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The map label for this gene is opuCB [H]

Identifier: 15925437

GI number: 15925437

Start: 2582328

End: 2582963

Strand: Reverse

Name: opuCB [H]

Synonym: SAV2447

Alternate gene names: 15925437

Gene position: 2582963-2582328 (Counterclockwise)

Preceding gene: 15925438

Following gene: 15925436

Centisome position: 89.73

GC content: 35.85

Gene sequence:

>636_bases
ATGATTGAGTTCCTACATGAACATGGTGGACAGTTGATGTCGAAAACACTGGAACATTTTTATATTTCTATAGTGGCATT
ATTACTTGCCATCATTGTTGCAGTACCTATAGGCATTTTATTATCAAAAACAAAGCGAACTGCCAATATTGTATTAACTG
TGGCAGGTGTCTTACAAACTATTCCAACACTAGCTGTACTTGCTATTATGATACCGATTTTTGGTGTTGGTAAAACGCCT
GCAATTGTAGCGCTATTTATTTATGTATTATTACCTATTTTAAATAACACGGTACTCGGTGTTCAAAATATTGATAGCAA
CATTAAAGAAGCTGGAAAAAGTATGGGAATGACACAATTTCAATTGATGAAGGATGTTGAATTGCCGTTAGCATTGCCGC
TTATCATTGGTGGCATTCGTTTGTCATCTGTGTATGTAATTAGTTGGGCTACACTTGCAAGTTATGTAGGTGCGGGTGGA
TTAGGTGATTTCATTTTCAATGGTTTAAATTTATATGATCCACTGATGATTGTAACTGCAACGGTACTCGTTACTGCACT
AGCATTAGGTGTTGATGCCTTATTAGCTTTAGTTGAAAAATGGGTAGTTCCCAAAGGCTTAAAAGTATCTGGATAA

Upstream 100 bases:

>100_bases
CAGTGCAAACAGAACATGTGGGGGAAGACACTGTGTCCTCAAAAATGCATGAGCAACACACTACTAATGTCAAAGTACGT
GACATAGGAGATGATAAATC

Downstream 100 bases:

>100_bases
TTAGGAGGCTAAGATAATGAAGAAAATTAAATATATACTTGTCGTGTTTGTCTTATCGCTTACCGTATTATCTGGATGTA
GTTTGCCCGGACTAGGTAGT

Product: glycine betaine/carnitine/choline ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MIEFLHEHGGQLMSKTLEHFYISIVALLLAIIVAVPIGILLSKTKRTANIVLTVAGVLQTIPTLAVLAIMIPIFGVGKTP
AIVALFIYVLLPILNNTVLGVQNIDSNIKEAGKSMGMTQFQLMKDVELPLALPLIIGGIRLSSVYVISWATLASYVGAGG
LGDFIFNGLNLYDPLMIVTATVLVTALALGVDALLALVEKWVVPKGLKVSG

Sequences:

>Translated_211_residues
MIEFLHEHGGQLMSKTLEHFYISIVALLLAIIVAVPIGILLSKTKRTANIVLTVAGVLQTIPTLAVLAIMIPIFGVGKTP
AIVALFIYVLLPILNNTVLGVQNIDSNIKEAGKSMGMTQFQLMKDVELPLALPLIIGGIRLSSVYVISWATLASYVGAGG
LGDFIFNGLNLYDPLMIVTATVLVTALALGVDALLALVEKWVVPKGLKVSG
>Mature_211_residues
MIEFLHEHGGQLMSKTLEHFYISIVALLLAIIVAVPIGILLSKTKRTANIVLTVAGVLQTIPTLAVLAIMIPIFGVGKTP
AIVALFIYVLLPILNNTVLGVQNIDSNIKEAGKSMGMTQFQLMKDVELPLALPLIIGGIRLSSVYVISWATLASYVGAGG
LGDFIFNGLNLYDPLMIVTATVLVTALALGVDALLALVEKWVVPKGLKVSG

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=181, Percent_Identity=39.2265193370166, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1788451, Length=197, Percent_Identity=30.4568527918782, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1789033, Length=172, Percent_Identity=30.2325581395349, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1786564, Length=148, Percent_Identity=28.3783783783784, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 22386; Mature: 22386

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEFLHEHGGQLMSKTLEHFYISIVALLLAIIVAVPIGILLSKTKRTANIVLTVAGVLQT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPTLAVLAIMIPIFGVGKTPAIVALFIYVLLPILNNTVLGVQNIDSNIKEAGKSMGMTQF
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHCCHHHH
QLMKDVELPLALPLIIGGIRLSSVYVISWATLASYVGAGGLGDFIFNGLNLYDPLMIVTA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHH
TVLVTALALGVDALLALVEKWVVPKGLKVSG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MIEFLHEHGGQLMSKTLEHFYISIVALLLAIIVAVPIGILLSKTKRTANIVLTVAGVLQT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPTLAVLAIMIPIFGVGKTPAIVALFIYVLLPILNNTVLGVQNIDSNIKEAGKSMGMTQF
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHCCHHHH
QLMKDVELPLALPLIIGGIRLSSVYVISWATLASYVGAGGLGDFIFNGLNLYDPLMIVTA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHH
TVLVTALALGVDALLALVEKWVVPKGLKVSG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]