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The map label for this gene is gntR [H]

Identifier: 15925497

GI number: 15925497

Start: 2648952

End: 2649632

Strand: Reverse

Name: gntR [H]

Synonym: SAV2507

Alternate gene names: 15925497

Gene position: 2649632-2648952 (Counterclockwise)

Preceding gene: 15925498

Following gene: 15925496

Centisome position: 92.05

GC content: 35.54

Gene sequence:

>681_bases
ATGATGTATGGATATCCAGAGAAATGGTTGGAAGGTATGACAACTGGAGAAGGTATCGCGGCAGAATTACGCTTAGGTAT
TGTGAATGGTCACATAGCTGAAGGTACGTTACTCACTGAAAATCAAATGGCAAAGCAATTTAATGTGAGTCGTTCGCCAA
TTCGAGATGCATTTAAATTATTGCAACAAAATCAACTCATCCAATTAGAAAGAATGGGTGCACATGTGTTGCCGTTTGGG
GAACAAGAAAAGAAAGAAATGTACGATTTGCGACTGATGCTAGAGTCATTTGCATTTTCAAGAGTTAAAAATCAAGAGAG
ACTACCTATCGTAAAAGAAATGAAGAAACAACTTGAAATGATGAAAGTGGCAGTAAAATTTGAAGATGCAGAATCATTTA
CGAAGCATGACTTTGAATTTCATGAAACATTAATCAAAGCATCTAACCACCAATATTTAAACTCATTTTGGAGTCATTTA
AAACCAGTAATGATGGCACTCGTTTTAACATCCATGCGACAACGTATGCAACAGAACCCGCAAGATTTTGAACGCATACA
TCATAATCATCAAGTGTTTATTGATGCAGTGGAACAATACGACAGTCAAATTTTGAAGGAAGCGTTTCATTTAAATTTTG
ACGATGTTGGTAAAGATATTGAAGGATTTTGGTTGAATTAA

Upstream 100 bases:

>100_bases
GTCACTATTTTAGTTCGCATAAAGAAAGCGCTTGCAAACACTTAAGAACTATATTAACATACTTGTATACAAGTATGTCA
TGTAATGAAGGAGTGCTTTG

Downstream 100 bases:

>100_bases
AATGAAAGAAAGAAGGATTTATCATGAAATATATGATTGGTGTCGACATTGGAACGACGAGTACCAAGTCAGTCTTATAT
GATGAAAATGGAGCTTTTAT

Product: gluconate operon transcriptional repressor

Products: NA

Alternate protein names: P28 protein [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MMYGYPEKWLEGMTTGEGIAAELRLGIVNGHIAEGTLLTENQMAKQFNVSRSPIRDAFKLLQQNQLIQLERMGAHVLPFG
EQEKKEMYDLRLMLESFAFSRVKNQERLPIVKEMKKQLEMMKVAVKFEDAESFTKHDFEFHETLIKASNHQYLNSFWSHL
KPVMMALVLTSMRQRMQQNPQDFERIHHNHQVFIDAVEQYDSQILKEAFHLNFDDVGKDIEGFWLN

Sequences:

>Translated_226_residues
MMYGYPEKWLEGMTTGEGIAAELRLGIVNGHIAEGTLLTENQMAKQFNVSRSPIRDAFKLLQQNQLIQLERMGAHVLPFG
EQEKKEMYDLRLMLESFAFSRVKNQERLPIVKEMKKQLEMMKVAVKFEDAESFTKHDFEFHETLIKASNHQYLNSFWSHL
KPVMMALVLTSMRQRMQQNPQDFERIHHNHQVFIDAVEQYDSQILKEAFHLNFDDVGKDIEGFWLN
>Mature_226_residues
MMYGYPEKWLEGMTTGEGIAAELRLGIVNGHIAEGTLLTENQMAKQFNVSRSPIRDAFKLLQQNQLIQLERMGAHVLPFG
EQEKKEMYDLRLMLESFAFSRVKNQERLPIVKEMKKQLEMMKVAVKFEDAESFTKHDFEFHETLIKASNHQYLNSFWSHL
KPVMMALVLTSMRQRMQQNPQDFERIHHNHQVFIDAVEQYDSQILKEAFHLNFDDVGKDIEGFWLN

Specific function: Transcriptional repressor of the gluconate operon (gntRKPZ), which encodes the proteins for gluconate utilization. Represses mRNA synthesis by binding to the gnt operator; the binding is suppressed by gluconate or glucono-delta-lactone [H]

COG id: COG1802

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26596; Mature: 26596

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMYGYPEKWLEGMTTGEGIAAELRLGIVNGHIAEGTLLTENQMAKQFNVSRSPIRDAFKL
CCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEECHHHHHHHHCCCCCHHHHHHHH
LQQNQLIQLERMGAHVLPFGEQEKKEMYDLRLMLESFAFSRVKNQERLPIVKEMKKQLEM
HHHCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
MKVAVKFEDAESFTKHDFEFHETLIKASNHQYLNSFWSHLKPVMMALVLTSMRQRMQQNP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
QDFERIHHNHQVFIDAVEQYDSQILKEAFHLNFDDVGKDIEGFWLN
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
>Mature Secondary Structure
MMYGYPEKWLEGMTTGEGIAAELRLGIVNGHIAEGTLLTENQMAKQFNVSRSPIRDAFKL
CCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEECHHHHHHHHCCCCCHHHHHHHH
LQQNQLIQLERMGAHVLPFGEQEKKEMYDLRLMLESFAFSRVKNQERLPIVKEMKKQLEM
HHHCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
MKVAVKFEDAESFTKHDFEFHETLIKASNHQYLNSFWSHLKPVMMALVLTSMRQRMQQNP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
QDFERIHHNHQVFIDAVEQYDSQILKEAFHLNFDDVGKDIEGFWLN
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3020045; 7584049; 9384377; 2419835; 8510140 [H]