGCCGCTTTGTTTCACAGATGTGGCCGTTTGCTATTTTAGCTTTCACTGTTGCTTTTTGGACATTGGGCTATGCAT
GGGAATTGGTCAGTGTTGATTTAGCGACTAAAGTTATTTTTGCTAAAACTCAATATTTAGGCATTGCTACGCCACCAGTC
GCTTGGGTGGCGTATGCTTTATATTACACCGGACAAGAGCGTTTTGTCACTAAGCGTAGTTTTTTATATGCCATGATTAT
TCCTGCAATTACCATTGTTTTAGTCTGGACGAATGAATGGCATCATTTGATTTGGACAAAAACTGAAATTGCGATGTATG
GCGAATATACGATGCTCCAAACTTATTATGGACCATGGTTTTGGGTGCATACGGCTTATTCATATGTGTTTATGGCGGCT
GGTACGTTAATTTTGCTGCAAGCATTAGTACTTTCTTCATCGCTTTATCAAAATCAAATTATTGCCTTAATTTTAAGTGC
AATCGCGCCATGGGTCACCAATGCGTTTCATATTTTAGGCTATCGGCCATTTCCCTATCTTGATTTAACCCCGTTTGGCT
TTGTGATTAGCACCGTTGCCTTGGCGTGGGGGGCTTTGCGCTATCGTTTGTTCGATACGATTCCAATTGCGCGGCATATT
TTGATGGAAAATCTCAGTGAGGGCGTGATTTTTCTCGATGCTAAGCGCCGCGTGATGGATATGAACGCCACGGCTGGCAA
GTTGTTGGATATTCGGCCCGACCAGCAAATTGGTCAATCGGCCATCGTCAGCATTTTAGAACGTTTGGATGCACCGCAAT
CGGATGATTCTGATGAGCATTTGCGTTGGGAATATACGCTCCATCGCGATGAGAAAAAATTAGTGCTCGATGTGCAATTA
TCGCCACTGAGCGATCGCAATCGCTATCTTGGCCATTTGCTGTTGCTACGCGATATTACTGAGCGCCATCAGTACGAAGA
TTTGCTGCGCTCGCAACGTAATTTGTTTGCCGGCTTGGTTGAAGTGGCCCGCGCCACCAGCGCTCAGATTGATCTCGACC
AGACCTTGCAAAGCACCTTGGATGTGGCGCTCCACCTAACCACAGCCGAGCAAGGCAGTATTTTTCTGCTCGACCAACAT
CAAATGGTGACTCATAGCATTTTGGCCCGCGAAAAAGCCACGCGCATCGAACAGCAAAATTTGGTTGGGCGGGTGATGCG
CCAAGGCTTGGCAGGCTGGATCGTCGCCCACAATCAAATTGCCTTGATCAAAGACACCCACACTGATGATCGTTGGTTGC
ATTTGCCAAACGCACCCTACAATGCGCGTTCGGTGTTGGCCTTGCCGATTTTTGGCACGGCTGGAATTTTGGGTATTTTG
ATGCTGTTGCATTCAGAGGTTGATCATTTTCGCCAGGAGCATTCCGAGTTGATGGAAGCGGCTACCGCTCAAATTTCGTT
TGCAATTGGCAACGCCCATGTGTACCAAACCCAGCAACAACTGACTCGCGAGCTAAGCCGCGCCAAGGATGCTGCCGAGG
CTGCTAGCCAAACCAAAAGCCAATTTTTGGCCAATATGAGCCACGAATTACGCACCCCGCTTACCGCGATTATTGGCTAT
GCCGATGTGATGCGCGAAGATTTACTCGATTCCAACGACCAAATTTATTTAGCCGACTTGGATCGGATTCGCTCAGCCGG
AGCGCATTTGTTGGGCTTAATCAACGATGTGCTTGATCTCTCGAAAATTGAGGCAGGCAAAATGCCAGTCTATTGGGAGC
AAACCCGCGTCAGCATTCTATTAAATGATGTGATTACGACGGTGCGCCCACAGATTGACCGCAACCATAATAGCCTGATG
ATCGACCAGACCTACCATAACCTGATGTTTTGGACCGATATTTCTAAGTTGCGGCGGGTGTTGATTAATTTGTTGGGCAA
TGCGGCCAAATTCACTGACCATGGCACGATTTCGCTCTCGCTTTTTCTTGATGAAACCGATGAGCCTGCTTGTTTGCAAA
TACGGGTTTGCGATACAGGCATTGGGATGACGGCTGAGCAAGTTGCCAATTTGTTTCAAAATTTTAGCCAAGCCGATGCC
TCAACAACGCGTAAATATGGCGGCACTGGGCTTGGCTTGGCGATTAGTCGTAATCTGTGCAAATTAATGGGCGGCGATAT
TGAAGTGACCAGCGAGTTAGGCCATGGCTCAACTTTTATTGTCAAGTTGCCATGGGTCGAGCAACCATTTAGCGATCAGC
GTGAAGTTGGTTCCGACGGACCACCCTACCTGTTTTGA

Upstream 100 bases:

>100_bases
TTAGTTTGCAGCCACGCCATGGGGTCGAAATGAAACATCTCGGCACACGCACGACCTATATTCTTAATCGCCATCGGCAT
CATTAAGCTTAGGAATTGTT

Downstream 100 bases:

>100_bases
TCACGATGGCGACTGGATTTGTGCCAAACTTATAGCCGATATGGCGTTCGTCGGGCAGGTTGAGCAAGGCCAGATCAGCT
TGCATGCCAACTGCTAAGCT

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 785; Mature: 785

Protein sequence:

>785_residues
MHWQIPSYTFPTLIASSVSFAIAIIVSRRRFVSQMWPFAILAFTVAFWTLGYAWELVSVDLATKVIFAKTQYLGIATPPV
AWVAYALYYTGQERFVTKRSFLYAMIIPAITIVLVWTNEWHHLIWTKTEIAMYGEYTMLQTYYGPWFWVHTAYSYVFMAA
GTLILLQALVLSSSLYQNQIIALILSAIAPWVTNAFHILGYRPFPYLDLTPFGFVISTVALAWGALRYRLFDTIPIARHI
LMENLSEGVIFLDAKRRVMDMNATAGKLLDIRPDQQIGQSAIVSILERLDAPQSDDSDEHLRWEYTLHRDEKKLVLDVQL
SPLSDRNRYLGHLLLLRDITERHQYEDLLRSQRNLFAGLVEVARATSAQIDLDQTLQSTLDVALHLTTAEQGSIFLLDQH
QMVTHSILAREKATRIEQQNLVGRVMRQGLAGWIVAHNQIALIKDTHTDDRWLHLPNAPYNARSVLALPIFGTAGILGIL
MLLHSEVDHFRQEHSELMEAATAQISFAIGNAHVYQTQQQLTRELSRAKDAAEAASQTKSQFLANMSHELRTPLTAIIGY
ADVMREDLLDSNDQIYLADLDRIRSAGAHLLGLINDVLDLSKIEAGKMPVYWEQTRVSILLNDVITTVRPQIDRNHNSLM
IDQTYHNLMFWTDISKLRRVLINLLGNAAKFTDHGTISLSLFLDETDEPACLQIRVCDTGIGMTAEQVANLFQNFSQADA
STTRKYGGTGLGLAISRNLCKLMGGDIEVTSELGHGSTFIVKLPWVEQPFSDQREVGSDGPPYLF

Sequences:

>Translated_785_residues
MHWQIPSYTFPTLIASSVSFAIAIIVSRRRFVSQMWPFAILAFTVAFWTLGYAWELVSVDLATKVIFAKTQYLGIATPPV
AWVAYALYYTGQERFVTKRSFLYAMIIPAITIVLVWTNEWHHLIWTKTEIAMYGEYTMLQTYYGPWFWVHTAYSYVFMAA
GTLILLQALVLSSSLYQNQIIALILSAIAPWVTNAFHILGYRPFPYLDLTPFGFVISTVALAWGALRYRLFDTIPIARHI
LMENLSEGVIFLDAKRRVMDMNATAGKLLDIRPDQQIGQSAIVSILERLDAPQSDDSDEHLRWEYTLHRDEKKLVLDVQL
SPLSDRNRYLGHLLLLRDITERHQYEDLLRSQRNLFAGLVEVARATSAQIDLDQTLQSTLDVALHLTTAEQGSIFLLDQH
QMVTHSILAREKATRIEQQNLVGRVMRQGLAGWIVAHNQIALIKDTHTDDRWLHLPNAPYNARSVLALPIFGTAGILGIL
MLLHSEVDHFRQEHSELMEAATAQISFAIGNAHVYQTQQQLTRELSRAKDAAEAASQTKSQFLANMSHELRTPLTAIIGY
ADVMREDLLDSNDQIYLADLDRIRSAGAHLLGLINDVLDLSKIEAGKMPVYWEQTRVSILLNDVITTVRPQIDRNHNSLM
IDQTYHNLMFWTDISKLRRVLINLLGNAAKFTDHGTISLSLFLDETDEPACLQIRVCDTGIGMTAEQVANLFQNFSQADA
STTRKYGGTGLGLAISRNLCKLMGGDIEVTSELGHGSTFIVKLPWVEQPFSDQREVGSDGPPYLF
>Mature_785_residues
MHWQIPSYTFPTLIASSVSFAIAIIVSRRRFVSQMWPFAILAFTVAFWTLGYAWELVSVDLATKVIFAKTQYLGIATPPV
AWVAYALYYTGQERFVTKRSFLYAMIIPAITIVLVWTNEWHHLIWTKTEIAMYGEYTMLQTYYGPWFWVHTAYSYVFMAA
GTLILLQALVLSSSLYQNQIIALILSAIAPWVTNAFHILGYRPFPYLDLTPFGFVISTVALAWGALRYRLFDTIPIARHI
LMENLSEGVIFLDAKRRVMDMNATAGKLLDIRPDQQIGQSAIVSILERLDAPQSDDSDEHLRWEYTLHRDEKKLVLDVQL
SPLSDRNRYLGHLLLLRDITERHQYEDLLRSQRNLFAGLVEVARATSAQIDLDQTLQSTLDVALHLTTAEQGSIFLLDQH
QMVTHSILAREKATRIEQQNLVGRVMRQGLAGWIVAHNQIALIKDTHTDDRWLHLPNAPYNARSVLALPIFGTAGILGIL
MLLHSEVDHFRQEHSELMEAATAQISFAIGNAHVYQTQQQLTRELSRAKDAAEAASQTKSQFLANMSHELRTPLTAIIGY
ADVMREDLLDSNDQIYLADLDRIRSAGAHLLGLINDVLDLSKIEAGKMPVYWEQTRVSILLNDVITTVRPQIDRNHNSLM
IDQTYHNLMFWTDISKLRRVLINLLGNAAKFTDHGTISLSLFLDETDEPACLQIRVCDTGIGMTAEQVANLFQNFSQADA
STTRKYGGTGLGLAISRNLCKLMGGDIEVTSELGHGSTFIVKLPWVEQPFSDQREVGSDGPPYLF

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=244, Percent_Identity=39.7540983606557, Blast_Score=149, Evalue=9e-37,
Organism=Escherichia coli, GI145693157, Length=247, Percent_Identity=38.0566801619433, Blast_Score=146, Evalue=5e-36,
Organism=Escherichia coli, GI48994928, Length=255, Percent_Identity=34.1176470588235, Blast_Score=133, Evalue=5e-32,
Organism=Escherichia coli, GI1788713, Length=249, Percent_Identity=32.5301204819277, Blast_Score=127, Evalue=4e-30,
Organism=Escherichia coli, GI87081816, Length=253, Percent_Identity=37.9446640316205, Blast_Score=126, Evalue=5e-30,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=29.5154185022026, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786912, Length=346, Percent_Identity=26.3005780346821, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1790436, Length=230, Percent_Identity=29.1304347826087, Blast_Score=78, Evalue=3e-15,
Organism=Escherichia coli, GI1788393, Length=257, Percent_Identity=24.9027237354086, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788549, Length=247, Percent_Identity=27.5303643724696, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787894, Length=253, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1790346, Length=234, Percent_Identity=25.6410256410256, Blast_Score=73, Evalue=9e-14,
Organism=Escherichia coli, GI1790861, Length=229, Percent_Identity=25.764192139738, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=25.764192139738, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88728; Mature: 88728

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN ; PS00133 CARBOXYPEPT_ZN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHWQIPSYTFPTLIASSVSFAIAIIVSRRRFVSQMWPFAILAFTVAFWTLGYAWELVSVD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATKVIFAKTQYLGIATPPVAWVAYALYYTGQERFVTKRSFLYAMIIPAITIVLVWTNEW
HHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEEECCC
HHLIWTKTEIAMYGEYTMLQTYYGPWFWVHTAYSYVFMAAGTLILLQALVLSSSLYQNQI
CEEEEEEEEEEEECCEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALILSAIAPWVTNAFHILGYRPFPYLDLTPFGFVISTVALAWGALRYRLFDTIPIARHI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMENLSEGVIFLDAKRRVMDMNATAGKLLDIRPDQQIGQSAIVSILERLDAPQSDDSDEH
HHHHHCCCEEEEECCCCEEECCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
LRWEYTLHRDEKKLVLDVQLSPLSDRNRYLGHLLLLRDITERHQYEDLLRSQRNLFAGLV
EEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVARATSAQIDLDQTLQSTLDVALHLTTAEQGSIFLLDQHQMVTHSILAREKATRIEQQN
HHHHHCCCCCCHHHHHHHHHHEEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHH
LVGRVMRQGLAGWIVAHNQIALIKDTHTDDRWLHLPNAPYNARSVLALPIFGTAGILGIL
HHHHHHHHCCCEEEEECCEEEEEEECCCCCCEEECCCCCCCCCEEEEEECCCHHHHHHHH
MLLHSEVDHFRQEHSELMEAATAQISFAIGNAHVYQTQQQLTRELSRAKDAAEAASQTKS
HHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFLANMSHELRTPLTAIIGYADVMREDLLDSNDQIYLADLDRIRSAGAHLLGLINDVLDL
HHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
SKIEAGKMPVYWEQTRVSILLNDVITTVRPQIDRNHNSLMIDQTYHNLMFWTDISKLRRV
HHCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHEEEEHHHHHHHHH
LINLLGNAAKFTDHGTISLSLFLDETDEPACLQIRVCDTGIGMTAEQVANLFQNFSQADA
HHHHHCCCCEECCCCEEEEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCH
STTRKYGGTGLGLAISRNLCKLMGGDIEVTSELGHGSTFIVKLPWVEQPFSDQREVGSDG
HHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCCCCCCCHHHCCCCC
PPYLF
CCCCC
>Mature Secondary Structure
MHWQIPSYTFPTLIASSVSFAIAIIVSRRRFVSQMWPFAILAFTVAFWTLGYAWELVSVD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATKVIFAKTQYLGIATPPVAWVAYALYYTGQERFVTKRSFLYAMIIPAITIVLVWTNEW
HHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEEECCC
HHLIWTKTEIAMYGEYTMLQTYYGPWFWVHTAYSYVFMAAGTLILLQALVLSSSLYQNQI
CEEEEEEEEEEEECCEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALILSAIAPWVTNAFHILGYRPFPYLDLTPFGFVISTVALAWGALRYRLFDTIPIARHI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMENLSEGVIFLDAKRRVMDMNATAGKLLDIRPDQQIGQSAIVSILERLDAPQSDDSDEH
HHHHHCCCEEEEECCCCEEECCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
LRWEYTLHRDEKKLVLDVQLSPLSDRNRYLGHLLLLRDITERHQYEDLLRSQRNLFAGLV
EEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVARATSAQIDLDQTLQSTLDVALHLTTAEQGSIFLLDQHQMVTHSILAREKATRIEQQN
HHHHHCCCCCCHHHHHHHHHHEEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHH
LVGRVMRQGLAGWIVAHNQIALIKDTHTDDRWLHLPNAPYNARSVLALPIFGTAGILGIL
HHHHHHHHCCCEEEEECCEEEEEEECCCCCCEEECCCCCCCCCEEEEEECCCHHHHHHHH
MLLHSEVDHFRQEHSELMEAATAQISFAIGNAHVYQTQQQLTRELSRAKDAAEAASQTKS
HHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFLANMSHELRTPLTAIIGYADVMREDLLDSNDQIYLADLDRIRSAGAHLLGLINDVLDL
HHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
SKIEAGKMPVYWEQTRVSILLNDVITTVRPQIDRNHNSLMIDQTYHNLMFWTDISKLRRV
HHCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHEEEEHHHHHHHHH
LINLLGNAAKFTDHGTISLSLFLDETDEPACLQIRVCDTGIGMTAEQVANLFQNFSQADA
HHHHHCCCCEECCCCEEEEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCH
STTRKYGGTGLGLAISRNLCKLMGGDIEVTSELGHGSTFIVKLPWVEQPFSDQREVGSDG
HHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCCCCCCCHHHCCCCC
PPYLF
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA