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The map label for this gene is pepT

Identifier: 15926420

GI number: 15926420

Start: 796283

End: 797509

Strand: Reverse

Name: pepT

Synonym: SA0698

Alternate gene names: 15926420

Gene position: 797509-796283 (Counterclockwise)

Preceding gene: 15926421

Following gene: 15926416

Centisome position: 28.33

GC content: 35.37

Gene sequence:

>1227_bases
ATGAAGAACCAATTGATAGATAGATTAACAAGATATACGACAATTGATACGCAATCTGATCCAAAATCTACAACAACACC
TTCAACTGAAAAGCAATGGGATTTGTTACATTTATTAGAAAAAGAATTACAACAATTAGGATTGCCAACTGATTTAGATG
AAAATGGCTACTTATTTGCTACATTAGAAAGTAACATCGATGCCGACGTCCCAACAGTTGGATTTTTGGCGCATGTTGAT
ACATCACCTGATTTCAATGCTTCAAATGTTAAACCGCAAATTATTGAAAACTATGATGGTAAGCCATACAAACTAGGCAA
TACTAAACGTGTCTTAGATCCTAAAGTATTTCCAGAACTTAACAGTTTAGTTGGTCATACATTAATGGTAACTGATGGTA
CATCGTTACTAGGTGCAGACGATAAAGCGGGTATTGTGGAAATTATGGAAGCTATTTGTTATTTACAAGAACATCCAGAA
ATTAAACATGGTACCATTCGCATTGGATTTACACCAGACGAAGAAATCGGTCGTGGTCCACATAAATTTGATGTTGACCG
CTTCAATGCTGATTTTGCTTATACTATGGATGGTAGTCAATATGGAGAATTACAATATGAAAGCTTTAACGCTGCTGAAG
CGGTTATTACATGCCACGGTGTAAATGTTCATCCTGGTTCAGCTAAAAATGCAATGGTAAACGCAATACGTTTAGGTGAA
CAATTCGATAGTTTGCTACCTGATAGTGAAGTTCCGGAGCGAACAGAAGGATACGAAGGCTTTTATCACTTAATGAACTT
TGAAGGAACTGTTGAAAAAGCAACTTTGCAATACATTATTCGTGATCATGATAAAAAACAATTCGAATTGCGTAAGAAAC
GTATTTTAGAAATACGTGACGATATCAATGCCCATTTTGAAAATTATCCAGTTAAAGTTGATATATCGGATCAATATTTC
AATATGGCAGAAAAAATATTACCATTGCCTCATATTATTGATATACCTAAACGTGTCTTTGCCAAATTAGATATTCCAGC
AAACACTGAACCTATTCGTGGTGGTACAGATGGTTCACAATTGTCATTTATGGGGTTACCAACTCCAAACATCTTTACAG
GTTGCGGTAACTTCCACGGCCCATATGAATATGCATCCATTGATGTTATGGAAAAAGCAGTACAAGTAATCATTGGAATT
GTAGAAGATATCGCTGAAAATCACTAA

Upstream 100 bases:

>100_bases
TACCTATACACACGTATCAAACAACTGTATGGTAAAATCAAAGGTAAGACATATAAAAAATCTTACAACATGAATAATAG
AGTTTAAGGGGTCGAATATA

Downstream 100 bases:

>100_bases
AAACAAACGATTATATACTAGTTCAACTCAGGCTTAATTAATAAAAAAATCACGCTAACATTCAGTGCAATGATAGCGTG
ATTTTTCATATTTTTTACGT

Product: peptidase T

Products: NA

Alternate protein names: Aminotripeptidase; Tripeptidase; Tripeptide aminopeptidase

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MKNQLIDRLTRYTTIDTQSDPKSTTTPSTEKQWDLLHLLEKELQQLGLPTDLDENGYLFATLESNIDADVPTVGFLAHVD
TSPDFNASNVKPQIIENYDGKPYKLGNTKRVLDPKVFPELNSLVGHTLMVTDGTSLLGADDKAGIVEIMEAICYLQEHPE
IKHGTIRIGFTPDEEIGRGPHKFDVDRFNADFAYTMDGSQYGELQYESFNAAEAVITCHGVNVHPGSAKNAMVNAIRLGE
QFDSLLPDSEVPERTEGYEGFYHLMNFEGTVEKATLQYIIRDHDKKQFELRKKRILEIRDDINAHFENYPVKVDISDQYF
NMAEKILPLPHIIDIPKRVFAKLDIPANTEPIRGGTDGSQLSFMGLPTPNIFTGCGNFHGPYEYASIDVMEKAVQVIIGI
VEDIAENH

Sequences:

>Translated_408_residues
MKNQLIDRLTRYTTIDTQSDPKSTTTPSTEKQWDLLHLLEKELQQLGLPTDLDENGYLFATLESNIDADVPTVGFLAHVD
TSPDFNASNVKPQIIENYDGKPYKLGNTKRVLDPKVFPELNSLVGHTLMVTDGTSLLGADDKAGIVEIMEAICYLQEHPE
IKHGTIRIGFTPDEEIGRGPHKFDVDRFNADFAYTMDGSQYGELQYESFNAAEAVITCHGVNVHPGSAKNAMVNAIRLGE
QFDSLLPDSEVPERTEGYEGFYHLMNFEGTVEKATLQYIIRDHDKKQFELRKKRILEIRDDINAHFENYPVKVDISDQYF
NMAEKILPLPHIIDIPKRVFAKLDIPANTEPIRGGTDGSQLSFMGLPTPNIFTGCGNFHGPYEYASIDVMEKAVQVIIGI
VEDIAENH
>Mature_408_residues
MKNQLIDRLTRYTTIDTQSDPKSTTTPSTEKQWDLLHLLEKELQQLGLPTDLDENGYLFATLESNIDADVPTVGFLAHVD
TSPDFNASNVKPQIIENYDGKPYKLGNTKRVLDPKVFPELNSLVGHTLMVTDGTSLLGADDKAGIVEIMEAICYLQEHPE
IKHGTIRIGFTPDEEIGRGPHKFDVDRFNADFAYTMDGSQYGELQYESFNAAEAVITCHGVNVHPGSAKNAMVNAIRLGE
QFDSLLPDSEVPERTEGYEGFYHLMNFEGTVEKATLQYIIRDHDKKQFELRKKRILEIRDDINAHFENYPVKVDISDQYF
NMAEKILPLPHIIDIPKRVFAKLDIPANTEPIRGGTDGSQLSFMGLPTPNIFTGCGNFHGPYEYASIDVMEKAVQVIIGI
VEDIAENH

Specific function: Cleaves the N-terminal amino acid of tripeptides

COG id: COG2195

COG function: function code E; Di- and tripeptidases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20B family

Homologues:

Organism=Escherichia coli, GI1787372, Length=408, Percent_Identity=51.7156862745098, Blast_Score=431, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PEPT_STAA1 (A7WZN6)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441330.1
- ProteinModelPortal:   A7WZN6
- SMR:   A7WZN6
- STRING:   A7WZN6
- EnsemblBacteria:   EBSTAT00000004734
- GeneID:   5560445
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_0740
- eggNOG:   COG2195
- GeneTree:   EBGT00050000024077
- HOGENOM:   HBG288638
- OMA:   HMDTAPD
- ProtClustDB:   PRK05469
- BioCyc:   SAUR418127:SAHV_0740-MONOMER
- GO:   GO:0005737
- GO:   GO:0006508
- HAMAP:   MF_00550
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650
- InterPro:   IPR010161
- PIRSF:   PIRSF037215
- TIGRFAMs:   TIGR01882

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20; SSF55031 Peptidase_M20_dimer

EC number: =3.4.11.4

Molecular weight: Translated: 45820; Mature: 45820

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00758 ARGE_DAPE_CPG2_1; PS00759 ARGE_DAPE_CPG2_2

Important sites: ACT_SITE 80-80 ACT_SITE 174-174

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNQLIDRLTRYTTIDTQSDPKSTTTPSTEKQWDLLHLLEKELQQLGLPTDLDENGYLFA
CCHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
TLESNIDADVPTVGFLAHVDTSPDFNASNVKPQIIENYDGKPYKLGNTKRVLDPKVFPEL
EECCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHCCCCCCEECCCCCCCCCCHHHHHH
NSLVGHTLMVTDGTSLLGADDKAGIVEIMEAICYLQEHPEIKHGTIRIGFTPDEEIGRGP
HHHHCCEEEEECCCCEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHCCCC
HKFDVDRFNADFAYTMDGSQYGELQYESFNAAEAVITCHGVNVHPGSAKNAMVNAIRLGE
CCCCHHHCCCCEEEEECCCCCCCEEECCCCCCEEEEEEECCEECCCCCHHHHHHHHHHHH
QFDSLLPDSEVPERTEGYEGFYHLMNFEGTVEKATLQYIIRDHDKKQFELRKKRILEIRD
HHHHHCCCCCCCCCCCCCCHHEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
DINAHFENYPVKVDISDQYFNMAEKILPLPHIIDIPKRVFAKLDIPANTEPIRGGTDGSQ
HHHHHHCCCCEEEEECHHHHHHHHHHCCCCHHHHCCHHHHEEECCCCCCCCCCCCCCCCE
LSFMGLPTPNIFTGCGNFHGPYEYASIDVMEKAVQVIIGIVEDIAENH
EEEEECCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNQLIDRLTRYTTIDTQSDPKSTTTPSTEKQWDLLHLLEKELQQLGLPTDLDENGYLFA
CCHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
TLESNIDADVPTVGFLAHVDTSPDFNASNVKPQIIENYDGKPYKLGNTKRVLDPKVFPEL
EECCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHCCCCCCEECCCCCCCCCCHHHHHH
NSLVGHTLMVTDGTSLLGADDKAGIVEIMEAICYLQEHPEIKHGTIRIGFTPDEEIGRGP
HHHHCCEEEEECCCCEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHCCCC
HKFDVDRFNADFAYTMDGSQYGELQYESFNAAEAVITCHGVNVHPGSAKNAMVNAIRLGE
CCCCHHHCCCCEEEEECCCCCCCEEECCCCCCEEEEEEECCEECCCCCHHHHHHHHHHHH
QFDSLLPDSEVPERTEGYEGFYHLMNFEGTVEKATLQYIIRDHDKKQFELRKKRILEIRD
HHHHHCCCCCCCCCCCCCCHHEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
DINAHFENYPVKVDISDQYFNMAEKILPLPHIIDIPKRVFAKLDIPANTEPIRGGTDGSQ
HHHHHHCCCCEEEEECHHHHHHHHHHCCCCHHHHCCHHHHEEECCCCCCCCCCCCCCCCE
LSFMGLPTPNIFTGCGNFHGPYEYASIDVMEKAVQVIIGIVEDIAENH
EEEEECCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA