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The map label for this gene is yqeF [C]

Identifier: 15926055

GI number: 15926055

Start: 399116

End: 400297

Strand: Direct

Name: yqeF [C]

Synonym: SA0342

Alternate gene names: 15926055

Gene position: 399116-400297 (Clockwise)

Preceding gene: 15926053

Following gene: 15926061

Centisome position: 14.18

GC content: 38.49

Gene sequence:

>1182_bases
ATGACGAGAGTCGTATTAGCAGCAGCATACAGGACACCTATTGGCGTTTTTGGAGGTGCGTTTAAAGACGTGCCAGCCTA
TGATTTAGGTGCGACTTTAATAGAACATATTATTAAAGAGACGGGTTTGAATCCAAGTGAGATTGATGAAGTTATCATCG
GTAACGTACTACAAGCAGGACAAGGACAAAATCCAGCACGAATTGCTGCTATGAAAGGTGGCTTGCCAGAAACAGTACCT
GCATTTACAGTGAATAAAGTATGTGGTTCTGGGTTAAAGTCGATTCAATTAGCATATCAATCTATTGTGACTGGTGAAAA
TGACATCGTGCTAGCTGGCGGTATGGAGAATATGTCTCAGTCACCAATGCTTGTCAACAACAGTCGCTTCGGTTTTAAAA
TGGGACATCAATCAATGGTTGATAGCATGGTATATGATGGTTTAACAGATGTATTTAATCAATATCATATGGGTATTACT
GCTGAAAATTTAGTAGAGCAATATGGTATTTCAAGAGAAGAACAAGATACATTTGCTGTAAACTCACAACATAAAGCAGT
ACGTGCACAGCAAAATGGTGAATTTGATAGTGAAATAGTTCCAGTATCGATTCCTCAACGTAAAGGTGAACCAATCTTAG
TCACTAAGGATGAAGGTGTACGTGAAAATGTATCAGTCGAAAAATTAAGTCGCTTAAGACCAGCTTTCAAAAAAGACGGG
ACAGTTACAGCAGGTAATGCATCAGGAATCAATGATGGTGCTGCGATGATGTTAGTCATGTCAGAAGACAAAGCTAAAGA
ATTAAATATCGAACCATTGGCAGTGCTTGATGGCTTTGGAAGTCATGGCGTAGATCCTTCTATTATGGGTATTGCACCAG
TTGGCGCTGTAGAAAAGGCTTTGAAACGTAGTAAAAAAGAATTAAGCGATATTGATGTATTTGAATTAAATGAAGCATTT
GCAGCACAATTATTAGCTGTTGATCGTGAATTAAAATTACCTCCTGAAAAGGTGAATGTTAAAGGTGGCGCTATTGCATT
AGGACACCCTATTGGTGCATCTGGTGCTAGAGTTTTAGTGACATTATTGCATCAACTGAATGATGAAGTTGAAACTGGTT
TAACATCATTGTGTATTGGTGGCGGTCAAGCTATCGCTGCAGTTGTATCAAAGTATAAATAA

Upstream 100 bases:

>100_bases
TACGTAGCAATTGGTTTCATAAATTGGATGTTAGTGGCGTATTGGTTCATTAGACGTATTAGTAATAAAATTGTATATAT
CATAAGGAGATGAATATGAC

Downstream 100 bases:

>100_bases
TAAGAAAACAGGTTATCACAACAGTATTAATTACATGTTGGCATAACCTGTTTTTATTTGTTTATGGATTTATTGGGTAA
TATTAGTCATTTGATGGTTT

Product: hypothetical protein

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MTRVVLAAAYRTPIGVFGGAFKDVPAYDLGATLIEHIIKETGLNPSEIDEVIIGNVLQAGQGQNPARIAAMKGGLPETVP
AFTVNKVCGSGLKSIQLAYQSIVTGENDIVLAGGMENMSQSPMLVNNSRFGFKMGHQSMVDSMVYDGLTDVFNQYHMGIT
AENLVEQYGISREEQDTFAVNSQHKAVRAQQNGEFDSEIVPVSIPQRKGEPILVTKDEGVRENVSVEKLSRLRPAFKKDG
TVTAGNASGINDGAAMMLVMSEDKAKELNIEPLAVLDGFGSHGVDPSIMGIAPVGAVEKALKRSKKELSDIDVFELNEAF
AAQLLAVDRELKLPPEKVNVKGGAIALGHPIGASGARVLVTLLHQLNDEVETGLTSLCIGGGQAIAAVVSKYK

