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The map label for this gene is glnA

Identifier: 15926892

GI number: 15926892

Start: 1307165

End: 1308505

Strand: Direct

Name: glnA

Synonym: SA1150

Alternate gene names: 15926892

Gene position: 1307165-1308505 (Clockwise)

Preceding gene: 15926891

Following gene: 15926893

Centisome position: 46.44

GC content: 35.05

Gene sequence:

>1341_bases
ATGCCAAAACGTACTTTCACTAAAGAAGACATTCGTAAATTTGCAGAAGAGGAAAATGTAAGATATTTAAGATTACAATT
CACTGATATTTTAGGAACAATTAAAAATGTTGAAGTGCCTGTAAGCCAATTAGAAAAAGTACTTGATAACGAAATGATGT
TTGACGGTTCTTCTATCGAAGGTTTCGTACGTATCGAAGAATCAGATATGTACTTACATCCAGATTTAGATACTTGGGTA
ATCTTCCCATGGACTGCTGGACAAGGTAAAGTTGCACGTTTAATTTGTGATGTATATAAAACAGATGGAACACCATTTGA
AGGGGATCCTCGTGCAAACTTAAAACGTGTATTAAAAGAAATGGAAGATTTAGGCTTCACAGACTTTAACCTAGGGCCTG
AACCAGAATTCTTCTTGTTTAAGTTGGATGAAAAAGGGGAACCAACTTTAGAACTTAATGATGATGGTGGATATTTCGAT
TTAGCACCTACAGATTTAGGTGAAAACTGTCGTCGTGATATTGTTTTAGAATTAGAGGATATGGGCTTCGATATTGAAGC
TAGTCACCATGAAGTTGCCCCTGGTCAACATGAAATTGACTTTAAATATGCAGATGCTGTTACAGCATGTGATAATATCC
AAACATTTAAATTGGTTGTTAAAACAATCGCACGTAAACATAATTTACACGCAACATTTATGCCTAAACCATTATTCGGT
GTGAATGGTAGCGGTATGCACTTTAACGTTTCATTATTCAAAGGTAAAGAAAATGCATTCTTTGATCCAAATACTGAAAT
GGGCTTAACGGAAACTGCATATCAATTTACAGCAGGTGTGCTTAAAAATGCACGCGGATTTACTGCTGTATGTAACCCGT
TAGTAAACTCATATAAACGTTTAGTACCTGGTTATGAAGCACCATGTTATATTGCATGGAGTGGTAAAAACCGTTCACCA
TTAATCCGTGTACCATCTTCAAGAGGATTATCTACTCGTATCGAAGTACGTTCAGTAGATCCAGCTGCAAACCCATACAT
GGCGTTAGCTGCAATCTTAGAAGCTGGACTAGATGGTATTAAAAATAAATTAAAAGTTCCAGAACCAGTTAACCAAAATA
TTTACGAAATGAACCGTGAAGAACGTGAAGCAGTAGGCATTCAAGACTTACCTTCAACACTTTATACTGCATTAAAAGCA
ATGCGTGAAAATGAAGTTATTAAAAAAGCTTTAGGAAATCATATCTATAATCAATTTATTAATTCAAAATCAATTGAATG
GGATTACTACAGAACTCAAGTATCTGAATGGGAAAGAGATCAGTACATGAAGCAATATTAA

Upstream 100 bases:

>100_bases
GATGATTGTAGATGCCACGCAAAAGCCTATTGGAGAAACTTTGCCAATAAATCGTGGTGATTTATCCCGATTTATTAAAT
AAAATTTGGAGGATTTTAAA

Downstream 100 bases:

>100_bases
TACGCTAAACAATGATGGGAAATCAGTAATATCAAGGGCTAGAGCGTTTTGCTTTAGCTCTTTTTTGATTTGGAAAGATG
GGATTTCACTTGACCACTTT

Product: glutamine-ammonia ligase

Products: NA

Alternate protein names: GS; Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MPKRTFTKEDIRKFAEEENVRYLRLQFTDILGTIKNVEVPVSQLEKVLDNEMMFDGSSIEGFVRIEESDMYLHPDLDTWV
IFPWTAGQGKVARLICDVYKTDGTPFEGDPRANLKRVLKEMEDLGFTDFNLGPEPEFFLFKLDEKGEPTLELNDDGGYFD
LAPTDLGENCRRDIVLELEDMGFDIEASHHEVAPGQHEIDFKYADAVTACDNIQTFKLVVKTIARKHNLHATFMPKPLFG
VNGSGMHFNVSLFKGKENAFFDPNTEMGLTETAYQFTAGVLKNARGFTAVCNPLVNSYKRLVPGYEAPCYIAWSGKNRSP
LIRVPSSRGLSTRIEVRSVDPAANPYMALAAILEAGLDGIKNKLKVPEPVNQNIYEMNREEREAVGIQDLPSTLYTALKA
MRENEVIKKALGNHIYNQFINSKSIEWDYYRTQVSEWERDQYMKQY

Sequences:

>Translated_446_residues
MPKRTFTKEDIRKFAEEENVRYLRLQFTDILGTIKNVEVPVSQLEKVLDNEMMFDGSSIEGFVRIEESDMYLHPDLDTWV
IFPWTAGQGKVARLICDVYKTDGTPFEGDPRANLKRVLKEMEDLGFTDFNLGPEPEFFLFKLDEKGEPTLELNDDGGYFD
LAPTDLGENCRRDIVLELEDMGFDIEASHHEVAPGQHEIDFKYADAVTACDNIQTFKLVVKTIARKHNLHATFMPKPLFG
VNGSGMHFNVSLFKGKENAFFDPNTEMGLTETAYQFTAGVLKNARGFTAVCNPLVNSYKRLVPGYEAPCYIAWSGKNRSP
LIRVPSSRGLSTRIEVRSVDPAANPYMALAAILEAGLDGIKNKLKVPEPVNQNIYEMNREEREAVGIQDLPSTLYTALKA
MRENEVIKKALGNHIYNQFINSKSIEWDYYRTQVSEWERDQYMKQY
>Mature_445_residues
PKRTFTKEDIRKFAEEENVRYLRLQFTDILGTIKNVEVPVSQLEKVLDNEMMFDGSSIEGFVRIEESDMYLHPDLDTWVI
FPWTAGQGKVARLICDVYKTDGTPFEGDPRANLKRVLKEMEDLGFTDFNLGPEPEFFLFKLDEKGEPTLELNDDGGYFDL
APTDLGENCRRDIVLELEDMGFDIEASHHEVAPGQHEIDFKYADAVTACDNIQTFKLVVKTIARKHNLHATFMPKPLFGV
NGSGMHFNVSLFKGKENAFFDPNTEMGLTETAYQFTAGVLKNARGFTAVCNPLVNSYKRLVPGYEAPCYIAWSGKNRSPL
IRVPSSRGLSTRIEVRSVDPAANPYMALAAILEAGLDGIKNKLKVPEPVNQNIYEMNREEREAVGIQDLPSTLYTALKAM
RENEVIKKALGNHIYNQFINSKSIEWDYYRTQVSEWERDQYMKQY

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=453, Percent_Identity=24.9448123620309, Blast_Score=126, Evalue=4e-29,
Organism=Escherichia coli, GI1790301, Length=439, Percent_Identity=39.8633257403189, Blast_Score=274, Evalue=9e-75,
Organism=Escherichia coli, GI87081870, Length=460, Percent_Identity=27.8260869565217, Blast_Score=147, Evalue=2e-36,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 50855; Mature: 50724

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKRTFTKEDIRKFAEEENVRYLRLQFTDILGTIKNVEVPVSQLEKVLDNEMMFDGSSIE
CCCCCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHEEECCCCCC
GFVRIEESDMYLHPDLDTWVIFPWTAGQGKVARLICDVYKTDGTPFEGDPRANLKRVLKE
EEEEEECCCEEECCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
MEDLGFTDFNLGPEPEFFLFKLDEKGEPTLELNDDGGYFDLAPTDLGENCRRDIVLELED
HHHCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCCEEECCCCCCCCCCCCCEEEEEHH
MGFDIEASHHEVAPGQHEIDFKYADAVTACDNIQTFKLVVKTIARKHNLHATFMPKPLFG
CCCEEECCCCCCCCCCCCCCEEHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCCCC
VNGSGMHFNVSLFKGKENAFFDPNTEMGLTETAYQFTAGVLKNARGFTAVCNPLVNSYKR
CCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LVPGYEAPCYIAWSGKNRSPLIRVPSSRGLSTRIEVRSVDPAANPYMALAAILEAGLDGI
HCCCCCCCEEEEECCCCCCCEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHH
KNKLKVPEPVNQNIYEMNREEREAVGIQDLPSTLYTALKAMRENEVIKKALGNHIYNQFI
HHCCCCCCCCCCHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSKSIEWDYYRTQVSEWERDQYMKQY
CCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PKRTFTKEDIRKFAEEENVRYLRLQFTDILGTIKNVEVPVSQLEKVLDNEMMFDGSSIE
CCCCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHEEECCCCCC
GFVRIEESDMYLHPDLDTWVIFPWTAGQGKVARLICDVYKTDGTPFEGDPRANLKRVLKE
EEEEEECCCEEECCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
MEDLGFTDFNLGPEPEFFLFKLDEKGEPTLELNDDGGYFDLAPTDLGENCRRDIVLELED
HHHCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCCEEECCCCCCCCCCCCCEEEEEHH
MGFDIEASHHEVAPGQHEIDFKYADAVTACDNIQTFKLVVKTIARKHNLHATFMPKPLFG
CCCEEECCCCCCCCCCCCCCEEHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCCCC
VNGSGMHFNVSLFKGKENAFFDPNTEMGLTETAYQFTAGVLKNARGFTAVCNPLVNSYKR
CCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LVPGYEAPCYIAWSGKNRSPLIRVPSSRGLSTRIEVRSVDPAANPYMALAAILEAGLDGI
HCCCCCCCEEEEECCCCCCCEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHH
KNKLKVPEPVNQNIYEMNREEREAVGIQDLPSTLYTALKAMRENEVIKKALGNHIYNQFI
HHCCCCCCCCCCHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSKSIEWDYYRTQVSEWERDQYMKQY
CCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA