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The map label for this gene is cysS

Identifier: 15926207

GI number: 15926207

Start: 571154

End: 572554

Strand: Direct

Name: cysS

Synonym: SA0488

Alternate gene names: 15926207

Gene position: 571154-572554 (Clockwise)

Preceding gene: 15926206

Following gene: 15926208

Centisome position: 20.29

GC content: 33.05

Gene sequence:

>1401_bases
ATGATTACATTATATAATACGCTTACACGTCAAAAAGAAGTGTTCAAGCCTATAGAACCAGGGAAAGTAAAAATGTATGT
ATGTGGTCCTACTGTATATAACTACATTCATATTGGTAACGCAAGACCAGCAATTAATTATGACGTAGTGAGACGTTACT
TTGAATACCAAGGATATAATGTAGAATATGTATCAAATTTTACAGACGTAGATGATAAATTAATTAAACGTTCTCAAGAA
TTAAATCAGTCTGTTCCCGAAATTGCAGAAAAATATATCGCTGCTTTTCATGAAGATGTTGGTGCGTTAAATGTTAGAAA
AGCGACTTCAAATCCAAGGGTAATGGACCATATGGATGACATTATTCAATTTATTAAAGATTTGGTGGATCAAGGTTATG
CATATGAAAGTGGTGGCGATGTTTACTTTAGAACACGTAAATTTGAAGGTTATGGTAAATTAAGTCATCAATCCATAGAT
GACTTAAAAGTGGGTGCTCGTATAGATGCAGGAGAGCATAAAGAAGATGCACTTGATTTTACATTGTGGAAAAAAGCGAA
GCCTGGCGAGATTAGTTGGAATAGCCCATTTGGTGAAGGTAGACCAGGATGGCATATAGAATGTTCTGTAATGGCATTTC
ATGAGCTAGGACCTACAATTGATATACATGCGGGTGGTTCAGATTTACAATTTCCACATCATGAAAATGAAATAGCACAA
TCAGAAGCACATAATCATGCGCCATTTGCTAATTATTGGATGCATAATGGTTTCATTAATATTGATAATGAAAAAATGAG
TAAATCACTAGGCAACTTTATTTTAGTTCACGATATTATTAAAGAAGTTGATCCAGATGTACTAAGATTCTTTATGATTA
GCGTACATTATAGAAGCCCAATTAACTATAATCTAGAATTGGTAGAATCAGCACGTAGTGGACTAGAGCGTATTCGCAAT
AGTTATCAATTAATTGAAGAGCGCGCACAAATTGCTACTAATATTGAAAATCAACAGACATATATTGATCAAATTGATGC
GATTTTAAATCGTTTTGAAACAGTTATGAATGATGATTTTAATACAGCTAATGCAATTACAGCTTGGTATGATTTAGCAA
AACTTGCGAATAAATATGTACTAGAGAACACAACATCAACAGAAGTAATTGATAAATTTAAAGCAGTTTATCAAATTTTC
AGCGATGTTTTAGGTGTACCGTTAAAATCTAAAAATGCAGATGAATTATTGGATGAAGATGTTGAAAAATTAATCGAAGA
GCGTAATGAAGCAAGGAAAAACAAAGATTTTGCACGAGCAGATGAGATTCGAGACATGCTGAAATCACAAAACATTATAT
TAGAAGACACACCTCAAGGGGTTAGATTTAAACGTGGATAA

Upstream 100 bases:

>100_bases
GGAAAAACATTTGATCATCGCCATCTACCTGATCCAATTTATGAACAAATTAAGCATTTAGAACGACAACTTGAAAAGAC
TAGGAATGGAGAGATTCAAG

Downstream 100 bases:

>100_bases
TCAACAAGATAATCACATTAAATTATTGAATCCATTGACCTTAGCATATATGGGAGACGCAGTCTTAGATCAATATGTAC
GTACCTATATCGTTTTAAAG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MITLYNTLTRQKEVFKPIEPGKVKMYVCGPTVYNYIHIGNARPAINYDVVRRYFEYQGYNVEYVSNFTDVDDKLIKRSQE
LNQSVPEIAEKYIAAFHEDVGALNVRKATSNPRVMDHMDDIIQFIKDLVDQGYAYESGGDVYFRTRKFEGYGKLSHQSID
DLKVGARIDAGEHKEDALDFTLWKKAKPGEISWNSPFGEGRPGWHIECSVMAFHELGPTIDIHAGGSDLQFPHHENEIAQ
SEAHNHAPFANYWMHNGFINIDNEKMSKSLGNFILVHDIIKEVDPDVLRFFMISVHYRSPINYNLELVESARSGLERIRN
SYQLIEERAQIATNIENQQTYIDQIDAILNRFETVMNDDFNTANAITAWYDLAKLANKYVLENTTSTEVIDKFKAVYQIF
SDVLGVPLKSKNADELLDEDVEKLIEERNEARKNKDFARADEIRDMLKSQNIILEDTPQGVRFKRG

Sequences:

>Translated_466_residues
MITLYNTLTRQKEVFKPIEPGKVKMYVCGPTVYNYIHIGNARPAINYDVVRRYFEYQGYNVEYVSNFTDVDDKLIKRSQE
LNQSVPEIAEKYIAAFHEDVGALNVRKATSNPRVMDHMDDIIQFIKDLVDQGYAYESGGDVYFRTRKFEGYGKLSHQSID
DLKVGARIDAGEHKEDALDFTLWKKAKPGEISWNSPFGEGRPGWHIECSVMAFHELGPTIDIHAGGSDLQFPHHENEIAQ
SEAHNHAPFANYWMHNGFINIDNEKMSKSLGNFILVHDIIKEVDPDVLRFFMISVHYRSPINYNLELVESARSGLERIRN
SYQLIEERAQIATNIENQQTYIDQIDAILNRFETVMNDDFNTANAITAWYDLAKLANKYVLENTTSTEVIDKFKAVYQIF
SDVLGVPLKSKNADELLDEDVEKLIEERNEARKNKDFARADEIRDMLKSQNIILEDTPQGVRFKRG
>Mature_466_residues
MITLYNTLTRQKEVFKPIEPGKVKMYVCGPTVYNYIHIGNARPAINYDVVRRYFEYQGYNVEYVSNFTDVDDKLIKRSQE
LNQSVPEIAEKYIAAFHEDVGALNVRKATSNPRVMDHMDDIIQFIKDLVDQGYAYESGGDVYFRTRKFEGYGKLSHQSID
DLKVGARIDAGEHKEDALDFTLWKKAKPGEISWNSPFGEGRPGWHIECSVMAFHELGPTIDIHAGGSDLQFPHHENEIAQ
SEAHNHAPFANYWMHNGFINIDNEKMSKSLGNFILVHDIIKEVDPDVLRFFMISVHYRSPINYNLELVESARSGLERIRN
SYQLIEERAQIATNIENQQTYIDQIDAILNRFETVMNDDFNTANAITAWYDLAKLANKYVLENTTSTEVIDKFKAVYQIF
SDVLGVPLKSKNADELLDEDVEKLIEERNEARKNKDFARADEIRDMLKSQNIILEDTPQGVRFKRG

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI13375695, Length=482, Percent_Identity=34.4398340248963, Blast_Score=255, Evalue=5e-68,
Organism=Homo sapiens, GI62240992, Length=413, Percent_Identity=33.4140435835351, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI10835051, Length=413, Percent_Identity=33.4140435835351, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI21269877, Length=413, Percent_Identity=33.4140435835351, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI303304987, Length=413, Percent_Identity=33.4140435835351, Blast_Score=192, Evalue=5e-49,
Organism=Escherichia coli, GI1786737, Length=471, Percent_Identity=43.5244161358811, Blast_Score=385, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17509795, Length=327, Percent_Identity=32.7217125382263, Blast_Score=178, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17509797, Length=327, Percent_Identity=32.7217125382263, Blast_Score=178, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6324082, Length=274, Percent_Identity=39.051094890511, Blast_Score=187, Evalue=3e-48,
Organism=Drosophila melanogaster, GI19922218, Length=379, Percent_Identity=38.2585751978892, Blast_Score=239, Evalue=4e-63,
Organism=Drosophila melanogaster, GI19922364, Length=315, Percent_Identity=33.6507936507937, Blast_Score=178, Evalue=9e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYC_STAA1 (A7WYU7)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441117.1
- ProteinModelPortal:   A7WYU7
- SMR:   A7WYU7
- STRING:   A7WYU7
- EnsemblBacteria:   EBSTAT00000003798
- GeneID:   5559522
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_0527
- eggNOG:   COG0215
- GeneTree:   EBGT00050000024049
- HOGENOM:   HBG327651
- OMA:   DFDALNM
- ProtClustDB:   PRK00260
- BioCyc:   SAUR418127:SAHV_0527-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00041_B
- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10890
- PRINTS:   PR00983
- SMART:   SM00840
- TIGRFAMs:   TIGR00435

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.16

Molecular weight: Translated: 53685; Mature: 53685

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 268-268

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLYNTLTRQKEVFKPIEPGKVKMYVCGPTVYNYIHIGNARPAINYDVVRRYFEYQGYN
CEEEHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHCCCC
VEYVSNFTDVDDKLIKRSQELNQSVPEIAEKYIAAFHEDVGALNVRKATSNPRVMDHMDD
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHH
IIQFIKDLVDQGYAYESGGDVYFRTRKFEGYGKLSHQSIDDLKVGARIDAGEHKEDALDF
HHHHHHHHHHCCCEECCCCCEEEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHH
TLWKKAKPGEISWNSPFGEGRPGWHIECSVMAFHELGPTIDIHAGGSDLQFPHHENEIAQ
HHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEHHHCCCEEEEECCCCCCCCCCCHHHHHH
SEAHNHAPFANYWMHNGFINIDNEKMSKSLGNFILVHDIIKEVDPDVLRFFMISVHYRSP
HHCCCCCCHHHHHHCCCEEEECHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHCCCC
INYNLELVESARSGLERIRNSYQLIEERAQIATNIENQQTYIDQIDAILNRFETVMNDDF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
NTANAITAWYDLAKLANKYVLENTTSTEVIDKFKAVYQIFSDVLGVPLKSKNADELLDED
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
VEKLIEERNEARKNKDFARADEIRDMLKSQNIILEDTPQGVRFKRG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MITLYNTLTRQKEVFKPIEPGKVKMYVCGPTVYNYIHIGNARPAINYDVVRRYFEYQGYN
CEEEHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHCCCC
VEYVSNFTDVDDKLIKRSQELNQSVPEIAEKYIAAFHEDVGALNVRKATSNPRVMDHMDD
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHH
IIQFIKDLVDQGYAYESGGDVYFRTRKFEGYGKLSHQSIDDLKVGARIDAGEHKEDALDF
HHHHHHHHHHCCCEECCCCCEEEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHH
TLWKKAKPGEISWNSPFGEGRPGWHIECSVMAFHELGPTIDIHAGGSDLQFPHHENEIAQ
HHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEHHHCCCEEEEECCCCCCCCCCCHHHHHH
SEAHNHAPFANYWMHNGFINIDNEKMSKSLGNFILVHDIIKEVDPDVLRFFMISVHYRSP
HHCCCCCCHHHHHHCCCEEEECHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHCCCC
INYNLELVESARSGLERIRNSYQLIEERAQIATNIENQQTYIDQIDAILNRFETVMNDDF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
NTANAITAWYDLAKLANKYVLENTTSTEVIDKFKAVYQIFSDVLGVPLKSKNADELLDED
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
VEKLIEERNEARKNKDFARADEIRDMLKSQNIILEDTPQGVRFKRG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA