| Definition | Herpetosiphon aurantiacus ATCC 23779 chromosome, complete genome. |
|---|---|
| Accession | NC_009972 |
| Length | 6,346,587 |
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The map label for this gene is yvgN [H]
Identifier: 159896893
GI number: 159896893
Start: 432016
End: 432876
Strand: Direct
Name: yvgN [H]
Synonym: Haur_0361
Alternate gene names: 159896893
Gene position: 432016-432876 (Clockwise)
Preceding gene: 159896891
Following gene: 159896894
Centisome position: 6.81
GC content: 50.41
Gene sequence:
>861_bases ATGACAATCATCCCAACAGTGAGCTTAAATGCGGGTATTGCAATGCCGATCCTCGGGTTTGGTGTGTTTCAGATTACCGA TGCAGCGGAATGCGAACGCGCCGTTAGTGATGCGATTCAGACGGGCTATCGGCTAATTGACACTGCTGCCGTCTATGGCA ATGAAGCAGCGGTTGGAGCCGCGATCGCCCGAAGTGGTGTGGCCCGCGAAGATCTATTCGTGACAACCAAGCTGTGGATT CAGGACACGGGCTACGAGCAGACCAAAGCTGCTTTTGAGCGTTCGCTCCAACGCTTAGGCCTCGATTATCTCGACCTGTA TTTGATTCACCAACCATACGGAGATATTTATGGTGCGTGGCGGGCTATGGAAGAGTTATATCAGGCAGGCCGGATTCGCG CCATTGGGGTCAGCAATTTTCACCCCGATCGGGTAATGGATTTGATCGTTCATAACCAAGTTCCGCCTGCGGTCAACCAG ATTGAAACGCATCCATTCCAGCAGCAAATCGATACTCAACAGTTCTTACAGCAGCAGGGTGTACAGATTGAGTCGTGGGG GCCATTTGCTGAAGGTAAACATGCTATTTTCCAGAATGAGCTACTAGCAGGTATTGCCGCTACCCATCAAAAAACTGTTG CACAGGTGATTCTGCGCTGGTTAACTCAACGTGGGGTTGTGGCAATTCCCAAATCGGTACGCAAAGAACGCATGGAAGAA AACTTCAACGTGTTCGATATTACCCTTAGCCCAGAAGAAATGGCGGCGATTAGCACATTGGATACAAAAACTAGCAGCTT CTTTGACCACCGCGACCCAGCCGTCGTGAAGATGTTAGGTGAAGCAAACCGCCCAACCTAG
Upstream 100 bases:
>100_bases CTATACTTAGTTATGGCACGAAGTAGGCTGATCCAGCGCTCTAGAGAATCGGACAAGTAGGCGCGATTCGTGCTTTTTCA ATAGCTAAGGAGTATCGCTT
Downstream 100 bases:
>100_bases AATACTAATCACATCCAACATCCTCACAGCATTTGGTGGCAACTGCACCAGAATATTCGATCTGCTCGTCTACAAGTGGC TCCATTATGCGAGCCGTTTG
Product: 2,5-didehydrogluconate reductase
Products: NA
Alternate protein names: GR; Methylglyoxal reductase [H]
Number of amino acids: Translated: 286; Mature: 285
Protein sequence:
>286_residues MTIIPTVSLNAGIAMPILGFGVFQITDAAECERAVSDAIQTGYRLIDTAAVYGNEAAVGAAIARSGVAREDLFVTTKLWI QDTGYEQTKAAFERSLQRLGLDYLDLYLIHQPYGDIYGAWRAMEELYQAGRIRAIGVSNFHPDRVMDLIVHNQVPPAVNQ IETHPFQQQIDTQQFLQQQGVQIESWGPFAEGKHAIFQNELLAGIAATHQKTVAQVILRWLTQRGVVAIPKSVRKERMEE NFNVFDITLSPEEMAAISTLDTKTSSFFDHRDPAVVKMLGEANRPT
Sequences:
>Translated_286_residues MTIIPTVSLNAGIAMPILGFGVFQITDAAECERAVSDAIQTGYRLIDTAAVYGNEAAVGAAIARSGVAREDLFVTTKLWI QDTGYEQTKAAFERSLQRLGLDYLDLYLIHQPYGDIYGAWRAMEELYQAGRIRAIGVSNFHPDRVMDLIVHNQVPPAVNQ IETHPFQQQIDTQQFLQQQGVQIESWGPFAEGKHAIFQNELLAGIAATHQKTVAQVILRWLTQRGVVAIPKSVRKERMEE NFNVFDITLSPEEMAAISTLDTKTSSFFDHRDPAVVKMLGEANRPT >Mature_285_residues TIIPTVSLNAGIAMPILGFGVFQITDAAECERAVSDAIQTGYRLIDTAAVYGNEAAVGAAIARSGVAREDLFVTTKLWIQ DTGYEQTKAAFERSLQRLGLDYLDLYLIHQPYGDIYGAWRAMEELYQAGRIRAIGVSNFHPDRVMDLIVHNQVPPAVNQI ETHPFQQQIDTQQFLQQQGVQIESWGPFAEGKHAIFQNELLAGIAATHQKTVAQVILRWLTQRGVVAIPKSVRKERMEEN FNVFDITLSPEEMAAISTLDTKTSSFFDHRDPAVVKMLGEANRPT
Specific function: Reduces glyoxal and methylglyoxal. Is not involved in the vitamin B6 biosynthesis [H]
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldo/keto reductase family [H]
Homologues:
Organism=Homo sapiens, GI24497577, Length=290, Percent_Identity=34.1379310344828, Blast_Score=178, Evalue=5e-45, Organism=Homo sapiens, GI5174391, Length=290, Percent_Identity=34.1379310344828, Blast_Score=178, Evalue=5e-45, Organism=Homo sapiens, GI5174695, Length=295, Percent_Identity=36.271186440678, Blast_Score=177, Evalue=1e-44, Organism=Homo sapiens, GI223468663, Length=292, Percent_Identity=36.986301369863, Blast_Score=175, Evalue=4e-44, Organism=Homo sapiens, GI45446745, Length=297, Percent_Identity=35.016835016835, Blast_Score=172, Evalue=4e-43, Organism=Homo sapiens, GI4503285, Length=297, Percent_Identity=35.016835016835, Blast_Score=172, Evalue=4e-43, Organism=Homo sapiens, GI310109920, Length=297, Percent_Identity=34.6801346801347, Blast_Score=171, Evalue=5e-43, Organism=Homo sapiens, GI310109922, Length=276, Percent_Identity=36.5942028985507, Blast_Score=171, Evalue=6e-43, Organism=Homo sapiens, GI5453543, Length=297, Percent_Identity=34.3434343434343, Blast_Score=169, Evalue=4e-42, Organism=Homo sapiens, GI300116273, Length=278, Percent_Identity=35.9712230215827, Blast_Score=162, Evalue=4e-40, Organism=Homo sapiens, GI24497583, Length=301, Percent_Identity=32.2259136212625, Blast_Score=161, Evalue=6e-40, Organism=Homo sapiens, GI24497585, Length=295, Percent_Identity=32.8813559322034, Blast_Score=159, Evalue=2e-39, Organism=Homo sapiens, GI4502049, Length=285, Percent_Identity=38.5964912280702, Blast_Score=158, Evalue=6e-39, Organism=Homo sapiens, GI291291012, Length=276, Percent_Identity=34.7826086956522, Blast_Score=153, Evalue=2e-37, Organism=Homo sapiens, GI300116271, Length=271, Percent_Identity=34.6863468634686, Blast_Score=152, Evalue=5e-37, Organism=Homo sapiens, GI93277124, Length=296, Percent_Identity=32.4324324324324, Blast_Score=145, Evalue=3e-35, Organism=Homo sapiens, GI207028673, Length=113, Percent_Identity=46.9026548672566, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI310109926, Length=113, Percent_Identity=46.0176991150442, Blast_Score=96, Evalue=5e-20, Organism=Homo sapiens, GI310109924, Length=153, Percent_Identity=31.3725490196078, Blast_Score=86, Evalue=5e-17, Organism=Homo sapiens, GI27436966, Length=241, Percent_Identity=26.9709543568465, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI27436964, Length=241, Percent_Identity=26.9709543568465, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI27436962, Length=241, Percent_Identity=26.9709543568465, Blast_Score=73, Evalue=2e-13, Organism=Escherichia coli, GI87082198, Length=261, Percent_Identity=42.5287356321839, Blast_Score=206, Evalue=2e-54, Organism=Escherichia coli, GI1786400, Length=257, Percent_Identity=37.3540856031128, Blast_Score=162, Evalue=3e-41, Organism=Escherichia coli, GI1788081, Length=269, Percent_Identity=31.2267657992565, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI48994888, Length=223, Percent_Identity=28.6995515695067, Blast_Score=66, Evalue=3e-12, Organism=Caenorhabditis elegans, GI71998625, Length=277, Percent_Identity=36.101083032491, Blast_Score=190, Evalue=6e-49, Organism=Caenorhabditis elegans, GI17564128, Length=302, Percent_Identity=33.4437086092715, Blast_Score=178, Evalue=3e-45, Organism=Caenorhabditis elegans, GI17561298, Length=272, Percent_Identity=32.3529411764706, Blast_Score=168, Evalue=3e-42, Organism=Caenorhabditis elegans, GI17537077, Length=295, Percent_Identity=34.5762711864407, Blast_Score=167, Evalue=5e-42, Organism=Caenorhabditis elegans, GI17550248, Length=284, Percent_Identity=32.7464788732394, Blast_Score=166, Evalue=1e-41, Organism=Caenorhabditis elegans, GI17537075, Length=295, Percent_Identity=34.9152542372881, Blast_Score=165, Evalue=2e-41, Organism=Caenorhabditis elegans, GI17566692, Length=300, Percent_Identity=30.6666666666667, Blast_Score=153, Evalue=8e-38, Organism=Caenorhabditis elegans, GI17537079, Length=300, Percent_Identity=30.6666666666667, Blast_Score=153, Evalue=1e-37, Organism=Caenorhabditis elegans, GI17561300, Length=275, Percent_Identity=30.1818181818182, Blast_Score=144, Evalue=6e-35, Organism=Caenorhabditis elegans, GI17538386, Length=275, Percent_Identity=29.8181818181818, Blast_Score=139, Evalue=2e-33, Organism=Caenorhabditis elegans, GI17552492, Length=274, Percent_Identity=26.6423357664234, Blast_Score=138, Evalue=3e-33, Organism=Caenorhabditis elegans, GI17562292, Length=276, Percent_Identity=27.536231884058, Blast_Score=133, Evalue=1e-31, Organism=Saccharomyces cerevisiae, GI6320576, Length=288, Percent_Identity=37.1527777777778, Blast_Score=188, Evalue=7e-49, Organism=Saccharomyces cerevisiae, GI6324694, Length=285, Percent_Identity=35.4385964912281, Blast_Score=182, Evalue=4e-47, Organism=Saccharomyces cerevisiae, GI6321896, Length=304, Percent_Identity=34.8684210526316, Blast_Score=172, Evalue=4e-44, Organism=Saccharomyces cerevisiae, GI6322556, Length=280, Percent_Identity=31.4285714285714, Blast_Score=145, Evalue=9e-36, Organism=Saccharomyces cerevisiae, GI6319625, Length=279, Percent_Identity=29.7491039426523, Blast_Score=128, Evalue=1e-30, Organism=Saccharomyces cerevisiae, GI6320079, Length=230, Percent_Identity=31.304347826087, Blast_Score=126, Evalue=4e-30, Organism=Drosophila melanogaster, GI24663317, Length=294, Percent_Identity=37.0748299319728, Blast_Score=189, Evalue=2e-48, Organism=Drosophila melanogaster, GI45553081, Length=293, Percent_Identity=34.1296928327645, Blast_Score=184, Evalue=6e-47, Organism=Drosophila melanogaster, GI24644950, Length=298, Percent_Identity=36.9127516778523, Blast_Score=184, Evalue=8e-47, Organism=Drosophila melanogaster, GI24657054, Length=284, Percent_Identity=36.2676056338028, Blast_Score=183, Evalue=1e-46, Organism=Drosophila melanogaster, GI20129731, Length=292, Percent_Identity=37.3287671232877, Blast_Score=178, Evalue=4e-45, Organism=Drosophila melanogaster, GI221378297, Length=318, Percent_Identity=34.5911949685535, Blast_Score=176, Evalue=2e-44, Organism=Drosophila melanogaster, GI21356425, Length=291, Percent_Identity=33.6769759450172, Blast_Score=174, Evalue=8e-44, Organism=Drosophila melanogaster, GI24662789, Length=295, Percent_Identity=33.5593220338983, Blast_Score=164, Evalue=7e-41, Organism=Drosophila melanogaster, GI24662781, Length=281, Percent_Identity=36.6548042704626, Blast_Score=147, Evalue=7e-36, Organism=Drosophila melanogaster, GI281366140, Length=252, Percent_Identity=32.5396825396825, Blast_Score=147, Evalue=7e-36, Organism=Drosophila melanogaster, GI24662785, Length=280, Percent_Identity=36.4285714285714, Blast_Score=144, Evalue=9e-35,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR018170 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: =1.1.1.283 [H]
Molecular weight: Translated: 31848; Mature: 31716
Theoretical pI: Translated: 5.15; Mature: 5.15
Prosite motif: PS00798 ALDOKETO_REDUCTASE_1 ; PS00062 ALDOKETO_REDUCTASE_2 ; PS00063 ALDOKETO_REDUCTASE_3
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTIIPTVSLNAGIAMPILGFGVFQITDAAECERAVSDAIQTGYRLIDTAAVYGNEAAVGA CEEECEECCCCCCHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH AIARSGVAREDLFVTTKLWIQDTGYEQTKAAFERSLQRLGLDYLDLYLIHQPYGDIYGAW HHHHCCCCHHHEEEEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHEECCCHHHHHHH RAMEELYQAGRIRAIGVSNFHPDRVMDLIVHNQVPPAVNQIETHPFQQQIDTQQFLQQQG HHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHCC VQIESWGPFAEGKHAIFQNELLAGIAATHQKTVAQVILRWLTQRGVVAIPKSVRKERMEE CEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHC NFNVFDITLSPEEMAAISTLDTKTSSFFDHRDPAVVKMLGEANRPT CCCEEEEEECHHHHHHHHHHCCCHHHHHCCCCHHHHHHHCCCCCCC >Mature Secondary Structure TIIPTVSLNAGIAMPILGFGVFQITDAAECERAVSDAIQTGYRLIDTAAVYGNEAAVGA EEECEECCCCCCHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH AIARSGVAREDLFVTTKLWIQDTGYEQTKAAFERSLQRLGLDYLDLYLIHQPYGDIYGAW HHHHCCCCHHHEEEEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHEECCCHHHHHHH RAMEELYQAGRIRAIGVSNFHPDRVMDLIVHNQVPPAVNQIETHPFQQQIDTQQFLQQQG HHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHCC VQIESWGPFAEGKHAIFQNELLAGIAATHQKTVAQVILRWLTQRGVVAIPKSVRKERMEE CEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHC NFNVFDITLSPEEMAAISTLDTKTSSFFDHRDPAVVKMLGEANRPT CCCEEEEEECHHHHHHHHHHCCCHHHHHCCCCHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9639930; 9384377 [H]