Sequences:

>Translated_393_residues
MTRVVLAAAYRTPIGVFGGAFKDVPAYDLGATLIEHIIKETGLNPSEIDEVIIGNVLQAGQGQNPARIAAMKGGLPETVP
AFTVNKVCGSGLKSIQLAYQSIVTGENDIVLAGGMENMSQSPMLVNNSRFGFKMGHQSMVDSMVYDGLTDVFNQYHMGIT
AENLVEQYGISREEQDTFAVNSQHKAVRAQQNGEFDSEIVPVSIPQRKGEPILVTKDEGVRENVSVEKLSRLRPAFKKDG
TVTAGNASGINDGAAMMLVMSEDKAKELNIEPLAVLDGFGSHGVDPSIMGIAPVGAVEKALKRSKKELSDIDVFELNEAF
AAQLLAVDRELKLPPEKVNVKGGAIALGHPIGASGARVLVTLLHQLNDEVETGLTSLCIGGGQAIAAVVSKYK
>Mature_392_residues
TRVVLAAAYRTPIGVFGGAFKDVPAYDLGATLIEHIIKETGLNPSEIDEVIIGNVLQAGQGQNPARIAAMKGGLPETVPA
FTVNKVCGSGLKSIQLAYQSIVTGENDIVLAGGMENMSQSPMLVNNSRFGFKMGHQSMVDSMVYDGLTDVFNQYHMGITA
ENLVEQYGISREEQDTFAVNSQHKAVRAQQNGEFDSEIVPVSIPQRKGEPILVTKDEGVRENVSVEKLSRLRPAFKKDGT
VTAGNASGINDGAAMMLVMSEDKAKELNIEPLAVLDGFGSHGVDPSIMGIAPVGAVEKALKRSKKELSDIDVFELNEAFA
AQLLAVDRELKLPPEKVNVKGGAIALGHPIGASGARVLVTLLHQLNDEVETGLTSLCIGGGQAIAAVVSKYK

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI148539872, Length=391, Percent_Identity=50.1278772378517, Blast_Score=379, Evalue=1e-105,
Organism=Homo sapiens, GI167614485, Length=388, Percent_Identity=44.5876288659794, Blast_Score=327, Evalue=1e-89,
Organism=Homo sapiens, GI4557237, Length=392, Percent_Identity=43.6224489795918, Blast_Score=319, Evalue=2e-87,
Organism=Homo sapiens, GI4501853, Length=392, Percent_Identity=44.1326530612245, Blast_Score=297, Evalue=1e-80,
Organism=Homo sapiens, GI4504327, Length=427, Percent_Identity=33.4894613583138, Blast_Score=208, Evalue=6e-54,
Organism=Homo sapiens, GI194353979, Length=393, Percent_Identity=34.6055979643766, Blast_Score=189, Evalue=4e-48,
Organism=Escherichia coli, GI87082165, Length=392, Percent_Identity=52.2959183673469, Blast_Score=412, Evalue=1e-116,
Organism=Escherichia coli, GI1788554, Length=393, Percent_Identity=52.9262086513995, Blast_Score=387, Evalue=1e-109,
Organism=Escherichia coli, GI1787663, Length=401, Percent_Identity=40.3990024937656, Blast_Score=285, Evalue=3e-78,
Organism=Escherichia coli, GI48994986, Length=401, Percent_Identity=42.643391521197, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI1788683, Length=400, Percent_Identity=30.25, Blast_Score=182, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI133906874, Length=390, Percent_Identity=45.6410256410256, Blast_Score=332, Evalue=3e-91,
Organism=Caenorhabditis elegans, GI25147385, Length=386, Percent_Identity=41.1917098445596, Blast_Score=290, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI17535921, Length=391, Percent_Identity=41.4322250639386, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI17551802, Length=429, Percent_Identity=33.3333333333333, Blast_Score=207, Evalue=8e-54,
Organism=Caenorhabditis elegans, GI17535917, Length=392, Percent_Identity=31.1224489795918, Blast_Score=175, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6325229, Length=394, Percent_Identity=45.1776649746193, Blast_Score=305, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6322031, Length=394, Percent_Identity=39.5939086294416, Blast_Score=246, Evalue=6e-66,
Organism=Drosophila melanogaster, GI24655093, Length=392, Percent_Identity=51.530612244898, Blast_Score=396, Evalue=1e-110,
Organism=Drosophila melanogaster, GI17648125, Length=389, Percent_Identity=44.2159383033419, Blast_Score=314, Evalue=7e-86,
Organism=Drosophila melanogaster, GI24640423, Length=392, Percent_Identity=42.6020408163265, Blast_Score=304, Evalue=6e-83,
Organism=Drosophila melanogaster, GI17137578, Length=425, Percent_Identity=30.5882352941176, Blast_Score=184, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 41753; Mature: 41622

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00098 THIOLASE_1 ; PS00737 THIOLASE_2 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVVLAAAYRTPIGVFGGAFKDVPAYDLGATLIEHIIKETGLNPSEIDEVIIGNVLQAG
CCEEEEEEHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
QGQNPARIAAMKGGLPETVPAFTVNKVCGSGLKSIQLAYQSIVTGENDIVLAGGMENMSQ
CCCCCCEEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECCCCCCCC
SPMLVNNSRFGFKMGHQSMVDSMVYDGLTDVFNQYHMGITAENLVEQYGISREEQDTFAV
CCEEEECCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEE
NSQHKAVRAQQNGEFDSEIVPVSIPQRKGEPILVTKDEGVRENVSVEKLSRLRPAFKKDG
CCHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHCHHHHCCC
TVTAGNASGINDGAAMMLVMSEDKAKELNIEPLAVLDGFGSHGVDPSIMGIAPVGAVEKA
CEEECCCCCCCCCEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCEEECCHHHHHHH
LKRSKKELSDIDVFELNEAFAAQLLAVDRELKLPPEKVNVKGGAIALGHPIGASGARVLV
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCEEEECCCCCCCHHHHHH
TLLHQLNDEVETGLTSLCIGGGQAIAAVVSKYK
HHHHHHCHHHHHCHHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure 
TRVVLAAAYRTPIGVFGGAFKDVPAYDLGATLIEHIIKETGLNPSEIDEVIIGNVLQAG
CEEEEEEHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
QGQNPARIAAMKGGLPETVPAFTVNKVCGSGLKSIQLAYQSIVTGENDIVLAGGMENMSQ
CCCCCCEEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECCCCCCCC
SPMLVNNSRFGFKMGHQSMVDSMVYDGLTDVFNQYHMGITAENLVEQYGISREEQDTFAV
CCEEEECCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEE
NSQHKAVRAQQNGEFDSEIVPVSIPQRKGEPILVTKDEGVRENVSVEKLSRLRPAFKKDG
CCHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHCHHHHCCC
TVTAGNASGINDGAAMMLVMSEDKAKELNIEPLAVLDGFGSHGVDPSIMGIAPVGAVEKA
CEEECCCCCCCCCEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCEEECCHHHHHHH
LKRSKKELSDIDVFELNEAFAAQLLAVDRELKLPPEKVNVKGGAIALGHPIGASGARVLV
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCEEEECCCCCCCHHHHHH
TLLHQLNDEVETGLTSLCIGGGQAIAAVVSKYK
HHHHHHCHHHHHCHHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA