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The map label for this gene is aroA

Identifier: 15927045

GI number: 15927045

Start: 1503118

End: 1504416

Strand: Reverse

Name: aroA

Synonym: SA1297

Alternate gene names: 15927045

Gene position: 1504416-1503118 (Counterclockwise)

Preceding gene: 15927046

Following gene: 15927044

Centisome position: 53.45

GC content: 34.41

Gene sequence:

>1299_bases
ATGGTAAGTGAACAAATTATCGATATTTCAGGGCCACTTAAAGGTGAAATAGAAGTGCCTGGAGATAAGTCGATGACACA
TCGAGCAATCATGTTAGCATCTTTAGCTGAAGGAACTTCCAATATTTATAAACCATTACTTGGTGAAGATTGTCGTCGTA
CAATGGATATATTCCGATTATTAGGCGTAGATATTAAAGAAGATGAAGATAAATTGGTTGTGAATTCACCTGGATATAAA
GCTTTTAAAACACCTCATCAAGTTTTATATACTGGAAACTCTGGCACAACGACTCGATTGTTAGCTGGTTTGTTAAGTGG
TTTAGGTATTGAAAGTGTTTTGTCTGGCGATGTTTCAATTGGTAAAAGGCCAATGGATCGTGTCTTGAGACCATTGAAAC
TTATGGATGCGAATATTGAAGGTATTGAAGATAATTATACACCATTAATTATTAAGCCATCTGTCATAAAAGGTATAAAT
TATCAAATGGAAGTTGCAAGTGCACAAGTAAAAAGTGCCATTTTATTTGCAAGTTTGTTTTCAAATGATACAACGGTAAT
AAAGGAATTAGATGTAAGTCGAAATCATACTGAGACGATGTTCAGACATTTTAATATTCCAATTGAAGCAGAAAGGTTAT
CAATAACTACAACCCCTGATGCCATTCAACATATTAAACCTGCAGATTTTCATGTTCCTGGCGATATTTCATCTGCAGCG
TTCTTTATTGTTGCAGCACTTATCACACCAGAAAGTGATGTAACAATTCATAATGTTGGAATCAATCCAACACGTTCAGG
TATTATTGATATTGTTGAAAAAATGGGCGGTAATATCCAACTTTTCAATCAAACAACTGGTGCTGAACCTACTGCTTCTA
TTCGTATTCAATACACACCAATGCTTCAACCAATAACAATCGAAGGAGAATTAGTTCCAAAAGCAATTGATGAACTGCCT
GTAATAGCATTACTTTGTACACAAGCAGTTGGCACGAGTACAATTAAAGATGCCGAGGAATTAAAAGTAAAAGAAACAAA
TAGAATTGATACAACGGCTGATATGTTAAACTTGTTAGGGTTTGAATTACAACCAACTAATGATGGATTGATTATTCATC
CGTCAGAATTTAAAACAAATGCAACAGTTGATAGTTTAACTGATCATCGAATAGGAATGATGCTTGCAGTTGCTTCTCTA
CTTTCAAGCGAGCCTGTCAAAATCAAACAATTTGATGCTGTAAATGTATCATTTCCAGGATTTTTACCAAAACTAAAGCT
TTTAGAAAATGAGGGATAA

Upstream 100 bases:

>100_bases
GATTAAACATTTTGGCGATATTGTAGTGCAACACATTGATCAAACAACACTGCAACATGCGTGTGAACAACTAAAAACAT
ATTTTAAGTAGGTGAAGTAA

Downstream 100 bases:

>100_bases
TATAAAATGGAAGATATCTATAAATTAATAGACGATATCAATCTACAAAAACTAGAAAATTTAGACTCTCGTGTTAATGA
AGCAATAACTACTGACAACG

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MVSEQIIDISGPLKGEIEVPGDKSMTHRAIMLASLAEGTSNIYKPLLGEDCRRTMDIFRLLGVDIKEDEDKLVVNSPGYK
AFKTPHQVLYTGNSGTTTRLLAGLLSGLGIESVLSGDVSIGKRPMDRVLRPLKLMDANIEGIEDNYTPLIIKPSVIKGIN
YQMEVASAQVKSAILFASLFSNDTTVIKELDVSRNHTETMFRHFNIPIEAERLSITTTPDAIQHIKPADFHVPGDISSAA
FFIVAALITPESDVTIHNVGINPTRSGIIDIVEKMGGNIQLFNQTTGAEPTASIRIQYTPMLQPITIEGELVPKAIDELP
VIALLCTQAVGTSTIKDAEELKVKETNRIDTTADMLNLLGFELQPTNDGLIIHPSEFKTNATVDSLTDHRIGMMLAVASL
LSSEPVKIKQFDAVNVSFPGFLPKLKLLENEG

Sequences:

>Translated_432_residues
MVSEQIIDISGPLKGEIEVPGDKSMTHRAIMLASLAEGTSNIYKPLLGEDCRRTMDIFRLLGVDIKEDEDKLVVNSPGYK
AFKTPHQVLYTGNSGTTTRLLAGLLSGLGIESVLSGDVSIGKRPMDRVLRPLKLMDANIEGIEDNYTPLIIKPSVIKGIN
YQMEVASAQVKSAILFASLFSNDTTVIKELDVSRNHTETMFRHFNIPIEAERLSITTTPDAIQHIKPADFHVPGDISSAA
FFIVAALITPESDVTIHNVGINPTRSGIIDIVEKMGGNIQLFNQTTGAEPTASIRIQYTPMLQPITIEGELVPKAIDELP
VIALLCTQAVGTSTIKDAEELKVKETNRIDTTADMLNLLGFELQPTNDGLIIHPSEFKTNATVDSLTDHRIGMMLAVASL
LSSEPVKIKQFDAVNVSFPGFLPKLKLLENEG
>Mature_432_residues
MVSEQIIDISGPLKGEIEVPGDKSMTHRAIMLASLAEGTSNIYKPLLGEDCRRTMDIFRLLGVDIKEDEDKLVVNSPGYK
AFKTPHQVLYTGNSGTTTRLLAGLLSGLGIESVLSGDVSIGKRPMDRVLRPLKLMDANIEGIEDNYTPLIIKPSVIKGIN
YQMEVASAQVKSAILFASLFSNDTTVIKELDVSRNHTETMFRHFNIPIEAERLSITTTPDAIQHIKPADFHVPGDISSAA
FFIVAALITPESDVTIHNVGINPTRSGIIDIVEKMGGNIQLFNQTTGAEPTASIRIQYTPMLQPITIEGELVPKAIDELP
VIALLCTQAVGTSTIKDAEELKVKETNRIDTTADMLNLLGFELQPTNDGLIIHPSEFKTNATVDSLTDHRIGMMLAVASL
LSSEPVKIKQFDAVNVSFPGFLPKLKLLENEG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=421, Percent_Identity=28.0285035629454, Blast_Score=119, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6320332, Length=456, Percent_Identity=25.6578947368421, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_STAA1 (A7X2G5)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442042.1
- ProteinModelPortal:   A7X2G5
- SMR:   A7X2G5
- STRING:   A7X2G5
- EnsemblBacteria:   EBSTAT00000002939
- GeneID:   5558937
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1452
- eggNOG:   COG0128
- GeneTree:   EBGT00050000024855
- HOGENOM:   HBG646626
- OMA:   LSRNHTE
- ProtClustDB:   PRK02427
- BioCyc:   SAUR418127:SAHV_1452-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 47069; Mature: 47069

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSEQIIDISGPLKGEIEVPGDKSMTHRAIMLASLAEGTSNIYKPLLGEDCRRTMDIFRL
CCCCEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHH
LGVDIKEDEDKLVVNSPGYKAFKTPHQVLYTGNSGTTTRLLAGLLSGLGIESVLSGDVSI
HCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCHHHHHCCCCCC
GKRPMDRVLRPLKLMDANIEGIEDNYTPLIIKPSVIKGINYQMEVASAQVKSAILFASLF
CCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHCCCCEEEEHHHHHHHHHHHHHHHH
SNDTTVIKELDVSRNHTETMFRHFNIPIEAERLSITTTPDAIQHIKPADFHVPGDISSAA
CCCCEEEEECCCCCCHHHHHHHHCCCCEEECEEEEECCHHHHHHCCCCCCCCCCCCCHHH
FFIVAALITPESDVTIHNVGINPTRSGIIDIVEKMGGNIQLFNQTTGAEPTASIRIQYTP
HHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEEEC
MLQPITIEGELVPKAIDELPVIALLCTQAVGTSTIKDAEELKVKETNRIDTTADMLNLLG
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHCCHHHHEECCCCCCCHHHHHHHHHC
FELQPTNDGLIIHPSEFKTNATVDSLTDHRIGMMLAVASLLSSEPVKIKQFDAVNVSFPG
CEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECEEEECCCC
FLPKLKLLENEG
CCCHHHHHCCCC
>Mature Secondary Structure
MVSEQIIDISGPLKGEIEVPGDKSMTHRAIMLASLAEGTSNIYKPLLGEDCRRTMDIFRL
CCCCEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHH
LGVDIKEDEDKLVVNSPGYKAFKTPHQVLYTGNSGTTTRLLAGLLSGLGIESVLSGDVSI
HCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCHHHHHCCCCCC
GKRPMDRVLRPLKLMDANIEGIEDNYTPLIIKPSVIKGINYQMEVASAQVKSAILFASLF
CCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHCCCCEEEEHHHHHHHHHHHHHHHH
SNDTTVIKELDVSRNHTETMFRHFNIPIEAERLSITTTPDAIQHIKPADFHVPGDISSAA
CCCCEEEEECCCCCCHHHHHHHHCCCCEEECEEEEECCHHHHHHCCCCCCCCCCCCCHHH
FFIVAALITPESDVTIHNVGINPTRSGIIDIVEKMGGNIQLFNQTTGAEPTASIRIQYTP
HHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEEEC
MLQPITIEGELVPKAIDELPVIALLCTQAVGTSTIKDAEELKVKETNRIDTTADMLNLLG
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHCCHHHHEECCCCCCCHHHHHHHHHC
FELQPTNDGLIIHPSEFKTNATVDSLTDHRIGMMLAVASLLSSEPVKIKQFDAVNVSFPG
CEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECEEEECCCC
FLPKLKLLENEG
CCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA