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The map label for this gene is sarH3 [H]

Identifier: 15925488

GI number: 15925488

Start: 2634548

End: 2634907

Strand: Reverse

Name: sarH3 [H]

Synonym: SAV2498

Alternate gene names: 15925488

Gene position: 2634907-2634548 (Counterclockwise)

Preceding gene: 15925490

Following gene: 15925487

Centisome position: 91.54

GC content: 22.78

Gene sequence:

>360_bases
TTGATGAATGATTTGAAAAGCAAGAGCAATATTAAATTAATGAAAAGAGTATTAACTACATATGAGCTGCGTAAATATTT
AAAAAAATATTTTTGTCTTACATTAGATAATTATTTAGTATTAGCATATTTAGATGTATTTAAAAATGATGAAGGTAAAT
ATTTTATGAGAGACATTATAAGTTATATCGGTATAGACCAATCTAGAATTGTTAAAAGCGTAAAAGAATTATCAAAAAAG
GGTTACTTGAATAAATGTAGAGACCCACATGATAGTAGAAATGTAATCATTGTTGTTTCTGTAAAACAACACAATTATAT
TAAAAATCTTTTGAGTGAAATAAATATTAATGAAACATAA

Upstream 100 bases:

>100_bases
TGTGTTTATAGCTAGCACCACAAACTAAATATATTTGGAGTTATTACTAGTTAAAGACAAATATTATTTGACGTGACAAT
TAAAAGTAAGGGATGAAGAC

Downstream 100 bases:

>100_bases
AGTATGTTTCGAGATTTTAATATCTTGGTGCAGTTAAATGTATTTTTAAATGCGTTAAGGTATTTTTTATTTTAGAAATT
CAATGCTATTGAGTTGATGG

Product: accessory regulator A-like protein

Products: NA

Alternate protein names: Staphylococcal accessory regulator T [H]

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MMNDLKSKSNIKLMKRVLTTYELRKYLKKYFCLTLDNYLVLAYLDVFKNDEGKYFMRDIISYIGIDQSRIVKSVKELSKK
GYLNKCRDPHDSRNVIIVVSVKQHNYIKNLLSEININET

Sequences:

>Translated_119_residues
MMNDLKSKSNIKLMKRVLTTYELRKYLKKYFCLTLDNYLVLAYLDVFKNDEGKYFMRDIISYIGIDQSRIVKSVKELSKK
GYLNKCRDPHDSRNVIIVVSVKQHNYIKNLLSEININET
>Mature_119_residues
MMNDLKSKSNIKLMKRVLTTYELRKYLKKYFCLTLDNYLVLAYLDVFKNDEGKYFMRDIISYIGIDQSRIVKSVKELSKK
GYLNKCRDPHDSRNVIIVVSVKQHNYIKNLLSEININET

Specific function: Transcriptional regulator acting as an intermediary between major regulators sarA and agr and virulence genes. Represses alpha-hemolysin (hla) gene expression. Down-regulates agr RNAIII expression by repressing sarU, a positive activator of agr expression

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sarA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010166
- InterPro:   IPR011991 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 14134; Mature: 14134

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNDLKSKSNIKLMKRVLTTYELRKYLKKYFCLTLDNYLVLAYLDVFKNDEGKYFMRDII
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SYIGIDQSRIVKSVKELSKKGYLNKCRDPHDSRNVIIVVSVKQHNYIKNLLSEININET
HHHCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEEEEECHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MMNDLKSKSNIKLMKRVLTTYELRKYLKKYFCLTLDNYLVLAYLDVFKNDEGKYFMRDII
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SYIGIDQSRIVKSVKELSKKGYLNKCRDPHDSRNVIIVVSVKQHNYIKNLLSEININET
HHHCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEEEEECHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12496184 [H]