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The map label for this gene is plc

Identifier: 15925799

GI number: 15925799

Start: 102646

End: 103632

Strand: Direct

Name: plc

Synonym: SA0091

Alternate gene names: 15925799

Gene position: 102646-103632 (Clockwise)

Preceding gene: 15925798

Following gene: 15925800

Centisome position: 3.65

GC content: 33.74

Gene sequence:

>987_bases
ATGAAAAAGTGTATTAAGACTTTGTTTTTAAGTATCATTTTAGTAGTGATGGGTGGTTGGTATCATTCAGCACATGCGTC
AGATTCGTTGAGTAAAAGTCCAGAAAATTGGATGAGTAAACTTGATGAAAGCAAACATTTAACTGAGATTAATATGCCAG
GCTCACATGATAGTGGCTCATTCACTTTAACTGATCCGGTAAAATCGGTTTGGGCAAAGACTCAAGGCAAAGATTACCTT
ACTCAAATGAAGTCGGGAGTCAGGTTTTTTGATATTAGAGGTAGAGCAAGTGCTGATAATATGATTTCAGTTCATCACGG
CATGGTTTATTTGCATCATGAACTAGGAAAATTTTTAGATGATGCTAAATATTACTTGAGTGCTTATCCAAACGAAACAA
TTGTGATGTCTATGAAAAAGGACTACGATAGCGATTCTAAAGTTACGAAGACATTTGAAGAGATTTTTAGAGAATATTAT
TATAATAACCCGCAATATCAGAATCTTTTTTACACAGGAAGTAATGCGAATCCTACTTTAAAAGAAACGAAAGGTAAAAT
TGTCCTATTCAATAGAATGGGGGGTACATACATAAAGAGTGGTTATGGTGCTGACACGTCAGGTATTCAATGGGCAGACA
ATGCGACATTTGAAACGAAAATTAATAATGGTAGCTTAAATTTAAAAGTACAAGATGAGTATAAAGATTACTATGATAAA
AAAGTTGAAGCTGTTAAAAATTTATTGGCTAAAGCTAAAACGGATAGTAACAAAGACAATGTATATGTGAATTTCTTGAG
TGTAGCGTCTGGAGGTAGCGCATTTAATAGTACTTATAACTATGCATCACATATAAATCCTGAAATTGCAAAAACGATTA
AAGAAAACGGGAAAGCTAGAACTGGTTGGCTGATTGTTGACTATGCAGGATATCCGTGGCCTGGATATGATGATATCGTA
AGTGAAATTATAGATAGTAATAAATAA

Upstream 100 bases:

>100_bases
ACTCTTAAATATTGTTTAAATAAGTTTTAAAATTTTACACATATTTTTATTTAAAAAAGATGTATAATTAATGTATTAAA
TATAGAAAGAAGTTGATATT

Downstream 100 bases:

>100_bases
GGATTCAATAATGATATTAAGACGAGTATGAAAATAGTTAGATTCTAATTATTTTCACTACTCGTTTTTATTTTGAAAAT
AAGTAATAATTCAACAATAT

Product: 1-phosphatidylinositol phosphodiesterase precurosr

Products: NA

Alternate protein names: Phosphatidylinositol diacylglycerol-lyase; Phosphatidylinositol-specific phospholipase C; PI-PLC [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MKKCIKTLFLSIILVVMGGWYHSAHASDSLSKSPENWMSKLDESKHLTEINMPGSHDSGSFTLTDPVKSVWAKTQGKDYL
TQMKSGVRFFDIRGRASADNMISVHHGMVYLHHELGKFLDDAKYYLSAYPNETIVMSMKKDYDSDSKVTKTFEEIFREYY
YNNPQYQNLFYTGSNANPTLKETKGKIVLFNRMGGTYIKSGYGADTSGIQWADNATFETKINNGSLNLKVQDEYKDYYDK
KVEAVKNLLAKAKTDSNKDNVYVNFLSVASGGSAFNSTYNYASHINPEIAKTIKENGKARTGWLIVDYAGYPWPGYDDIV
SEIIDSNK

Sequences:

>Translated_328_residues
MKKCIKTLFLSIILVVMGGWYHSAHASDSLSKSPENWMSKLDESKHLTEINMPGSHDSGSFTLTDPVKSVWAKTQGKDYL
TQMKSGVRFFDIRGRASADNMISVHHGMVYLHHELGKFLDDAKYYLSAYPNETIVMSMKKDYDSDSKVTKTFEEIFREYY
YNNPQYQNLFYTGSNANPTLKETKGKIVLFNRMGGTYIKSGYGADTSGIQWADNATFETKINNGSLNLKVQDEYKDYYDK
KVEAVKNLLAKAKTDSNKDNVYVNFLSVASGGSAFNSTYNYASHINPEIAKTIKENGKARTGWLIVDYAGYPWPGYDDIV
SEIIDSNK
>Mature_328_residues
MKKCIKTLFLSIILVVMGGWYHSAHASDSLSKSPENWMSKLDESKHLTEINMPGSHDSGSFTLTDPVKSVWAKTQGKDYL
TQMKSGVRFFDIRGRASADNMISVHHGMVYLHHELGKFLDDAKYYLSAYPNETIVMSMKKDYDSDSKVTKTFEEIFREYY
YNNPQYQNLFYTGSNANPTLKETKGKIVLFNRMGGTYIKSGYGADTSGIQWADNATFETKINNGSLNLKVQDEYKDYYDK
KVEAVKNLLAKAKTDSNKDNVYVNFLSVASGGSAFNSTYNYASHINPEIAKTIKENGKARTGWLIVDYAGYPWPGYDDIV
SEIIDSNK

Specific function: Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates. Potential virulence factor [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PI-PLC X-box domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017946
- InterPro:   IPR000909 [H]

Pfam domain/function: PF00388 PI-PLC-X [H]

EC number: =4.6.1.13 [H]

Molecular weight: Translated: 37088; Mature: 37088

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS50007 PIPLC_X_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKCIKTLFLSIILVVMGGWYHSAHASDSLSKSPENWMSKLDESKHLTEINMPGSHDSGS
CHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCHHHHHHHHCCCCCEEEECCCCCCCCCC
FTLTDPVKSVWAKTQGKDYLTQMKSGVRFFDIRGRASADNMISVHHGMVYLHHELGKFLD
EEECHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCCCCCEEEECCCEEEEHHHHHHHHH
DAKYYLSAYPNETIVMSMKKDYDSDSKVTKTFEEIFREYYYNNPQYQNLFYTGSNANPTL
HHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCH
KETKGKIVLFNRMGGTYIKSGYGADTSGIQWADNATFETKINNGSLNLKVQDEYKDYYDK
HHCCCCEEEEECCCCCEEECCCCCCCCCCEECCCCEEEEEECCCEEEEEECHHHHHHHHH
KVEAVKNLLAKAKTDSNKDNVYVNFLSVASGGSAFNSTYNYASHINPEIAKTIKENGKAR
HHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCHHCCCCCHHHHCCHHHHHHHHHCCCCE
TGWLIVDYAGYPWPGYDDIVSEIIDSNK
ECEEEEECCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKKCIKTLFLSIILVVMGGWYHSAHASDSLSKSPENWMSKLDESKHLTEINMPGSHDSGS
CHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCHHHHHHHHCCCCCEEEECCCCCCCCCC
FTLTDPVKSVWAKTQGKDYLTQMKSGVRFFDIRGRASADNMISVHHGMVYLHHELGKFLD
EEECHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCCCCCEEEECCCEEEEHHHHHHHHH
DAKYYLSAYPNETIVMSMKKDYDSDSKVTKTFEEIFREYYYNNPQYQNLFYTGSNANPTL
HHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCH
KETKGKIVLFNRMGGTYIKSGYGADTSGIQWADNATFETKINNGSLNLKVQDEYKDYYDK
HHCCCCEEEEECCCCCEEECCCCCCCCCCEECCCCEEEEEECCCEEEEEECHHHHHHHHH
KVEAVKNLLAKAKTDSNKDNVYVNFLSVASGGSAFNSTYNYASHINPEIAKTIKENGKAR
HHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCHHCCCCCHHHHCCHHHHHHHHHCCCCE
TGWLIVDYAGYPWPGYDDIVSEIIDSNK
ECEEEEECCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8225585 [H]