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The map label for this gene is ctpA

Identifier: 15927001

GI number: 15927001

Start: 1427597

End: 1429087

Strand: Reverse

Name: ctpA

Synonym: SA1253

Alternate gene names: 15927001

Gene position: 1429087-1427597 (Counterclockwise)

Preceding gene: 15927002

Following gene: 15927000

Centisome position: 50.77

GC content: 31.25

Gene sequence:

>1491_bases
ATGGATGATAAGCAACACACATCTTCATCCGATGATGAACGCGCTGAAATTGCAACAAGCAATCAAGACCAAGAAACTAA
TTCATCGAAACGCGTTCACTTAAAACGTTGGCAATTCATATCAATATTAATTGGCACAACCCTAATAACAGCTGTCATCA
CAGTTGTTGCATATATTTTTATAAATCAAAAAATAAGTGGTTTAAACAAAACTGATCAAGCAAACTTAAATAAAATTGAA
AATGTGTATAAAATCTTAAATAGTGATTATTACAAAAAACAGGACTCTGACAAGTTAAGTAAAGCTGCAATTGATGGTAT
GGTCAAAGAATTAAAAGATCCTTATTCTGAATATTTAACAAAAGAACAAACGAAATCCTTTAATGAAGGTGTTTCAGGTG
ATTTTGTAGGTATTGGTGCAGAAATGCAAAAGAAAAATGATCAAATTATGGTTACTAGCCCTATGAAGGGTTCTCCAGCA
GAACGTGCTGGCATCCGTCCTAAAGATGTCATTACTAAAGTAAATGGAAAATCAATTAAAGGAAAAGCATTAGACGAAGT
TGTCAAAGACGTTCGTGGTAAAGAAAACACTGAAGTAACTTTAACTGTTCAACGAGGCAGTGAAGAAAAAGACGTTAAGA
TTAAACGTGAAAAAATTCATGTTAAAAGTGTTGATTATAAGAAAAAAGGTAAGGTTGGAGTTATTACTATTAATAAATTC
CAGAATGATACATCAGGTGAATTGAAAGATGCAGTTCTTAAAGCTCACAAAGATGGTTTGAAAAAGATTGTTTTAGATTT
AAGAAATAATCCTGGTGGACTACTAGATGAAGCTGTTAAAATGGCAAATATTTTTATCGATAAAGGAAAAACTGTTGTTA
AACTAGAAAAAGGTAAAGATACTGAAGCAATTCAAACTTCTAATGACTCGTTAAAAGAAGCGAAAGACATGGATATATCC
ATCTTAGTGAATGAAGGTTCAGCTAGTGCTTCTGAAGTGTTTACTGGTGCGCTAAAGGACTATAATAAAGCTAAAGTTTA
TGGGTCAAAAACATTCGGCAAAGGTGTCGTACAAACTACAAGAGAGTTTAAGGATGGTTCATTGTTAAAATATACTGAAA
TGAAATGGTTAACGCCAGATGGTCATTATATTCACGGTAAGGGCATTAAACCAGACGTTACTATTGACACACCTAAATAT
CAATCTTTAAATGTCATTCCTAATACGAAAACATTTAAAGTTGGAGACGATGATAAAAATATTAAAACTATTAAAATTGG
TTTATCAGCTTTAGGTTATAAAGTTGATAATGAATCAACGCAATTTGATCAAGCTTTAGAAAATCAAGTTAAAGCTTTCC
AACAAGCGAATAAACTCGAGGTAACTGGTGAATTTAATAAAGAAACGAATAATAAATTTACTGAGTTATTAGTTGAAAAA
GCTAATAAACATGATGATGTTCTCGATAAGTTGATTAATATTTTAAAATAA

Upstream 100 bases:

>100_bases
AATCAATTATAGTGAAATATGGTGCGCTATCTTGCATAAATTGATATGATTAACTACACAGAATTTAAAAGTACATAATA
CATAATAAGGAAGTGATACA

Downstream 100 bases:

>100_bases
GCGATACACACTACTAAAATTGTATTATTATTATGTTAATGACACGCTTCCTAAATTTGCAAAGATAGCAATTTAGGAGG
CGTGTTTATTTTTATTGACG

Product: carboxy-terminal processing proteinase ctpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MDDKQHTSSSDDERAEIATSNQDQETNSSKRVHLKRWQFISILIGTTLITAVITVVAYIFINQKISGLNKTDQANLNKIE
NVYKILNSDYYKKQDSDKLSKAAIDGMVKELKDPYSEYLTKEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPA
ERAGIRPKDVITKVNGKSIKGKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVDYKKKGKVGVITINKF
QNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKDTEAIQTSNDSLKEAKDMDIS
ILVNEGSASASEVFTGALKDYNKAKVYGSKTFGKGVVQTTREFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKY
QSLNVIPNTKTFKVGDDDKNIKTIKIGLSALGYKVDNESTQFDQALENQVKAFQQANKLEVTGEFNKETNNKFTELLVEK
ANKHDDVLDKLINILK

Sequences:

>Translated_496_residues
MDDKQHTSSSDDERAEIATSNQDQETNSSKRVHLKRWQFISILIGTTLITAVITVVAYIFINQKISGLNKTDQANLNKIE
NVYKILNSDYYKKQDSDKLSKAAIDGMVKELKDPYSEYLTKEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPA
ERAGIRPKDVITKVNGKSIKGKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVDYKKKGKVGVITINKF
QNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKDTEAIQTSNDSLKEAKDMDIS
ILVNEGSASASEVFTGALKDYNKAKVYGSKTFGKGVVQTTREFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKY
QSLNVIPNTKTFKVGDDDKNIKTIKIGLSALGYKVDNESTQFDQALENQVKAFQQANKLEVTGEFNKETNNKFTELLVEK
ANKHDDVLDKLINILK
>Mature_496_residues
MDDKQHTSSSDDERAEIATSNQDQETNSSKRVHLKRWQFISILIGTTLITAVITVVAYIFINQKISGLNKTDQANLNKIE
NVYKILNSDYYKKQDSDKLSKAAIDGMVKELKDPYSEYLTKEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPA
ERAGIRPKDVITKVNGKSIKGKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVDYKKKGKVGVITINKF
QNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKDTEAIQTSNDSLKEAKDMDIS
ILVNEGSASASEVFTGALKDYNKAKVYGSKTFGKGVVQTTREFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKY
QSLNVIPNTKTFKVGDDDKNIKTIKIGLSALGYKVDNESTQFDQALENQVKAFQQANKLEVTGEFNKETNNKFTELLVEK
ANKHDDVLDKLINILK

Specific function: Involved In The Cleavage Of A C-Terminal Peptide Of 11 Residues From The Precursor Form Of Penicillin-Binding Protein 3 (Pbp3). May Be Involved In Protection Of The Bacterium From Thermal And Osmotic Stresses. [C]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=338, Percent_Identity=30.4733727810651, Blast_Score=135, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1 [H]

EC number: 3.4.21.102 [C]

Molecular weight: Translated: 55251; Mature: 55251

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDKQHTSSSDDERAEIATSNQDQETNSSKRVHLKRWQFISILIGTTLITAVITVVAYIF
CCCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
INQKISGLNKTDQANLNKIENVYKILNSDYYKKQDSDKLSKAAIDGMVKELKDPYSEYLT
HHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPAERAGIRPKDVITKVNGKSIK
HHHHHHHHCCCCCCEEEECCHHHCCCCEEEEECCCCCCCHHHCCCCHHHHHEECCCCCCC
GKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVDYKKKGKVGVITINKF
CHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEEEEEEEEECCCCCCCCEEEEEEECC
QNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKD
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCCEEEEEECCCC
TEAIQTSNDSLKEAKDMDISILVNEGSASASEVFTGALKDYNKAKVYGSKTFGKGVVQTT
CCCEECCCCHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCHHEEECCCCCCCHHHHHH
REFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKYQSLNVIPNTKTFKVGDDDKN
HHCCCCCEEEEECEEEECCCCCEEECCCCCCCEEECCCCCCEEEECCCCEEEEECCCCCC
IKTIKIGLSALGYKVDNESTQFDQALENQVKAFQQANKLEVTGEFNKETNNKFTELLVEK
EEEEEEEHHHHCEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHH
ANKHDDVLDKLINILK
CCCHHHHHHHHHHHHC
>Mature Secondary Structure
MDDKQHTSSSDDERAEIATSNQDQETNSSKRVHLKRWQFISILIGTTLITAVITVVAYIF
CCCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
INQKISGLNKTDQANLNKIENVYKILNSDYYKKQDSDKLSKAAIDGMVKELKDPYSEYLT
HHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPAERAGIRPKDVITKVNGKSIK
HHHHHHHHCCCCCCEEEECCHHHCCCCEEEEECCCCCCCHHHCCCCHHHHHEECCCCCCC
GKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVDYKKKGKVGVITINKF
CHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEEEEEEEEECCCCCCCCEEEEEEECC
QNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKD
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCCEEEEEECCCC
TEAIQTSNDSLKEAKDMDISILVNEGSASASEVFTGALKDYNKAKVYGSKTFGKGVVQTT
CCCEECCCCHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCHHEEECCCCCCCHHHHHH
REFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKYQSLNVIPNTKTFKVGDDDKN
HHCCCCCEEEEECEEEECCCCCEEECCCCCCCEEECCCCCCEEEECCCCEEEEECCCCCC
IKTIKIGLSALGYKVDNESTQFDQALENQVKAFQQANKLEVTGEFNKETNNKFTELLVEK
EEEEEEEHHHHCEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHH
ANKHDDVLDKLINILK
CCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Cleavage of the C-terminal peptide from the precursor form of penicillin-binding protein 3 [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA