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The map label for this gene is xerC

Identifier: 15926835

GI number: 15926835

Start: 1241147

End: 1242043

Strand: Direct

Name: xerC

Synonym: SA1095

Alternate gene names: 15926835

Gene position: 1241147-1242043 (Clockwise)

Preceding gene: 15926834

Following gene: 15926836

Centisome position: 44.09

GC content: 32.22

Gene sequence:

>897_bases
TTGAATCATATTCAAGAAGCGTTTTTAAATACATTGAAAGTTGAACGGAATTTTTCGGAACATACATTGAAATCATATCA
AGATGACTTAATTCAGTTTAATCAATTTTTAGAACAAGAACATTTACAGTTGAAAACTTTTGAATACAGAGATGCTAGAA
ATTATTTGAGCTATTTATATTCAAATCATTTGAAAAGAACATCTGTTTCTCGTAAAATCTCAACGTTAAGAACTTTCTAT
GAATATTGGATGACGCTTGATGAGAACATTATTAATCCATTTGTTCAATTAGTACATCCGAAAAAAGAAAAATATCTTCC
GCAATTCTTTTACGAAGAAGAAATGGAAGCGTTATTCAAAACTGTAGAAGAGGACACTTCAAAAAATTTACGGGATCGAG
TTATTCTTGAATTGTTGTATGCTACAGGCATCCGTGTTTCGGAATTAGTAAATATTAAAAAACAAGATATAGATTTTTAC
GCGAATGGTGTTACCGTATTAGGAAAAGGGAGCAAAGAGCGTTTTGTACCGTTTGGTGCTTATTGTAGACAAAGCATCGA
AAATTATTTAGAACATTTCAAACCAATTCAGTCATGCAATCATGATTTTCTTATTTTAAATATGAAGGGTGAAGCAATCA
CTGAACGCGGTGTACGATATGTTTTAAATGATATTGTTAAACGAACAGCAGGCGTAAGTGAGATTCATCCCCACAAGCTC
AGACATACATTTGCAACGCATTTATTGAATCAAGGTGCAGACCTAAGAACAGTACAATCGTTATTAGGTCATGTTAATTT
GTCAACAACTGGTAAATATACACACGTATCTAACCAACAATTAAGAAAAGTGTATCTAAATGCACATCCTCGAGCGAAAA
AGGAGAATGAAACATGA

Upstream 100 bases:

>100_bases
TACAATTATTTAATTCTCAAAAGATTTAGAATTGATTATCAAATTACTGTAAGCCCTTTGCTGTATATGCTACAATTCTT
ATTGATGGAGGGTAAATGTA

Downstream 100 bases:

>100_bases
GTAATACAACATTACATGCAACAACAATTTATGCTGTAAGACATAATGGGAAAGCAGCTATGGCTGGAGATGGACAAGTA
ACGCTTGGTCAACAAGTCAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MNHIQEAFLNTLKVERNFSEHTLKSYQDDLIQFNQFLEQEHLQLKTFEYRDARNYLSYLYSNHLKRTSVSRKISTLRTFY
EYWMTLDENIINPFVQLVHPKKEKYLPQFFYEEEMEALFKTVEEDTSKNLRDRVILELLYATGIRVSELVNIKKQDIDFY
ANGVTVLGKGSKERFVPFGAYCRQSIENYLEHFKPIQSCNHDFLILNMKGEAITERGVRYVLNDIVKRTAGVSEIHPHKL
RHTFATHLLNQGADLRTVQSLLGHVNLSTTGKYTHVSNQQLRKVYLNAHPRAKKENET

Sequences:

>Translated_298_residues
MNHIQEAFLNTLKVERNFSEHTLKSYQDDLIQFNQFLEQEHLQLKTFEYRDARNYLSYLYSNHLKRTSVSRKISTLRTFY
EYWMTLDENIINPFVQLVHPKKEKYLPQFFYEEEMEALFKTVEEDTSKNLRDRVILELLYATGIRVSELVNIKKQDIDFY
ANGVTVLGKGSKERFVPFGAYCRQSIENYLEHFKPIQSCNHDFLILNMKGEAITERGVRYVLNDIVKRTAGVSEIHPHKL
RHTFATHLLNQGADLRTVQSLLGHVNLSTTGKYTHVSNQQLRKVYLNAHPRAKKENET
>Mature_298_residues
MNHIQEAFLNTLKVERNFSEHTLKSYQDDLIQFNQFLEQEHLQLKTFEYRDARNYLSYLYSNHLKRTSVSRKISTLRTFY
EYWMTLDENIINPFVQLVHPKKEKYLPQFFYEEEMEALFKTVEEDTSKNLRDRVILELLYATGIRVSELVNIKKQDIDFY
ANGVTVLGKGSKERFVPFGAYCRQSIENYLEHFKPIQSCNHDFLILNMKGEAITERGVRYVLNDIVKRTAGVSEIHPHKL
RHTFATHLLNQGADLRTVQSLLGHVNLSTTGKYTHVSNQQLRKVYLNAHPRAKKENET

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1789261, Length=291, Percent_Identity=38.4879725085911, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1790244, Length=290, Percent_Identity=36.2068965517241, Blast_Score=177, Evalue=6e-46,
Organism=Escherichia coli, GI1790768, Length=171, Percent_Identity=25.1461988304094, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790767, Length=188, Percent_Identity=27.1276595744681, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_STAA1 (A7X1M7)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441832.1
- ProteinModelPortal:   A7X1M7
- SMR:   A7X1M7
- STRING:   A7X1M7
- EnsemblBacteria:   EBSTAT00000005018
- GeneID:   5559296
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1242
- eggNOG:   COG4974
- GeneTree:   EBGT00050000024184
- HOGENOM:   HBG727654
- OMA:   FLDVTYA
- ProtClustDB:   CLSK885232
- BioCyc:   SAUR418127:SAHV_1242-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10
- TIGRFAMs:   TIGR02224

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 35154; Mature: 35154

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: ACT_SITE 145-145 ACT_SITE 169-169 ACT_SITE 238-238 ACT_SITE 241-241 ACT_SITE 264-264 ACT_SITE 273-273

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHIQEAFLNTLKVERNFSEHTLKSYQDDLIQFNQFLEQEHLQLKTFEYRDARNYLSYLY
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNHLKRTSVSRKISTLRTFYEYWMTLDENIINPFVQLVHPKKEKYLPQFFYEEEMEALFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHH
TVEEDTSKNLRDRVILELLYATGIRVSELVNIKKQDIDFYANGVTVLGKGSKERFVPFGA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHH
YCRQSIENYLEHFKPIQSCNHDFLILNMKGEAITERGVRYVLNDIVKRTAGVSEIHPHKL
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
RHTFATHLLNQGADLRTVQSLLGHVNLSTTGKYTHVSNQQLRKVYLNAHPRAKKENET
HHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNHIQEAFLNTLKVERNFSEHTLKSYQDDLIQFNQFLEQEHLQLKTFEYRDARNYLSYLY
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNHLKRTSVSRKISTLRTFYEYWMTLDENIINPFVQLVHPKKEKYLPQFFYEEEMEALFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHH
TVEEDTSKNLRDRVILELLYATGIRVSELVNIKKQDIDFYANGVTVLGKGSKERFVPFGA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHH
YCRQSIENYLEHFKPIQSCNHDFLILNMKGEAITERGVRYVLNDIVKRTAGVSEIHPHKL
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
RHTFATHLLNQGADLRTVQSLLGHVNLSTTGKYTHVSNQQLRKVYLNAHPRAKKENET
HHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA