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The map label for this gene is xprT

Identifier: 15926089

GI number: 15926089

Start: 431130

End: 431708

Strand: Direct

Name: xprT

Synonym: SA0373

Alternate gene names: 15926089

Gene position: 431130-431708 (Clockwise)

Preceding gene: 15926085

Following gene: 15926090

Centisome position: 15.32

GC content: 35.75

Gene sequence:

>579_bases
GTGGAGTTACTAGGACAAAAAGTAAAGGAAGACGGCGTTGTCATTGATGAGAAGATTTTAAAAGTCGATGGATTTTTAAA
TCATCAAATTGATGCAAAGTTAATGAATGAAGTTGGTCGCACTTTTTACGAGCAATTTAAAGATAAAGGGATTACTAAAA
TCTTAACCATTGAAGCTTCCGGTATCGCACCTGCAATCATGGCTGCACTGCATTTTGATGTGCCATGTTTATTTGCGAAA
AAAGCAAAACCTAGCACTTTGACGGATGGTTATTATGAAACATCTATTCATTCATTTACTAAAAATAAAACAAGTACGGT
CATTGTTTCAAAAGAATTTTTATCAGAAGAAGATACTGTACTCATCATCGATGACTTTTTAGCAAATGGTGATGCTTCAT
TAGGATTATACGATATCGCACAGCAAGCGAATGCTAAGACAGCTGGTATTGGTATTGTTGTTGAAAAGAGTTTCCAAAAT
GGGCATCAACGTTTAGAAGAAGCAGGTTTAACAGTTTCTTCTCTCTGCAAGGTTGCTTCACTAGAAGGAAACAAAGTGAC
ATTGGTGGGAGAAGAATAA

Upstream 100 bases:

>100_bases
CTCATAAACCCTGAAACTATTATTTAGTTTGGGGATTTTTTTGTATCTAGCACCAATTTAAGAGCAAAATGTTTCACACA
AATCTGAGGAGGTTTTAAGA

Downstream 100 bases:

>100_bases
TGAAAAATTTAATCCTAAGTGTTCAACATCTTTTAGCTATGTACGCAGGTGCCATCTTAGTTCCAATCATTGTTGGTACA
AGTTTGAAGTTTACACCTGA

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAK
KAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQN
GHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE

Sequences:

>Translated_192_residues
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAK
KAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQN
GHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
>Mature_192_residues
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAK
KAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQN
GHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XPT_STAA1 (A7WY89)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001440975.1
- ProteinModelPortal:   A7WY89
- SMR:   A7WY89
- STRING:   A7WY89
- EnsemblBacteria:   EBSTAT00000003193
- GeneID:   5559318
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_0385
- eggNOG:   COG0503
- GeneTree:   EBGT00050000024618
- HOGENOM:   HBG288993
- OMA:   ATVYSFT
- ProtClustDB:   PRK09219
- BioCyc:   SAUR418127:SAHV_0385-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01184
- InterPro:   IPR000836
- InterPro:   IPR010079
- TIGRFAMs:   TIGR01744

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 20884; Mature: 20884

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 20-20 BINDING 27-27 BINDING 156-156

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEAS
CCCHHHHHHHCCEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTV
CCHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEHHHCCCCCCE
LIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVAS
EEEECCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHCCCHHHHHHHHC
LEGNKVTLVGEE
CCCCEEEEEECC
>Mature Secondary Structure
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEAS
CCCHHHHHHHCCEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTV
CCHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEHHHCCCCCCE
LIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVAS
EEEECCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHCCCHHHHHHHHC
LEGNKVTLVGEE
CCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA