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The map label for this gene is pgsA

Identifier: 15926866

GI number: 15926866

Start: 1278452

End: 1279030

Strand: Direct

Name: pgsA

Synonym: SA1126

Alternate gene names: 15926866

Gene position: 1278452-1279030 (Clockwise)

Preceding gene: 15926865

Following gene: 15926867

Centisome position: 45.42

GC content: 30.57

Gene sequence:

>579_bases
ATGAATATTCCGAACCAGATTACGGTTTTTAGAGTAGTGTTAATACCAGTTTTTATATTGTTTGCGTTAGTTGATTTTGG
ATTTGGCAATGTGTCATTTCTAGGAGGATATGAAATAAGAATTGAGTTATTAATCAGTGGTTTTATTTTTATATTGGCTT
CCCTTAGCGATTTTGTTGATGGTTATTTAGCTAGAAAATGGAATTTAGTTACAAATATGGGGAAATTTTTGGATCCATTA
GCGGATAAATTATTAGTTGCAAGTGCTTTAATTGTACTTGTGCAACTAGGACTAACAAATTCTGTAGTAGCAATCATTAT
TATTGCCAGAGAATTTGCCGTAACTGGTTTACGTTTACTACAAATTGAACAAGGATTTGTAAGTGCAGCTGGTCAATTAG
GTAAAATTAAAACAGCAGTTACTATGGTAGCAATTACTTGGTTGTTATTAGGTGATCCATTGGCAACATTGATTGGTTTG
TCATTAGGACAAATTTTATTATACATTGGCGTTATTTTTACTATCTTATCTGGTATTGAATACTTTTATAAAGGTAGAGA
TGTTTTTAAACAAAAATAA

Upstream 100 bases:

>100_bases
AGTAATCATGGGTATTACAGTTTTAATAACTTTATTGTTATGGATCATGTTAGTTTTAATATTTTAACAGAAATAAATTA
GTGAGAAATGAGGATGTATA

Downstream 100 bases:

>100_bases
ATATTTGTTTATACTAGATTTCATTTTCATATGGAATCTAGTTTTTTTAATCCCAATTTTAGAAATTAGCCACGCAATTG
TTTATAATGATATATTGTAA

Product: phosphatidylglycerophosphate synthase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MNIPNQITVFRVVLIPVFILFALVDFGFGNVSFLGGYEIRIELLISGFIFILASLSDFVDGYLARKWNLVTNMGKFLDPL
ADKLLVASALIVLVQLGLTNSVVAIIIIAREFAVTGLRLLQIEQGFVSAAGQLGKIKTAVTMVAITWLLLGDPLATLIGL
SLGQILLYIGVIFTILSGIEYFYKGRDVFKQK

Sequences:

>Translated_192_residues
MNIPNQITVFRVVLIPVFILFALVDFGFGNVSFLGGYEIRIELLISGFIFILASLSDFVDGYLARKWNLVTNMGKFLDPL
ADKLLVASALIVLVQLGLTNSVVAIIIIAREFAVTGLRLLQIEQGFVSAAGQLGKIKTAVTMVAITWLLLGDPLATLIGL
SLGQILLYIGVIFTILSGIEYFYKGRDVFKQK
>Mature_192_residues
MNIPNQITVFRVVLIPVFILFALVDFGFGNVSFLGGYEIRIELLISGFIFILASLSDFVDGYLARKWNLVTNMGKFLDPL
ADKLLVASALIVLVQLGLTNSVVAIIIIAREFAVTGLRLLQIEQGFVSAAGQLGKIKTAVTMVAITWLLLGDPLATLIGL
SLGQILLYIGVIFTILSGIEYFYKGRDVFKQK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family

Homologues:

Organism=Escherichia coli, GI1788220, Length=195, Percent_Identity=33.8461538461538, Blast_Score=103, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PGSA_STAAC (Q5HGE8)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_186159.1
- STRING:   Q5HGE8
- EnsemblBacteria:   EBSTAT00000008977
- GeneID:   3236361
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL1302
- TIGR:   SACOL1302
- eggNOG:   COG0558
- GeneTree:   EBGT00050000025045
- HOGENOM:   HBG686655
- OMA:   RIALIPF
- ProtClustDB:   CLSK885249
- BioCyc:   SAUR93062:SACOL1302-MONOMER
- InterPro:   IPR000462
- InterPro:   IPR004570
- PIRSF:   PIRSF000847
- TIGRFAMs:   TIGR00560

Pfam domain/function: PF01066 CDP-OH_P_transf

EC number: =2.7.8.5

Molecular weight: Translated: 21015; Mature: 21015

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd91624c)-; HASH(0xd39fd4c)-; HASH(0xe54dc0c)-; HASH(0xd5490a4)-; HASH(0xe660a1c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIPNQITVFRVVLIPVFILFALVDFGFGNVSFLGGYEIRIELLISGFIFILASLSDFVD
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
GYLARKWNLVTNMGKFLDPLADKLLVASALIVLVQLGLTNSVVAIIIIAREFAVTGLRLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
QIEQGFVSAAGQLGKIKTAVTMVAITWLLLGDPLATLIGLSLGQILLYIGVIFTILSGIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFYKGRDVFKQK
HHHCCHHHHCCH
>Mature Secondary Structure
MNIPNQITVFRVVLIPVFILFALVDFGFGNVSFLGGYEIRIELLISGFIFILASLSDFVD
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
GYLARKWNLVTNMGKFLDPLADKLLVASALIVLVQLGLTNSVVAIIIIAREFAVTGLRLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
QIEQGFVSAAGQLGKIKTAVTMVAITWLLLGDPLATLIGLSLGQILLYIGVIFTILSGIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFYKGRDVFKQK
HHHCCHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA