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The map label for this gene is folE2

Identifier: 15926244

GI number: 15926244

Start: 619909

End: 620787

Strand: Reverse

Name: folE2

Synonym: SA0524

Alternate gene names: 15926244

Gene position: 620787-619909 (Counterclockwise)

Preceding gene: 15926245

Following gene: 15926243

Centisome position: 22.05

GC content: 34.81

Gene sequence:

>879_bases
ATGACTGAATTTGATTTATCGACACGAGAAGGTCGTTGGAAACACTTTGGTTCCGTAGATCCTATTGAAGGCACGAAACC
TACTACTAAGAACGAAATGACAGATTTACAAAGTACACATAAAGATTTTTTATTTGAAATAGAAGAAGTTGGTATTAAAA
ACTTAGTGTACCCTGTACTTGTTGACCAGTATCAAACAGCTGGCACATTTAGTTTTTCAACAAGTTTAACAAAAGACGAA
AAAGGTATTAATATGAGCCGTATAATTGAAAGTGTTGAAAAGCACTATGATAATGGTATTGAACTTGAATTTAATACACT
TTATCAGGTGTTACGCACTTTACAAACGAATATGAAACAAAATGCGGCAGGCGTTGATGTTTCTGGGAAATGGTTCTTTG
ACCGCTATAGTCCAACCACAAATATTAAAGCAGTTGGTAATGCCGATGTCACTTATGGATTAGCAATTGACGGTGATAAA
GTTACACGTAAAGAACTTACTATTGAAGCAACTGTCACAACGCTATGCCCTTGTTCAAAAGAAATAAGTGAGTATTCAGC
GCACAACCAACGTGGTGTTGTCACTGTTAAAACATATATTAATAAAGATCAAAACATAGTTGATGACTATAAAAACAAAA
TTTTAGATGCAATGGAAGCTAATGCAAGTTCAATTCTATACCCTATTTTAAAACGTCCTGATGAAAAACGTGTGACAGAG
CGTGCATATGAAAATCCACGTTTTGTCGAAGACTTAATTCGTTTAATTGCCGCGGACTTAGTTGAATTTGATTGGTTAGA
CGGTTTCGATATCGAATGTCGTAATGAAGAGTCTATCCATCAACATGATGCTTTCGCTAAATTAAAGTATCGCAAATAA

Upstream 100 bases:

>100_bases
AAAACAATTAGCAAGTCCTGAAATCGATGGTAAACAACACAGCTTTTTAACAGTCGAACCATATTGGACATATCACTTTA
AATCTTAACGGAGGAAAAAA

Downstream 100 bases:

>100_bases
TATCATATGATTAATTCAAACGCGTAACATTAGTTGCGCGTTTTTATTATACCTTCTAGAGTTGTATATCTCTTTTATAA
ATCTTCTCATTTGATGTGCC

Product: putative GTP cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MTEFDLSTREGRWKHFGSVDPIEGTKPTTKNEMTDLQSTHKDFLFEIEEVGIKNLVYPVLVDQYQTAGTFSFSTSLTKDE
KGINMSRIIESVEKHYDNGIELEFNTLYQVLRTLQTNMKQNAAGVDVSGKWFFDRYSPTTNIKAVGNADVTYGLAIDGDK
VTRKELTIEATVTTLCPCSKEISEYSAHNQRGVVTVKTYINKDQNIVDDYKNKILDAMEANASSILYPILKRPDEKRVTE
RAYENPRFVEDLIRLIAADLVEFDWLDGFDIECRNEESIHQHDAFAKLKYRK

Sequences:

>Translated_292_residues
MTEFDLSTREGRWKHFGSVDPIEGTKPTTKNEMTDLQSTHKDFLFEIEEVGIKNLVYPVLVDQYQTAGTFSFSTSLTKDE
KGINMSRIIESVEKHYDNGIELEFNTLYQVLRTLQTNMKQNAAGVDVSGKWFFDRYSPTTNIKAVGNADVTYGLAIDGDK
VTRKELTIEATVTTLCPCSKEISEYSAHNQRGVVTVKTYINKDQNIVDDYKNKILDAMEANASSILYPILKRPDEKRVTE
RAYENPRFVEDLIRLIAADLVEFDWLDGFDIECRNEESIHQHDAFAKLKYRK
>Mature_291_residues
TEFDLSTREGRWKHFGSVDPIEGTKPTTKNEMTDLQSTHKDFLFEIEEVGIKNLVYPVLVDQYQTAGTFSFSTSLTKDEK
GINMSRIIESVEKHYDNGIELEFNTLYQVLRTLQTNMKQNAAGVDVSGKWFFDRYSPTTNIKAVGNADVTYGLAIDGDKV
TRKELTIEATVTTLCPCSKEISEYSAHNQRGVVTVKTYINKDQNIVDDYKNKILDAMEANASSILYPILKRPDEKRVTER
AYENPRFVEDLIRLIAADLVEFDWLDGFDIECRNEESIHQHDAFAKLKYRK

Specific function: Converts GTP to 7,8-dihydroneopterin triphosphate

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCH4_STAA1 (A7WZ02)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441154.1
- ProteinModelPortal:   A7WZ02
- SMR:   A7WZ02
- STRING:   A7WZ02
- EnsemblBacteria:   EBSTAT00000003365
- GeneID:   5559000
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_0564
- eggNOG:   COG1469
- GeneTree:   EBGT00050000023758
- HOGENOM:   HBG626871
- OMA:   SLMDYEV
- ProtClustDB:   PRK13674
- BioCyc:   SAUR418127:SAHV_0564-MONOMER
- HAMAP:   MF_01527_B
- InterPro:   IPR022838
- InterPro:   IPR003801
- InterPro:   IPR002042
- Gene3D:   G3DSA:3.10.270.10
- TIGRFAMs:   TIGR00294

Pfam domain/function: PF02649 DUF198

EC number: =3.5.4.16

Molecular weight: Translated: 33481; Mature: 33350

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFDLSTREGRWKHFGSVDPIEGTKPTTKNEMTDLQSTHKDFLFEIEEVGIKNLVYPVL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
VDQYQTAGTFSFSTSLTKDEKGINMSRIIESVEKHYDNGIELEFNTLYQVLRTLQTNMKQ
HHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHH
NAAGVDVSGKWFFDRYSPTTNIKAVGNADVTYGLAIDGDKVTRKELTIEATVTTLCPCSK
CCCCCCCCCCEEEECCCCCCCEEEECCCCEEEEEEECCCCCCHHHEEEEEHHHHHCCCHH
EISEYSAHNQRGVVTVKTYINKDQNIVDDYKNKILDAMEANASSILYPILKRPDEKRVTE
HHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHH
RAYENPRFVEDLIRLIAADLVEFDWLDGFDIECRNEESIHQHDAFAKLKYRK
HHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHEECCC
>Mature Secondary Structure 
TEFDLSTREGRWKHFGSVDPIEGTKPTTKNEMTDLQSTHKDFLFEIEEVGIKNLVYPVL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
VDQYQTAGTFSFSTSLTKDEKGINMSRIIESVEKHYDNGIELEFNTLYQVLRTLQTNMKQ
HHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHH
NAAGVDVSGKWFFDRYSPTTNIKAVGNADVTYGLAIDGDKVTRKELTIEATVTTLCPCSK
CCCCCCCCCCEEEECCCCCCCEEEECCCCEEEEEEECCCCCCHHHEEEEEHHHHHCCCHH
EISEYSAHNQRGVVTVKTYINKDQNIVDDYKNKILDAMEANASSILYPILKRPDEKRVTE
HHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHH
RAYENPRFVEDLIRLIAADLVEFDWLDGFDIECRNEESIHQHDAFAKLKYRK
HHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA