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The map label for this gene is rsbRA [H]

Identifier: 159896983

GI number: 159896983

Start: 528277

End: 529215

Strand: Direct

Name: rsbRA [H]

Synonym: Haur_0451

Alternate gene names: 159896983

Gene position: 528277-529215 (Clockwise)

Preceding gene: 159896981

Following gene: 159896988

Centisome position: 8.32

GC content: 49.63

Gene sequence:

>939_bases
ATGTCCTTAGGATCAGGATCACAGCTGAACAATGCTGAACGAACCGAGACATTGCAAGAGCTTGGGCTGCTTGATGTTTC
TTTCGACCCAGCTTTTGATCGTTTGACCCGCTTAGCAAGCAAGGTTTTGCAAGCACCAGTGTCGTTACTTTCGCTCGTTG
AACATCATCGGCAATATTTTAAAAGCCATATTGGGTTGGCTGAGCCATGGGCCGAGCGCCGCGAAACCCCATTAACCCAT
TCGTTTTGCCAACATGTGGTCAGCAATGGTCAAGAATTAATTGTGACCGATGCCCGCGAACATCCCTTAGTTCACGATAA
TTTGGCTATCCCCGATTTGGGCGTGATTAGCTATGCAGGTATGCCGATTCGCAGCGGTGGCCATGTACTTGGCTCGTTCT
GTGTGATCGATGGCAAGCCCCGGGTTTGGACGGCTGATGAACTGGATATTCTGCATGAATTTGCTGAATTGTTGATGACC
GAACTCAAACTACGCCAAGAAATTCGTATCCACCAACAGGATATTCGCGAGCGGGAGCGCTTGCAAAACGAGTTGATCGG
CTTGCAACAAGCCTTGCTCGATGAGCTTTCAACCCCGCTGATTCCTTTAAATGATCAGGTATTGGTCGTTCCATTGATTG
GAGCGCTCGATCAGCAGCGTGCGCAACGGATGACCGAGGCGCTATTAACTGGTGTCGGTAAATATCGCGCTGATTTTGTG
ATTCTCGATATTACTGGTGTGCCCGTGCTCGATACCTATGTGGCATCGTTGTTGGTGCAAACCTCGCAAGCAATTCAACT
GCTCGGTGCGCGAATGGTATTAACGGGTTTGCGCCCCGAAATTGCCCAAACCATCGTCAGCGTTGGCCTCGATTTGCGTA
GCGTTGTGACCTATAGCACGCTGCAACAGGGCATCGAATATACCTTTCGGCGTAAATAA

Upstream 100 bases:

>100_bases
TGGTTTTTCCCCCACATGGTTACCCTATCGCGGCCATTGTGGAATGTTAATAACTCTGGTACTGTTTTTAATAACGCTTT
TATTTTGGAGATGCTGGCAT

Downstream 100 bases:

>100_bases
GTTTGTTATTTTTACAATGGCGGAGTTTAACGCTCCGCCATTTCGCACTTAAGCAGTTTTGCGCTTGAATTTGCGTTGCA
ATGCTGCACCGAAAAATTGC

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSLGSGSQLNNAERTETLQELGLLDVSFDPAFDRLTRLASKVLQAPVSLLSLVEHHRQYFKSHIGLAEPWAERRETPLTH
SFCQHVVSNGQELIVTDAREHPLVHDNLAIPDLGVISYAGMPIRSGGHVLGSFCVIDGKPRVWTADELDILHEFAELLMT
ELKLRQEIRIHQQDIRERERLQNELIGLQQALLDELSTPLIPLNDQVLVVPLIGALDQQRAQRMTEALLTGVGKYRADFV
ILDITGVPVLDTYVASLLVQTSQAIQLLGARMVLTGLRPEIAQTIVSVGLDLRSVVTYSTLQQGIEYTFRRK

Sequences:

>Translated_312_residues
MSLGSGSQLNNAERTETLQELGLLDVSFDPAFDRLTRLASKVLQAPVSLLSLVEHHRQYFKSHIGLAEPWAERRETPLTH
SFCQHVVSNGQELIVTDAREHPLVHDNLAIPDLGVISYAGMPIRSGGHVLGSFCVIDGKPRVWTADELDILHEFAELLMT
ELKLRQEIRIHQQDIRERERLQNELIGLQQALLDELSTPLIPLNDQVLVVPLIGALDQQRAQRMTEALLTGVGKYRADFV
ILDITGVPVLDTYVASLLVQTSQAIQLLGARMVLTGLRPEIAQTIVSVGLDLRSVVTYSTLQQGIEYTFRRK
>Mature_311_residues
SLGSGSQLNNAERTETLQELGLLDVSFDPAFDRLTRLASKVLQAPVSLLSLVEHHRQYFKSHIGLAEPWAERRETPLTHS
FCQHVVSNGQELIVTDAREHPLVHDNLAIPDLGVISYAGMPIRSGGHVLGSFCVIDGKPRVWTADELDILHEFAELLMTE
LKLRQEIRIHQQDIRERERLQNELIGLQQALLDELSTPLIPLNDQVLVVPLIGALDQQRAQRMTEALLTGVGKYRADFVI
LDITGVPVLDTYVASLLVQTSQAIQLLGARMVLTGLRPEIAQTIVSVGLDLRSVVTYSTLQQGIEYTFRRK

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 34831; Mature: 34699

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLGSGSQLNNAERTETLQELGLLDVSFDPAFDRLTRLASKVLQAPVSLLSLVEHHRQYF
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSHIGLAEPWAERRETPLTHSFCQHVVSNGQELIVTDAREHPLVHDNLAIPDLGVISYAG
HHHCCCCCCHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHCC
MPIRSGGHVLGSFCVIDGKPRVWTADELDILHEFAELLMTELKLRQEIRIHQQDIRERER
CCCCCCCCEEEEEEEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQNELIGLQQALLDELSTPLIPLNDQVLVVPLIGALDQQRAQRMTEALLTGVGKYRADFV
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
ILDITGVPVLDTYVASLLVQTSQAIQLLGARMVLTGLRPEIAQTIVSVGLDLRSVVTYST
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHH
LQQGIEYTFRRK
HHHHHHHHHCCC
>Mature Secondary Structure 
SLGSGSQLNNAERTETLQELGLLDVSFDPAFDRLTRLASKVLQAPVSLLSLVEHHRQYF
CCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSHIGLAEPWAERRETPLTHSFCQHVVSNGQELIVTDAREHPLVHDNLAIPDLGVISYAG
HHHCCCCCCHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHCC
MPIRSGGHVLGSFCVIDGKPRVWTADELDILHEFAELLMTELKLRQEIRIHQQDIRERER
CCCCCCCCEEEEEEEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQNELIGLQQALLDELSTPLIPLNDQVLVVPLIGALDQQRAQRMTEALLTGVGKYRADFV
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
ILDITGVPVLDTYVASLLVQTSQAIQLLGARMVLTGLRPEIAQTIVSVGLDLRSVVTYST
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHH
LQQGIEYTFRRK
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]