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The map label for this gene is tcyB [H]

Identifier: 15925403

GI number: 15925403

Start: 2541120

End: 2541614

Strand: Reverse

Name: tcyB [H]

Synonym: SAV2413

Alternate gene names: 15925403

Gene position: 2541614-2541120 (Counterclockwise)

Preceding gene: 15925404

Following gene: 15925402

Centisome position: 88.3

GC content: 34.34

Gene sequence:

>495_bases
ATGATAGTACAACTATTTATCATATTTTATGGTATTCCAGAATTAGGTAGATTATTAACAAATGACGCTGACAACCAATG
GACATTGGCACCTGTAGTGGCTGCTATTATTGGTTTATCATTAAATGTAGGTGCGTATGCTTCGGAAATTATTCGTGGCG
GTATTATTTCTATACCGAAAGGACAAACAGAAGCTGCATATTCCATCGGTATGACGTATGGTCAAACGATACAACGTATC
ATTTTACCGCAGGCAATTCGAGTGTCGATTCCTGCACTAGGTAATACATTTTTAAGTTTAATCAAAGATACATCATTATT
AGGATTTATTTTAGTGGCTGAAATGTTTAGAAAAGCTCAAGAAGTTGCGTCTACAACATATGAATATTTAACAATTTATG
TGTTAGTTGCGCTAATGTACTGGGTGGTATGCTTTATTATTTCAATTATCCAAGGTATCTATGAATCTTATATTGAAAGA
GGGTATCGCTCATGA

Upstream 100 bases:

>100_bases
ATTGATTATTGCATTATTTACAGCATTAATGCGAATTTCAACGAGTAAAATTTTAAGAAGTATTTCACGTGTCTATGTAT
CTATTATTCGAGGAACACCA

Downstream 100 bases:

>100_bases
TTCAATTGAACAATATCCATAAATCATTTAATGATGTTGAAGTCATCAAAGGTATTGATTTATCTGTTGAACAAGGTGAG
GTTGTAACCTTAATCGGTCG

Product: ABC transporter (permease protein)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MIVQLFIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLNVGAYASEIIRGGIISIPKGQTEAAYSIGMTYGQTIQRI
ILPQAIRVSIPALGNTFLSLIKDTSLLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIER
GYRS

Sequences:

>Translated_164_residues
MIVQLFIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLNVGAYASEIIRGGIISIPKGQTEAAYSIGMTYGQTIQRI
ILPQAIRVSIPALGNTFLSLIKDTSLLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIER
GYRS
>Mature_164_residues
MIVQLFIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLNVGAYASEIIRGGIISIPKGQTEAAYSIGMTYGQTIQRI
ILPQAIRVSIPALGNTFLSLIKDTSLLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIER
GYRS

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=163, Percent_Identity=47.8527607361963, Blast_Score=154, Evalue=4e-39,
Organism=Escherichia coli, GI1787030, Length=150, Percent_Identity=36.6666666666667, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI87082239, Length=137, Percent_Identity=37.956204379562, Blast_Score=94, Evalue=4e-21,
Organism=Escherichia coli, GI1787087, Length=125, Percent_Identity=33.6, Blast_Score=86, Evalue=9e-19,
Organism=Escherichia coli, GI1788646, Length=142, Percent_Identity=30.9859154929577, Blast_Score=82, Evalue=1e-17,
Organism=Escherichia coli, GI1786873, Length=129, Percent_Identity=35.6589147286822, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1788645, Length=145, Percent_Identity=27.5862068965517, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI48994930, Length=134, Percent_Identity=34.3283582089552, Blast_Score=73, Evalue=9e-15,
Organism=Escherichia coli, GI1787086, Length=128, Percent_Identity=32.03125, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1786874, Length=164, Percent_Identity=24.390243902439, Blast_Score=60, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 18182; Mature: 18182

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVQLFIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLNVGAYASEIIRGGIISIPK
CHHHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
GQTEAAYSIGMTYGQTIQRIILPQAIRVSIPALGNTFLSLIKDTSLLGFILVAEMFRKAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIERGYRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIVQLFIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLNVGAYASEIIRGGIISIPK
CHHHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
GQTEAAYSIGMTYGQTIQRIILPQAIRVSIPALGNTFLSLIKDTSLLGFILVAEMFRKAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIERGYRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]