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The map label for this gene is scn [H]

Identifier: 15927516

GI number: 15927516

Start: 2006528

End: 2006878

Strand: Reverse

Name: scn [H]

Synonym: SA1754

Alternate gene names: 15927516

Gene position: 2006878-2006528 (Counterclockwise)

Preceding gene: 15927518

Following gene: 15927512

Centisome position: 71.3

GC content: 29.06

Gene sequence:

>351_bases
ATGAAAATTAGAAAATCTATACTTGCGGGAACTTTAGCAATCGTTTTAGCATCACCACTAGTAACTAATCTAGATAAAAA
TGAGGCACAAGCTAGCACAAGCTTGCCAACATCGAATGAATATCAAAACGAAAAGTTAGCTAATGAATTAAAATCGTTAT
TAGATGAACTAAATGTTAATGAATTAGCTACTGGAAGTTTAAACACTTATTATAAGCGAACTATAAAAATTTCAGGTCTA
AAAGCAATGTATGCTCTTAAGTCAAAAGACTTTAAGAAAATGTCAGAAGCAAAATATCAACTTCAAAAGATTTATAACGA
AATTGACGAAGCACTAAAAAGTAAATATTAA

Upstream 100 bases:

>100_bases
CATTTAATAAGAAGATCTATATAGTTAATGAATAATTAATGTACTTTTTTTTAGTTAGTCATTAAAATAAATTAGTACTA
ATTACTAAGGAGAATAAAAA

Downstream 100 bases:

>100_bases
AAAAACCACCCTTTTACGGGTGGTTTTAATTTTCTAGATAATATAAAAGTGTTCATAAATAAAACAGTATAGGCAAACAA
TAAAGTATTGAAAAAAGTAA

Product: hypothetical protein

Products: NA

Alternate protein names: SCIN [H]

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MKIRKSILAGTLAIVLASPLVTNLDKNEAQASTSLPTSNEYQNEKLANELKSLLDELNVNELATGSLNTYYKRTIKISGL
KAMYALKSKDFKKMSEAKYQLQKIYNEIDEALKSKY

Sequences:

>Translated_116_residues
MKIRKSILAGTLAIVLASPLVTNLDKNEAQASTSLPTSNEYQNEKLANELKSLLDELNVNELATGSLNTYYKRTIKISGL
KAMYALKSKDFKKMSEAKYQLQKIYNEIDEALKSKY
>Mature_116_residues
MKIRKSILAGTLAIVLASPLVTNLDKNEAQASTSLPTSNEYQNEKLANELKSLLDELNVNELATGSLNTYYKRTIKISGL
KAMYALKSKDFKKMSEAKYQLQKIYNEIDEALKSKY

Specific function: Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inacti

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SCIN family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021612 [H]

Pfam domain/function: PF11546 CompInhib_SCIN [H]

EC number: NA

Molecular weight: Translated: 13052; Mature: 13052

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRKSILAGTLAIVLASPLVTNLDKNEAQASTSLPTSNEYQNEKLANELKSLLDELNVN
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHH
ELATGSLNTYYKRTIKISGLKAMYALKSKDFKKMSEAKYQLQKIYNEIDEALKSKY
HHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIRKSILAGTLAIVLASPLVTNLDKNEAQASTSLPTSNEYQNEKLANELKSLLDELNVN
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHH
ELATGSLNTYYKRTIKISGLKAMYALKSKDFKKMSEAKYQLQKIYNEIDEALKSKY
HHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA