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The map label for this gene is sbcD

Identifier: 15926926

GI number: 15926926

Start: 1341905

End: 1343026

Strand: Direct

Name: sbcD

Synonym: SA1180

Alternate gene names: 15926926

Gene position: 1341905-1343026 (Clockwise)

Preceding gene: 15926925

Following gene: 15926927

Centisome position: 47.67

GC content: 30.57

Gene sequence:

>1122_bases
ATGAAAATTATACATACAGCAGACTGGCACTTAGGGAAAATATTAAATGGCAAACAGCTTTTAGAAGATCAAGCGTATAT
TTTAGATATGTTCGTAGAAAAAATGAAAGAAGAAGAACCTGATATCATTGTGATAGCTGGAGATTTATATGACACAACAT
ATCCAAGTAAAGATGCAATCATGTTATTAGAACAAGCGATTGGAAAGTTAAATTTAGAACTGCGTATACCAATAATTATG
ATTAGTGGAAATCACGATGGTAAAGAGAGGTTAAACTATGGGGCGAGTTGGTTTGAACATAATCAGTTATTTATAAGAAC
AGATTTTACATCGATTAATTCACCAATAGAGATAAATGGGGTTAATTTTTATACACTCCCTTATGCTACTGTGAGCGAAA
TGAAACACTACTTTGAAGATGACACCATTGAAACACATCAACAGGGAATTACGCGCTGTATTGAAACAATAGCACCGGAA
ATTGATGAAGATGCCGTCAATATTTTAATTAGTCATCTGACTGTTCAAGGTGGAAAGACATCTGATTCTGAAAGACCATT
AACTATTGGAACGGTTGAATCAGTTCAGAAAGGTGTTTTTGATATATTTGATTATGTCATGCTAGGTCACTTGCATCATC
CATTTAGTATAGAAGACGACAAAATTAAATATAGTGGCTCCTTATTGCAGTATTCATTTTCGGAAGCGGGTCAAGCTAAA
GGGTATAGACGTTTAACAATTAATGATGGCATTATTAACGATGTATTTATTCCTCTTAAGCCACTTAGACAATTGGAAAT
TATCTCAGGCGAATATAATGATGTTATTAATGAAAAAGTTCATGTGAAAAATAAAGATAATTATTTACATTTTAAACTTA
AAAATATGTCTCATATTACTGATCCAATGATGAGTTTAAAACAAATTTATCCTAATACTTTAGCGCTGACGAATGAAACT
TTTAATTATAATGAAGAAAATAATGCTATAGAAATAAGTGAAAAAGATGACATGTCAATTATCGAAATGTTTTATAAACA
TATAACTGATAAAGAATTATCGGATATCCAATCTAAAAAGATAAAAAATATTTTAGAAAACGAATTGAGAAAGGAGGATT
AA

Upstream 100 bases:

>100_bases
CGACTTCTAAATCAGTCAATGAGTGGTTTTAATTTTACTTGAAAAGGTGAAATGATTATATTAAAATAAAAGCGAACAAA
TGTTCTATATGGAGGCAGTA

Downstream 100 bases:

>100_bases
TGAATGAAACCATTACATTTAAAGTTGAATAATTTCGGCCCCTTTTTAAAAGAAGAAATTGATTTTTCTAAAATTGATAA
TAATGAATTGTTTTTAATAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKIIHTADWHLGKILNGKQLLEDQAYILDMFVEKMKEEEPDIIVIAGDLYDTTYPSKDAIMLLEQAIGKLNLELRIPIIM
ISGNHDGKERLNYGASWFEHNQLFIRTDFTSINSPIEINGVNFYTLPYATVSEMKHYFEDDTIETHQQGITRCIETIAPE
IDEDAVNILISHLTVQGGKTSDSERPLTIGTVESVQKGVFDIFDYVMLGHLHHPFSIEDDKIKYSGSLLQYSFSEAGQAK
GYRRLTINDGIINDVFIPLKPLRQLEIISGEYNDVINEKVHVKNKDNYLHFKLKNMSHITDPMMSLKQIYPNTLALTNET
FNYNEENNAIEISEKDDMSIIEMFYKHITDKELSDIQSKKIKNILENELRKED

Sequences:

>Translated_373_residues
MKIIHTADWHLGKILNGKQLLEDQAYILDMFVEKMKEEEPDIIVIAGDLYDTTYPSKDAIMLLEQAIGKLNLELRIPIIM
ISGNHDGKERLNYGASWFEHNQLFIRTDFTSINSPIEINGVNFYTLPYATVSEMKHYFEDDTIETHQQGITRCIETIAPE
IDEDAVNILISHLTVQGGKTSDSERPLTIGTVESVQKGVFDIFDYVMLGHLHHPFSIEDDKIKYSGSLLQYSFSEAGQAK
GYRRLTINDGIINDVFIPLKPLRQLEIISGEYNDVINEKVHVKNKDNYLHFKLKNMSHITDPMMSLKQIYPNTLALTNET
FNYNEENNAIEISEKDDMSIIEMFYKHITDKELSDIQSKKIKNILENELRKED
>Mature_373_residues
MKIIHTADWHLGKILNGKQLLEDQAYILDMFVEKMKEEEPDIIVIAGDLYDTTYPSKDAIMLLEQAIGKLNLELRIPIIM
ISGNHDGKERLNYGASWFEHNQLFIRTDFTSINSPIEINGVNFYTLPYATVSEMKHYFEDDTIETHQQGITRCIETIAPE
IDEDAVNILISHLTVQGGKTSDSERPLTIGTVESVQKGVFDIFDYVMLGHLHHPFSIEDDKIKYSGSLLQYSFSEAGQAK
GYRRLTINDGIINDVFIPLKPLRQLEIISGEYNDVINEKVHVKNKDNYLHFKLKNMSHITDPMMSLKQIYPNTLALTNET
FNYNEENNAIEISEKDDMSIIEMFYKHITDKELSDIQSKKIKNILENELRKED

Specific function: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand

COG id: COG0420

COG function: function code L; DNA repair exonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sbcD family

Homologues:

Organism=Escherichia coli, GI1786598, Length=415, Percent_Identity=23.855421686747, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SBCD_STAA1 (A7X202)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441924.1
- ProteinModelPortal:   A7X202
- SMR:   A7X202
- STRING:   A7X202
- EnsemblBacteria:   EBSTAT00000005393
- GeneID:   5561529
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1334
- eggNOG:   COG0420
- GeneTree:   EBGT00050000024850
- HOGENOM:   HBG677966
- OMA:   GGAYTVA
- ProtClustDB:   CLSK885289
- BioCyc:   SAUR418127:SAHV_1334-MONOMER
- InterPro:   IPR004843
- InterPro:   IPR004593
- TIGRFAMs:   TIGR00619

Pfam domain/function: PF00149 Metallophos

EC number: NA

Molecular weight: Translated: 42968; Mature: 42968

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIHTADWHLGKILNGKQLLEDQAYILDMFVEKMKEEEPDIIVIAGDLYDTTYPSKDAI
CCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHH
MLLEQAIGKLNLELRIPIIMISGNHDGKERLNYGASWFEHNQLFIRTDFTSINSPIEING
HHHHHHHHHCCEEEEEEEEEEECCCCCHHHHHCCCCEEECCEEEEEECCCCCCCCEEECC
VNFYTLPYATVSEMKHYFEDDTIETHQQGITRCIETIAPEIDEDAVNILISHLTVQGGKT
EEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEECCCCC
SDSERPLTIGTVESVQKGVFDIFDYVMLGHLHHPFSIEDDKIKYSGSLLQYSFSEAGQAK
CCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCEEEEEHHHHHCCC
GYRRLTINDGIINDVFIPLKPLRQLEIISGEYNDVINEKVHVKNKDNYLHFKLKNMSHIT
CEEEEEECCCCCCCEECCCCCCCCEEEECCCHHHHCCCEEEEECCCCEEEEEECCCHHHH
DPMMSLKQIYPNTLALTNETFNYNEENNAIEISEKDDMSIIEMFYKHITDKELSDIQSKK
HHHHHHHHHCCCEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHH
IKNILENELRKED
HHHHHHHHHHCCC
>Mature Secondary Structure
MKIIHTADWHLGKILNGKQLLEDQAYILDMFVEKMKEEEPDIIVIAGDLYDTTYPSKDAI
CCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHH
MLLEQAIGKLNLELRIPIIMISGNHDGKERLNYGASWFEHNQLFIRTDFTSINSPIEING
HHHHHHHHHCCEEEEEEEEEEECCCCCHHHHHCCCCEEECCEEEEEECCCCCCCCEEECC
VNFYTLPYATVSEMKHYFEDDTIETHQQGITRCIETIAPEIDEDAVNILISHLTVQGGKT
EEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEECCCCC
SDSERPLTIGTVESVQKGVFDIFDYVMLGHLHHPFSIEDDKIKYSGSLLQYSFSEAGQAK
CCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCEEEEEHHHHHCCC
GYRRLTINDGIINDVFIPLKPLRQLEIISGEYNDVINEKVHVKNKDNYLHFKLKNMSHIT
CEEEEEECCCCCCCEECCCCCCCCEEEECCCHHHHCCCEEEEECCCCEEEEEECCCHHHH
DPMMSLKQIYPNTLALTNETFNYNEENNAIEISEKDDMSIIEMFYKHITDKELSDIQSKK
HHHHHHHHHCCCEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHH
IKNILENELRKED
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA