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The map label for this gene is adh1

Identifier: 15926283

GI number: 15926283

Start: 655557

End: 656567

Strand: Direct

Name: adh1

Synonym: SA0562

Alternate gene names: 15926283

Gene position: 655557-656567 (Clockwise)

Preceding gene: 15926282

Following gene: 15926284

Centisome position: 23.29

GC content: 36.3

Gene sequence:

>1011_bases
ATGAGAGCAGCAGTTGTAACGAAAGATCACAAAGTAAGTATTGAGGACAAAAAGTTAAGAGCTTTAAAACCTGGTGAAGC
ATTGGTACAAACGGAATATTGTGGTGTTTGTCATACCGATTTACATGTTAAGAATGCTGATTTTGGTGATGTTACAGGCG
TTACTTTAGGTCATGAAGGTATTGGTAAAGTCATCGAAGTTGCAGAAGATGTAGAATCATTAAAAATTGGAGACCGTGTG
TCTATCGCTTGGATGTTCGAAAGCTGTGGAAGATGTGAATATTGTACAACAGGTCGTGAAACACTTTGCCGTAGTGTGAA
AAATGCTGGTTATACAGTAGATGGTGCAATGGCTGAACAAGTTATTGTTACTGCAGACTATGCTGTGAAAGTACCTGAAA
AATTAGATCCAGCAGCAGCGTCTTCTATTACATGCGCAGGTGTGACAACTTATAAAGCTGTAAAAGTAAGTAATGTAAAA
CCTGGTCAATGGTTAGGTGTTTTTGGTATAGGTGGTTTAGGTAACCTAGCTTTACAATATGCTAAAAACGTTATGGGGGC
TAAAATTGTTGCCTTCGACATTAATGATGATAAATTAGCATTCGCGAAAGAATTAGGTGCAGATGCTATTATTAATTCTA
AAGATGTTGATCCAGTTGCAGAAGTTATGAAATTAACTGATAACAAAGGATTAGATGCAACAGTGGTAACTTCAGTTGCT
AAGACGCCATTTAACCAAGCGGTTGATGTTGTAAAAGCTGGTGCAAGAGTTGTTGCCGTTGGTTTACCTGTTGATAAAAT
GAACTTAGATATCCCAAGATTAGTGCTTGACGGTATTGAAGTAGTAGGTTCACTTGTTGGTACAAGACAAGACTTACGTG
AAGCGTTTGAATTTGCTGCTGAAAATAAAGTAACACCTAAAGTTCAATTAAGAAAATTAGAAGAAATCAATGATATTTTT
GAAGAAATGGAAAAGGGTACTATAACTGGTAGAATGGTTATTAAATTTTAA

Upstream 100 bases:

>100_bases
TACAAATAAAAATTACATCTATAATTATTCGTTTTCATTTTTGAAAGTAATCGCCAATTAATATCATACATACTGGAGTG
ACTATAAGGAGGACATTATT

Downstream 100 bases:

>100_bases
AAATATCAACTGACTATATAGATAAAGAAGGTAGTGCTCTGAACACTATCATTATAATCAAACACGAGGTTTTCATGAAA
GATAGTGAAAATCTCGTGTT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: ADH [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRV
SIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVK
PGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVA
KTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIF
EEMEKGTITGRMVIKF

Sequences:

>Translated_336_residues
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRV
SIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVK
PGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVA
KTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIF
EEMEKGTITGRMVIKF
>Mature_336_residues
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRV
SIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVK
PGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVA
KTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIF
EEMEKGTITGRMVIKF

Specific function: Preferred Specificity Is Towards 1-Propanol. [C]

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI34577061, Length=368, Percent_Identity=31.25, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI4501933, Length=368, Percent_Identity=30.9782608695652, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4501929, Length=361, Percent_Identity=31.5789473684211, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI71565154, Length=259, Percent_Identity=32.8185328185328, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI71743840, Length=356, Percent_Identity=27.5280898876405, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI262073058, Length=377, Percent_Identity=27.5862068965517, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4501939, Length=363, Percent_Identity=25.8953168044077, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI156523966, Length=363, Percent_Identity=25.8953168044077, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI71565152, Length=363, Percent_Identity=24.2424242424242, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI156627571, Length=265, Percent_Identity=26.0377358490566, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI87081918, Length=336, Percent_Identity=69.0476190476191, Blast_Score=431, Evalue=1e-122,
Organism=Escherichia coli, GI1786518, Length=331, Percent_Identity=30.2114803625378, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI87082401, Length=317, Percent_Identity=29.6529968454259, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1790045, Length=336, Percent_Identity=25, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788073, Length=248, Percent_Identity=29.4354838709677, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI1787863, Length=270, Percent_Identity=29.2592592592593, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1786552, Length=371, Percent_Identity=30.188679245283, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788075, Length=321, Percent_Identity=26.791277258567, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790718, Length=284, Percent_Identity=27.8169014084507, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI226510992, Length=321, Percent_Identity=25.5451713395639, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87082125, Length=351, Percent_Identity=22.2222222222222, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786825, Length=263, Percent_Identity=25.8555133079848, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788407, Length=195, Percent_Identity=28.2051282051282, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71988145, Length=339, Percent_Identity=36.283185840708, Blast_Score=197, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI17562584, Length=342, Percent_Identity=36.5497076023392, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17562582, Length=316, Percent_Identity=38.6075949367089, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17562876, Length=322, Percent_Identity=30.7453416149068, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17562878, Length=218, Percent_Identity=32.5688073394495, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI25146526, Length=248, Percent_Identity=29.0322580645161, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71997431, Length=250, Percent_Identity=29.2, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17565904, Length=214, Percent_Identity=28.9719626168224, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6323961, Length=329, Percent_Identity=38.6018237082067, Blast_Score=217, Evalue=3e-57,
Organism=Saccharomyces cerevisiae, GI6319621, Length=332, Percent_Identity=36.144578313253, Blast_Score=212, Evalue=8e-56,
Organism=Saccharomyces cerevisiae, GI6324486, Length=339, Percent_Identity=36.283185840708, Blast_Score=209, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6323729, Length=329, Percent_Identity=34.3465045592705, Blast_Score=196, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6319949, Length=322, Percent_Identity=28.8819875776398, Blast_Score=120, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6320033, Length=375, Percent_Identity=28.8, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6323980, Length=317, Percent_Identity=26.4984227129338, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6323099, Length=336, Percent_Identity=25.8928571428571, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322619, Length=345, Percent_Identity=26.3768115942029, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319955, Length=345, Percent_Identity=26.0869565217391, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6319258, Length=292, Percent_Identity=26.027397260274, Blast_Score=83, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6319257, Length=328, Percent_Identity=24.6951219512195, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17737895, Length=261, Percent_Identity=30.6513409961686, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI17137530, Length=201, Percent_Identity=27.363184079602, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17737897, Length=250, Percent_Identity=26, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR006140
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 36062; Mature: 36062

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00059 ADH_ZINC ; PS00065 D_2_HYDROXYACID_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEG
CCCEEEECCCEECCCCCHHHCCCCCCHHEEHHHCCEEECCEEECCCCCCCCCEEEECCHH
IGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQ
HHHHHHHHHHHHHHCCCCEEEEEEEEHHCCCCCCCCCCHHHHHHHHHHCCCEECCHHHCE
VIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQY
EEEEECCEEECCCCCCCHHHCCEEEECEEEEEEEEECCCCCCCEEEEEECCCHHHHHHHH
AKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVA
HHHHCCCEEEEEECCCCHHHHHHHCCCCCEECCCCCCHHHHHHHHCCCCCCCHHHHHHHH
KTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAA
HCCHHHHHHHHHCCCEEEEEECCHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ENKVTPKVQLRKLEEINDIFEEMEKGTITGRMVIKF
CCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEC
>Mature Secondary Structure
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEG
CCCEEEECCCEECCCCCHHHCCCCCCHHEEHHHCCEEECCEEECCCCCCCCCEEEECCHH
IGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQ
HHHHHHHHHHHHHHCCCCEEEEEEEEHHCCCCCCCCCCHHHHHHHHHHCCCEECCHHHCE
VIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQY
EEEEECCEEECCCCCCCHHHCCEEEECEEEEEEEEECCCCCCCEEEEEECCCHHHHHHHH
AKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVA
HHHHCCCEEEEEECCCCHHHHHHHCCCCCEECCCCCCHHHHHHHHCCCCCCCHHHHHHHH
KTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAA
HCCHHHHHHHHHCCCEEEEEECCHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ENKVTPKVQLRKLEEINDIFEEMEKGTITGRMVIKF
CCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA