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The map label for this gene is yrkH [H]

Identifier: 15925791

GI number: 15925791

Start: 92616

End: 93950

Strand: Direct

Name: yrkH [H]

Synonym: SA0083

Alternate gene names: 15925791

Gene position: 92616-93950 (Clockwise)

Preceding gene: 15925790

Following gene: 15925792

Centisome position: 3.29

GC content: 33.48

Gene sequence:

>1335_bases
ATGTTTTTTAAACAGTTTTACGATAATCATTTATCTCAAGCATCATATTTAGTGGGTTGTCAACGTACAGGAGAGGCAAT
AATAATAGACCCTGTTCGTGATTTATCGAAATATATAGAAGTTGCAGATTCTGAAGGTTTAACAATTACACAAGCTACAG
AAACACATATTCATGCTGATTTTGCTTCAGGAATTCGTGATGTGGCTAAACGCTTAAATGCAAATATATATGTGTCTGGC
GAAGGTGAAGATGCATTAGGGTATAAAAATATGCCATCAAAAACACAATTTGTTAAACATGGAGATATCATTCAAGTAGG
CAATGTTAAATTAGAAGTTCTGCATACTCCAGGACACACGCCTGAAAGTATTAGCTTTTTACTCACTGATTTAGGTGGTG
GTTCAAGTGTTCCGATGGGATTATTTAGTGGTGACTTTATTTTTGTTGGTGATATAGGTAGACCTGATTTATTAGAAAAA
TCTGTTCAAATAAAGGGTTCTACAGAAATTAGCGCGAAACAAATGTATGAGTCCGTTCAAAATATTAAAAATTTACCAGA
CTATGTTCAAATCTGGCCGGGTCATGGTGCTGGAAGCCCTTGTGGTAAAGCATTAGGTGCCATACCTATATCTACAATAG
GTTATGAGAAAATTAATAACTGGGCATTTAATGAAATTGATGAGACTAAATTTATTGAATCATTAACATCAAATCAACCA
GCACCACCGCATCATTTTGCACAAATGAAACAAGTTAATCAGTTTGGTATGAATTTATATCAATCATATGATGTTTATCC
TAGTTTAGATAATAAGAGAGTAGCATTTGATCTTCGTAGCAAAGAGGCCTTTCACGGTGGCCACACAAAAGGAACAATCA
ATATACCATACAACAAAAACTTTATTAATCAAATTGGTTGGTACTTAGATTTTGAAAAAGATATAGATTTAATTGGAGAT
AAATCTACTGTTGAGAAAGCGAAACACACTTTACAATTAATTGGGTTTGATAAGGTAGCAGGCTATCGTTTGCCAAAATC
AGGCATTTCAACCCAGTCCGTTCATAGCGCTGATATGACAGGTAAAGAAGAACATGTATTAGACGTACGTAATGATGAAG
AGTGGAATAATGGACACTTAGATCAAGCAGTTAATATTCCACATGGTAAATTATTAAATGAAAATATTCCTTTTAATAAA
GAGGATAAAATATATGTACATTGTCAGTCAGGTGTTAGAAGTTCAATTGCAGTGGGTATATTGGAAAGCAAAGGTTTTGA
AAATGTGGTGAATATTAGAGAAGGCTATCAAGATTTTCCAGAATCATTAAAATAA

Upstream 100 bases:

>100_bases
AGTTGAGTACGGTGGTGTAGGCACTTATATTGGTGCTACTGAAAATGCGAATCATAATTTATTTATCTAATTAAATCTAT
TAATAAAAGGAGTTGTTATC

Downstream 100 bases:

>100_bases
TTTAAGGATGTGGAAAAAATGAATAAGCATTATCAAATTGTTATTATTGGTGGCGGTACAGCAGGTGTTACCGTAGCATC
AAGACTATTAAGAAAAAATC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MFFKQFYDNHLSQASYLVGCQRTGEAIIIDPVRDLSKYIEVADSEGLTITQATETHIHADFASGIRDVAKRLNANIYVSG
EGEDALGYKNMPSKTQFVKHGDIIQVGNVKLEVLHTPGHTPESISFLLTDLGGGSSVPMGLFSGDFIFVGDIGRPDLLEK
SVQIKGSTEISAKQMYESVQNIKNLPDYVQIWPGHGAGSPCGKALGAIPISTIGYEKINNWAFNEIDETKFIESLTSNQP
APPHHFAQMKQVNQFGMNLYQSYDVYPSLDNKRVAFDLRSKEAFHGGHTKGTINIPYNKNFINQIGWYLDFEKDIDLIGD
KSTVEKAKHTLQLIGFDKVAGYRLPKSGISTQSVHSADMTGKEEHVLDVRNDEEWNNGHLDQAVNIPHGKLLNENIPFNK
EDKIYVHCQSGVRSSIAVGILESKGFENVVNIREGYQDFPESLK

Sequences:

>Translated_444_residues
MFFKQFYDNHLSQASYLVGCQRTGEAIIIDPVRDLSKYIEVADSEGLTITQATETHIHADFASGIRDVAKRLNANIYVSG
EGEDALGYKNMPSKTQFVKHGDIIQVGNVKLEVLHTPGHTPESISFLLTDLGGGSSVPMGLFSGDFIFVGDIGRPDLLEK
SVQIKGSTEISAKQMYESVQNIKNLPDYVQIWPGHGAGSPCGKALGAIPISTIGYEKINNWAFNEIDETKFIESLTSNQP
APPHHFAQMKQVNQFGMNLYQSYDVYPSLDNKRVAFDLRSKEAFHGGHTKGTINIPYNKNFINQIGWYLDFEKDIDLIGD
KSTVEKAKHTLQLIGFDKVAGYRLPKSGISTQSVHSADMTGKEEHVLDVRNDEEWNNGHLDQAVNIPHGKLLNENIPFNK
EDKIYVHCQSGVRSSIAVGILESKGFENVVNIREGYQDFPESLK
>Mature_444_residues
MFFKQFYDNHLSQASYLVGCQRTGEAIIIDPVRDLSKYIEVADSEGLTITQATETHIHADFASGIRDVAKRLNANIYVSG
EGEDALGYKNMPSKTQFVKHGDIIQVGNVKLEVLHTPGHTPESISFLLTDLGGGSSVPMGLFSGDFIFVGDIGRPDLLEK
SVQIKGSTEISAKQMYESVQNIKNLPDYVQIWPGHGAGSPCGKALGAIPISTIGYEKINNWAFNEIDETKFIESLTSNQP
APPHHFAQMKQVNQFGMNLYQSYDVYPSLDNKRVAFDLRSKEAFHGGHTKGTINIPYNKNFINQIGWYLDFEKDIDLIGD
KSTVEKAKHTLQLIGFDKVAGYRLPKSGISTQSVHSADMTGKEEHVLDVRNDEEWNNGHLDQAVNIPHGKLLNENIPFNK
EDKIYVHCQSGVRSSIAVGILESKGFENVVNIREGYQDFPESLK

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI21703352, Length=218, Percent_Identity=28.4403669724771, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI116642887, Length=218, Percent_Identity=28.4403669724771, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI14150041, Length=188, Percent_Identity=30.8510638297872, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI46361987, Length=188, Percent_Identity=30.8510638297872, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI94538320, Length=188, Percent_Identity=30.3191489361702, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI94538322, Length=188, Percent_Identity=30.3191489361702, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787158, Length=226, Percent_Identity=30.0884955752212, Blast_Score=92, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17538952, Length=196, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17536925, Length=171, Percent_Identity=31.5789473684211, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI221330176, Length=200, Percent_Identity=28, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR001763 [H]

Pfam domain/function: PF00753 Lactamase_B; PF00581 Rhodanese [H]

EC number: NA

Molecular weight: Translated: 49352; Mature: 49352

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFKQFYDNHLSQASYLVGCQRTGEAIIIDPVRDLSKYIEVADSEGLTITQATETHIHAD
CCHHHHHHHHHHHHHHEEEECCCCCEEEECCHHHHHHHHHHCCCCCCEEEECCCHHHHHH
FASGIRDVAKRLNANIYVSGEGEDALGYKNMPSKTQFVKHGDIIQVGNVKLEVLHTPGHT
HHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHCCCCEEEECCEEEEEEECCCCC
PESISFLLTDLGGGSSVPMGLFSGDFIFVGDIGRPDLLEKSVQIKGSTEISAKQMYESVQ
CHHHHEEEEECCCCCCCCCEEECCCEEEEECCCCCHHHHHCEEECCCCCHHHHHHHHHHH
NIKNLPDYVQIWPGHGAGSPCGKALGAIPISTIGYEKINNWAFNEIDETKFIESLTSNQP
HHHCCCCCEEEECCCCCCCHHHHHHCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCC
APPHHFAQMKQVNQFGMNLYQSYDVYPSLDNKRVAFDLRSKEAFHGGHTKGTINIPYNKN
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHCCCCCCEEEECCCCCC
FINQIGWYLDFEKDIDLIGDKSTVEKAKHTLQLIGFDKVAGYRLPKSGISTQSVHSADMT
HHHHHCCEEEECCCCCCCCCHHHHHHHHHHEEEEEEHHHCCCCCCCCCCCCCCCCCCCCC
GKEEHVLDVRNDEEWNNGHLDQAVNIPHGKLLNENIPFNKEDKIYVHCQSGVRSSIAVGI
CCCCEEEECCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCEEEEEECCCCCCCEEEEE
LESKGFENVVNIREGYQDFPESLK
HHCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFFKQFYDNHLSQASYLVGCQRTGEAIIIDPVRDLSKYIEVADSEGLTITQATETHIHAD
CCHHHHHHHHHHHHHHEEEECCCCCEEEECCHHHHHHHHHHCCCCCCEEEECCCHHHHHH
FASGIRDVAKRLNANIYVSGEGEDALGYKNMPSKTQFVKHGDIIQVGNVKLEVLHTPGHT
HHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHCCCCEEEECCEEEEEEECCCCC
PESISFLLTDLGGGSSVPMGLFSGDFIFVGDIGRPDLLEKSVQIKGSTEISAKQMYESVQ
CHHHHEEEEECCCCCCCCCEEECCCEEEEECCCCCHHHHHCEEECCCCCHHHHHHHHHHH
NIKNLPDYVQIWPGHGAGSPCGKALGAIPISTIGYEKINNWAFNEIDETKFIESLTSNQP
HHHCCCCCEEEECCCCCCCHHHHHHCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCC
APPHHFAQMKQVNQFGMNLYQSYDVYPSLDNKRVAFDLRSKEAFHGGHTKGTINIPYNKN
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHCCCCCCEEEECCCCCC
FINQIGWYLDFEKDIDLIGDKSTVEKAKHTLQLIGFDKVAGYRLPKSGISTQSVHSADMT
HHHHHCCEEEECCCCCCCCCHHHHHHHHHHEEEEEEHHHCCCCCCCCCCCCCCCCCCCCC
GKEEHVLDVRNDEEWNNGHLDQAVNIPHGKLLNENIPFNKEDKIYVHCQSGVRSSIAVGI
CCCCEEEECCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCEEEEEECCCCCCCEEEEE
LESKGFENVVNIREGYQDFPESLK
HHCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]