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The map label for this gene is rpoB

Identifier: 15926220

GI number: 15926220

Start: 579620

End: 583171

Strand: Direct

Name: rpoB

Synonym: SA0500

Alternate gene names: 15926220

Gene position: 579620-583171 (Clockwise)

Preceding gene: 15926219

Following gene: 15926221

Centisome position: 20.59

GC content: 37.56

Gene sequence:

>3552_bases
TTGGCAGGTCAAGTTGTCCAATATGGAAGACATCGTAAACGTAGAAACTACGCGAGAATTTCAGAAGTATTAGAATTACC
AAACTTAATAGAAATTCAAACTAAATCTTACGAGTGGTTCCTAAGAGAAGGTTTAATCGAAATGTTTAGAGACATTTCTC
CAATTGAAGATTTTACTGGTAATTTGTCATTAGAGTTTGTGGATTACCGTTTAGGAGAACCAAAATATGATTTAGAAGAA
TCTAAAAACCGTGACGCTACTTATGCTGCACCTCTTCGTGTAAAAGTGCGTCTAATCATTAAAGAAACAGGAGAAGTTAA
AGAACAAGAAGTCTTTATGGGTGATTTCCCATTAATGACTGATACAGGTACGTTCGTTATCAATGGTGCAGAACGTGTAA
TCGTATCTCAATTAGTTCGTTCACCATCCGTTTATTTCAATGAAAAAATCGACAAAAATGGTCGTGAAAACTATGATGCA
ACAATTATTCCAAACCGTGGTGCATGGTTAGAATATGAAACAGATGCTAAAGATGTTGTATACGTACGTATTGATAGAAC
ACGTAAACTACCATTAACAGTATTGTTACGTGCATTAGGTTTCTCAAGTGACCAAGAAATTGTTGACCTTTTAGGTGACA
ATGAATATTTACGTAATACTTTAGAGAAAGACGGCACTGAAAACACTGAACAAGCGTTATTAGAAATCTATGAACGTTTA
CGTCCAGGTGAACCACCAACTGTTGAAAATGCTAAAAGTCTATTGTATTCACGTTTCTTTGATCCAAAACGCTATGACTT
AGCAAGCGTGGGTCGTTATAAAACAAACAAAAAATTACATTTAAAACATCGTTTATTTAATCAAAAATTAGCTGAGCCAA
TTGTAAATACTGAAACTGGTGAAATTGTAGTTGAAGAAGGTACAGTGCTTGATCGTCGTAAAATCGACGAAATCATGGAT
GTACTTGAATCAAATGCAAACAGCGAAGTGTTTGAATTGCATGGTAGCGTTATAGACGAGCCAGTAGAAATTCAATCAAT
TAAAGTATATGTTCCTAACGATGATGAAGGTCGTACGACAACTGTAATTGGTAATGCTTTCCCTGACTCAGAAGTTAAAT
GCATTACACCAGCAGATATCATTGCTTCAATGAGTTACTTCTTTAACTTATTAAGCGGTATTGGATATACAGATGATATT
GACCATTTAGGTAACCGTCGTTTACGTTCTGTAGGTGAATTACTACAAAACCAATTCCGTATCGGTTTATCAAGAATGGA
AAGAGTTGTACGTGAAAGAATGTCAATTCAAGATACTGAGTCTATCACACCTCAACAATTAATTAATATTCGACCTGTTA
TTGCATCTATTAAAGAATTCTTTGGTAGCTCTCAATTATCACAATTCATGGACCAAGCAAACCCATTAGCTGAGTTAACG
CATAAACGTCGTCTATCAGCATTAGGACCTGGTGGTTTAACACGTGAACGTGCTCAAATGGAAGTACGTGACGTTCACTA
CTCTCACTATGGCCGTATGTGTCCAATTGAAACACCTGAGGGACCAAACATTGGATTGATTAACTCATTATCAAGTTATG
CACGTGTAAATGAATTCGGCTTTATTGAAACACCATATCGTAAAGTTGATTTAGATACACATGCTATCACTGATCAAATT
GACTATTTAACAGCTGACGAAGAAGATAGCTATGTTGTAGCACAAGCAAACTCTAAATTAGATGAAAATGGTCGTTTCAT
GGATGATGAAGTTGTATGTCGTTTCCGTGGTAACAATACAGTTATGGCTAAAGAAAAAATGGATTATATGGATGTATCGC
CGAAGCAAGTTGTTTCAGCAGCGACAGCATGTATTCCATTCTTAGAAAACGATGACTCAAACCGTGCATTGATGGGTGCG
AACATGCAACGTCAAGCAGTGCCTTTGATGAATCCAGAAGCACCATTTGTTGGAACAGGTATGGAACACGTTGCAGCACG
TGATTCTGGTGCAGCTATTACAGCTAAGCACAGAGGTCGTGTTGAACATGTTGAATCTAATGAAATTCTTGTACGTCGTC
TAGTTGAAGAGAACGGCGTTGAGCATGAAGGTGAATTAGATCGCTATCCATTAGCTAAATTTAAACGTTCAAACTCAGGT
ACATGTTACAACCAACGTCCAATCGTTGCAGTTGGAGATGTTGTTGAGTATAACGAGATTTTAGCAGATGGACCATCTAT
GGAATTAGGAGAAATGGCATTAGGTAGAAACGTAGTAGTTGGTTTCATGACTTGGGACGGTTACAACTATGAGGATGCCG
TTATCATGAGTGAAAGACTTGTGAAAGATGACGTGTATACTTCTATTCATATTGAAGAGTATGAATCAGAAGCACGTGAT
ACTAAGTTAGGACCTGAAGAAATCACAAGAGATATTCCTAATGTTTCTGAAAGTGCACTTAAGAACTTAGACGATCGTGG
TATCGTTTATATTGGTGCAGAAGTAAAAGATGGAGATATTTTAGTTGGTAAAGTAACGCCTAAAGGTGTAACTGAGTTAA
CTGCCGAAGAAAGATTGTTACATGCAATCTTTGGTGAAAAAGCACGTGAAGTTAGAGATACTTCATTACGTGTACCTCAC
GGCGCTGGCGGTATCGTTCTTGATGTAAAAGTATTCAATCGTGAAGAAGGCGACGATACATTATCACCTGGTGTAAACCA
ATTAGTACGTGTATATATCGTTCAAAAACGTAAAATTCATGTTGGTGATAAGATGTGTGGTCGACATGGTAACAAAGGTG
TCATTTCTAAGATTGTTCCTGAAGAAGATATGCCTTACTTACCAGATGGACGTCCGATCGATATCATGTTAAATCCTCTT
GGTGTACCATCTCGTATGAACATCGGACAAGTATTAGAGCTACACTTAGGTATGGCTGCTAAAAATCTTGGTATTCACGT
TGCATCACCAGTATTTGACGGTGCAAACGATGACGATGTATGGTCAACAATTGAAGAAGCTGGTATGGCTCGTGATGGTA
AAACTGTACTTTATGATGGACGTACAGGTGAACCATTCGATAACCGTATTTCAGTAGGTGTAATGTACATGTTGAAACTT
GCGCACATGGTTGATGATAAATTACATGCGCGTTCAACAGGACCATATTCACTTGTTACACAACAACCACTTGGCGGTAA
AGCGCAATTCGGTGGACAACGTTTCGGTGAGATGGAGGTATGGGCACTTGAAGCATATGGTGCTGCATACACATTACAAG
AAATCTTAACTTACAAATCCGATGATACAGTAGGACGTGTGAAAACATACGAGGCTATTGTTAAAGGTGAAAACATCTCT
AGACCAAGTGTTCCAGAATCATTCCGAGTATTGATGAAAGAATTACAAAGTTTAGGTTTAGATGTAAAAGTTATGGATGA
GCAAGATAATGAAATCGAAATGACAGACGTTGATGACGATGATGTTGTAGAACGCAAAGTAGATTTACAACAAAATGATG
CTCCTGAAACACAAAAAGAAGTTACTGATTAA

