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The map label for this gene is coaD

Identifier: 15926709

GI number: 15926709

Start: 1101884

End: 1102366

Strand: Direct

Name: coaD

Synonym: SA0973

Alternate gene names: 15926709

Gene position: 1101884-1102366 (Clockwise)

Preceding gene: 15926708

Following gene: 15926711

Centisome position: 39.15

GC content: 30.85

Gene sequence:

>483_bases
ATGGAACATACAATAGCGGTCATTCCGGGTAGTTTTGACCCCATTACTTATGGTCATTTAGACATTATTGAGAGAAGTAC
AGATAGATTTGATGAAATTCATGTCTGTGTTCTTAAAAATAGTAAAAAAGAAGGTACGTTTAGTTTAGAAGAGCGTATGG
ATTTAATTGAACAATCTGTTAAACATTTACCTAATGTCAAGGTTCATCAATTTAGTGGTTTACTAGTCGATTATTGTGAA
CAAGTAGGAGCTAAAACAATCATACGTGGTTTAAGAGCAGTCAGTGATTTTGAATATGAATTACGCTTAACTTCAATGAA
TAAAAAGTTGAACAATGAAATTGAAACGTTATATATGATGTCTAGTACTAATTATTCATTTATAAGTTCAAGTATTGTTA
AAGAAGTTGCAGCTTATCGAGCAGATATTTCTGAATTCGTTCCACCTTATGTTGAAAAGGCATTGAAGAAGAAATTTAAG
TAA

Upstream 100 bases:

>100_bases
TTTAGCAATCATGAAGAAATAGACTATCAACCGTTTAATATGATTAAACGTTACCATTATGGGTTGACAGACACATTGTT
ATTAGAAAAGGGAGAATAGC

Downstream 100 bases:

>100_bases
TAAAAATAACAGTATTTTAGGTTTATCATGGTTTACAATCCTAAAATACTGTTTTCATTTGTTAACGATATTGCTGTATG
ACAGGCGTGTTGAAATCTGT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MEHTIAVIPGSFDPITYGHLDIIERSTDRFDEIHVCVLKNSKKEGTFSLEERMDLIEQSVKHLPNVKVHQFSGLLVDYCE
QVGAKTIIRGLRAVSDFEYELRLTSMNKKLNNEIETLYMMSSTNYSFISSSIVKEVAAYRADISEFVPPYVEKALKKKFK

Sequences:

>Translated_160_residues
MEHTIAVIPGSFDPITYGHLDIIERSTDRFDEIHVCVLKNSKKEGTFSLEERMDLIEQSVKHLPNVKVHQFSGLLVDYCE
QVGAKTIIRGLRAVSDFEYELRLTSMNKKLNNEIETLYMMSSTNYSFISSSIVKEVAAYRADISEFVPPYVEKALKKKFK
>Mature_160_residues
MEHTIAVIPGSFDPITYGHLDIIERSTDRFDEIHVCVLKNSKKEGTFSLEERMDLIEQSVKHLPNVKVHQFSGLLVDYCE
QVGAKTIIRGLRAVSDFEYELRLTSMNKKLNNEIETLYMMSSTNYSFISSSIVKEVAAYRADISEFVPPYVEKALKKKFK

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=154, Percent_Identity=46.1038961038961, Blast_Score=157, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_STAA1 (A7X140)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441706.1
- ProteinModelPortal:   A7X140
- SMR:   A7X140
- STRING:   A7X140
- EnsemblBacteria:   EBSTAT00000004898
- GeneID:   5560640
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1116
- eggNOG:   COG0669
- GeneTree:   EBGT00050000024651
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   SAUR418127:SAHV_1116-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18371; Mature: 18371

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHTIAVIPGSFDPITYGHLDIIERSTDRFDEIHVCVLKNSKKEGTFSLEERMDLIEQSV
CCCEEEEECCCCCCCCCCHHHHHHHCCCCHHHEEEEEEECCCCCCCCCHHHHHHHHHHHH
KHLPNVKVHQFSGLLVDYCEQVGAKTIIRGLRAVSDFEYELRLTSMNKKLNNEIETLYMM
HHCCCCEEHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHHHHHHCCHHHEEEEE
SSTNYSFISSSIVKEVAAYRADISEFVPPYVEKALKKKFK
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MEHTIAVIPGSFDPITYGHLDIIERSTDRFDEIHVCVLKNSKKEGTFSLEERMDLIEQSV
CCCEEEEECCCCCCCCCCHHHHHHHCCCCHHHEEEEEEECCCCCCCCCHHHHHHHHHHHH
KHLPNVKVHQFSGLLVDYCEQVGAKTIIRGLRAVSDFEYELRLTSMNKKLNNEIETLYMM
HHCCCCEEHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHHHHHHCCHHHEEEEE
SSTNYSFISSSIVKEVAAYRADISEFVPPYVEKALKKKFK
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA