Click here to switch to the map view.

The map label for this gene is ytfL [C]

Identifier: 159897002

GI number: 159897002

Start: 549987

End: 551285

Strand: Direct

Name: ytfL [C]

Synonym: Haur_0470

Alternate gene names: 159897002

Gene position: 549987-551285 (Clockwise)

Preceding gene: 159896998

Following gene: 159897003

Centisome position: 8.67

GC content: 49.04

Gene sequence:

>1299_bases
ATGCTAAGTGACATAGCCAGCGAGCTAGGAATTGTCTTGGTATTGCTGGTTGCCAACGGGGTTTTTGCTGCATCGGAGCT
AGCCATGGTTTCGGCGCGGCGTTCTCGCTTAGAACAACAAGCCGCCGATGGCGATCTTCGGGCAAAGAAAGCCCTGCAAC
TCGCCGACCAACCTGATCGTTTATTAGCCACGGTTCAAGTTGGCATCACATTAATTGGTACGTTTGCAGCAGCTTTTGGG
GGTGCTAACATTAGCAAGCCCTTTGCCGAATACCTAAAAACGGTTCCTGCGCTCGCTCCCTATGCCGATTCAATTGCATT
TACGGTGGTTGTATTGCTCATCACCTATCTTTCGTTGATTATTGGTGAGCTTGTGCCCAAACGCTTAGCATTGCTGCATG
CCGATGCGATTGCCCGTAATTTAGCGCCGCTGCTGGCTTGGCTTTCGTGGCTAACCCGGCCAATTGTCTGGGTCTTGACC
ACCTCATCGACAGTGATTCTGACGTTAATTGGCCAAAACAAAAAACCCGATTCTAGCGTAACCGAAGATGATATTTTGTA
TATGACTCGCGAAGGTCGGGCTGGCGGCACGGTCGCCTTGCACGAAGAGGCCTTGATCTCACGGGTATTTGATTTTTCGG
ATCGTACAGCCCGCATGTTGATGACCCCACGGCCTGATGTTGTAGCGGTCAGTGCTAACACTCCCTTGGACGAAATTACG
CGGATTGCGGTTGAACATGGCTATTCACGCATGCCAGTTTACGAAGGTGATTCGCTAGATCGAGCAATTGGGACGATCTA
TATTAAAGATGTGTTGCCTTCAATGTTGGGCAACGATCAACGCCAATTGCGTGAATTGGTGCGCCCGCCAACGTATGTAT
TGGAGCACGAACCAGTTTCCAAGATGTTGACCCTGTTTCGGCGCACTGGCTCACACATGGCCTTGGTTGTCGATGAATAT
GGCCAAATTGCTGGAATTTTAACCCTCGAAGATGTGCTTGAAGAATTGGTTGGCGATATTCGCGATGAATATGACTCCAA
CGAAGAACAAACCATGGTCAAACGTGATGATGGCTCATGGCTGATCGACGGCTCGGAATCATACGAAGTGATTGCAACCC
GCTTGAGTATTCCAATTAATGATGATAACGACTTTGTGACGATTGCTGGCTATGTGTTGAACGAACTGCATCGGTTGCCC
AACGTTGGCGATCATGTAACTTGGGATGAATACGATGTCGAAGTGATCGATATGGATGGTCGGCGGATTGATAAGGTGTT
GATCAAAAAACGCGCCTAA

Upstream 100 bases:

>100_bases
GTGGGAGAGGGGTTGGGGTGAGGGCAGGCACTACATTGCAAACCGAATAAACTATTATCCATACGCTGTAGCTATTCTAG
TTTGAGAAAGGAACAATTGA

Downstream 100 bases:

>100_bases
ACTGCTGAATCGACAATCGAGCAATGACGAAGCTCCTTGGAGTTTCGTCATTGTTGTTAATCGGCCTAGATTTGAGGTGT
TATGCTTGATTTAGCCAGTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MLSDIASELGIVLVLLVANGVFAASELAMVSARRSRLEQQAADGDLRAKKALQLADQPDRLLATVQVGITLIGTFAAAFG
GANISKPFAEYLKTVPALAPYADSIAFTVVVLLITYLSLIIGELVPKRLALLHADAIARNLAPLLAWLSWLTRPIVWVLT
TSSTVILTLIGQNKKPDSSVTEDDILYMTREGRAGGTVALHEEALISRVFDFSDRTARMLMTPRPDVVAVSANTPLDEIT
RIAVEHGYSRMPVYEGDSLDRAIGTIYIKDVLPSMLGNDQRQLRELVRPPTYVLEHEPVSKMLTLFRRTGSHMALVVDEY
GQIAGILTLEDVLEELVGDIRDEYDSNEEQTMVKRDDGSWLIDGSESYEVIATRLSIPINDDNDFVTIAGYVLNELHRLP
NVGDHVTWDEYDVEVIDMDGRRIDKVLIKKRA

Sequences:

>Translated_432_residues
MLSDIASELGIVLVLLVANGVFAASELAMVSARRSRLEQQAADGDLRAKKALQLADQPDRLLATVQVGITLIGTFAAAFG
GANISKPFAEYLKTVPALAPYADSIAFTVVVLLITYLSLIIGELVPKRLALLHADAIARNLAPLLAWLSWLTRPIVWVLT
TSSTVILTLIGQNKKPDSSVTEDDILYMTREGRAGGTVALHEEALISRVFDFSDRTARMLMTPRPDVVAVSANTPLDEIT
RIAVEHGYSRMPVYEGDSLDRAIGTIYIKDVLPSMLGNDQRQLRELVRPPTYVLEHEPVSKMLTLFRRTGSHMALVVDEY
GQIAGILTLEDVLEELVGDIRDEYDSNEEQTMVKRDDGSWLIDGSESYEVIATRLSIPINDDNDFVTIAGYVLNELHRLP
NVGDHVTWDEYDVEVIDMDGRRIDKVLIKKRA
>Mature_432_residues
MLSDIASELGIVLVLLVANGVFAASELAMVSARRSRLEQQAADGDLRAKKALQLADQPDRLLATVQVGITLIGTFAAAFG
GANISKPFAEYLKTVPALAPYADSIAFTVVVLLITYLSLIIGELVPKRLALLHADAIARNLAPLLAWLSWLTRPIVWVLT
TSSTVILTLIGQNKKPDSSVTEDDILYMTREGRAGGTVALHEEALISRVFDFSDRTARMLMTPRPDVVAVSANTPLDEIT
RIAVEHGYSRMPVYEGDSLDRAIGTIYIKDVLPSMLGNDQRQLRELVRPPTYVLEHEPVSKMLTLFRRTGSHMALVVDEY
GQIAGILTLEDVLEELVGDIRDEYDSNEEQTMVKRDDGSWLIDGSESYEVIATRLSIPINDDNDFVTIAGYVLNELHRLP
NVGDHVTWDEYDVEVIDMDGRRIDKVLIKKRA

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=392, Percent_Identity=29.5918367346939, Blast_Score=195, Evalue=8e-50,
Organism=Homo sapiens, GI40068053, Length=251, Percent_Identity=26.2948207171315, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI40068055, Length=251, Percent_Identity=26.2948207171315, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI94681046, Length=251, Percent_Identity=25.4980079681275, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1790664, Length=423, Percent_Identity=26.241134751773, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI145693175, Length=410, Percent_Identity=27.0731707317073, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI87082033, Length=360, Percent_Identity=26.6666666666667, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1786879, Length=248, Percent_Identity=30.241935483871, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788119, Length=270, Percent_Identity=27.4074074074074, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71980512, Length=377, Percent_Identity=25.4641909814324, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324512, Length=250, Percent_Identity=26.8, Blast_Score=70, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47753; Mature: 47753

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSDIASELGIVLVLLVANGVFAASELAMVSARRSRLEQQAADGDLRAKKALQLADQPDR
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHH
LLATVQVGITLIGTFAAAFGGANISKPFAEYLKTVPALAPYADSIAFTVVVLLITYLSLI
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
IGELVPKRLALLHADAIARNLAPLLAWLSWLTRPIVWVLTTSSTVILTLIGQNKKPDSSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEEEECCCCCCCCCC
TEDDILYMTREGRAGGTVALHEEALISRVFDFSDRTARMLMTPRPDVVAVSANTPLDEIT
CCCCEEEEEECCCCCCEEEEHHHHHHHHHHCCCCCCHHEEECCCCCEEEEECCCCHHHHH
RIAVEHGYSRMPVYEGDSLDRAIGTIYIKDVLPSMLGNDQRQLRELVRPPTYVLEHEPVS
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEECCCCHH
KMLTLFRRTGSHMALVVDEYGQIAGILTLEDVLEELVGDIRDEYDSNEEQTMVKRDDGSW
HHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCE
LIDGSESYEVIATRLSIPINDDNDFVTIAGYVLNELHRLPNVGDHVTWDEYDVEVIDMDG
EEECCCCCEEEEEEEEEEECCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCC
RRIDKVLIKKRA
HHHHHHHHHCCC
>Mature Secondary Structure
MLSDIASELGIVLVLLVANGVFAASELAMVSARRSRLEQQAADGDLRAKKALQLADQPDR
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHH
LLATVQVGITLIGTFAAAFGGANISKPFAEYLKTVPALAPYADSIAFTVVVLLITYLSLI
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
IGELVPKRLALLHADAIARNLAPLLAWLSWLTRPIVWVLTTSSTVILTLIGQNKKPDSSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEEEECCCCCCCCCC
TEDDILYMTREGRAGGTVALHEEALISRVFDFSDRTARMLMTPRPDVVAVSANTPLDEIT
CCCCEEEEEECCCCCCEEEEHHHHHHHHHHCCCCCCHHEEECCCCCEEEEECCCCHHHHH
RIAVEHGYSRMPVYEGDSLDRAIGTIYIKDVLPSMLGNDQRQLRELVRPPTYVLEHEPVS
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEECCCCHH
KMLTLFRRTGSHMALVVDEYGQIAGILTLEDVLEELVGDIRDEYDSNEEQTMVKRDDGSW
HHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCE
LIDGSESYEVIATRLSIPINDDNDFVTIAGYVLNELHRLPNVGDHVTWDEYDVEVIDMDG
EEECCCCCEEEEEEEEEEECCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCC
RRIDKVLIKKRA
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]