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The map label for this gene is aroC

Identifier: 15927047

GI number: 15927047

Start: 1505516

End: 1506682

Strand: Reverse

Name: aroC

Synonym: SA1299

Alternate gene names: 15927047

Gene position: 1506682-1505516 (Counterclockwise)

Preceding gene: 15927048

Following gene: 15927046

Centisome position: 53.53

GC content: 35.3

Gene sequence:

>1167_bases
ATGAGATATCTAACTTCAGGAGAATCACATGGACCTCAATTAACAGTTATTGTCGAAGGTATACCAGCAAATTTAGAAAT
TAAAGTTGAAGATATTAATAAAGAAATGTTCAAGCGTCAAGGGGGTTATGGTCGTGGCCGACGCATGCAAATTGAGAAAG
ATACAGTAGAAATAGTATCAGGCGTTAGAAATGGTTATACATTAGGTAGTCCAATTACTATGGTTGTAACCAATGATGAC
TTTACGCATTGGAGAAAAATTATGGGAGCAGCTCCAATAAGTGAAGAAGAACGTGAAAATATGAAACGTACTATTACAAA
ACCAAGACCTGGTCATGCAGATTTGGTTGGAGGTATGAAATATAATCATCGTGATTTACGAAATGTGCTAGAGCGATCAT
CTGCTAGAGAAACAGCAGCTCGAGTTGCAGTCGGTGCCTTATGTAAAGTGTTATTACAACAGTTAGATATCGATATATAC
AGTCGTGTTGTTGAAATAGGTGGCATTAAAGATAAAGATTTTTATGATTCAGAAACATTTAAAGCAAATCTTGATCGTAA
TGATGTTCGTGTAATTGATGACAGTATCGCACAAGCAATGCGAGATAAAATTGACGAAGCTAAAAATGAAGGAGATTCAA
TTGGCGGTGTCGTTCAAGTTGTAGTTGAAAATATGCCTGTTGGTGTTGGTAGTTATGTGCATTATGATCGTAAGTTAGAT
GGTAAGATTGCACAAGGTGTTGTCAGCATAAATGCTTTTAAAGGTGTAAGCTTTGGAGAAGGATTTAAAGCAGCTGAAAA
GCCAGGTAGTGAGATTCAAGATGAAATTCTATATAATAGTGAAATTGGTTATTATCGTGGATCTAATCATTTAGGTGGTT
TAGAGGGTGGTATGTCAAATGGTATGCCAATTATTGTAAATGGTGTAATGAAACCTATTCCTACGTTATATAAACCATTA
AATTCAGTTGATATAAATACTAAAGAAGACTTTAAGGCAACAATTGAACGTTCTGATAGTTGTGCTGTACCTGCAGCAAG
TATAGTGTGTGAACACGTTGTTGCATTTGAAATAGCGAAAGCATTACTTGAAGAGTTTCAATCAAACCATATTGAACAAC
TTCAACAACAAATTGCTGACCGCAGACAATTAAATGTTGAGTTTTAA

Upstream 100 bases:

>100_bases
ATTAAGCTTGAAAACAAACATTTATGAATCCACAATGAATGTGATAAGATTAACAACATATTATAATGTTATTGCGGAAG
TATGAAAGGAGCGAGTGTGT

Downstream 100 bases:

>100_bases
CAACGAGAACAATTGAGGTGTGATCATGAAATTACAAACAACCTATCCTTCAAACAATTATCCAATATTTGTTGAACATG
GTGCAATTGACCATATTAGC

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MRYLTSGESHGPQLTVIVEGIPANLEIKVEDINKEMFKRQGGYGRGRRMQIEKDTVEIVSGVRNGYTLGSPITMVVTNDD
FTHWRKIMGAAPISEEERENMKRTITKPRPGHADLVGGMKYNHRDLRNVLERSSARETAARVAVGALCKVLLQQLDIDIY
SRVVEIGGIKDKDFYDSETFKANLDRNDVRVIDDSIAQAMRDKIDEAKNEGDSIGGVVQVVVENMPVGVGSYVHYDRKLD
GKIAQGVVSINAFKGVSFGEGFKAAEKPGSEIQDEILYNSEIGYYRGSNHLGGLEGGMSNGMPIIVNGVMKPIPTLYKPL
NSVDINTKEDFKATIERSDSCAVPAASIVCEHVVAFEIAKALLEEFQSNHIEQLQQQIADRRQLNVEF

Sequences:

>Translated_388_residues
MRYLTSGESHGPQLTVIVEGIPANLEIKVEDINKEMFKRQGGYGRGRRMQIEKDTVEIVSGVRNGYTLGSPITMVVTNDD
FTHWRKIMGAAPISEEERENMKRTITKPRPGHADLVGGMKYNHRDLRNVLERSSARETAARVAVGALCKVLLQQLDIDIY
SRVVEIGGIKDKDFYDSETFKANLDRNDVRVIDDSIAQAMRDKIDEAKNEGDSIGGVVQVVVENMPVGVGSYVHYDRKLD
GKIAQGVVSINAFKGVSFGEGFKAAEKPGSEIQDEILYNSEIGYYRGSNHLGGLEGGMSNGMPIIVNGVMKPIPTLYKPL
NSVDINTKEDFKATIERSDSCAVPAASIVCEHVVAFEIAKALLEEFQSNHIEQLQQQIADRRQLNVEF
>Mature_388_residues
MRYLTSGESHGPQLTVIVEGIPANLEIKVEDINKEMFKRQGGYGRGRRMQIEKDTVEIVSGVRNGYTLGSPITMVVTNDD
FTHWRKIMGAAPISEEERENMKRTITKPRPGHADLVGGMKYNHRDLRNVLERSSARETAARVAVGALCKVLLQQLDIDIY
SRVVEIGGIKDKDFYDSETFKANLDRNDVRVIDDSIAQAMRDKIDEAKNEGDSIGGVVQVVVENMPVGVGSYVHYDRKLD
GKIAQGVVSINAFKGVSFGEGFKAAEKPGSEIQDEILYNSEIGYYRGSNHLGGLEGGMSNGMPIIVNGVMKPIPTLYKPL
NSVDINTKEDFKATIERSDSCAVPAASIVCEHVVAFEIAKALLEEFQSNHIEQLQQQIADRRQLNVEF

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=370, Percent_Identity=33.7837837837838, Blast_Score=144, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6321290, Length=376, Percent_Identity=33.5106382978723, Blast_Score=171, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_STAA1 (A7X2G8)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442044.1
- ProteinModelPortal:   A7X2G8
- SMR:   A7X2G8
- STRING:   A7X2G8
- EnsemblBacteria:   EBSTAT00000003043
- GeneID:   5559583
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1454
- eggNOG:   COG0082
- GeneTree:   EBGT00050000024286
- HOGENOM:   HBG292336
- OMA:   GSEAHDE
- ProtClustDB:   PRK05382
- BioCyc:   SAUR418127:SAHV_1454-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 42991; Mature: 42991

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYLTSGESHGPQLTVIVEGIPANLEIKVEDINKEMFKRQGGYGRGRRMQIEKDTVEIVS
CCCCCCCCCCCCEEEEEEECCCCCEEEEEEHHHHHHHHHCCCCCCCCEEEEHHHHHHHHH
GVRNGYTLGSPITMVVTNDDFTHWRKIMGAAPISEEERENMKRTITKPRPGHADLVGGMK
HHHCCEECCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHCCCCC
YNHRDLRNVLERSSARETAARVAVGALCKVLLQQLDIDIYSRVVEIGGIKDKDFYDSETF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCE
KANLDRNDVRVIDDSIAQAMRDKIDEAKNEGDSIGGVVQVVVENMPVGVGSYVHYDRKLD
EECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHEECCCCCC
GKIAQGVVSINAFKGVSFGEGFKAAEKPGSEIQDEILYNSEIGYYRGSNHLGGLEGGMSN
CHHHHHHHEEEHCCCCCCCCCCCHHCCCCCHHHHHHHCCCCCCEEECCCCCCCCCCCCCC
GMPIIVNGVMKPIPTLYKPLNSVDINTKEDFKATIERSDSCAVPAASIVCEHVVAFEIAK
CCCEEECCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
ALLEEFQSNHIEQLQQQIADRRQLNVEF
HHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRYLTSGESHGPQLTVIVEGIPANLEIKVEDINKEMFKRQGGYGRGRRMQIEKDTVEIVS
CCCCCCCCCCCCEEEEEEECCCCCEEEEEEHHHHHHHHHCCCCCCCCEEEEHHHHHHHHH
GVRNGYTLGSPITMVVTNDDFTHWRKIMGAAPISEEERENMKRTITKPRPGHADLVGGMK
HHHCCEECCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHCCCCC
YNHRDLRNVLERSSARETAARVAVGALCKVLLQQLDIDIYSRVVEIGGIKDKDFYDSETF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCE
KANLDRNDVRVIDDSIAQAMRDKIDEAKNEGDSIGGVVQVVVENMPVGVGSYVHYDRKLD
EECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHEECCCCCC
GKIAQGVVSINAFKGVSFGEGFKAAEKPGSEIQDEILYNSEIGYYRGSNHLGGLEGGMSN
CHHHHHHHEEEHCCCCCCCCCCCHHCCCCCHHHHHHHCCCCCCEEECCCCCCCCCCCCCC
GMPIIVNGVMKPIPTLYKPLNSVDINTKEDFKATIERSDSCAVPAASIVCEHVVAFEIAK
CCCEEECCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
ALLEEFQSNHIEQLQQQIADRRQLNVEF
HHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA