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The map label for this gene is menC

Identifier: 15927370

GI number: 15927370

Start: 1848297

End: 1849298

Strand: Reverse

Name: menC

Synonym: SA1614

Alternate gene names: 15927370

Gene position: 1849298-1848297 (Counterclockwise)

Preceding gene: 15927371

Following gene: 15927368

Centisome position: 65.7

GC content: 36.33

Gene sequence:

>1002_bases
ATGAAGTTGACAGCTTTGCATTTTTATAAATATAGTGAGCCATTTAAGTCACAAATTGTAACACCGAAAGTCACTTTAAC
GCATCGTGATTGTTTGTTTATCGAATTGATTGATGACAAAGGAAATGCATATTTCGGGGAATGTAACGCTTTTCAAACAG
ATTGGTATGATCATGAAACAATTGCTTCAGTGAAACATGTAATTGAGCAATGGTTCGAAGATAATAGAAATAAATCATTT
GAAACGTATGAAGCAGCACTAAAATTAGTAGATTCATTGGAAAATACGCCTGCTGCAAGGGCAACTATTGTCATGGCATT
GTATCAAATGTTTCATGTACTGCCTTCATTTTCAGTAGCATATGGAGCGACAGCGAGCGGCTTATCAAATAAACAACTAG
AGTCATTGAAAGCAACAAAGCCGACCAGAATTAAATTAAAATGGACGCCTCAAATCATGCATCAAATTAGAGTGTTACGG
GAATTAGACTTTCACTTTCAATTGGTTATAGATGCAAATGAGTCATTGGATCGTCAAGATTTCACACAGTTACAGCTATT
AGCGCGTGAACAGGTTCTTTATATCGAAGAGCCATTTAAAGATATCTCCATGCTTGATGAAGTAGTGGATGGAACAATAC
CTCCAATAGCCCTTGATGAAAAGGCAACATCGTTGTTGGACATAATTAATTTGATAGAATTATACAATGTGAAAGTTGTT
GTATTAAAACCATTTCGTCTAGGTGGCATTGATAAAGTGCAAACGGCAATTGATACTTTGAAAAGTCATGGTGTAAAAGT
GGTTATTGGCGGCATGTACGAATATGGTTTAAGCCGTTATTTTACAGCGATGCTTGCTCGTAAAGGTGATTATCCAGGAG
ATGTTACACCAGCAGGTTATTATTTTGATCAAGATGTGGTTACTAAATCAGGCATATTAAAAGAGGGGCGACTCGAATTT
CGCCCCCCTTTAGTGGATATAACTCAATTACAACCATATTAA

Upstream 100 bases:

>100_bases
GCGAAATATAAAGTACCGAAACACTTTGAAAAGGTTGATACTTTACCTTATACATCAACGGGTAAATTACAGAGAAATAA
GTTGTATAGAGGATGATTTG

Downstream 100 bases:

>100_bases
TGGTTATGTTTATGTGAATGCTTGCTTGCTGACTTGTCTTTTTTTAACGGAACAGGGTCAAAGCCACCTTTATGAAGCGG
ATGACATTTTAAAATACGAC

Product: o-succinylbenzoic acid synthetase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKLTALHFYKYSEPFKSQIVTPKVTLTHRDCLFIELIDDKGNAYFGECNAFQTDWYDHETIASVKHVIEQWFEDNRNKSF
ETYEAALKLVDSLENTPAARATIVMALYQMFHVLPSFSVAYGATASGLSNKQLESLKATKPTRIKLKWTPQIMHQIRVLR
ELDFHFQLVIDANESLDRQDFTQLQLLAREQVLYIEEPFKDISMLDEVVDGTIPPIALDEKATSLLDIINLIELYNVKVV
VLKPFRLGGIDKVQTAIDTLKSHGVKVVIGGMYEYGLSRYFTAMLARKGDYPGDVTPAGYYFDQDVVTKSGILKEGRLEF
RPPLVDITQLQPY

Sequences:

>Translated_333_residues
MKLTALHFYKYSEPFKSQIVTPKVTLTHRDCLFIELIDDKGNAYFGECNAFQTDWYDHETIASVKHVIEQWFEDNRNKSF
ETYEAALKLVDSLENTPAARATIVMALYQMFHVLPSFSVAYGATASGLSNKQLESLKATKPTRIKLKWTPQIMHQIRVLR
ELDFHFQLVIDANESLDRQDFTQLQLLAREQVLYIEEPFKDISMLDEVVDGTIPPIALDEKATSLLDIINLIELYNVKVV
VLKPFRLGGIDKVQTAIDTLKSHGVKVVIGGMYEYGLSRYFTAMLARKGDYPGDVTPAGYYFDQDVVTKSGILKEGRLEF
RPPLVDITQLQPY
>Mature_333_residues
MKLTALHFYKYSEPFKSQIVTPKVTLTHRDCLFIELIDDKGNAYFGECNAFQTDWYDHETIASVKHVIEQWFEDNRNKSF
ETYEAALKLVDSLENTPAARATIVMALYQMFHVLPSFSVAYGATASGLSNKQLESLKATKPTRIKLKWTPQIMHQIRVLR
ELDFHFQLVIDANESLDRQDFTQLQLLAREQVLYIEEPFKDISMLDEVVDGTIPPIALDEKATSLLDIINLIELYNVKVV
VLKPFRLGGIDKVQTAIDTLKSHGVKVVIGGMYEYGLSRYFTAMLARKGDYPGDVTPAGYYFDQDVVTKSGILKEGRLEF
RPPLVDITQLQPY

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354
- InterPro:   IPR010197 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 38031; Mature: 38031

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTALHFYKYSEPFKSQIVTPKVTLTHRDCLFIELIDDKGNAYFGECNAFQTDWYDHET
CCEEEEEHHHCCCCHHHCCCCCEEEEEECCEEEEEEEECCCCEEEECCCCCCCCCCCHHH
IASVKHVIEQWFEDNRNKSFETYEAALKLVDSLENTPAARATIVMALYQMFHVLPSFSVA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHH
YGATASGLSNKQLESLKATKPTRIKLKWTPQIMHQIRVLRELDFHFQLVIDANESLDRQD
CCCCCCCCCHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCCEEEEEEECCCCCCHHH
FTQLQLLAREQVLYIEEPFKDISMLDEVVDGTIPPIALDEKATSLLDIINLIELYNVKVV
HHHHHHHHHHHEEEECCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHCEEEE
VLKPFRLGGIDKVQTAIDTLKSHGVKVVIGGMYEYGLSRYFTAMLARKGDYPGDVTPAGY
EECCCCCCCHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
YFDQDVVTKSGILKEGRLEFRPPLVDITQLQPY
EECHHHHHHCCCCCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure
MKLTALHFYKYSEPFKSQIVTPKVTLTHRDCLFIELIDDKGNAYFGECNAFQTDWYDHET
CCEEEEEHHHCCCCHHHCCCCCEEEEEECCEEEEEEEECCCCEEEECCCCCCCCCCCHHH
IASVKHVIEQWFEDNRNKSFETYEAALKLVDSLENTPAARATIVMALYQMFHVLPSFSVA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHH
YGATASGLSNKQLESLKATKPTRIKLKWTPQIMHQIRVLRELDFHFQLVIDANESLDRQD
CCCCCCCCCHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCCEEEEEEECCCCCCHHH
FTQLQLLAREQVLYIEEPFKDISMLDEVVDGTIPPIALDEKATSLLDIINLIELYNVKVV
HHHHHHHHHHHEEEECCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHCEEEE
VLKPFRLGGIDKVQTAIDTLKSHGVKVVIGGMYEYGLSRYFTAMLARKGDYPGDVTPAGY
EECCCCCCCHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
YFDQDVVTKSGILKEGRLEFRPPLVDITQLQPY
EECHHHHHHCCCCCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10194342 [H]