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The map label for this gene is ykuT [H]

Identifier: 15926062

GI number: 15926062

Start: 409131

End: 410012

Strand: Direct

Name: ykuT [H]

Synonym: SA0349

Alternate gene names: 15926062

Gene position: 409131-410012 (Clockwise)

Preceding gene: 15926061

Following gene: 15926063

Centisome position: 14.53

GC content: 31.41

Gene sequence:

>882_bases
ATGGATCAAGTTATGAGTATTATTTCATCGCTATTCGAACCATTAACTAAAATTGAAACATATGAAAATATTGCAACTAA
AATCGCTATGATTGTTATTTATATTATCGTAGCCCTCATAGTTATTAAAATACTGAATAAAATGATTGAACAGGGATTTA
AGATTCAAAATAAAAGTAAAAAGAGTAACAAAAAGCGCTCTAAAACTTTAATATCTCTTGTTCAAAATGTAGTGAAGTAT
ATCGTTTGGTTTATAGTTATTACGACGATTTTAAGTAAATTTGGCATTAGTGTTGAAGGTGTTATTGCAAGTGCTGGTGT
CGTAGGTTTAGCAGTAGGTTTTGGTGCGCAGACCATTGTTAAAGACGTTATTACTGGATTTTTCATTATATTTGAAAGCC
AATTTGATGTAGGTGATTATGTTAAGATAAACAACGGTGGTACAACTGTAGCAGAGGGAACAGTTAAATCAATTGGACTC
CGTTCAACACGTATTAATACAATATCTGGAGAACTTACAATCTTGCCAAATAGTAGCATGGGTGAAATAACGAATTACTC
AATTACGAATGGAACAGCAATTGTTAAAATTCCAGTATCTGTAGATGAAAATATTGATAATGTTGAGAAGAAATTAAACA
AATTATTTACATCTCTGCGTAGTAAATATTATTTATTTGTAAGTGATCCTGTTGTGATTGGTATTGATGCCTTTGAAGAT
ACTAGAGTAATATTAAGGGTTTCAGCAGAAACAATACCAGGTGAAGGTTTCTCTGGTGCGCGTATTATTCGTAAAGAAGT
ACAAAAAATGTTTTTACAAGAAGGTATCAAGACACCACAACCAATAATGACACCTTTTAATCATAGTGAAAACGGTGTTT
AG

Upstream 100 bases:

>100_bases
ATCTATATTCTTTGAAGATGATGCGACTTCAGTAGGTTGGAAGAATACAACAATATTAATAAAATTATTTGAGACTATAT
AGAAGGGAGTAACGCTAATT

Downstream 100 bases:

>100_bases
TAGTTTATAATACATGGAGGTCATATTTAATGGCGTCAAAATATGGAATAAATGATATAGTAGAAATGAAAAAACAACAT
GCGTGTGGAACCAATCGTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MDQVMSIISSLFEPLTKIETYENIATKIAMIVIYIIVALIVIKILNKMIEQGFKIQNKSKKSNKKRSKTLISLVQNVVKY
IVWFIVITTILSKFGISVEGVIASAGVVGLAVGFGAQTIVKDVITGFFIIFESQFDVGDYVKINNGGTTVAEGTVKSIGL
RSTRINTISGELTILPNSSMGEITNYSITNGTAIVKIPVSVDENIDNVEKKLNKLFTSLRSKYYLFVSDPVVIGIDAFED
TRVILRVSAETIPGEGFSGARIIRKEVQKMFLQEGIKTPQPIMTPFNHSENGV

Sequences:

>Translated_293_residues
MDQVMSIISSLFEPLTKIETYENIATKIAMIVIYIIVALIVIKILNKMIEQGFKIQNKSKKSNKKRSKTLISLVQNVVKY
IVWFIVITTILSKFGISVEGVIASAGVVGLAVGFGAQTIVKDVITGFFIIFESQFDVGDYVKINNGGTTVAEGTVKSIGL
RSTRINTISGELTILPNSSMGEITNYSITNGTAIVKIPVSVDENIDNVEKKLNKLFTSLRSKYYLFVSDPVVIGIDAFED
TRVILRVSAETIPGEGFSGARIIRKEVQKMFLQEGIKTPQPIMTPFNHSENGV
>Mature_293_residues
MDQVMSIISSLFEPLTKIETYENIATKIAMIVIYIIVALIVIKILNKMIEQGFKIQNKSKKSNKKRSKTLISLVQNVVKY
IVWFIVITTILSKFGISVEGVIASAGVVGLAVGFGAQTIVKDVITGFFIIFESQFDVGDYVKINNGGTTVAEGTVKSIGL
RSTRINTISGELTILPNSSMGEITNYSITNGTAIVKIPVSVDENIDNVEKKLNKLFTSLRSKYYLFVSDPVVIGIDAFED
TRVILRVSAETIPGEGFSGARIIRKEVQKMFLQEGIKTPQPIMTPFNHSENGV

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=260, Percent_Identity=29.6153846153846, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787591, Length=169, Percent_Identity=26.0355029585799, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789291, Length=201, Percent_Identity=26.3681592039801, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786670, Length=148, Percent_Identity=26.3513513513513, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 32207; Mature: 32207

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQVMSIISSLFEPLTKIETYENIATKIAMIVIYIIVALIVIKILNKMIEQGFKIQNKSK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
KSNKKRSKTLISLVQNVVKYIVWFIVITTILSKFGISVEGVIASAGVVGLAVGFGAQTIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHCCHHHHH
KDVITGFFIIFESQFDVGDYVKINNGGTTVAEGTVKSIGLRSTRINTISGELTILPNSSM
HHHHHHHHEEEECCCCCCCEEEECCCCCEEECCHHHHCCCCCCEEEEECCEEEEECCCCC
GEITNYSITNGTAIVKIPVSVDENIDNVEKKLNKLFTSLRSKYYLFVSDPVVIGIDAFED
CCCCCEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEECCCC
TRVILRVSAETIPGEGFSGARIIRKEVQKMFLQEGIKTPQPIMTPFNHSENGV
CEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDQVMSIISSLFEPLTKIETYENIATKIAMIVIYIIVALIVIKILNKMIEQGFKIQNKSK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
KSNKKRSKTLISLVQNVVKYIVWFIVITTILSKFGISVEGVIASAGVVGLAVGFGAQTIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHCCHHHHH
KDVITGFFIIFESQFDVGDYVKINNGGTTVAEGTVKSIGLRSTRINTISGELTILPNSSM
HHHHHHHHEEEECCCCCCCEEEECCCCCEEECCHHHHCCCCCCEEEEECCEEEEECCCCC
GEITNYSITNGTAIVKIPVSVDENIDNVEKKLNKLFTSLRSKYYLFVSDPVVIGIDAFED
CCCCCEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEECCCC
TRVILRVSAETIPGEGFSGARIIRKEVQKMFLQEGIKTPQPIMTPFNHSENGV
CEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]