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The map label for this gene is arlR [H]

Identifier: 15926996

GI number: 15926996

Start: 1423786

End: 1424187

Strand: Reverse

Name: arlR [H]

Synonym: SA1248

Alternate gene names: 15926996

Gene position: 1424187-1423786 (Counterclockwise)

Preceding gene: 15926997

Following gene: 15926995

Centisome position: 50.6

GC content: 34.33

Gene sequence:

>402_bases
ATGACGCAAATTTTAATAGTAGAAGATGAACAAAACTTAGCAAGATTTCTTGAATTGGAACTCACACATGAAAATTACAA
TGTGGACACAGAGTATGATGGACAAGACGGTTTAGATAAAGCGCTTAGCCATTACTATGATTTAATCATATTAGATTTAA
TGTTGCCGTCAATTAATGGCTTAGAAATTTGTCGCAAAATTAGACAACAACAATCTACACCTATCATTATAATTACAGCG
AAAAGTGATACGTATGACAAAGTTGCTGGGCTTGATTACGGTGCAGACGATTATATAGTTAAGCCGTTTGATATTGAAGA
ACTTTTAGCAAGAATTCGTGCAATTTTACGTCGTCAGCCACAAAAGGATATTATCGATGTCAACGGAACGCTTTTAAAGT
GA

Upstream 100 bases:

>100_bases
AACGTAAACAAACTAATTTAAAAAGCAACTATTGTATAGAAAAATACAAAATTTAAAATATATTACCTTATTAGAAAAAG
TCGTAATATGAGGTGTACAA

Downstream 100 bases:

>100_bases
CGGTAAATGGCGCAGAAATTGAATTAACAAAAACAGAGTATGATTTACTATATCTTCTAGCTGAAAATAAAAACCATGTT
ATGCAACGGGAACAAATTTT

Product: truncated (putative response regulator ArlR [S

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MTQILIVEDEQNLARFLELELTHENYNVDTEYDGQDGLDKALSHYYDLIILDLMLPSINGLEICRKIRQQQSTPIIIITA
KSDTYDKVAGLDYGADDYIVKPFDIEELLARIRAILRRQPQKDIIDVNGTLLK

Sequences:

>Translated_133_residues
MTQILIVEDEQNLARFLELELTHENYNVDTEYDGQDGLDKALSHYYDLIILDLMLPSINGLEICRKIRQQQSTPIIIITA
KSDTYDKVAGLDYGADDYIVKPFDIEELLARIRAILRRQPQKDIIDVNGTLLK
>Mature_132_residues
TQILIVEDEQNLARFLELELTHENYNVDTEYDGQDGLDKALSHYYDLIILDLMLPSINGLEICRKIRQQQSTPIIIITAK
SDTYDKVAGLDYGADDYIVKPFDIEELLARIRAILRRQPQKDIIDVNGTLLK

Specific function: Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=119, Percent_Identity=48.7394957983193, Blast_Score=110, Evalue=3e-26,
Organism=Escherichia coli, GI87082012, Length=117, Percent_Identity=46.1538461538462, Blast_Score=110, Evalue=4e-26,
Organism=Escherichia coli, GI1789809, Length=119, Percent_Identity=47.0588235294118, Blast_Score=109, Evalue=7e-26,
Organism=Escherichia coli, GI1786784, Length=117, Percent_Identity=46.1538461538462, Blast_Score=106, Evalue=5e-25,
Organism=Escherichia coli, GI1790552, Length=133, Percent_Identity=45.1127819548872, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI1790860, Length=116, Percent_Identity=41.3793103448276, Blast_Score=97, Evalue=4e-22,
Organism=Escherichia coli, GI1788394, Length=123, Percent_Identity=43.0894308943089, Blast_Score=96, Evalue=8e-22,
Organism=Escherichia coli, GI2367329, Length=118, Percent_Identity=44.9152542372881, Blast_Score=92, Evalue=1e-20,
Organism=Escherichia coli, GI1789402, Length=117, Percent_Identity=37.6068376068376, Blast_Score=87, Evalue=4e-19,
Organism=Escherichia coli, GI1787229, Length=116, Percent_Identity=37.9310344827586, Blast_Score=87, Evalue=5e-19,
Organism=Escherichia coli, GI1786599, Length=133, Percent_Identity=33.8345864661654, Blast_Score=86, Evalue=7e-19,
Organism=Escherichia coli, GI1787375, Length=117, Percent_Identity=38.4615384615385, Blast_Score=84, Evalue=3e-18,
Organism=Escherichia coli, GI1790863, Length=117, Percent_Identity=40.1709401709402, Blast_Score=81, Evalue=2e-17,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=30.2752293577982, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790299, Length=121, Percent_Identity=33.0578512396694, Blast_Score=67, Evalue=4e-13,
Organism=Escherichia coli, GI145693140, Length=101, Percent_Identity=32.6732673267327, Blast_Score=65, Evalue=1e-12,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=28.3333333333333, Blast_Score=62, Evalue=9e-12,
Organism=Escherichia coli, GI1788713, Length=128, Percent_Identity=31.25, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=28.9473684210526, Blast_Score=59, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 15310; Mature: 15179

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQILIVEDEQNLARFLELELTHENYNVDTEYDGQDGLDKALSHYYDLIILDLMLPSING
CCEEEEEECCHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
LEICRKIRQQQSTPIIIITAKSDTYDKVAGLDYGADDYIVKPFDIEELLARIRAILRRQP
HHHHHHHHHHCCCCEEEEEECCCCCHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHCCC
QKDIIDVNGTLLK
CCCEEECCCEEEC
>Mature Secondary Structure 
TQILIVEDEQNLARFLELELTHENYNVDTEYDGQDGLDKALSHYYDLIILDLMLPSING
CEEEEEECCHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
LEICRKIRQQQSTPIIIITAKSDTYDKVAGLDYGADDYIVKPFDIEELLARIRAILRRQP
HHHHHHHHHHCCCCEEEEEECCCCCHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHCCC
QKDIIDVNGTLLK
CCCEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA