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The map label for this gene is 15927381

Identifier: 15927381

GI number: 15927381

Start: 1857930

End: 1859159

Strand: Reverse

Name: 15927381

Synonym: SA1625

Alternate gene names: NA

Gene position: 1859159-1857930 (Counterclockwise)

Preceding gene: 15927382

Following gene: 15927380

Centisome position: 66.05

GC content: 28.78

Gene sequence:

>1230_bases
ATGAGTAATACACAAACGAAAAATGTGCCAGAGTTGAGATTCCCAGGATTTGAGGGCGAATGGGAAGAGAAGAAGTTAGG
GAATCTTACTACCAAAATAGGTAGTGGAAAGACTCCCAAAGGTGGAAGTGAAAACTATACAAACAAAGGCATACCATTTT
TAAGGAGTCAAAATATTAGAAATGGTAAATTAAATCTTAATGACTTAGTTTATATTAGTAAAGATATAGATGATGAGATG
AAAAATAGTAGAACGTACTATGGTGATGTTCTTTTAAATATTACAGGAGCATCAATAGGTAGAACAGCCATTAATTCGAT
AGTTGAAACGCATGCTAATTTAAATCAACATGTATGTATTATTAGATTAAAAAAAGAGTATTATTATAATTTTTTTGGAC
AGTATCTATTATCAAGAAAAGGTAAAAGAAAAATTTTCCTTGCACAAAGTGGAGGTAGTCGAGAAGGACTAAACTTCAAA
GAAATTGCTAATTTAAAAATCTTCACCCCAACTATATTTGAAGAACAACAAAAAATAGGACAATTCTTCAGCAAACTTGA
CCAACAAATTGAATTAGAAGAACAAAAACTTGAATTACTTCAACAACAGAAAAAATGCTATATACAGAAAATCTTCTCAC
AAGAATTACGATTCAAAGATGAAGAAGGTAATTACTATAAAGGATGGAACAAAAAGCAATTAAAAGATGTATTAGAATTT
AGTAATAAAAGAACTATTAATGAAAATGAATATCCTGTTTTAACATCGTCAAGACAAGGTTTAATACTTCAGTCAGACTA
CTATAAAGATAGGAAAACTTTTGCAGAGAGTAATATTGGGTATTTCATACTCCCTAAAAATCATATAACATACCGTTCAA
GAAGCGACGATGGAATTTTTAAGTTTAATTTAAATCTAATGATTGATGTAGGTATTATTAGTAAATATTACCCTGTCTTT
AAAGGGATAGATGCAAATCAATATTATTTAACATTACACTTAAACTATCAACTGAAAAAAGAATATATTAAATATGCAAC
TGGTACATCACAATTGGTACTCTCACAAAAAGACTTGCAAAACATAAAGACTAAATTGCCATCTTATGAAGAACAACAAA
AAATCGGTGATTTTTTCAGTGAAATAGATAGATTGGTTGAAAAACAATCTTCAAAAGTCGGACGATTAAAAGTACGTAAA
AAAGAACTATTACAAAAAATGTTTGTTTAA

Upstream 100 bases:

>100_bases
TTAGATCAAGTCCAACAAGATTTGAAAAATATCGACAAAGAAATCGCAGAAATTGAACAAGAAATCAATGCATACCTGAA
AGAACTTGGGGTGTTGAAAG

Downstream 100 bases:

>100_bases
TCCAGATAACAGCCTATTAATTAAAATGATAAAAATTCTATGAATAAATTGTAATATATTAATATTGAAACTATTATAAT
TTGGGATTTATTTTTTTGGA

Product: specificity determinant HsdS

Products: NA

Alternate protein names: S.MjaXIP; Type I restriction enzyme MjaXIP specificity protein; S protein [H]

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MSNTQTKNVPELRFPGFEGEWEEKKLGNLTTKIGSGKTPKGGSENYTNKGIPFLRSQNIRNGKLNLNDLVYISKDIDDEM
KNSRTYYGDVLLNITGASIGRTAINSIVETHANLNQHVCIIRLKKEYYYNFFGQYLLSRKGKRKIFLAQSGGSREGLNFK
EIANLKIFTPTIFEEQQKIGQFFSKLDQQIELEEQKLELLQQQKKCYIQKIFSQELRFKDEEGNYYKGWNKKQLKDVLEF
SNKRTINENEYPVLTSSRQGLILQSDYYKDRKTFAESNIGYFILPKNHITYRSRSDDGIFKFNLNLMIDVGIISKYYPVF
KGIDANQYYLTLHLNYQLKKEYIKYATGTSQLVLSQKDLQNIKTKLPSYEEQQKIGDFFSEIDRLVEKQSSKVGRLKVRK
KELLQKMFV

Sequences:

>Translated_409_residues
MSNTQTKNVPELRFPGFEGEWEEKKLGNLTTKIGSGKTPKGGSENYTNKGIPFLRSQNIRNGKLNLNDLVYISKDIDDEM
KNSRTYYGDVLLNITGASIGRTAINSIVETHANLNQHVCIIRLKKEYYYNFFGQYLLSRKGKRKIFLAQSGGSREGLNFK
EIANLKIFTPTIFEEQQKIGQFFSKLDQQIELEEQKLELLQQQKKCYIQKIFSQELRFKDEEGNYYKGWNKKQLKDVLEF
SNKRTINENEYPVLTSSRQGLILQSDYYKDRKTFAESNIGYFILPKNHITYRSRSDDGIFKFNLNLMIDVGIISKYYPVF
KGIDANQYYLTLHLNYQLKKEYIKYATGTSQLVLSQKDLQNIKTKLPSYEEQQKIGDFFSEIDRLVEKQSSKVGRLKVRK
KELLQKMFV
>Mature_408_residues
SNTQTKNVPELRFPGFEGEWEEKKLGNLTTKIGSGKTPKGGSENYTNKGIPFLRSQNIRNGKLNLNDLVYISKDIDDEMK
NSRTYYGDVLLNITGASIGRTAINSIVETHANLNQHVCIIRLKKEYYYNFFGQYLLSRKGKRKIFLAQSGGSREGLNFKE
IANLKIFTPTIFEEQQKIGQFFSKLDQQIELEEQKLELLQQQKKCYIQKIFSQELRFKDEEGNYYKGWNKKQLKDVLEFS
NKRTINENEYPVLTSSRQGLILQSDYYKDRKTFAESNIGYFILPKNHITYRSRSDDGIFKFNLNLMIDVGIISKYYPVFK
GIDANQYYLTLHLNYQLKKEYIKYATGTSQLVLSQKDLQNIKTKLPSYEEQQKIGDFFSEIDRLVEKQSSKVGRLKVRKK
ELLQKMFV

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 47803; Mature: 47672

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTQTKNVPELRFPGFEGEWEEKKLGNLTTKIGSGKTPKGGSENYTNKGIPFLRSQNIR
CCCCCCCCCCCCCCCCCCCCCHHHHHCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
NGKLNLNDLVYISKDIDDEMKNSRTYYGDVLLNITGASIGRTAINSIVETHANLNQHVCI
CCCCCCCEEEEEECCCCHHHHCCCEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEE
IRLKKEYYYNFFGQYLLSRKGKRKIFLAQSGGSREGLNFKEIANLKIFTPTIFEEQQKIG
EEEEHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHCCEEEECCHHHHHHHHHH
QFFSKLDQQIELEEQKLELLQQQKKCYIQKIFSQELRFKDEEGNYYKGWNKKQLKDVLEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCEECCCCHHHHHHHHHH
SNKRTINENEYPVLTSSRQGLILQSDYYKDRKTFAESNIGYFILPKNHITYRSRSDDGIF
CCCCCCCCCCCCEEECCCCCEEEECCCCHHHHHHHHCCCCEEEEECCCEEEECCCCCCEE
KFNLNLMIDVGIISKYYPVFKGIDANQYYLTLHLNYQLKKEYIKYATGTSQLVLSQKDLQ
EEEEEEEEEECHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHHHHCCCCHHEEECHHHHH
NIKTKLPSYEEQQKIGDFFSEIDRLVEKQSSKVGRLKVRKKELLQKMFV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNTQTKNVPELRFPGFEGEWEEKKLGNLTTKIGSGKTPKGGSENYTNKGIPFLRSQNIR
CCCCCCCCCCCCCCCCCCCCHHHHHCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
NGKLNLNDLVYISKDIDDEMKNSRTYYGDVLLNITGASIGRTAINSIVETHANLNQHVCI
CCCCCCCEEEEEECCCCHHHHCCCEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEE
IRLKKEYYYNFFGQYLLSRKGKRKIFLAQSGGSREGLNFKEIANLKIFTPTIFEEQQKIG
EEEEHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHCCEEEECCHHHHHHHHHH
QFFSKLDQQIELEEQKLELLQQQKKCYIQKIFSQELRFKDEEGNYYKGWNKKQLKDVLEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCEECCCCHHHHHHHHHH
SNKRTINENEYPVLTSSRQGLILQSDYYKDRKTFAESNIGYFILPKNHITYRSRSDDGIF
CCCCCCCCCCCCEEECCCCCEEEECCCCHHHHHHHHCCCCEEEEECCCEEEECCCCCCEE
KFNLNLMIDVGIISKYYPVFKGIDANQYYLTLHLNYQLKKEYIKYATGTSQLVLSQKDLQ
EEEEEEEEEECHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHHHHCCCCHHEEECHHHHH
NIKTKLPSYEEQQKIGDFFSEIDRLVEKQSSKVGRLKVRKKELLQKMFV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]