Upstream 100 bases:

>100_bases
TGTCATCATTAGTGTTGCCGTTTTCTTTTTGTCTTTTTATTAATATGCTTATGGTATTTAGCTAAAAGCGGATCACATAA
TTTTTGAGGGGTGAATCTGT

Downstream 100 bases:

>100_bases
TACGCAATTTACAAAACAGGCAAAAAGATACTAAGCTGAATTTTATTGATGATTCAGTTTAGTACTTTAAGCCATTTTAA
ATAAATGCAAATCAATCAAA

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1183; Mature: 1182

Protein sequence:

>1183_residues
MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE
SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA
TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL
RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD
VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI
DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELT
HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI
DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA
NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG
TCYNQRPIVAVGDVVEYNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD
TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH
GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL
GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL
AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS
RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD

Sequences:

>Translated_1183_residues
MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEE
SKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA
TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL
RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMD
VLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDI
DHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELT
HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQI
DYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGA
NMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG
TCYNQRPIVAVGDVVEYNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARD
TKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPH
GAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL
GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKL
AHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENIS
RPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD
>Mature_1182_residues
AGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEES
KNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDAT
IIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERLR
PGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMDV
LESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDID
HLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELTH
KRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQID
YLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGAN
MQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSGT
CYNQRPIVAVGDVVEYNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARDT
KLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPHG
AGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPLG
VPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKLA
HMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENISR
PSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI4505941, Length=447, Percent_Identity=30.6487695749441, Blast_Score=186, Evalue=2e-46,
Organism=Homo sapiens, GI238908505, Length=448, Percent_Identity=30.5803571428571, Blast_Score=173, Evalue=8e-43,
Organism=Homo sapiens, GI238908503, Length=448, Percent_Identity=30.5803571428571, Blast_Score=173, Evalue=1e-42,
Organism=Homo sapiens, GI33469941, Length=435, Percent_Identity=29.4252873563218, Blast_Score=165, Evalue=2e-40,
Organism=Homo sapiens, GI212286172, Length=435, Percent_Identity=29.4252873563218, Blast_Score=165, Evalue=3e-40,
Organism=Escherichia coli, GI1790419, Length=522, Percent_Identity=60.1532567049808, Blast_Score=661, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=447, Percent_Identity=30.2013422818792, Blast_Score=182, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI25144348, Length=444, Percent_Identity=30.4054054054054, Blast_Score=181, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17506623, Length=221, Percent_Identity=36.1990950226244, Blast_Score=128, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324725, Length=360, Percent_Identity=30.2777777777778, Blast_Score=172, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6324781, Length=437, Percent_Identity=27.9176201372998, Blast_Score=162, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6325267, Length=420, Percent_Identity=29.0476190476191, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI17647877, Length=474, Percent_Identity=29.746835443038, Blast_Score=178, Evalue=2e-44,
Organism=Drosophila melanogaster, GI17136444, Length=424, Percent_Identity=28.5377358490566, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI17136446, Length=437, Percent_Identity=29.0617848970252, Blast_Score=139, Evalue=1e-32,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_STAA1 (A7WYW7)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441130.1
- ProteinModelPortal:   A7WYW7
- SMR:   A7WYW7
- STRING:   A7WYW7
- EnsemblBacteria:   EBSTAT00000005307
- GeneID:   5559150
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_0540
- eggNOG:   COG0085
- GeneTree:   EBGT00050000024500
- HOGENOM:   HBG285547
- OMA:   FMTWEGY
- ProtClustDB:   PRK00405
- BioCyc:   SAUR418127:SAHV_0540-MONOMER
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 133221; Mature: 133090

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHCCC
NLSLEFVDYRLGEPKYDLEESKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMT
CEEEEEEEEECCCCCCCHHHCCCCCCEEECCEEEEEEEEEECCCCCCHHHEEECCCCEEE
DTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDATIIPNRGAWLEYETDAKDVV
CCCCEEECCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEECCCCCEEEEECCCCEEE
YVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL
EEEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETG
CCCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCC
EIVVEEGTVLDRRKIDEIMDVLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTT
CEEEECCCCHHHHHHHHHHHHHHCCCCCCCEECCCHHCCCCEEEEEEEEECCCCCCCCEE
TVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDIDHLGNRRLRSVGELLQNQFR
EEEECCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELT
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHH
HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
FIETPYRKVDLDTHAITDQIDYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNT
CEECCCEEECCCHHHHHHHHHEEECCCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCE
VMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGANMQRQAVPLMNPEAPFVGTG
EEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHCCCCCCCCCCCCCCCC
MEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG
HHHHHCCCCCCEEEECCCCCCEECCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCC
TCYNQRPIVAVGDVVEYNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERL
CEECCCCEEEECCHHHHHHHHCCCCCCCHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHH
VKDDVYTSIHIEEYESEARDTKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDI
HHHHHHEEEEHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHCCCCCCEEEEECEECCCCE
LVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPHGAGGIVLDVKVFNREEGDDT
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEEEEEECCCCCCCC
LSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL
CCHHHHHHHHHHHHHCCEEECCHHHHCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEECCC
GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDG
CCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEECC
RTGEPFDNRISVGVMYMLKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEE
WALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENISRPSVPESFRVLMKELQSLGL
EEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCC
DVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD
CEEEECCCCCEEEEECCCCHHHHHHHHCCCCCCCCCHHHHCCC
>Mature Secondary Structure 
AGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTG
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHCCC
NLSLEFVDYRLGEPKYDLEESKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMT
CEEEEEEEEECCCCCCCHHHCCCCCCEEECCEEEEEEEEEECCCCCCHHHEEECCCCEEE
DTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDATIIPNRGAWLEYETDAKDVV
CCCCEEECCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEECCCCCEEEEECCCCEEE
YVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERL
EEEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
RPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETG
CCCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCC
EIVVEEGTVLDRRKIDEIMDVLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTT
CEEEECCCCHHHHHHHHHHHHHHCCCCCCCEECCCHHCCCCEEEEEEEEECCCCCCCCEE
TVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDIDHLGNRRLRSVGELLQNQFR
EEEECCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELT
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHH
HKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
FIETPYRKVDLDTHAITDQIDYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNT
CEECCCEEECCCHHHHHHHHHEEECCCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCE
VMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGANMQRQAVPLMNPEAPFVGTG
EEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHCCCCCCCCCCCCCCCC
MEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSG
HHHHHCCCCCCEEEECCCCCCEECCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCC
TCYNQRPIVAVGDVVEYNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERL
CEECCCCEEEECCHHHHHHHHCCCCCCCHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHH
VKDDVYTSIHIEEYESEARDTKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDI
HHHHHHEEEEHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHCCCCCCEEEEECEECCCCE
LVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPHGAGGIVLDVKVFNREEGDDT
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEEEEEECCCCCCCC
LSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPL
CCHHHHHHHHHHHHHCCEEECCHHHHCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEECCC
GVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDG
CCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEECC
RTGEPFDNRISVGVMYMLKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEE
WALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENISRPSVPESFRVLMKELQSLGL
EEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCC
DVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD
CEEEECCCCCEEEEECCCCHHHHHHHHCCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA