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The map label for this gene is tkt

Identifier: 15926923

GI number: 15926923

Start: 1338627

End: 1340615

Strand: Direct

Name: tkt

Synonym: SA1177

Alternate gene names: 15926923

Gene position: 1338627-1340615 (Clockwise)

Preceding gene: 15926922

Following gene: 15926924

Centisome position: 47.56

GC content: 36.0

Gene sequence:

>1989_bases
ATGTTTAATGAAAAAGATCAATTAGCTGTTGATACGCTACGTGCACTAAGTATCGACACAATCGAAAAAGCGAATTCTGG
TCATCCAGGATTACCTATGGGAGCTGCCCCAATGGCTTACACTTTGTGGACACGTCATCTGAATTTTAATCCACAATCTA
AAGATTACTTCAATAGAGACCGTTTCGTATTATCGGCAGGGCATGGTTCAGCATTATTGTATAGCTTGTTACATGTTTCT
GGTAGTTTAGAATTAGAAGAATTAAAGCAATTTAGACAATGGGGTTCTAAAACACCAGGCCATCCTGAATACAGACATAC
TGATGGTGTAGAAGTTACTACTGGACCACTTGGACAAGGTTTTGCTATGTCAGTAGGATTAGCTTTAGCAGAAGATCACC
TAGCAGGGAAATTTAATAAAGAAGGATATAATGTTGTAGATCATTACACATATGTATTAGCTTCTGACGGTGATTTAATG
GAAGGTATATCGCATGAAGCAGCTTCATTTGCTGGACATAATAAATTAAGTAAATTAGTTGTTTTATACGATTCAAATGA
TATTTCATTAGATGGCGAATTAAACAAAGCTTTTTCTGAAAACACAAAAGCTCGTTTTGAAGCATATGGTTGGAATTACT
TACTAGTTAAAGATGGTAATGATTTAGAAGAAATTGATAAAGCGATTACTACAGCTAAATCTCAAGAAGGACCAACGATT
ATTGAAGTTAAAACAACAATCGGATTTGGTTCACCGAATAAAGCAGGAACTAATGGTGTTCATGGGGCACCTTTAGGTGA
AGTTGAAAGAAAATTAACATTCGAAAATTACGGTTTAGATCCTGAAAAACGTTTTAATGTTTCAGAAGAGGTATACGAAA
TTTTCCAAAATACTATGTTAAAACGTGCTAATGAAGATGAATCTCAATGGAATTCATTATTAGAAAAATATGCAGAAACA
TATCCTGAATTAGCAGAAGAATTTAAATTAGCGATTAGTGGTAAATTGCCTAAAAATTATAAGGATGAATTACCACGTTT
TGAACTGGGTCATAATGGTGCATCTCGTGCTGATTCTGGTACTGTTATTCAAGCAATCAGTAAAACTGTCCCTTCATTCT
TTGGTGGATCAGCAGACCTTGCTGGTTCAAACAAATCCAATGTAAATGATGCAACAGATTATAGTTCTGAAACACCTGAA
GGTAAAAATGTGTGGTTTGGTGTACGTGAATTTGCTATGGGTGCTGCTGTAAATGGTATGGCTGCACATGGAGGTTTACA
TCCATATGGTGCAACATTCTTCGTATTTAGTGATTATTTAAAACCAGCGTTACGTTTATCATCAATTATGGGATTAAATG
CAACGTTCATCTTCACACATGATTCAATTGCAGTAGGTGAAGATGGTCCTACTCATGAACCAATTGAACAATTAGCTGGA
TTAAGAGCTATTCCAAATATGAATGTTATCCGTCCTGCTGATGGTAATGAAACAAGAGTAGCATGGGAAGTTGCCTTAGA
ATCTGAATCTACACCTACTTCATTAGTATTGACACGTCAAAACTTACCGGTTTTAGATGTACCAGAAGATGTAGTTGAAG
AAGGCGTTCGAAAAGGTGCCTATACAGTTTATGGCTCTGAAGAGACACCAGAATTCCTATTATTAGCTTCAGGTTCAGAA
GTTAGTCTTGCAGTTGAAGCTGCTAAAGATCTTGAAAAACAAGGTAAATCAGTGCGTGTTGTTTCAATGCCTAACTGGAA
TGCATTTGAACAACAATCTGAAGAATATAAAGAATCAGTTATTCCATCAAGCGTAACAAAACGTGTTGCGATTGAAATGG
CTTCACCGCTTGGATGGCATAAATATGTAGGTACTGCAGGTAAAGTTATTGCTATTGACGGCTTTGGCGCAAGTGCACCT
GGCGATTTAGTAGTTGAAAAATATGGATTTACTAAAGAAAATATCTTAAACCAAGTTATGAGCTTATAA

Upstream 100 bases:

>100_bases
TTTCTGACATTATAACTTGAAATAAGTATTTTACTTATCTTTTTATTTTAAAATAAGTTATAATGTATTTGATAAAATTG
AAGAAGGGAAGATACACAAG

Downstream 100 bases:

>100_bases
GAATAATTTATAAAGCGAGTATGTTTAGAAGTCTAGGATGCATAATCTTAGGCTTCTTTTAAAGTGTTGAAATTTAGAGT
ATAGCACTTAAACTACATCA

Product: transketolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 662; Mature: 662

Protein sequence:

>662_residues
MFNEKDQLAVDTLRALSIDTIEKANSGHPGLPMGAAPMAYTLWTRHLNFNPQSKDYFNRDRFVLSAGHGSALLYSLLHVS
GSLELEELKQFRQWGSKTPGHPEYRHTDGVEVTTGPLGQGFAMSVGLALAEDHLAGKFNKEGYNVVDHYTYVLASDGDLM
EGISHEAASFAGHNKLSKLVVLYDSNDISLDGELNKAFSENTKARFEAYGWNYLLVKDGNDLEEIDKAITTAKSQEGPTI
IEVKTTIGFGSPNKAGTNGVHGAPLGEVERKLTFENYGLDPEKRFNVSEEVYEIFQNTMLKRANEDESQWNSLLEKYAET
YPELAEEFKLAISGKLPKNYKDELPRFELGHNGASRADSGTVIQAISKTVPSFFGGSADLAGSNKSNVNDATDYSSETPE
GKNVWFGVREFAMGAAVNGMAAHGGLHPYGATFFVFSDYLKPALRLSSIMGLNATFIFTHDSIAVGEDGPTHEPIEQLAG
LRAIPNMNVIRPADGNETRVAWEVALESESTPTSLVLTRQNLPVLDVPEDVVEEGVRKGAYTVYGSEETPEFLLLASGSE
VSLAVEAAKDLEKQGKSVRVVSMPNWNAFEQQSEEYKESVIPSSVTKRVAIEMASPLGWHKYVGTAGKVIAIDGFGASAP
GDLVVEKYGFTKENILNQVMSL

Sequences:

>Translated_662_residues
MFNEKDQLAVDTLRALSIDTIEKANSGHPGLPMGAAPMAYTLWTRHLNFNPQSKDYFNRDRFVLSAGHGSALLYSLLHVS
GSLELEELKQFRQWGSKTPGHPEYRHTDGVEVTTGPLGQGFAMSVGLALAEDHLAGKFNKEGYNVVDHYTYVLASDGDLM
EGISHEAASFAGHNKLSKLVVLYDSNDISLDGELNKAFSENTKARFEAYGWNYLLVKDGNDLEEIDKAITTAKSQEGPTI
IEVKTTIGFGSPNKAGTNGVHGAPLGEVERKLTFENYGLDPEKRFNVSEEVYEIFQNTMLKRANEDESQWNSLLEKYAET
YPELAEEFKLAISGKLPKNYKDELPRFELGHNGASRADSGTVIQAISKTVPSFFGGSADLAGSNKSNVNDATDYSSETPE
GKNVWFGVREFAMGAAVNGMAAHGGLHPYGATFFVFSDYLKPALRLSSIMGLNATFIFTHDSIAVGEDGPTHEPIEQLAG
LRAIPNMNVIRPADGNETRVAWEVALESESTPTSLVLTRQNLPVLDVPEDVVEEGVRKGAYTVYGSEETPEFLLLASGSE
VSLAVEAAKDLEKQGKSVRVVSMPNWNAFEQQSEEYKESVIPSSVTKRVAIEMASPLGWHKYVGTAGKVIAIDGFGASAP
GDLVVEKYGFTKENILNQVMSL
>Mature_662_residues
MFNEKDQLAVDTLRALSIDTIEKANSGHPGLPMGAAPMAYTLWTRHLNFNPQSKDYFNRDRFVLSAGHGSALLYSLLHVS
GSLELEELKQFRQWGSKTPGHPEYRHTDGVEVTTGPLGQGFAMSVGLALAEDHLAGKFNKEGYNVVDHYTYVLASDGDLM
EGISHEAASFAGHNKLSKLVVLYDSNDISLDGELNKAFSENTKARFEAYGWNYLLVKDGNDLEEIDKAITTAKSQEGPTI
IEVKTTIGFGSPNKAGTNGVHGAPLGEVERKLTFENYGLDPEKRFNVSEEVYEIFQNTMLKRANEDESQWNSLLEKYAET
YPELAEEFKLAISGKLPKNYKDELPRFELGHNGASRADSGTVIQAISKTVPSFFGGSADLAGSNKSNVNDATDYSSETPE
GKNVWFGVREFAMGAAVNGMAAHGGLHPYGATFFVFSDYLKPALRLSSIMGLNATFIFTHDSIAVGEDGPTHEPIEQLAG
LRAIPNMNVIRPADGNETRVAWEVALESESTPTSLVLTRQNLPVLDVPEDVVEEGVRKGAYTVYGSEETPEFLLLASGSE
VSLAVEAAKDLEKQGKSVRVVSMPNWNAFEQQSEEYKESVIPSSVTKRVAIEMASPLGWHKYVGTAGKVIAIDGFGASAP
GDLVVEKYGFTKENILNQVMSL

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family

Homologues:

Organism=Homo sapiens, GI205277463, Length=590, Percent_Identity=27.2881355932203, Blast_Score=163, Evalue=6e-40,
Organism=Homo sapiens, GI4507521, Length=590, Percent_Identity=27.2881355932203, Blast_Score=163, Evalue=6e-40,
Organism=Homo sapiens, GI133778974, Length=582, Percent_Identity=25.9450171821306, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI225637463, Length=502, Percent_Identity=23.5059760956175, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI225637461, Length=502, Percent_Identity=23.5059760956175, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI225637459, Length=502, Percent_Identity=23.5059760956175, Blast_Score=108, Evalue=2e-23,
Organism=Escherichia coli, GI48994911, Length=668, Percent_Identity=45.2095808383234, Blast_Score=585, Evalue=1e-168,
Organism=Escherichia coli, GI1788808, Length=653, Percent_Identity=45.7886676875957, Blast_Score=575, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI17539652, Length=576, Percent_Identity=27.6041666666667, Blast_Score=165, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6325331, Length=664, Percent_Identity=46.5361445783133, Blast_Score=573, Evalue=1e-164,
Organism=Saccharomyces cerevisiae, GI6319593, Length=668, Percent_Identity=42.814371257485, Blast_Score=533, Evalue=1e-152,
Organism=Drosophila melanogaster, GI45551847, Length=576, Percent_Identity=27.4305555555556, Blast_Score=171, Evalue=2e-42,
Organism=Drosophila melanogaster, GI45550715, Length=576, Percent_Identity=27.4305555555556, Blast_Score=171, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24666278, Length=578, Percent_Identity=27.681660899654, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24645119, Length=548, Percent_Identity=27.1897810218978, Blast_Score=157, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TKT_STAAC (Q5HG77)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_186230.1
- ProteinModelPortal:   Q5HG77
- SMR:   Q5HG77
- STRING:   Q5HG77
- EnsemblBacteria:   EBSTAT00000010296
- GeneID:   3237261
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL1377
- TIGR:   SACOL1377
- eggNOG:   COG0021
- GeneTree:   EBGT00050000024493
- HOGENOM:   HBG565885
- OMA:   ELANEFQ
- ProtClustDB:   CLSK885287
- BioCyc:   SAUR93062:SACOL1377-MONOMER
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474
- Gene3D:   G3DSA:3.40.50.920
- PANTHER:   PTHR11624:SF1
- SMART:   SM00861
- TIGRFAMs:   TIGR00232

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N; SSF52922 Transketo_C_like

EC number: =2.2.1.1

Molecular weight: Translated: 72251; Mature: 72251

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00801 TRANSKETOLASE_1; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNEKDQLAVDTLRALSIDTIEKANSGHPGLPMGAAPMAYTLWTRHLNFNPQSKDYFNRD
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHCCCCCCCCCCCCCCC
RFVLSAGHGSALLYSLLHVSGSLELEELKQFRQWGSKTPGHPEYRHTDGVEVTTGPLGQG
CEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCC
FAMSVGLALAEDHLAGKFNKEGYNVVDHYTYVLASDGDLMEGISHEAASFAGHNKLSKLV
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEE
VLYDSNDISLDGELNKAFSENTKARFEAYGWNYLLVKDGNDLEEIDKAITTAKSQEGPTI
EEECCCCEEECCCHHHHHHCCCCCEEEEECCEEEEEECCCCHHHHHHHHHHCCCCCCCEE
IEVKTTIGFGSPNKAGTNGVHGAPLGEVERKLTFENYGLDPEKRFNVSEEVYEIFQNTML
EEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHH
KRANEDESQWNSLLEKYAETYPELAEEFKLAISGKLPKNYKDELPRFELGHNGASRADSG
HHCCCCHHHHHHHHHHHHHHHHHHHHHHEEHCCCCCCCCHHHCCCCEECCCCCCCCCCCC
TVIQAISKTVPSFFGGSADLAGSNKSNVNDATDYSSETPEGKNVWFGVREFAMGAAVNGM
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCH
AAHGGLHPYGATFFVFSDYLKPALRLSSIMGLNATFIFTHDSIAVGEDGPTHEPIEQLAG
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCEEECCCCCCHHHHHHHHC
LRAIPNMNVIRPADGNETRVAWEVALESESTPTSLVLTRQNLPVLDVPEDVVEEGVRKGA
CCCCCCCCEEECCCCCCCEEEEEEEECCCCCCCEEEEEECCCCEECCCHHHHHHHHHCCC
YTVYGSEETPEFLLLASGSEVSLAVEAAKDLEKQGKSVRVVSMPNWNAFEQQSEEYKESV
EEEECCCCCCCEEEEECCCCEEEEHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHC
IPSSVTKRVAIEMASPLGWHKYVGTAGKVIAIDGFGASAPGDLVVEKYGFTKENILNQVM
CCHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHH
SL
CC
>Mature Secondary Structure
MFNEKDQLAVDTLRALSIDTIEKANSGHPGLPMGAAPMAYTLWTRHLNFNPQSKDYFNRD
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHCCCCCCCCCCCCCCC
RFVLSAGHGSALLYSLLHVSGSLELEELKQFRQWGSKTPGHPEYRHTDGVEVTTGPLGQG
CEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCC
FAMSVGLALAEDHLAGKFNKEGYNVVDHYTYVLASDGDLMEGISHEAASFAGHNKLSKLV
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEE
VLYDSNDISLDGELNKAFSENTKARFEAYGWNYLLVKDGNDLEEIDKAITTAKSQEGPTI
EEECCCCEEECCCHHHHHHCCCCCEEEEECCEEEEEECCCCHHHHHHHHHHCCCCCCCEE
IEVKTTIGFGSPNKAGTNGVHGAPLGEVERKLTFENYGLDPEKRFNVSEEVYEIFQNTML
EEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHH
KRANEDESQWNSLLEKYAETYPELAEEFKLAISGKLPKNYKDELPRFELGHNGASRADSG
HHCCCCHHHHHHHHHHHHHHHHHHHHHHEEHCCCCCCCCHHHCCCCEECCCCCCCCCCCC
TVIQAISKTVPSFFGGSADLAGSNKSNVNDATDYSSETPEGKNVWFGVREFAMGAAVNGM
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCH
AAHGGLHPYGATFFVFSDYLKPALRLSSIMGLNATFIFTHDSIAVGEDGPTHEPIEQLAG
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCEEECCCCCCHHHHHHHHC
LRAIPNMNVIRPADGNETRVAWEVALESESTPTSLVLTRQNLPVLDVPEDVVEEGVRKGA
CCCCCCCCEEECCCCCCCEEEEEEEECCCCCCCEEEEEECCCCEECCCHHHHHHHHHCCC
YTVYGSEETPEFLLLASGSEVSLAVEAAKDLEKQGKSVRVVSMPNWNAFEQQSEEYKESV
EEEECCCCCCCEEEEECCCCEEEEHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHC
IPSSVTKRVAIEMASPLGWHKYVGTAGKVIAIDGFGASAPGDLVVEKYGFTKENILNQVM
CCHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHH
SL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA