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The map label for this gene is katA

Identifier: 15926915

GI number: 15926915

Start: 1332093

End: 1333616

Strand: Direct

Name: katA

Synonym: SA1170

Alternate gene names: 15926915

Gene position: 1332093-1333616 (Clockwise)

Preceding gene: 15926912

Following gene: 15926916

Centisome position: 47.32

GC content: 36.09

Gene sequence:

>1524_bases
ATGACTATGTCACAACAAGACAAAAAGTTAACTGGTGTTTTTGGGCATCCAGTATCAGACCGAGAAAATAGTATGACAGC
AGGGCCTAGGGGACCTCTTTTAATGCAAGATATTTACTTTTTAGAGCAAATGTCTCAATTTGATAGAGAAGTAATACCAG
AACGTCGAATGCATGCCAAAGGTTCTGGTGCATTTGGGACATTTACTGTAACTAAAGATATAACAAAATATACGAATGCT
AAAATATTCTCTGAAATAGGTAAGCAAACCGAAATGTTTGCCCGTTTCTCTACTGTAGCAGGAGAACGTGGTGCTGCTGA
TGCGGAGCGTGACATTCGAGGATTTGCGTTAAAGTTCTACACTGAAGAAGGGAACTGGGATTTAGTAGGGAATAACACAC
CAGTATTCTTCTTTAGAGATCCAAAGTTATTTGTTAGTTTAAATCGTGCGGTGAAACGAGATCCTAGAACAAATATGAGA
GATGCACAAAATAACTGGGATTTCTGGACGGGTCTTCCAGAAGCATTGCACCAAGTAACGATCTTAATGTCAGATAGAGG
GATTCCTAAAGATTTACGTCATATGCATGGGTTCGGTTCTCACACATACTCTATGTATAATGATTCTGGTGAACGTGTTT
GGGTTAAATTCCATTTTAGAACGCAACAAGGTATTGAAAACTTAACTGATGAAGAAGCTGCTGAAATTATAGCTACAGAT
CGTGATTCATCTCAACGCGATTTATTCGAAGCCATTGAAAAAGGTGATTATCCAAAATGGACAATGTATATTCAAGTAAT
GACTGAGGAACAAGCTAAAAACCATAAAGATAATCCATTTGATTTAACAAAAGTATGGTATCACGATGAGTATCCTCTAA
TTGAAGTTGGAGAGTTTGAATTAAATAGAAATCCAGATAATTACTTTATGGATGTTGAACAAGCTGCGTTTGCACCAACT
AATATTATTCCAGGATTAGATTTTTCTCCAGACAAAATGTTGCAAGGGCGTTTATTCTCATATGGCGATGCGCAAAGATA
TCGATTAGGAGTTAATCATTGGCAGATTCCTGTAAACCAACCTAAAGGTGTTGGTATTGAAAATATTTGTCCTTTTAGTA
GAGATGGTCAAATGCGCGTAGTTGACAATAACCAAGGTGGAGGAACACATTATTATCCAAATAACCATGGTAAATTTGAT
TCTCAACCTGAATATAAAAAGCCACCATTCCCAACTGATGGATACGGCTATGAATATAATCAACGTCAAGATGATGATAA
TTATTTTGAACAACCAGGTAAATTGTTTAGATTACAATCAGAGGACGCTAAAGAAAGAATTTTTACAAATACAGCAAATG
CAATGGAAGGCGTAACGGATGATGTTAAACGACGTCATATTCGTCATTGTTACAAAGCTGACCCAGAATATGGTAAAGGT
GTTGCAAAAGCATTAGGTATTGATATAAATTCTATTGATCTTGAAACTGAAAATGATGAAACATACGAAAACTTTGAAAA
ATAA

Upstream 100 bases:

>100_bases
TTTTCTGATTTTTTAATCATCTTGAGCATGTTTAATTGTAATTTTGATGGGGTTAAATTATAATATGTATTAAATTATAA
TTATTATAAATTGTGGAGGG

Downstream 100 bases:

>100_bases
ATTTGATATGTAGTTTCTATATTGCGTAGTTGAGCAGTTTATGATATCATAATAAATCGTAAAGATTCCTAACAAGAGAG
GGTGTTTAACGTGCGCGTAA

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 507; Mature: 506

Protein sequence:

>507_residues
MTMSQQDKKLTGVFGHPVSDRENSMTAGPRGPLLMQDIYFLEQMSQFDREVIPERRMHAKGSGAFGTFTVTKDITKYTNA
KIFSEIGKQTEMFARFSTVAGERGAADAERDIRGFALKFYTEEGNWDLVGNNTPVFFFRDPKLFVSLNRAVKRDPRTNMR
DAQNNWDFWTGLPEALHQVTILMSDRGIPKDLRHMHGFGSHTYSMYNDSGERVWVKFHFRTQQGIENLTDEEAAEIIATD
RDSSQRDLFEAIEKGDYPKWTMYIQVMTEEQAKNHKDNPFDLTKVWYHDEYPLIEVGEFELNRNPDNYFMDVEQAAFAPT
NIIPGLDFSPDKMLQGRLFSYGDAQRYRLGVNHWQIPVNQPKGVGIENICPFSRDGQMRVVDNNQGGGTHYYPNNHGKFD
SQPEYKKPPFPTDGYGYEYNQRQDDDNYFEQPGKLFRLQSEDAKERIFTNTANAMEGVTDDVKRRHIRHCYKADPEYGKG
VAKALGIDINSIDLETENDETYENFEK

Sequences:

>Translated_507_residues
MTMSQQDKKLTGVFGHPVSDRENSMTAGPRGPLLMQDIYFLEQMSQFDREVIPERRMHAKGSGAFGTFTVTKDITKYTNA
KIFSEIGKQTEMFARFSTVAGERGAADAERDIRGFALKFYTEEGNWDLVGNNTPVFFFRDPKLFVSLNRAVKRDPRTNMR
DAQNNWDFWTGLPEALHQVTILMSDRGIPKDLRHMHGFGSHTYSMYNDSGERVWVKFHFRTQQGIENLTDEEAAEIIATD
RDSSQRDLFEAIEKGDYPKWTMYIQVMTEEQAKNHKDNPFDLTKVWYHDEYPLIEVGEFELNRNPDNYFMDVEQAAFAPT
NIIPGLDFSPDKMLQGRLFSYGDAQRYRLGVNHWQIPVNQPKGVGIENICPFSRDGQMRVVDNNQGGGTHYYPNNHGKFD
SQPEYKKPPFPTDGYGYEYNQRQDDDNYFEQPGKLFRLQSEDAKERIFTNTANAMEGVTDDVKRRHIRHCYKADPEYGKG
VAKALGIDINSIDLETENDETYENFEK
>Mature_506_residues
TMSQQDKKLTGVFGHPVSDRENSMTAGPRGPLLMQDIYFLEQMSQFDREVIPERRMHAKGSGAFGTFTVTKDITKYTNAK
IFSEIGKQTEMFARFSTVAGERGAADAERDIRGFALKFYTEEGNWDLVGNNTPVFFFRDPKLFVSLNRAVKRDPRTNMRD
AQNNWDFWTGLPEALHQVTILMSDRGIPKDLRHMHGFGSHTYSMYNDSGERVWVKFHFRTQQGIENLTDEEAAEIIATDR
DSSQRDLFEAIEKGDYPKWTMYIQVMTEEQAKNHKDNPFDLTKVWYHDEYPLIEVGEFELNRNPDNYFMDVEQAAFAPTN
IIPGLDFSPDKMLQGRLFSYGDAQRYRLGVNHWQIPVNQPKGVGIENICPFSRDGQMRVVDNNQGGGTHYYPNNHGKFDS
QPEYKKPPFPTDGYGYEYNQRQDDDNYFEQPGKLFRLQSEDAKERIFTNTANAMEGVTDDVKRRHIRHCYKADPEYGKGV
AKALGIDINSIDLETENDETYENFEK

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=482, Percent_Identity=50.8298755186722, Blast_Score=491, Evalue=1e-139,
Organism=Escherichia coli, GI48994891, Length=503, Percent_Identity=39.9602385685885, Blast_Score=323, Evalue=2e-89,
Organism=Caenorhabditis elegans, GI71998444, Length=477, Percent_Identity=50.5241090146751, Blast_Score=475, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI25151141, Length=483, Percent_Identity=48.0331262939959, Blast_Score=457, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI25147792, Length=477, Percent_Identity=48.0083857442348, Blast_Score=456, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6320462, Length=404, Percent_Identity=50, Blast_Score=382, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6321525, Length=530, Percent_Identity=35.6603773584906, Blast_Score=317, Evalue=4e-87,
Organism=Drosophila melanogaster, GI17981717, Length=479, Percent_Identity=49.4780793319415, Blast_Score=474, Evalue=1e-134,
Organism=Drosophila melanogaster, GI19920968, Length=485, Percent_Identity=44.9484536082474, Blast_Score=434, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 58613; Mature: 58482

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMSQQDKKLTGVFGHPVSDRENSMTAGPRGPLLMQDIYFLEQMSQFDREVIPERRMHAK
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCC
GSGAFGTFTVTKDITKYTNAKIFSEIGKQTEMFARFSTVAGERGAADAERDIRGFALKFY
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCEEEEEEE
TEEGNWDLVGNNTPVFFFRDPKLFVSLNRAVKRDPRTNMRDAQNNWDFWTGLPEALHQVT
EECCCEEEECCCCCEEEEECCCEEEEECHHHHCCCCCCCCCCCCCCCHHCCHHHHHHHEE
ILMSDRGIPKDLRHMHGFGSHTYSMYNDSGERVWVKFHFRTQQGIENLTDEEAAEIIATD
EEECCCCCCHHHHHHCCCCCCEEEEECCCCCEEEEEEEEECHHHHHHCCHHHHHHHEECC
RDSSQRDLFEAIEKGDYPKWTMYIQVMTEEQAKNHKDNPFDLTKVWYHDEYPLIEVGEFE
CCCHHHHHHHHHHCCCCCCEEEEEEEEEHHHHHCCCCCCCEEEEEEECCCCCEEEECCEE
LNRNPDNYFMDVEQAAFAPTNIIPGLDFSPDKMLQGRLFSYGDAQRYRLGVNHWQIPVNQ
ECCCCCCEEEEHHHHHCCCCCCCCCCCCCHHHHHHCHHHCCCCCCCEEECCCEEEECCCC
PKGVGIENICPFSRDGQMRVVDNNQGGGTHYYPNNHGKFDSQPEYKKPPFPTDGYGYEYN
CCCCCHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
QRQDDDNYFEQPGKLFRLQSEDAKERIFTNTANAMEGVTDDVKRRHIRHCYKADPEYGKG
CCCCCCHHHHCCCCEEEECCCCHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHCCCHHHHH
VAKALGIDINSIDLETENDETYENFEK
HHHHHCCCCEEEEEECCCCHHHHHHCC
>Mature Secondary Structure 
TMSQQDKKLTGVFGHPVSDRENSMTAGPRGPLLMQDIYFLEQMSQFDREVIPERRMHAK
CCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCC
GSGAFGTFTVTKDITKYTNAKIFSEIGKQTEMFARFSTVAGERGAADAERDIRGFALKFY
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCEEEEEEE
TEEGNWDLVGNNTPVFFFRDPKLFVSLNRAVKRDPRTNMRDAQNNWDFWTGLPEALHQVT
EECCCEEEECCCCCEEEEECCCEEEEECHHHHCCCCCCCCCCCCCCCHHCCHHHHHHHEE
ILMSDRGIPKDLRHMHGFGSHTYSMYNDSGERVWVKFHFRTQQGIENLTDEEAAEIIATD
EEECCCCCCHHHHHHCCCCCCEEEEECCCCCEEEEEEEEECHHHHHHCCHHHHHHHEECC
RDSSQRDLFEAIEKGDYPKWTMYIQVMTEEQAKNHKDNPFDLTKVWYHDEYPLIEVGEFE
CCCHHHHHHHHHHCCCCCCEEEEEEEEEHHHHHCCCCCCCEEEEEEECCCCCEEEECCEE
LNRNPDNYFMDVEQAAFAPTNIIPGLDFSPDKMLQGRLFSYGDAQRYRLGVNHWQIPVNQ
ECCCCCCEEEEHHHHHCCCCCCCCCCCCCHHHHHHCHHHCCCCCCCEEECCCEEEECCCC
PKGVGIENICPFSRDGQMRVVDNNQGGGTHYYPNNHGKFDSQPEYKKPPFPTDGYGYEYN
CCCCCHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
QRQDDDNYFEQPGKLFRLQSEDAKERIFTNTANAMEGVTDDVKRRHIRHCYKADPEYGKG
CCCCCCHHHHCCCCEEEECCCCHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHCCCHHHHH
VAKALGIDINSIDLETENDETYENFEK
HHHHHCCCCEEEEEECCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA